APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer

International Journal of Cancer

Volumn 119, Issue 10, 2006, Pages 2272-2278

  Iacopetta, Barry ^a   Grieu, Fabienne ^a   Li, Wei ^a   Ruszkiewicz, Andrew ^b   Caruso, Maria ^b   Moore, James ^c   Watanabe, Goh ^d   Kawakami, Kazuyuki ^d  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^c ROYAL ADELAIDE HOSPITAL   (Australia)

^d KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

APC; CIMP; Colorectal cancer; Microsatellite instability

Indexed keywords

APC PROTEIN; B RAF KINASE; DEATH ASSOCIATED PROTEIN KINASE; METHYL GROUP; METHYLENETETRAHYDROFOLIC ACID; PROTEIN MLH1; PROTEIN P14; PROTEIN P16; TETRAHYDROFOLIC ACID; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DEATH ASSOCIATED PROTEIN KINASE GENE; DNA METHYLATION; FEMALE; GENE LOCATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SELECTION; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MH1 GENE; MICROSATELLITE INSTABILITY; NUCLEOTIDE SEQUENCE; ONCOGENE; P14 GENE; P16 GENE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN METHYLATION; QUANTITATIVE ANALYSIS; TISSUE INHIBITOR OF METALLOPROTEINASE 3 GENE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR SUPPRESSOR GENE;

CARRIER PROTEINS; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; GENES, APC; GENES, P16; HUMANS; MICROSATELLITE REPEATS; NUCLEAR PROTEINS; PHENOTYPE; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; TISSUE INHIBITOR OF METALLOPROTEINASE-3; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33749625622     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22237     Document Type: Article

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