Zebularine: A unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology

Nucleosides, Nucleotides and Nucleic Acids

Volumn 24, Issue 5-7, 2005, Pages 305-318

  Marquez, Victor E ^a   Barchi Jr , Joseph J ^a   Kelley, James A ^a   Rao, Kambhampati V R ^b   Agbaria, Riad ^c   Ben Kasus, Tsipi ^c   Cheng, Jonathan C ^d   Yoo, Christine B ^d   Jones, Peter A ^d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Antitumor Activity; Cytidine Deaminase Inhibition; DNA Methyltrasferase Inhibition; Isouridine; Ring Expanded Nucleoside Analogues; Zebularine

Indexed keywords

4 DEAMINOCYTIDINE; ANTINEOPLASTIC AGENT; CYTIDINE DEAMINASE INHIBITOR; CYTIDINE DERIVATIVE; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA METHYLTRANSFERASE; ISOURIDINE; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG; URIDINE DERIVATIVE; ZEBULARINE;

CANCER CHEMOTHERAPY; CONFERENCE PAPER; DRUG STABILITY; DRUG STRUCTURE; EPIGENETICS; HUMAN; IN VITRO STUDY; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; TARGET CELL;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; CYTIDINE; CYTIDINE DEAMINASE; DNA; EPIGENESIS, GENETIC; HUMANS; MODELS, CHEMICAL; NEOPLASMS;

ANIMALIA;

EID: 26644460450     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1081/NCN-200059765     Document Type: Conference Paper

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