The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses
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Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells
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Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
Wolf SF, Temple PA, Kobayashi M, et al. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J Immunol 1991;146:3074-81.
Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones
Manetti R, Gerosa F, Giudizi MG, et al. Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones. J Exp Med 1994;179:1273-83.
IL-12-deficient mice are defective but not devoid of type 1 cytokine responses
Magram J, Sfarra J, Connaughton S, et al. IL-12-deficient mice are defective but not devoid of type 1 cytokine responses. Ann N Y Acad Sci 1996;795:60-70.
A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits
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Presky DH, Yang H, Minetti LJ, et al. A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci U S A 1996;93:14002-7.
Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130
Chua AO, Chizzonite R, Desai BB, et al. Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130. J Immunol 1994;153:128-36.
The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies
Airoldi I, Di Carlo E, Banelli B, et al. The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies. J Clin Invest 2004;113:1651-9.
Lack of IL-12R{beta}2 signalling predisposes to spontaneous autoimmunity and malignancy
Airoldi I, Di Carlo E, Cocco C, et al. Lack of IL-12R{beta}2 signalling predisposes to spontaneous autoimmunity and malignancy. Blood 2005;106:3846-53.
Analysis of mammary carcinoma onset and progression in HER-2/neu oncogene transgenic mice reveals a lobular origin
Di Carlo E, Diodoro MG, Boggio K, et al. Analysis of mammary carcinoma onset and progression in HER-2/neu oncogene transgenic mice reveals a lobular origin. Lab Invest 1999;79:1261-9.
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
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Herman JG, Graff JR, Myohanen S, et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996;93:9821-6.
In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment
Durali D, de Goer de Herve MG, Giron-Michel J, et al. In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment. Blood 2003;102:4084-9.
