메뉴 건너뛰기




Volumn 23, Issue 17, 2005, Pages 3886-3896

Epigenetic profiling of cutaneous T-cell lymphoma: Promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P15; PROTEIN P16; PROTEIN P73; THROMBOSPONDIN; ACTIN BINDING PROTEIN; BCL7A PROTEIN, HUMAN; CD30 ANTIGEN; DNA; DNA BINDING PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; PROTEIN TYROSINE PHOSPHATASE; RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA; THROMBOSPONDIN 4; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

EID: 21244458051     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.11.353     Document Type: Article
Times cited : (207)

References (56)
  • 1
    • 0031007614 scopus 로고    scopus 로고
    • EORTC classification for primary cutaneous lymphomas: A proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer
    • Willemze R, Kerl H, Sterry W, et al: EORTC classification for primary cutaneous lymphomas: A proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer. Blood 90:354-371, 1997
    • (1997) Blood , vol.90 , pp. 354-371
    • Willemze, R.1    Kerl, H.2    Sterry, W.3
  • 2
    • 0036791130 scopus 로고    scopus 로고
    • A novel splice variant of the Fas gene in patients with cutaneous T-cell lymphoma
    • van Doom R, Dijkman R, Vermeer MH, et al: A novel splice variant of the Fas gene in patients with cutaneous T-cell lymphoma. Cancer Res 62:5389-5392, 2002
    • (2002) Cancer Res , vol.62 , pp. 5389-5392
    • van Doom, R.1    Dijkman, R.2    Vermeer, M.H.3
  • 3
    • 0029015704 scopus 로고
    • Reduced surface expression of transforming growth factor beta receptor type II in mitogen-activated T cells from Sezary patients
    • Capocasale RJ, Lamb RJ, Vonderheid EC, et al: Reduced surface expression of transforming growth factor beta receptor type II in mitogen-activated T cells from Sezary patients. Proc Natl Acad Sci U S A 92:5501-5505, 1995
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5501-5505
    • Capocasale, R.J.1    Lamb, R.J.2    Vonderheid, E.C.3
  • 4
    • 3142735120 scopus 로고    scopus 로고
    • In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3
    • Sommer VH, Clemmensen OJ, Nielsen O, et al: In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3. Leukemia 18:1288-1295, 2004
    • (2004) Leukemia , vol.18 , pp. 1288-1295
    • Sommer, V.H.1    Clemmensen, O.J.2    Nielsen, O.3
  • 6
    • 0033843331 scopus 로고    scopus 로고
    • p16(INK4a) gene alterations are frequent in lesions of mycosis fungoides
    • Navas IC, Ortiz-Romero PL, Villuendas R, et al: p16(INK4a) gene alterations are frequent in lesions of mycosis fungoides. Am J Pathol 156:1565-1572, 2000
    • (2000) Am J Pathol , vol.156 , pp. 1565-1572
    • Navas, I.C.1    Ortiz-Romero, P.L.2    Villuendas, R.3
  • 7
    • 0036121141 scopus 로고    scopus 로고
    • Frequent abnormalities of the p15 and p16 genes in mycosis fungoides and Sezary syndrome
    • Scarisbrick JJ, Woolford AJ, Calonje E, et al: Frequent abnormalities of the p15 and p16 genes in mycosis fungoides and Sezary syndrome. J Invest Dermatol 118:493-499, 2002
    • (2002) J Invest Dermatol , vol.118 , pp. 493-499
    • Scarisbrick, J.J.1    Woolford, A.J.2    Calonje, E.3
  • 8
    • 0033809993 scopus 로고    scopus 로고
    • Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter
    • Zhang Q, Raghunath PN, Vonderheid E, et al: Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter. Am J Pathol 157:1137-1146, 2000
    • (2000) Am J Pathol , vol.157 , pp. 1137-1146
    • Zhang, Q.1    Raghunath, P.N.2    Vonderheid, E.3
  • 9
    • 0141922001 scopus 로고    scopus 로고
    • Microsatellite instability is associated with hypermethylation of the hMLH1 gene and reduced gene expression in mycosis fungoides
    • Scarisbrick JJ, Mitchell TJ, Calonje E, et al: Microsatellite instability is associated with hypermethylation of the hMLH1 gene and reduced gene expression in mycosis fungoides. J Invest Dermatol 121:894-901, 2003
    • (2003) J Invest Dermatol , vol.121 , pp. 894-901
    • Scarisbrick, J.J.1    Mitchell, T.J.2    Calonje, E.3
  • 10
    • 16544389958 scopus 로고    scopus 로고
    • Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor
    • Deng G, Song GA, Pong E, et al: Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor. Cancer Res 64: 2692-2698, 2004
    • (2004) Cancer Res , vol.64 , pp. 2692-2698
    • Deng, G.1    Song, G.A.2    Pong, E.3
  • 11
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB: Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349:2042-2054, 2003
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 12
    • 0343621494 scopus 로고    scopus 로고
    • Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
    • Costello JF, Fruhwald MC, Smiraglia DJ, et al: Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 24:132-138, 2000
    • (2000) Nat Genet , vol.24 , pp. 132-138
    • Costello, J.F.1    Fruhwald, M.C.2    Smiraglia, D.J.3
  • 13
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • Esteller M, Corn PG, Baylin SB, et al: A gene hypermethylation profile of human cancer. Cancer Res 61:3225-3229, 2001
    • (2001) Cancer Res , vol.61 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3
  • 14
    • 0038576158 scopus 로고    scopus 로고
    • The power and the promise of DNA methylation markers
    • Laird PW: The power and the promise of DNA methylation markers. Nat Rev Cancer 3: 253-266, 2003
    • (2003) Nat Rev Cancer , vol.3 , pp. 253-266
    • Laird, P.W.1
  • 15
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger G, Liang G, Aparicio A, et al: Epigenetics in human disease and prospects for epigenetic therapy. Nature 429:457-463, 2004
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3
  • 16
    • 0035525781 scopus 로고    scopus 로고
    • Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T cell lymphoma: A case report
    • Piekarz RL, Robey R, Sandor V, et al: Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T cell lymphoma: A case report. Blood 98:2865-2868, 2001
    • (2001) Blood , vol.98 , pp. 2865-2868
    • Piekarz, R.L.1    Robey, R.2    Sandor, V.3
  • 17
    • 0142153982 scopus 로고    scopus 로고
    • Profiling aberrant DNA methylation in hematologic neoplasms: A view from the tip of the iceberg
    • Esteller M: Profiling aberrant DNA methylation in hematologic neoplasms: A view from the tip of the iceberg. Clin Immunol 109:80-88, 2003
    • (2003) Clin Immunol , vol.109 , pp. 80-88
    • Esteller, M.1
  • 18
    • 2442577021 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation
    • Kondo Y, Shen L, Yan PS, et al: Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Proc Natl Acad Sci U S A 101:7398-7403, 2004
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 7398-7403
    • Kondo, Y.1    Shen, L.2    Yan, P.S.3
  • 19
    • 0036322489 scopus 로고    scopus 로고
    • Applications of CpG island microarrays for high-throughput analysis of DNA methylation
    • suppl
    • Yan PS, Chen CM, Shi H, et al: Applications of CpG island microarrays for high-throughput analysis of DNA methylation. J Nutr 132:24305-24345, 2002 (suppl)
    • (2002) J Nutr , vol.132 , pp. 24305-24345
    • Yan, P.S.1    Chen, C.M.2    Shi, H.3
  • 20
    • 0036318071 scopus 로고    scopus 로고
    • Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation
    • Yan PS, Efferth T, Chen HL, et al: Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation. Methods 27:162-169, 2002
    • (2002) Methods , vol.27 , pp. 162-169
    • Yan, P.S.1    Efferth, T.2    Chen, H.L.3
  • 21
    • 12944314959 scopus 로고    scopus 로고
    • Transformation of mycosis fungoides: Clinicopathological and prognostic features of 45 cases. French Study Group of Cutaneious Lymphomas
    • Vergier B, de Muret A, Beylot-Barry M, et al: Transformation of mycosis fungoides: clinicopathological and prognostic features of 45 cases. French Study Group of Cutaneious Lymphomas. Blood 95:2212-2218, 2000
    • (2000) Blood , vol.95 , pp. 2212-2218
    • Vergier, B.1    de Muret, A.2    Beylot-Barry, M.3
  • 22
    • 0034660654 scopus 로고    scopus 로고
    • Primary and secondary cutaneous CD30(+) lymphoproliferative disorders: A report from the Dutch Cutaneous Lymphoma Group on the long-term follow-up data of 219 patients and guidelines for diagnosis and treatment
    • Bekkenk MW, Geelen FA, van Voorst Vader PC, et al: Primary and secondary cutaneous CD30(+) lymphoproliferative disorders: A report from the Dutch Cutaneous Lymphoma Group on the long-term follow-up data of 219 patients and guidelines for diagnosis and treatment. Blood 95:3653-3661, 2000
    • (2000) Blood , vol.95 , pp. 3653-3661
    • Bekkenk, M.W.1    Geelen, F.A.2    van Voorst Vader, P.C.3
  • 23
    • 11244346557 scopus 로고    scopus 로고
    • Variance stabilization applied to microarray data calibration and to the quantification of differential expression
    • suppl
    • Huber W, von Heydebreck A, Sultmann H, et al: Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 18:S96-104, 2002 (suppl)
    • (2002) Bioinformatics , vol.18
    • Huber, W.1    von Heydebreck, A.2    Sultmann, H.3
  • 24
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y: Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Statist Soc B 57:289-300, 1995
    • (1995) J R Statist Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 25
    • 0035353188 scopus 로고    scopus 로고
    • Methylation profiling in acute myeloid leukemia
    • Toyota M, Kopecky KJ, Toyota MO, et al: Methylation profiling in acute myeloid leukemia. Blood 97:2823-2829, 2001
    • (2001) Blood , vol.97 , pp. 2823-2829
    • Toyota, M.1    Kopecky, K.J.2    Toyota, M.O.3
  • 26
    • 0035992430 scopus 로고    scopus 로고
    • DNA methylation of multiple promoter-associated CpG islands in adult acute lymphocytic leukemia
    • Garcia-Manero G, Daniel J, Smith TL, et al: DNA methylation of multiple promoter-associated CpG islands in adult acute lymphocytic leukemia. Clin Cancer Res 8:2217-2224, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 2217-2224
    • Garcia-Manero, G.1    Daniel, J.2    Smith, T.L.3
  • 27
    • 0026721931 scopus 로고
    • Establishment of two continuous T-cell strains from a single plaque of a patient with mycosis fungoides
    • 3pt 1
    • Kaltoft K, Bisballe S, Dyrberg T, et al: Establishment of two continuous T-cell strains from a single plaque of a patient with mycosis fungoides. In Vitro Cell Dev Biol 28A:161-167, 1992 (3pt 1)
    • (1992) In Vitro Cell Dev Biol , vol.28 A , pp. 161-167
    • Kaltoft, K.1    Bisballe, S.2    Dyrberg, T.3
  • 28
    • 0035577862 scopus 로고    scopus 로고
    • Dissecting complex epigenetic alterations in breast cancer using CpG island microarrays
    • Yan PS, Chen CM, Shi H, et al: Dissecting complex epigenetic alterations in breast cancer using CpG island microarrays. Cancer Res 61: 8375-8380, 2001
    • (2001) Cancer Res , vol.61 , pp. 8375-8380
    • Yan, P.S.1    Chen, C.M.2    Shi, H.3
  • 29
    • 0035992386 scopus 로고    scopus 로고
    • Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers
    • Wei SH, Chen CM, Strathdee G, et al: Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers. Clin Cancer Res 8:2246-2252, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 2246-2252
    • Wei, S.H.1    Chen, C.M.2    Strathdee, G.3
  • 30
    • 0033529309 scopus 로고    scopus 로고
    • Analysis of human peripheral blood T cells and single-cell-derived T cell clones uncovers extensive clonal CpG island methylation heterogeneity throughout the genome
    • Zhu X, Deng C, Kuick R, et al: Analysis of human peripheral blood T cells and single-cell-derived T cell clones uncovers extensive clonal CpG island methylation heterogeneity throughout the genome. Proc Natl Acad Sci U S A 96:8058-8063, 1999
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 8058-8063
    • Zhu, X.1    Deng, C.2    Kuick, R.3
  • 31
    • 0035874532 scopus 로고    scopus 로고
    • Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci
    • Rush LJ, Dai Z, Smiraglia DJ, et al: Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci. Blood 97:3226-3233, 2001
    • (2001) Blood , vol.97 , pp. 3226-3233
    • Rush, L.J.1    Dai, Z.2    Smiraglia, D.J.3
  • 32
    • 0037447149 scopus 로고    scopus 로고
    • DNA hypermethylation near the transcription start site of collagen alpha2(I) gene occurs in both cancer cell lines and primary colorectal cancers
    • Sengupta PK, Smith EM, Kim K, et al: DNA hypermethylation near the transcription start site of collagen alpha2(I) gene occurs in both cancer cell lines and primary colorectal cancers. Cancer Res 63:1789-1797, 2003
    • (2003) Cancer Res , vol.63 , pp. 1789-1797
    • Sengupta, P.K.1    Smith, E.M.2    Kim, K.3
  • 33
    • 0036753290 scopus 로고    scopus 로고
    • Fraga MF, Esteller M: DNA methylation: A profile of methods and applications. Biotechniques 33:632,634,636-49, 2002
    • Fraga MF, Esteller M: DNA methylation: A profile of methods and applications. Biotechniques 33:632,634,636-49, 2002
  • 34
    • 0033179665 scopus 로고    scopus 로고
    • Loss of p73 gene expression in leukemias/ lymphomas due to hypermethylation
    • Kawano S, Miller CW, Gombart AF, et al: Loss of p73 gene expression in leukemias/ lymphomas due to hypermethylation. Blood 94:1113-1120, 1999
    • (1999) Blood , vol.94 , pp. 1113-1120
    • Kawano, S.1    Miller, C.W.2    Gombart, A.F.3
  • 35
    • 0037005988 scopus 로고    scopus 로고
    • Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma
    • Esteller M, Gaidano G, Goodman SN, et al: Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J Natl Cancer Inst 94:26-32, 2002
    • (2002) J Natl Cancer Inst , vol.94 , pp. 26-32
    • Esteller, M.1    Gaidano, G.2    Goodman, S.N.3
  • 36
    • 1242307338 scopus 로고    scopus 로고
    • SOCS1 and SHP1 hypermethylation in mantle cell lymphoma and follicular lymphoma: Implications for epigenetic activation of the Jak/STAT pathway
    • Chim CS, Wong KY, Loong F, et al: SOCS1 and SHP1 hypermethylation in mantle cell lymphoma and follicular lymphoma: Implications for epigenetic activation of the Jak/STAT pathway. Leukemia 18:356-358, 2004
    • (2004) Leukemia , vol.18 , pp. 356-358
    • Chim, C.S.1    Wong, K.Y.2    Loong, F.3
  • 37
    • 0033676843 scopus 로고    scopus 로고
    • TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers
    • Conway KE, McConnell BB, Bowring CE, et al: TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers. Cancer Res 60:6236-6242, 2000
    • (2000) Cancer Res , vol.60 , pp. 6236-6242
    • Conway, K.E.1    McConnell, B.B.2    Bowring, C.E.3
  • 38
    • 0037934421 scopus 로고    scopus 로고
    • Epigenetic inactivation of CHFR in human tumors
    • Toyota M, Sasaki Y, Satoh A, et al: Epigenetic inactivation of CHFR in human tumors. Proc Natl Acad Sci U S A 100:7818-7823, 2003
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7818-7823
    • Toyota, M.1    Sasaki, Y.2    Satoh, A.3
  • 39
    • 4944236206 scopus 로고    scopus 로고
    • Promoter hypermethylation of cancer-related genes: A strong independent prognostic factor in acute lymphoblastic leukemia
    • Roman-Gomez J, Jimenez-Velasco A, Castillejo JA, et al: Promoter hypermethylation of cancer-related genes: A strong independent prognostic factor in acute lymphoblastic leukemia. Blood 104:2492-2498, 2004
    • (2004) Blood , vol.104 , pp. 2492-2498
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Castillejo, J.A.3
  • 40
    • 0029867126 scopus 로고    scopus 로고
    • Zani VJ, Asou N, Jadayel D, et al: Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon. Blood 87:3124-3134, 1996
    • Zani VJ, Asou N, Jadayel D, et al: Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon. Blood 87:3124-3134, 1996
  • 41
    • 0042744782 scopus 로고    scopus 로고
    • Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: An expression profile study
    • Tracey L, Villuendas R, Dotor AM, et al: Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: An expression profile study. Blood 102:1042-1050, 2003
    • (2003) Blood , vol.102 , pp. 1042-1050
    • Tracey, L.1    Villuendas, R.2    Dotor, A.M.3
  • 42
    • 4143126609 scopus 로고    scopus 로고
    • Expression profiling of T-cell lymphomas differentiates peripheral and lymphoblastic lymphomas and defines survival related genes
    • Martinez-Delgado B, Melendez B, Cuadros M, et al: Expression profiling of T-cell lymphomas differentiates peripheral and lymphoblastic lymphomas and defines survival related genes. Clin Cancer Res 10:4971-4982, 2004
    • (2004) Clin Cancer Res , vol.10 , pp. 4971-4982
    • Martinez-Delgado, B.1    Melendez, B.2    Cuadros, M.3
  • 43
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al: Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403:503-511, 2000
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 44
    • 0142135512 scopus 로고    scopus 로고
    • Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas
    • Motiwala T, Ghoshal K, Das A, et al: Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas. Oncogene 22:6319-6331, 2003
    • (2003) Oncogene , vol.22 , pp. 6319-6331
    • Motiwala, T.1    Ghoshal, K.2    Das, A.3
  • 45
    • 2442648882 scopus 로고    scopus 로고
    • Mutational analysis of the tyrosine phosphatome in colorectal cancers
    • Wang Z, Shen D, Parsons DW, et al: Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 304:1164-1166, 2004
    • (2004) Science , vol.304 , pp. 1164-1166
    • Wang, Z.1    Shen, D.2    Parsons, D.W.3
  • 46
    • 0025757145 scopus 로고
    • Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21
    • LaForgia S, Morse B, Levy J, et al: Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21. Proc Natl Acad Sci USA 88:5036-5040, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5036-5040
    • LaForgia, S.1    Morse, B.2    Levy, J.3
  • 47
    • 0030812206 scopus 로고    scopus 로고
    • Association between CpG island methylation and microsatellite instability in colorectal cancer
    • Ahuja N, Mohan AL, Li Q, et al: Association between CpG island methylation and microsatellite instability in colorectal cancer. Cancer Res 57:3370-3374, 1997
    • (1997) Cancer Res , vol.57 , pp. 3370-3374
    • Ahuja, N.1    Mohan, A.L.2    Li, Q.3
  • 48
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • Esteller M, Garcia-Foncillas J, Andion E, et al: Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343:1350-1354, 2000
    • (2000) N Engl J Med , vol.343 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3
  • 49
    • 2942572047 scopus 로고    scopus 로고
    • Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia
    • Rossi D, Capello D, Gloghini A, et al: Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia. Haematologica 89:154-164, 2004
    • (2004) Haematologica , vol.89 , pp. 154-164
    • Rossi, D.1    Capello, D.2    Gloghini, A.3
  • 50
    • 0344844471 scopus 로고    scopus 로고
    • Death-associated protein kinase promoter hypermethylation in normal human lymphocytes
    • Reddy AN, Jiang WW, Kim M, et al: Death-associated protein kinase promoter hypermethylation in normal human lymphocytes. Cancer Res 63:7694-7698, 2003
    • (2003) Cancer Res , vol.63 , pp. 7694-7698
    • Reddy, A.N.1    Jiang, W.W.2    Kim, M.3
  • 51
    • 0034609864 scopus 로고    scopus 로고
    • A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
    • Lissy NA, Davis PK, Irwin M, et al: A common E2F-1 and p73 pathway mediates cell death induced by TCR activation. Nature 407:642-645, 2000
    • (2000) Nature , vol.407 , pp. 642-645
    • Lissy, N.A.1    Davis, P.K.2    Irwin, M.3
  • 52
    • 0036837257 scopus 로고    scopus 로고
    • Frequent inactivation of the p73 gene by abnormal methylation or LOH in non-Hodgkin's lymphomas
    • Martinez-Delgado B, Melendez B, Cuadros M, et al: Frequent inactivation of the p73 gene by abnormal methylation or LOH in non-Hodgkin's lymphomas. Int J Cancer 102:15-19, 2002
    • (2002) Int J Cancer , vol.102 , pp. 15-19
    • Martinez-Delgado, B.1    Melendez, B.2    Cuadros, M.3
  • 53
    • 0038683899 scopus 로고    scopus 로고
    • Aberrant promoter CpG methylation as a molecular marker for disease monitoring in natural killer cell lymphomas
    • Siu LL, Chan JK, Wong KF, et al: Aberrant promoter CpG methylation as a molecular marker for disease monitoring in natural killer cell lymphomas. Br J Haematol 122:70-77, 2003
    • (2003) Br J Haematol , vol.122 , pp. 70-77
    • Siu, L.L.1    Chan, J.K.2    Wong, K.F.3
  • 54
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′- deoxycytidine (decitabine) in hematopoietic malignancies
    • Issa JP, Garcia-Manero G, Giles FJ, et al: Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′- deoxycytidine (decitabine) in hematopoietic malignancies. Blood 103:1635-1640, 2004
    • (2004) Blood , vol.103 , pp. 1635-1640
    • Issa, J.P.1    Garcia-Manero, G.2    Giles, F.J.3
  • 55
    • 5144228492 scopus 로고    scopus 로고
    • Preferential response of cancer cells to zebularine
    • Cheng JC, Yoo CB, Weisenberger DJ, et al: Preferential response of cancer cells to zebularine. Cancer Cell 6:151-158, 2004
    • (2004) Cancer Cell , vol.6 , pp. 151-158
    • Cheng, J.C.1    Yoo, C.B.2    Weisenberger, D.J.3
  • 56
    • 12444297637 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks
    • Davis AJ, Gelmon KA, Siu LL, et al: Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks. Invest New Drugs 21:85-97, 2003
    • (2003) Invest New Drugs , vol.21 , pp. 85-97
    • Davis, A.J.1    Gelmon, K.A.2    Siu, L.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.