Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia

Journal of Virology

Volumn 78, Issue 23, 2004, Pages 12762-12772

  Kalantari, Mina ^a   Calleja Macias, Itzel E ^a,d   Tewari, Devansu ^b   Hagmar, Bjørn ^e   Lie, Kathrine ^e   Barrera Saldana, Hugo A ^d   Wiley, Dorothy J ^c   Bernard, Hans Ulrich ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓN   (Mexico)

^e OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

DINUCLEOTIDE; VIRUS DNA;

ARTICLE; CELL DIFFERENTIATION; CELL POPULATION; CPG ISLAND; DNA INTEGRATION; DNA METHYLATION; DYSPLASIA; EPITHELIUM CELL; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; TANDEM REPEAT; UTERINE CERVIX CANCER; UTERINE CERVIX EPITHELIUM; VIRUS REPLICATION; VIRUS TRANSCRIPTION; WART VIRUS;

CELL LINE, TUMOR; CPG ISLANDS; DNA METHYLATION; DNA, VIRAL; FEMALE; GENOME, VIRAL; HUMANS; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; UTERINE CERVICAL NEOPLASMS;

EID: 8644243891     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.23.12762-12772.2004     Document Type: Article

References (52)

1. Ai, W., E. Toussaint, and A. Roman. 1999. CCAAT displacement protein binds to and negatively regulates human papillomavirus type 6 E6, E7, and E1 promoters. J. Virol. 73:4220-4229.
2. 1a.Badal, S., V. Badal, I. E. Calleja-Macias, M. Kalantari, L. S. H. Chuang, B. F. L. Li, and H. U. Bernard. 2004. The human papillomavirus-18 genome is efficiently targeted by cellular DNA methylation. Virology 324:483-492.
3. Badal, V., L. S. H. Chuang, E. H.-H. Tan, S. Badal, L. L. Villa, C. M. Wheeler, B. F. L. Li, and H.-U. Bernard. 2003. CpG methylation of human papillomavirus-16 DNA in cervical cancer cell lines and in clinical specimens: genomic hypomethylation correlates with carcinogenic progression. J. Virol. 77:6227-6234.
4. Bernard, H. U. 2002. Gene expression of genital human papillomaviruses and potential antiviral approaches. Antivir. Ther. 7:219-237.
5. Bestor, T. H., and B. Tycko. 1996. Creation of genomic methylation patterns. Nat. Genet. 12:363-367.
6. Bird, A. P. 1992. The essentials of DNA methylation. Cell 70:5-8.
7. Bosch, F. X., M. M. Manos, N. Munoz, M. Sherman, A. M. Jansen, J. Peto, M. H. Schiffman, V. Moreno, R. Kurman, K. V. Shah, et al. 1995. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. J. Natl. Cancer Inst. 87:796-802.
8. Brandeis, M., D. Frank, I. Keshet, Z. Siegfried, M. Mendelsohn, A. Nemes, V. Temper, A. Raxin, and H. Cedar. 1994. Sp1 elements protect a CpG island from de novo methylation. Nature 371:435-438.
9. Burgers, W. A., F. Fuks, and T. Kouzarides. 2002. DNA methyltransferases get connected to chromatin. Trends Genet. 18:275-277.
10. Burnett, T. S., and J. P. Sleeman. 1984. Uneven distribution of methylation sites within the human papillomavirus 1a genome: possible relevance to viral gene expression. Nucleic Acids Res. 12:8847-8860.
11. I. E. Calleja-Macias, M. Kalantari, J. Huh, R. Ortiz-Lopez, A. Rojas-Martinez, J. F. Gonzalez-Guerrero, A.-L. Williamson, B. Hagmar, D. J. Wiley, L. Villarreal, H.-U. Bernard, and H. A. Barrera-Saldaña. 2004. High prevalence of specific variants of human papillomavirus-16, 18, 31, and 35 in a Mexican population and relationship to European, African, and Native American variants. Virology 319:315-323.
12. Chan, W. K., G. Klock, and H.-U. Bernard. 1989. Progesterone and glucocorticoid response elements occur in the long control regions of several human papillomaviruses involved in anogenital neoplasia. J. Virol. 63:3261-3269.
13. Daniel, B., G. Mukherjee, L. Seshadri, E. Vallikad, and S. Krishna. 1995. Changes in the physical state and expression of human papillomavirus type 16 in the progression of cervical intraepithelial neoplasia lesions analysed by PCR. J. Gen. Virol. 76:2589-2593.
14. Danos, O., M. Katinka, and M. Yaniv. 1980. Molecular cloning, refined physical map and heterogeneity of methylation sites of papilloma virus type 1a DNA. Eur. J. Biochem. 109:457-461.
15. Dodge, J. E., B. H. Ramsahoye, Z. G. Wo, M. Okano, and E. Li. 2002. De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation. Gene 289:41-48.
16. Doerfler, W., Remus, R., Muller, K., Heller, H., Hohlweg, U., and R. Schubbert. 2001. The fate of foreign DNA in mammalian cells and organisms. Dev. Biol. (Basel) 106:89-97.
17. Frommer, M., L. E. McDonald, D. S. Millar, C. M. Collis, F. Watt, G. W. Grigg, P. L. Molloy, and C. L. Paul. 1992. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc. Natl. Acad. Sci. USA 89:1827-1831.
18. Harrington, M. A., P. A. Jones, M. Imagawa, and M. Karin. 1988. Cytosine methylation does not affect binding of transcription factor Sp1. Proc. Natl. Acad. Sci. USA 85:2066-2070.
19. Herman, J. G., and S. B. Baylin. 2000. Promoter-region hypermethylation and gene silencing in human cancer, p. 35-54. In P. A. Jones and P. K. Vogt (ed.), DNA methylation and cancer. Springer, Berlin, Germany.
20. Jaenisch, R., and A. Bird. 2003. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33:245-254.
21. Jones, P. A. 2003. Epigenetics in carcinogenesis and cancer prevention. Ann. N. Y. Acad. Sci. 983:213-219.
22. Jones, P. L., P. A. Wade, and A. P. Wolffe. 2001. Purification of the MeCP2/histone deacetylase complex from Xenopus laevis. Methods Mol. Biol. 181:297-307.
23. Kim, K., P. A. Garner-Hamrick, C. Fisher, D. Lee, and P. F. Lambert. 2003. Methylation patterns of papillomavirus DNA, its influence on E2 function, and implications in viral infection. J. Virol. 77:12450-12459.
24. Liang, G., M. F. Chan, Y. Tomigahara, Y. C. Tsai, F. A. Gonzales, E. Li, P. W. Laird, and P. A. Jones. 2002. Cooperativiry between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol. Cell. Biol. 22:480-491.
25. Myers, G., H. U. Bernard, H. Delius, M. Favre, J. Iconogle, M. van Ranst, and C. Wheeler (ed.). 1994. Human papillomaviruses: 1994 compendium, p. 1-A-3 to 1-A-8. Los Alamos National Laboratory, Los Alamos, N. Mex.
26. Nguyen, C., G. Liang, T. T. Nguyen, D. Tsao-Wei, S. Groshen, M. Lubbert, J. H. Zhou, W. F. Benedict, and P. A. Jones. 2001. Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells. J. Natl. Cancer Inst. 93:1465-1472.
27. O'Connor, M. J., W. Stünkel, C.-H. Koh, H. Zimmermann, and H.-U. Bernard. 2000. The differentiation-specific factor CDP/Cut represses transcription and replication of human papillomaviruses through a conserved silencing element. J. Virol. 70:401-410.
28. Okano, M., D. W. Bell, D. A. Haber, and E. Li. 1999. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99:247-257.
29. Okuwaki, M., and A. Verreault. 2004. Maintenance DNA methylation of nucleosome core particles. J. Biol. Chem. 279:2904-2912.
30. Pater, M. M., G. A. Hughes, D. E. Hyslop, H. Nakshatri, and A. Pater. 1988. Glucocorticoid-dependent oncogenic transformation by type 16 but not type 11 human papilloma virus DNA. Nature 335:832-835.
31. Ramsahoye, B. H., D. Biniszkiewicz, F. Lyko, V. Clark, A. P. Bird, and R. Jaenisch. 2000. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc. Natl. Acad. Sci. USA 97:5237-5242.
32. Rhee, I., K. E. Bachman, B. H. Park, K. W. Jair, R. W. Yen, K. E. Schuebel, H. Cui, A. P. Feinberg, C. Lengauer, K. W. Kinzler, S. B. Baylin, and B. Vogelstein. 2002. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416:552-556.
33. Robertson, K. D., E. Uzvolgyi, G. Liang, C. Talmadge, J. Sumegi. F. A. Gonzales, and P. A. Jones. 1999. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res. 27:2291-2298.
34. Robertson, K.D. 2000. The role of DNA methylation in modulating Epstein-Barr virus gene expression, p. 21-34. In P. A. Jones and P. K. Vogt (ed.), DNA methylation and cancer. Springer Verlag, Berlin, Germany.
35. Rosl, F., A. Arab, B. Klevenz, and H. zur Hausen. 1993. The effect of DNA methylation on gene regulation of human papillomaviruses. J. Gen. Virol. 74:791-801.
36. Schiffman, M. H., and L. A. Brinton. 1995. The epidemiology of cervical carcinogenesis. Cancer 76:1888-1901.
37. Schwarz, E., U. K. Freese, L. Gissmann, W. Mayer, B. Roggenbuck, A. Stremlau, and H. zur Hausen. 1985. Structure and transcription of human papillomavirus sequences in cervical carcinoma cells. Nature 314:111-114.
38. Stoler, M. H., C. R. Rhodes, A. Whitbeck, S. M. Wolinsky, L. T. Chow, and T. R. Broker. 1992. Human papillomavirus type 16 and 18 gene expression in cervical neoplasias. Hum. Pathol. 23:117-128.
39. Stünkel, W., Z. Huang, S. H. Tan, M. O'Connor, and H.-U. Bernard. 2000. Nuclear matrix attachment regions of human papillomavirus type 16 repress or activate the E6 promoter, depending on the physical state of the viral DNA. J. Virol. 74:2489-2501.
40. Stünkel, W., and H.-U. Bernard. 1999. The chromatin structure of the long control region of human papillomavirus type 16 represses viral oncoprotein expression. J. Virol. 73:1918-1930.
41. Sugawara, K., K. Fujinaga, Y. Yamashita, and Y. Ito. 1983. Integration and methylation of shope papilloma virus DNA in the transplantable Vx2 and Vx7 rabbit carcinomas. Virology 131:88-99.
42. Sutter, D., and W. Doerfler. 1980. Methylation of integrated adenovirus type 12 DNA sequences in transformed cells is inversely correlated with viral gene expression. Proc. Natl. Acad. Sci. USA 77:253-256.
43. Tan, S. H., C. C. Baker, W. Stünkel, and H. U. Bernard. 2003. A transcriptional initiator overlaps with a conserved YY1 site in the long control region of human papillomavirus type 16. Virology 305:486-501.
44. Tan, S. H., L. E. C. Leong, P. A. Walker, and H. U. Bernard. 1994. The human papillomavirus type 16 transcription factor E2 binds with low cooperativity to two flanking binding sites and represses the E6 promoter through displacement of Sp1 and TFIID. J. Virol. 68:6411-6420.
45. Thain, A., O. Jenkins. A. R. Clarke, and K. Gaston. 1996. CpG methylation directly inhibits binding of the human papillomavirus type 16 E2 protein to specific DNA sequences. J. Virol. 70:7233-7235.
46. 44a.Toth, M., U. Muller, and W. Doerfler. 1990. Establishment of de novo DNA methylation patterns. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter. J. Mol. Biol. 214:673-683.
47. Van Tine, B. A., J. Knops, T. R. Broker, L. T. Chow, and P. T. Moen. 2001. In situ analysis of the transcriptional activity of integrated viral DNA using tyramide-FISH. Dev. Biol. (Basel) 106:381-385.
48. Walboomers, J. M., M. V. Jacobs, M. M. Manos, F. X. Bosch, J. A. Kummer, K. V. Shah, P. J. Snijders, J. Peto, C. J. Meijer, and N. Munoz. 1999. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J. Pathol. 189:12-19.
49. Wettstein, F. O., and J. G. Stevens. 1983. Shope papilloma virus DNA is extensively methylated in non-virus-producing neoplasms. Virology 126:493-504.
50. 47a.Woodcock, D. M., P. J. Crowther, S. Jefferson, and W. P. Diver. 1988. Methylation at dinucleotides other than CpG: implications for human maintenance methylation. Gene 74:151-152.
51. Yoder, J. A., C. P. Walsh, and T. H. Bester. 1997. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 13:335-340.
52. zur Hausen, H. 2002. Papillomaviruses and cancer: from basic studies to clinical application. Nat. Rev. Cancer 2:342-350.