Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation

Cancer Research

Volumn 68, Issue 8, 2008, Pages 3049-3056

  Leng, Shuguang ^a   Stidley, Christine A ^b   Willink, Randy ^a   Bernauer, Amanda ^a   Do, Kieu ^a   Picchi, Maria A ^a   Sheng, Xin ^d   Frasco, Melissa A ^d   Van Den Berg, David ^d   Gilliland, Frank D ^d   Zima, Christopher ^b   Crowell, Richard E ^b,c   Belinsky, Steven A ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c NEW MEXICO VA HEALTH CARE SYSTEM   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BIOLOGICAL MARKER; DOUBLE STRANDED DNA;

ACCURACY; ADULT; AGED; ALLELE; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CHEK2 GENE; COHORT ANALYSIS; CONTROLLED STUDY; DNA DAMAGE; DNA METHYLATION; DNA PKC GENE; DNA REPAIR; EARLY DIAGNOSIS; FEMALE; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; LUNG CANCER; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; MOLECULAR RECOGNITION; MRE11A GENE; NBN GENE; PRIORITY JOURNAL; PROMOTER REGION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SPUTUM ANALYSIS; XRCC3 GENE;

DNA DAMAGE; DNA METHYLATION; DNA REPAIR; DNA-BINDING PROTEINS; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; SMOKING; VARIATION (GENETICS);

EID: 42349114374     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-6344     Document Type: Article

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