Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points

American Journal of Surgical Pathology

Volumn 30, Issue 12, 2006, Pages 1491-1501

  O'Brien, Michael J ^a,b   Yang, Shi ^a   Mack, Charline ^a   Xu, Huihong ^a   Huang, Christopher S ^a   Mulcahy, Elizabeth ^a   Amorosino, Mark ^a   Farraye, Francis A ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^b BOSTON MEDICAL CENTER   (United States)

Author keywords

BRAF; CIMP; Colorectal carcinomas; KRAS; MSI; Serrated polyps

Indexed keywords

DNA;

ADVANCED CANCER; ARTICLE; BAT25 GENE; BAT26 GENE; BRAF GENE; CANCER GROWTH; CANCER STAGING; CELL PROLIFERATION; CODON; COLON ADENOCARCINOMA; COLON ADENOMA; COLON CARCINOMA; COLON POLYP; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; DISEASE COURSE; DNA DETERMINATION; DNA EXTRACTION; DNA METHYLATION; DNA SEQUENCE; GENE; GENE MUTATION; GENE SEQUENCE; GENOTYPE PHENOTYPE CORRELATION; GOBLET CELL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KRAS2 GENE; MARKER GENE; MGMT GENE; MICROSATELLITE INSTABILITY; MINT1 GENE; MINT2 GENE; MLH1 GENE; MSI GENE; MUTATION RATE; ONCOGENE; ONCOGENE K RAS; PHENOTYPE; RECTUM ADENOMA; SEQUENCE ANALYSIS; SERRATED POLYP; TUMOR DIAGNOSIS; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; TUMOR VOLUME;

ADENOCARCINOMA; ADENOMA; AGED; COLONIC POLYPS; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; DNA, NEOPLASM; FEMALE; GENETIC MARKERS; HUMANS; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; PHENOTYPE; PRECANCEROUS CONDITIONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 33751320353     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000213313.36306.85     Document Type: Article

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