-
1
-
-
0032525981
-
Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
-
U. Ahlgren, J. Jonsson, L. Jonsson, K. Simu, and H. Edlund beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes Genes Dev. 12 1998 1763 1768
-
(1998)
Genes Dev.
, vol.12
, pp. 1763-1768
-
-
Ahlgren, U.1
Jonsson, J.2
Jonsson, L.3
Simu, K.4
Edlund, H.5
-
2
-
-
84876351067
-
Gene regulatory networks governing pancreas development
-
H.E. Arda, C.M. Benitez, and S.K. Kim Gene regulatory networks governing pancreas development Dev. Cell 25 2013 5 13
-
(2013)
Dev. Cell
, vol.25
, pp. 5-13
-
-
Arda, H.E.1
Benitez, C.M.2
Kim, S.K.3
-
3
-
-
12944327377
-
In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells
-
L. Baeyens, S. De Breuck, J. Lardon, J.K. Mfopou, I. Rooman, and L. Bouwens In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells Diabetologia 48 2005 49 57
-
(2005)
Diabetologia
, vol.48
, pp. 49-57
-
-
Baeyens, L.1
De Breuck, S.2
Lardon, J.3
Mfopou, J.K.4
Rooman, I.5
Bouwens, L.6
-
4
-
-
33749590993
-
Ngn3 expression during postnatal in vitro beta cell neogenesis induced by the JAK/STAT pathway
-
L. Baeyens, S. Bonné, M.S. German, P. Ravassard, H. Heimberg, and L. Bouwens Ngn3 expression during postnatal in vitro beta cell neogenesis induced by the JAK/STAT pathway Cell Death Differ. 13 2006 1892 1899
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1892-1899
-
-
Baeyens, L.1
Bonné, S.2
German, M.S.3
Ravassard, P.4
Heimberg, H.5
Bouwens, L.6
-
5
-
-
65249128642
-
Notch signaling as gatekeeper of rat acinar-to-beta-cell conversion in vitro
-
e1713
-
L. Baeyens, S. Bonne, T. Bos, I. Rooman, C. Peleman, T. Lahoutte, M. German, H. Heimberg, and L. Bouwens Notch signaling as gatekeeper of rat acinar-to-beta-cell conversion in vitro Gastroenterology 136 2009 1750 1760 e1713
-
(2009)
Gastroenterology
, vol.136
, pp. 1750-1760
-
-
Baeyens, L.1
Bonne, S.2
Bos, T.3
Rooman, I.4
Peleman, C.5
Lahoutte, T.6
German, M.7
Heimberg, H.8
Bouwens, L.9
-
6
-
-
84892173922
-
Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
-
L. Baeyens, M. Lemper, G. Leuckx, S. De Groef, P. Bonfanti, G. Stangé, R. Shemer, C. Nord, D.W. Scheel, and F.C. Pan Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice Nat. Biotechnol. 32 2014 76 83
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 76-83
-
-
Baeyens, L.1
Lemper, M.2
Leuckx, G.3
De Groef, S.4
Bonfanti, P.5
Stangé, G.6
Shemer, R.7
Nord, C.8
Scheel, D.W.9
Pan, F.C.10
-
8
-
-
33645236232
-
PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L
-
T.M. Beres, T. Masui, G.H. Swift, L. Shi, R.M. Henke, and R.J. MacDonald PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L Mol. Cell. Biol. 26 2006 117 130
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 117-130
-
-
Beres, T.M.1
Masui, T.2
Swift, G.H.3
Shi, L.4
Henke, R.M.5
Macdonald, R.J.6
-
9
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
B.E. Bernstein, T.S. Mikkelsen, X. Xie, M. Kamal, D.J. Huebert, J. Cuff, B. Fry, A. Meissner, M. Wernig, and K. Plath A bivalent chromatin structure marks key developmental genes in embryonic stem cells Cell 125 2006 315 326
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
10
-
-
0042440941
-
Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice
-
P. Bertolino, W.M. Tong, P.L. Herrera, H. Casse, C.X. Zhang, and Z.Q. Wang Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice Cancer Res. 63 2003 4836 4841
-
(2003)
Cancer Res.
, vol.63
, pp. 4836-4841
-
-
Bertolino, P.1
Tong, W.M.2
Herrera, P.L.3
Casse, H.4
Zhang, C.X.5
Wang, Z.Q.6
-
11
-
-
85003341559
-
Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway
-
B. Blum, A.N. Roose, O. Barrandon, R. Maehr, A.C. Arvanites, L.S. Davidow, J.C. Davis, Q.P. Peterson, L.L. Rubin, and D.A. Melton Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway eLife 3 2014 10.7554/eLife.02809
-
(2014)
ELife
, vol.3
-
-
Blum, B.1
Roose, A.N.2
Barrandon, O.3
Maehr, R.4
Arvanites, A.C.5
Davidow, L.S.6
Davis, J.C.7
Peterson, Q.P.8
Rubin, L.L.9
Melton, D.A.10
-
12
-
-
59849105832
-
Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice
-
e309
-
C. Bonal, F. Thorel, A. Ait-Lounis, W. Reith, A. Trumpp, and P.L. Herrera Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice Gastroenterology 136 2009 309 319 e309
-
(2009)
Gastroenterology
, vol.136
, pp. 309-319
-
-
Bonal, C.1
Thorel, F.2
Ait-Lounis, A.3
Reith, W.4
Trumpp, A.5
Herrera, P.L.6
-
13
-
-
84874626174
-
Epigenomic plasticity enables human pancreatic α to β cell reprogramming
-
N.C. Bramswig, L.J. Everett, J. Schug, C. Dorrell, C. Liu, Y. Luo, P.R. Streeter, A. Naji, M. Grompe, and K.H. Kaestner Epigenomic plasticity enables human pancreatic α to β cell reprogramming J. Clin. Invest. 123 2013 1275 1284
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 1275-1284
-
-
Bramswig, N.C.1
Everett, L.J.2
Schug, J.3
Dorrell, C.4
Liu, C.5
Luo, Y.6
Streeter, P.R.7
Naji, A.8
Grompe, M.9
Kaestner, K.H.10
-
14
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
A.E. Butler, J. Janson, S. Bonner-Weir, R. Ritzel, R.A. Rizza, and P.C. Butler Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes Diabetes 52 2003 102 110
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
15
-
-
34248372925
-
The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia
-
C. Carrière, E.S. Seeley, T. Goetze, D.S. Longnecker, and M. Korc The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia Proc. Natl. Acad. Sci. USA 104 2007 4437 4442
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4437-4442
-
-
Carrière, C.1
Seeley, E.S.2
Goetze, T.3
Longnecker, D.S.4
Korc, M.5
-
16
-
-
84920744392
-
Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers
-
S. Chera, D. Baronnier, L. Ghila, V. Cigliola, J.N. Jensen, G. Gu, K. Furuyama, F. Thorel, F.M. Gribble, F. Reimann, and P.L. Herrera Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers Nature 514 2014 503 507
-
(2014)
Nature
, vol.514
, pp. 503-507
-
-
Chera, S.1
Baronnier, D.2
Ghila, L.3
Cigliola, V.4
Jensen, J.N.5
Gu, G.6
Furuyama, K.7
Thorel, F.8
Gribble, F.M.9
Reimann, F.10
Herrera, P.L.11
-
17
-
-
84858390754
-
Reprogramming cellular identity for regenerative medicine
-
A.B. Cherry, and G.Q. Daley Reprogramming cellular identity for regenerative medicine Cell 148 2012 1110 1122
-
(2012)
Cell
, vol.148
, pp. 1110-1122
-
-
Cherry, A.B.1
Daley, G.Q.2
-
18
-
-
84865158307
-
Exocrine ontogenies: On the development of pancreatic acinar, ductal and centroacinar cells
-
M.H. Cleveland, J.M. Sawyer, S. Afelik, J. Jensen, and S.D. Leach Exocrine ontogenies: on the development of pancreatic acinar, ductal and centroacinar cells Semin. Cell Dev. Biol. 23 2012 711 719
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 711-719
-
-
Cleveland, M.H.1
Sawyer, J.M.2
Afelik, S.3
Jensen, J.4
Leach, S.D.5
-
19
-
-
79952900560
-
Turning straw into gold: Directing cell fate for regenerative medicine
-
D.E. Cohen, and D. Melton Turning straw into gold: directing cell fate for regenerative medicine Nat. Rev. Genet. 12 2011 243 252
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 243-252
-
-
Cohen, D.E.1
Melton, D.2
-
20
-
-
84863012865
-
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
-
M.A. Collins, F. Bednar, Y. Zhang, J.C. Brisset, S. Galbán, C.J. Galbán, S. Rakshit, K.S. Flannagan, N.V. Adsay, and M. Pasca di Magliano Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice J. Clin. Invest. 122 2012 639 653
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 639-653
-
-
Collins, M.A.1
Bednar, F.2
Zhang, Y.3
Brisset, J.C.4
Galbán, S.5
Galbán, C.J.6
Rakshit, S.7
Flannagan, K.S.8
Adsay, N.V.9
Pasca Di Magliano, M.10
-
21
-
-
0142091542
-
Opposing actions of Arx and Pax4 in endocrine pancreas development
-
P. Collombat, A. Mansouri, J. Hecksher-Sorensen, P. Serup, J. Krull, G. Gradwohl, and P. Gruss Opposing actions of Arx and Pax4 in endocrine pancreas development Genes Dev. 17 2003 2591 2603
-
(2003)
Genes Dev.
, vol.17
, pp. 2591-2603
-
-
Collombat, P.1
Mansouri, A.2
Hecksher-Sorensen, J.3
Serup, P.4
Krull, J.5
Gradwohl, G.6
Gruss, P.7
-
22
-
-
23144432613
-
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas
-
P. Collombat, J. Hecksher-Sørensen, V. Broccoli, J. Krull, I. Ponte, T. Mundiger, J. Smith, P. Gruss, P. Serup, and A. Mansouri The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas Development 132 2005 2969 2980
-
(2005)
Development
, vol.132
, pp. 2969-2980
-
-
Collombat, P.1
Hecksher-Sørensen, J.2
Broccoli, V.3
Krull, J.4
Ponte, I.5
Mundiger, T.6
Smith, J.7
Gruss, P.8
Serup, P.9
Mansouri, A.10
-
23
-
-
34147092649
-
Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression
-
P. Collombat, J. Hecksher-Sørensen, J. Krull, J. Berger, D. Riedel, P.L. Herrera, P. Serup, and A. Mansouri Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression J. Clin. Invest. 117 2007 961 970
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 961-970
-
-
Collombat, P.1
Hecksher-Sørensen, J.2
Krull, J.3
Berger, J.4
Riedel, D.5
Herrera, P.L.6
Serup, P.7
Mansouri, A.8
-
24
-
-
68149162957
-
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells
-
P. Collombat, X. Xu, P. Ravassard, B. Sosa-Pineda, S. Dussaud, N. Billestrup, O.D. Madsen, P. Serup, H. Heimberg, and A. Mansouri The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells Cell 138 2009 449 462
-
(2009)
Cell
, vol.138
, pp. 449-462
-
-
Collombat, P.1
Xu, X.2
Ravassard, P.3
Sosa-Pineda, B.4
Dussaud, S.5
Billestrup, N.6
Madsen, O.D.7
Serup, P.8
Heimberg, H.9
Mansouri, A.10
-
25
-
-
84887311096
-
The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells
-
M. Courtney, E. Gjernes, N. Druelle, C. Ravaud, A. Vieira, N. Ben-Othman, A. Pfeifer, F. Avolio, G. Leuckx, and S. Lacas-Gervais The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells PLoS Genet. 9 2013 e1003934
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003934
-
-
Courtney, M.1
Gjernes, E.2
Druelle, N.3
Ravaud, C.4
Vieira, A.5
Ben-Othman, N.6
Pfeifer, A.7
Avolio, F.8
Leuckx, G.9
Lacas-Gervais, S.10
-
26
-
-
57749116315
-
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
-
J.P. De La O, L.L. Emerson, J.L. Goodman, S.C. Froebe, B.E. Illum, A.B. Curtis, and L.C. Murtaugh Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia Proc. Natl. Acad. Sci. USA 105 2008 18907 18912
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18907-18912
-
-
De La O, J.P.1
Emerson, L.L.2
Goodman, J.L.3
Froebe, S.C.4
Illum, B.E.5
Curtis, A.B.6
Murtaugh, L.C.7
-
27
-
-
84864029149
-
Sox9b is a key regulator of pancreaticobiliary ductal system development
-
M. Delous, C. Yin, D. Shin, N. Ninov, J. Debrito Carten, L. Pan, T.P. Ma, S.A. Farber, C.B. Moens, and D.Y. Stainier Sox9b is a key regulator of pancreaticobiliary ductal system development PLoS Genet. 8 2012 e1002754
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002754
-
-
Delous, M.1
Yin, C.2
Shin, D.3
Ninov, N.4
Debrito Carten, J.5
Pan, L.6
Ma, T.P.7
Farber, S.A.8
Moens, C.B.9
Stainier, D.Y.10
-
28
-
-
34147190365
-
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration
-
B.M. Desai, J. Oliver-Krasinski, D.D. De Leon, C. Farzad, N. Hong, S.D. Leach, and D.A. Stoffers Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration J. Clin. Invest. 117 2007 971 977
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 971-977
-
-
Desai, B.M.1
Oliver-Krasinski, J.2
De Leon, D.D.3
Farzad, C.4
Hong, N.5
Leach, S.D.6
Stoffers, D.A.7
-
29
-
-
79954563768
-
Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx
-
S. Dhawan, S. Georgia, S.I. Tschen, G. Fan, and A. Bhushan Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx Dev. Cell 20 2011 419 429
-
(2011)
Dev. Cell
, vol.20
, pp. 419-429
-
-
Dhawan, S.1
Georgia, S.2
Tschen, S.I.3
Fan, G.4
Bhushan, A.5
-
30
-
-
84864284886
-
Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells
-
D. Direnzo, D.A. Hess, B. Damsz, J.E. Hallett, B. Marshall, C. Goswami, Y. Liu, T. Deering, R.J. Macdonald, and S.F. Konieczny Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells Gastroenterology 143 2012 469 480
-
(2012)
Gastroenterology
, vol.143
, pp. 469-480
-
-
Direnzo, D.1
Hess, D.A.2
Damsz, B.3
Hallett, J.E.4
Marshall, B.5
Goswami, C.6
Liu, Y.7
Deering, T.8
Macdonald, R.J.9
Konieczny, S.F.10
-
32
-
-
84904258511
-
Aberrant innate immune activation following tissue injury impairs pancreatic regeneration
-
A.E. Folias, C. Penaranda, A.L. Su, J.A. Bluestone, and M. Hebrok Aberrant innate immune activation following tissue injury impairs pancreatic regeneration PLoS ONE 9 2014 e102125
-
(2014)
PLoS ONE
, vol.9
, pp. e102125
-
-
Folias, A.E.1
Penaranda, C.2
Su, A.L.3
Bluestone, J.A.4
Hebrok, M.5
-
33
-
-
38949149704
-
Pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
-
M. Gannon, E.T. Ables, L. Crawford, D. Lowe, M.F. Offield, M.A. Magnuson, and C.V. Wright pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis Dev. Biol. 314 2008 406 417
-
(2008)
Dev. Biol.
, vol.314
, pp. 406-417
-
-
Gannon, M.1
Ables, E.T.2
Crawford, L.3
Lowe, D.4
Offield, M.F.5
Magnuson, M.A.6
Wright, C.V.7
-
34
-
-
84893510559
-
Pdx1 maintains β cell identity and function by repressing an α cell program
-
T. Gao, B. McKenna, C. Li, M. Reichert, J. Nguyen, T. Singh, C. Yang, A. Pannikar, N. Doliba, and T. Zhang Pdx1 maintains β cell identity and function by repressing an α cell program Cell Metab. 19 2014 259 271
-
(2014)
Cell Metab.
, vol.19
, pp. 259-271
-
-
Gao, T.1
McKenna, B.2
Li, C.3
Reichert, M.4
Nguyen, J.5
Singh, T.6
Yang, C.7
Pannikar, A.8
Doliba, N.9
Zhang, T.10
-
35
-
-
82755182204
-
Historical origins of transdifferentiation and reprogramming
-
T. Graf Historical origins of transdifferentiation and reprogramming Cell Stem Cell 9 2011 504 516
-
(2011)
Cell Stem Cell
, vol.9
, pp. 504-516
-
-
Graf, T.1
-
36
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
G. Gu, J. Dubauskaite, and D.A. Melton Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors Development 129 2002 2447 2457
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
37
-
-
33847419143
-
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
-
C. Guerra, A.J. Schuhmacher, M. Cañamero, P.J. Grippo, L. Verdaguer, L. Pérez-Gallego, P. Dubus, E.P. Sandgren, and M. Barbacid Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice Cancer Cell 11 2007 291 302
-
(2007)
Cancer Cell
, vol.11
, pp. 291-302
-
-
Guerra, C.1
Schuhmacher, A.J.2
Cañamero, M.3
Grippo, P.J.4
Verdaguer, L.5
Pérez-Gallego, L.6
Dubus, P.7
Sandgren, E.P.8
Barbacid, M.9
-
38
-
-
84881218353
-
Inactivation of specific β cell transcription factors in type 2 diabetes
-
S. Guo, C. Dai, M. Guo, B. Taylor, J.S. Harmon, M. Sander, R.P. Robertson, A.C. Powers, and R. Stein Inactivation of specific β cell transcription factors in type 2 diabetes J. Clin. Invest. 123 2013 3305 3316
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3305-3316
-
-
Guo, S.1
Dai, C.2
Guo, M.3
Taylor, B.4
Harmon, J.S.5
Sander, M.6
Robertson, R.P.7
Powers, A.C.8
Stein, R.9
-
39
-
-
57749113202
-
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice
-
N. Habbe, G. Shi, R.A. Meguid, V. Fendrich, F. Esni, H. Chen, G. Feldmann, D.A. Stoffers, S.F. Konieczny, S.D. Leach, and A. Maitra Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice Proc. Natl. Acad. Sci. USA 105 2008 18913 18918
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18913-18918
-
-
Habbe, N.1
Shi, G.2
Meguid, R.A.3
Fendrich, V.4
Esni, F.5
Chen, H.6
Feldmann, G.7
Stoffers, D.A.8
Konieczny, S.F.9
Leach, S.D.10
Maitra, A.11
-
40
-
-
14244266611
-
Minireview: Transcriptional regulation in pancreatic development
-
J.F. Habener, D.M. Kemp, and M.K. Thomas Minireview: transcriptional regulation in pancreatic development Endocrinology 146 2005 1025 1034
-
(2005)
Endocrinology
, vol.146
, pp. 1025-1034
-
-
Habener, J.F.1
Kemp, D.M.2
Thomas, M.K.3
-
41
-
-
0032852505
-
In vivo prevention of hyperglycemia also prevents glucotoxic effects on PDX-1 and insulin gene expression
-
J.S. Harmon, C.E. Gleason, Y. Tanaka, E.A. Oseid, K.K. Hunter-Berger, and R.P. Robertson In vivo prevention of hyperglycemia also prevents glucotoxic effects on PDX-1 and insulin gene expression Diabetes 48 1999 1995 2000
-
(1999)
Diabetes
, vol.48
, pp. 1995-2000
-
-
Harmon, J.S.1
Gleason, C.E.2
Tanaka, Y.3
Oseid, E.A.4
Hunter-Berger, K.K.5
Robertson, R.P.6
-
42
-
-
84872248207
-
The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreas
-
A.W. Hart, S. Mella, J. Mendrychowski, V. van Heyningen, and D.A. Kleinjan The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreas PLoS ONE 8 2013 e54173
-
(2013)
PLoS ONE
, vol.8
, pp. e54173
-
-
Hart, A.W.1
Mella, S.2
Mendrychowski, J.3
Van Heyningen, V.4
Kleinjan, D.A.5
-
43
-
-
13444257370
-
Lack of TCF2/vHNF1 in mice leads to pancreas agenesis
-
C. Haumaitre, E. Barbacci, M. Jenny, M.O. Ott, G. Gradwohl, and S. Cereghini Lack of TCF2/vHNF1 in mice leads to pancreas agenesis Proc. Natl. Acad. Sci. USA 102 2005 1490 1495
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1490-1495
-
-
Haumaitre, C.1
Barbacci, E.2
Jenny, M.3
Ott, M.O.4
Gradwohl, G.5
Cereghini, S.6
-
44
-
-
53549088061
-
Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors
-
C. Haumaitre, O. Lenoir, and R. Scharfmann Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors Mol. Cell. Biol. 28 2008 6373 6383
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 6373-6383
-
-
Haumaitre, C.1
Lenoir, O.2
Scharfmann, R.3
-
45
-
-
79955430577
-
Suppression of Ptf1a activity induces acinar-to-endocrine conversion
-
D. Hesselson, R.M. Anderson, and D.Y. Stainier Suppression of Ptf1a activity induces acinar-to-endocrine conversion Curr. Biol. 21 2011 712 717
-
(2011)
Curr. Biol.
, vol.21
, pp. 712-717
-
-
Hesselson, D.1
Anderson, R.M.2
Stainier, D.Y.3
-
46
-
-
84860390430
-
LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function
-
S.R. Holmstrom, T. Deering, G.H. Swift, F.J. Poelwijk, D.J. Mangelsdorf, S.A. Kliewer, and R.J. MacDonald LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function Genes Dev. 25 2011 1674 1679
-
(2011)
Genes Dev.
, vol.25
, pp. 1674-1679
-
-
Holmstrom, S.R.1
Deering, T.2
Swift, G.H.3
Poelwijk, F.J.4
Mangelsdorf, D.J.5
Kliewer, S.A.6
Macdonald, R.J.7
-
47
-
-
66449090934
-
Reprogramming cell fates: Reconciling rarity with robustness
-
S. Huang Reprogramming cell fates: reconciling rarity with robustness BioEssays 31 2009 546 560
-
(2009)
BioEssays
, vol.31
, pp. 546-560
-
-
Huang, S.1
-
48
-
-
20444482821
-
Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: Application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes
-
T. Iype, J. Francis, J.C. Garmey, J.C. Schisler, R. Nesher, G.C. Weir, T.C. Becker, C.B. Newgard, S.C. Griffen, and R.G. Mirmira Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes J. Biol. Chem. 280 2005 16798 16807
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16798-16807
-
-
Iype, T.1
Francis, J.2
Garmey, J.C.3
Schisler, J.C.4
Nesher, R.5
Weir, G.C.6
Becker, T.C.7
Newgard, C.B.8
Griffen, S.C.9
Mirmira, R.G.10
-
49
-
-
0038360823
-
The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade
-
P. Jacquemin, F.P. Lemaigre, and G.G. Rousseau The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade Dev. Biol. 258 2003 105 116
-
(2003)
Dev. Biol.
, vol.258
, pp. 105-116
-
-
Jacquemin, P.1
Lemaigre, F.P.2
Rousseau, G.G.3
-
50
-
-
15744400264
-
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration
-
J.N. Jensen, E. Cameron, M.V. Garay, T.W. Starkey, R. Gianani, and J. Jensen Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration Gastroenterology 128 2005 728 741
-
(2005)
Gastroenterology
, vol.128
, pp. 728-741
-
-
Jensen, J.N.1
Cameron, E.2
Garay, M.V.3
Starkey, T.W.4
Gianani, R.5
Jensen, J.6
-
51
-
-
0033553462
-
Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes
-
J.C. Jonas, A. Sharma, W. Hasenkamp, H. Ilkova, G. Patanè, R. Laybutt, S. Bonner-Weir, and G.C. Weir Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes J. Biol. Chem. 274 1999 14112 14121
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14112-14121
-
-
Jonas, J.C.1
Sharma, A.2
Hasenkamp, W.3
Ilkova, H.4
Patanè, G.5
Laybutt, R.6
Bonner-Weir, S.7
Weir, G.C.8
-
52
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
J. Jonsson, L. Carlsson, T. Edlund, and H. Edlund Insulin-promoter-factor 1 is required for pancreas development in mice Nature 371 1994 606 609
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
53
-
-
78951478823
-
Dedifferentiation, transdifferentiation and reprogramming: Three routes to regeneration
-
C. Jopling, S. Boue, and J.C. Izpisua Belmonte Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration Nat. Rev. Mol. Cell Biol. 12 2011 79 89
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 79-89
-
-
Jopling, C.1
Boue, S.2
Izpisua Belmonte, J.C.3
-
54
-
-
0036796941
-
Ductal and acinar differentiation in pancreatic endocrine tumors
-
T. Kamisawa, Y. Tu, N. Egawa, J. Ishiwata, K. Tsuruta, A. Okamoto, Y. Hayashi, M. Koike, and T. Yamaguchi Ductal and acinar differentiation in pancreatic endocrine tumors Dig. Dis. Sci. 47 2002 2254 2261
-
(2002)
Dig. Dis. Sci.
, vol.47
, pp. 2254-2261
-
-
Kamisawa, T.1
Tu, Y.2
Egawa, N.3
Ishiwata, J.4
Tsuruta, K.5
Okamoto, A.6
Hayashi, Y.7
Koike, M.8
Yamaguchi, T.9
-
55
-
-
84901835072
-
Could microRNAs contribute to the maintenance of β cell identity?
-
H. Kaspi, R. Pasvolsky, and E. Hornstein Could microRNAs contribute to the maintenance of β cell identity? Trends Endocrinol. Metab. 25 2014 285 292
-
(2014)
Trends Endocrinol. Metab.
, vol.25
, pp. 285-292
-
-
Kaspi, H.1
Pasvolsky, R.2
Hornstein, E.3
-
56
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
-
Y. Kawaguchi, B. Cooper, M. Gannon, M. Ray, R.J. MacDonald, and C.V. Wright The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors Nat. Genet. 32 2002 128 134
-
(2002)
Nat. Genet.
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
Macdonald, R.J.5
Wright, C.V.6
-
57
-
-
80054799278
-
Classification and pathology of gastroenteropancreatic neuroendocrine neoplasms
-
G. Klöppel Classification and pathology of gastroenteropancreatic neuroendocrine neoplasms Endocr. Relat. Cancer 18 1 2011 S1 S16
-
(2011)
Endocr. Relat. Cancer
, vol.18
, Issue.1
, pp. S1-S16
-
-
Klöppel, G.1
-
58
-
-
78751515624
-
Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas
-
D. Kopinke, M. Brailsford, J.E. Shea, R. Leavitt, C.L. Scaife, and L.C. Murtaugh Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas Development 138 2011 431 441
-
(2011)
Development
, vol.138
, pp. 431-441
-
-
Kopinke, D.1
Brailsford, M.2
Shea, J.E.3
Leavitt, R.4
Scaife, C.L.5
Murtaugh, L.C.6
-
59
-
-
84855460172
-
Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas
-
D. Kopinke, M. Brailsford, F.C. Pan, M.A. Magnuson, C.V. Wright, and L.C. Murtaugh Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas Dev. Biol. 362 2012 57 64
-
(2012)
Dev. Biol.
, vol.362
, pp. 57-64
-
-
Kopinke, D.1
Brailsford, M.2
Pan, F.C.3
Magnuson, M.A.4
Wright, C.V.5
Murtaugh, L.C.6
-
60
-
-
79951539242
-
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
-
J.L. Kopp, C.L. Dubois, A.E. Schaffer, E. Hao, H.P. Shih, P.A. Seymour, J. Ma, and M. Sander Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas Development 138 2011 653 665
-
(2011)
Development
, vol.138
, pp. 653-665
-
-
Kopp, J.L.1
Dubois, C.L.2
Schaffer, A.E.3
Hao, E.4
Shih, H.P.5
Seymour, P.A.6
Ma, J.7
Sander, M.8
-
61
-
-
84870803922
-
Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma
-
J.L. Kopp, G. von Figura, E. Mayes, F.F. Liu, C.L. Dubois, J.P. Morris 4th, F.C. Pan, H. Akiyama, C.V. Wright, and K. Jensen Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma Cancer Cell 22 2012 737 750
-
(2012)
Cancer Cell
, vol.22
, pp. 737-750
-
-
Kopp, J.L.1
Von Figura, G.2
Mayes, E.3
Liu, F.F.4
Dubois, C.L.5
Morris, J.P.6
Pan, F.C.7
Akiyama, H.8
Wright, C.V.9
Jensen, K.10
-
62
-
-
80052177191
-
Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage
-
S. Kordowich, P. Collombat, A. Mansouri, and P. Serup Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage BMC Dev. Biol. 11 2011 52
-
(2011)
BMC Dev. Biol.
, vol.11
, pp. 52
-
-
Kordowich, S.1
Collombat, P.2
Mansouri, A.3
Serup, P.4
-
63
-
-
84859463823
-
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells
-
S. Kubicek, J.C. Gilbert, D. Fomina-Yadlin, A.D. Gitlin, Y. Yuan, F.F. Wagner, E.B. Holson, T. Luo, T.A. Lewis, and B. Taylor Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells Proc. Natl. Acad. Sci. USA 109 2012 5364 5369
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 5364-5369
-
-
Kubicek, S.1
Gilbert, J.C.2
Fomina-Yadlin, D.3
Gitlin, A.D.4
Yuan, Y.5
Wagner, F.F.6
Holson, E.B.7
Luo, T.8
Lewis, T.A.9
Taylor, B.10
-
64
-
-
80054743186
-
Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice
-
L. Landsman, A. Parent, and M. Hebrok Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice Proc. Natl. Acad. Sci. USA 108 2011 17010 17015
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 17010-17015
-
-
Landsman, L.1
Parent, A.2
Hebrok, M.3
-
65
-
-
80755168896
-
Specific control of pancreatic endocrine β- And δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9
-
O. Lenoir, K. Flosseau, F.X. Ma, B. Blondeau, A. Mai, R. Bassel-Duby, P. Ravassard, E.N. Olson, C. Haumaitre, and R. Scharfmann Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9 Diabetes 60 2011 2861 2871
-
(2011)
Diabetes
, vol.60
, pp. 2861-2871
-
-
Lenoir, O.1
Flosseau, K.2
Ma, F.X.3
Blondeau, B.4
Mai, A.5
Bassel-Duby, R.6
Ravassard, P.7
Olson, E.N.8
Haumaitre, C.9
Scharfmann, R.10
-
66
-
-
84899800252
-
In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes
-
W. Li, M. Nakanishi, A. Zumsteg, M. Shear, C. Wright, D.A. Melton, and Q. Zhou In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes eLife 3 2014 e01846
-
(2014)
ELife
, vol.3
, pp. e01846
-
-
Li, W.1
Nakanishi, M.2
Zumsteg, A.3
Shear, M.4
Wright, C.5
Melton, D.A.6
Zhou, Q.7
-
67
-
-
2942616871
-
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas
-
J.W. Lin, A.V. Biankin, M.E. Horb, B. Ghosh, N.B. Prasad, N.S. Yee, M.A. Pack, and S.D. Leach Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas Dev. Biol. 270 2004 474 486
-
(2004)
Dev. Biol.
, vol.270
, pp. 474-486
-
-
Lin, J.W.1
Biankin, A.V.2
Horb, M.E.3
Ghosh, B.4
Prasad, N.B.5
Yee, N.S.6
Pack, M.A.7
Leach, S.D.8
-
68
-
-
77951840060
-
Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development
-
J. Lu, P.L. Herrera, C. Carreira, R. Bonnavion, C. Seigne, A. Calender, P. Bertolino, and C.X. Zhang Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development Gastroenterology 138 2010 1954 1965
-
(2010)
Gastroenterology
, vol.138
, pp. 1954-1965
-
-
Lu, J.1
Herrera, P.L.2
Carreira, C.3
Bonnavion, R.4
Seigne, C.5
Calender, A.6
Bertolino, P.7
Zhang, C.X.8
-
69
-
-
36248978699
-
MicroRNA expression is required for pancreatic islet cell genesis in the mouse
-
F.C. Lynn, P. Skewes-Cox, Y. Kosaka, M.T. McManus, B.D. Harfe, and M.S. German MicroRNA expression is required for pancreatic islet cell genesis in the mouse Diabetes 56 2007 2938 2945
-
(2007)
Diabetes
, vol.56
, pp. 2938-2945
-
-
Lynn, F.C.1
Skewes-Cox, P.2
Kosaka, Y.3
McManus, M.T.4
Harfe, B.D.5
German, M.S.6
-
70
-
-
84861221146
-
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration
-
I. Manfroid, A. Ghaye, F. Naye, N. Detry, S. Palm, L. Pan, T.P. Ma, W. Huang, M. Rovira, and J.A. Martial Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration Dev. Biol. 366 2012 268 278
-
(2012)
Dev. Biol.
, vol.366
, pp. 268-278
-
-
Manfroid, I.1
Ghaye, A.2
Naye, F.3
Detry, N.4
Palm, S.5
Pan, L.6
Ma, T.P.7
Huang, W.8
Rovira, M.9
Martial, J.A.10
-
71
-
-
84903141772
-
Development and regeneration in the endocrine pancreas
-
A. Mansouri Development and regeneration in the endocrine pancreas ISRN Endocrinol. 2012 2012 640956
-
(2012)
ISRN Endocrinol.
, vol.2012
, pp. 640956
-
-
Mansouri, A.1
-
72
-
-
80053580232
-
Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression
-
T.L. Mastracci, C.L. Wilcox, L. Arnes, C. Panea, J.A. Golden, C.L. May, and L. Sussel Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression Dev. Biol. 359 2011 1 11
-
(2011)
Dev. Biol.
, vol.359
, pp. 1-11
-
-
Mastracci, T.L.1
Wilcox, C.L.2
Arnes, L.3
Panea, C.4
Golden, J.A.5
May, C.L.6
Sussel, L.7
-
74
-
-
10744223624
-
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
-
Y. Miyamoto, A. Maitra, B. Ghosh, U. Zechner, P. Argani, C.A. Iacobuzio-Donahue, V. Sriuranpong, T. Iso, I.M. Meszoely, and M.S. Wolfe Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis Cancer Cell 3 2003 565 576
-
(2003)
Cancer Cell
, vol.3
, pp. 565-576
-
-
Miyamoto, Y.1
Maitra, A.2
Ghosh, B.3
Zechner, U.4
Argani, P.5
Iacobuzio-Donahue, C.A.6
Sriuranpong, V.7
Iso, T.8
Meszoely, I.M.9
Wolfe, M.S.10
-
75
-
-
76649105065
-
Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
-
J.P. Morris 4th, D.A. Cano, S. Sekine, S.C. Wang, and M. Hebrok Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice J. Clin. Invest. 120 2010 508 520
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 508-520
-
-
Morris, J.P.1
Cano, D.A.2
Sekine, S.3
Wang, S.C.4
Hebrok, M.5
-
76
-
-
77957150824
-
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
-
J.P. Morris 4th, S.C. Wang, and M. Hebrok KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma Nat. Rev. Cancer 10 2010 683 695
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 683-695
-
-
Morris, J.P.1
Wang, S.C.2
Hebrok, M.3
-
77
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
M.F. Offield, T.L. Jetton, P.A. Labosky, M. Ray, R.W. Stein, M.A. Magnuson, B.L. Hogan, and C.V. Wright PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum Development 122 1996 983 995
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
Ray, M.4
Stein, R.W.5
Magnuson, M.A.6
Hogan, B.L.7
Wright, C.V.8
-
78
-
-
84873111871
-
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration
-
F.C. Pan, E.D. Bankaitis, D. Boyer, X. Xu, M. Van de Casteele, M.A. Magnuson, H. Heimberg, and C.V. Wright Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration Development 140 2013 751 764
-
(2013)
Development
, vol.140
, pp. 751-764
-
-
Pan, F.C.1
Bankaitis, E.D.2
Boyer, D.3
Xu, X.4
Van De Casteele, M.5
Magnuson, M.A.6
Heimberg, H.7
Wright, C.V.8
-
79
-
-
80455173402
-
Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming
-
J.B. Papizan, R.A. Singer, S.I. Tschen, S. Dhawan, J.M. Friel, S.B. Hipkens, M.A. Magnuson, A. Bhushan, and L. Sussel Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming Genes Dev. 25 2011 2291 2305
-
(2011)
Genes Dev.
, vol.25
, pp. 2291-2305
-
-
Papizan, J.B.1
Singer, R.A.2
Tschen, S.I.3
Dhawan, S.4
Friel, J.M.5
Hipkens, S.B.6
Magnuson, M.A.7
Bhushan, A.8
Sussel, L.9
-
80
-
-
32044438892
-
The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse
-
C.E. Pierreux, A.V. Poll, C.R. Kemp, F. Clotman, M.A. Maestro, S. Cordi, J. Ferrer, L. Leyns, G.G. Rousseau, and F.P. Lemaigre The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse Gastroenterology 130 2006 532 541
-
(2006)
Gastroenterology
, vol.130
, pp. 532-541
-
-
Pierreux, C.E.1
Poll, A.V.2
Kemp, C.R.3
Clotman, F.4
Maestro, M.A.5
Cordi, S.6
Ferrer, J.7
Leyns, L.8
Rousseau, G.G.9
Lemaigre, F.P.10
-
81
-
-
84924133024
-
The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity
-
C.L. Pin, J.M. Rukstalis, C. Johnson, and S.F. Konieczny The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity J. Cell Biol. 155 2001 519 530
-
(2001)
J. Cell Biol.
, vol.155
, pp. 519-530
-
-
Pin, C.L.1
Rukstalis, J.M.2
Johnson, C.3
Konieczny, S.F.4
-
82
-
-
43549108142
-
Glucolipotoxicity: Fuel excess and beta-cell dysfunction
-
V. Poitout, and R.P. Robertson Glucolipotoxicity: fuel excess and beta-cell dysfunction Endocr. Rev. 29 2008 351 366
-
(2008)
Endocr. Rev.
, vol.29
, pp. 351-366
-
-
Poitout, V.1
Robertson, R.P.2
-
83
-
-
9144270691
-
A pancreatic islet-specific microRNA regulates insulin secretion
-
M.N. Poy, L. Eliasson, J. Krutzfeldt, S. Kuwajima, X. Ma, P.E. Macdonald, S. Pfeffer, T. Tuschl, N. Rajewsky, P. Rorsman, and M. Stoffel A pancreatic islet-specific microRNA regulates insulin secretion Nature 432 2004 226 230
-
(2004)
Nature
, vol.432
, pp. 226-230
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
Kuwajima, S.4
Ma, X.5
Macdonald, P.E.6
Pfeffer, S.7
Tuschl, T.8
Rajewsky, N.9
Rorsman, P.10
Stoffel, M.11
-
84
-
-
65249093130
-
MiR-375 maintains normal pancreatic alpha- and beta-cell mass
-
M.N. Poy, J. Hausser, M. Trajkovski, M. Braun, S. Collins, P. Rorsman, M. Zavolan, and M. Stoffel miR-375 maintains normal pancreatic alpha- and beta-cell mass Proc. Natl. Acad. Sci. USA 106 2009 5813 5818
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 5813-5818
-
-
Poy, M.N.1
Hausser, J.2
Trajkovski, M.3
Braun, M.4
Collins, S.5
Rorsman, P.6
Zavolan, M.7
Stoffel, M.8
-
85
-
-
84868698484
-
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia
-
P.P. Prévot, A. Simion, A. Grimont, M. Colletti, A. Khalaileh, G. Van den Steen, C. Sempoux, X. Xu, V. Roelants, and J. Hald Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia Gut 61 2012 1723 1732
-
(2012)
Gut
, vol.61
, pp. 1723-1732
-
-
Prévot, P.P.1
Simion, A.2
Grimont, A.3
Colletti, M.4
Khalaileh, A.5
Van Den Steen, G.6
Sempoux, C.7
Xu, X.8
Roelants, V.9
Hald, J.10
-
86
-
-
84883184456
-
Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6
-
e663
-
P.P. Prevot, C. Augereau, A. Simion, G. Van den Steen, N. Dauguet, F.P. Lemaigre, and P. Jacquemin Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6 Gastroenterology 145 2013 668 678 e663
-
(2013)
Gastroenterology
, vol.145
, pp. 668-678
-
-
Prevot, P.P.1
Augereau, C.2
Simion, A.3
Van Den Steen, G.4
Dauguet, N.5
Lemaigre, F.P.6
Jacquemin, P.7
-
87
-
-
79960322580
-
MiR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1)
-
T.J. Pullen, G. da Silva Xavier, G. Kelsey, and G.A. Rutter miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1) Mol. Cell. Biol. 31 2011 3182 3194
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 3182-3194
-
-
Pullen, T.J.1
Da Silva Xavier, G.2
Kelsey, G.3
Rutter, G.A.4
-
88
-
-
84888798787
-
VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus
-
S. Puri, H. Akiyama, and M. Hebrok VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus Genes Dev. 27 2013 2563 2575
-
(2013)
Genes Dev.
, vol.27
, pp. 2563-2575
-
-
Puri, S.1
Akiyama, H.2
Hebrok, M.3
-
89
-
-
84862147254
-
Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia
-
Y. Pylayeva-Gupta, K.E. Lee, C.H. Hajdu, G. Miller, and D. Bar-Sagi Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia Cancer Cell 21 2012 836 847
-
(2012)
Cancer Cell
, vol.21
, pp. 836-847
-
-
Pylayeva-Gupta, Y.1
Lee, K.E.2
Hajdu, C.H.3
Miller, G.4
Bar-Sagi, D.5
-
90
-
-
78751502673
-
Production of functional glucagon-secreting α-cells from human embryonic stem cells
-
A. Rezania, M.J. Riedel, R.D. Wideman, F. Karanu, Z. Ao, G.L. Warnock, and T.J. Kieffer Production of functional glucagon-secreting α-cells from human embryonic stem cells Diabetes 60 2011 239 247
-
(2011)
Diabetes
, vol.60
, pp. 239-247
-
-
Rezania, A.1
Riedel, M.J.2
Wideman, R.D.3
Karanu, F.4
Ao, Z.5
Warnock, G.L.6
Kieffer, T.J.7
-
91
-
-
76249094159
-
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
-
M. Rovira, S.G. Scott, A.S. Liss, J. Jensen, S.P. Thayer, and S.D. Leach Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas Proc. Natl. Acad. Sci. USA 107 2010 75 80
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 75-80
-
-
Rovira, M.1
Scott, S.G.2
Liss, A.S.3
Jensen, J.4
Thayer, S.P.5
Leach, S.D.6
-
92
-
-
84905815332
-
Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells
-
R. Sancho, R. Gruber, G. Gu, and A. Behrens Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells Cell Stem Cell 15 2014 139 153
-
(2014)
Cell Stem Cell
, vol.15
, pp. 139-153
-
-
Sancho, R.1
Gruber, R.2
Gu, G.3
Behrens, A.4
-
93
-
-
77955978501
-
Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors
-
A.E. Schaffer, K.K. Freude, S.B. Nelson, and M. Sander Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors Dev. Cell 18 2010 1022 1029
-
(2010)
Dev. Cell
, vol.18
, pp. 1022-1029
-
-
Schaffer, A.E.1
Freude, K.K.2
Nelson, S.B.3
Sander, M.4
-
94
-
-
84873514082
-
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity
-
A.E. Schaffer, B.L. Taylor, J.R. Benthuysen, J. Liu, F. Thorel, W. Yuan, Y. Jiao, K.H. Kaestner, P.L. Herrera, and M.A. Magnuson Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity PLoS Genet. 9 2013 e1003274
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003274
-
-
Schaffer, A.E.1
Taylor, B.L.2
Benthuysen, J.R.3
Liu, J.4
Thorel, F.5
Yuan, W.6
Jiao, Y.7
Kaestner, K.H.8
Herrera, P.L.9
Magnuson, M.A.10
-
95
-
-
33846910410
-
SOX9 is required for maintenance of the pancreatic progenitor cell pool
-
P.A. Seymour, K.K. Freude, M.N. Tran, E.E. Mayes, J. Jensen, R. Kist, G. Scherer, and M. Sander SOX9 is required for maintenance of the pancreatic progenitor cell pool Proc. Natl. Acad. Sci. USA 104 2007 1865 1870
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1865-1870
-
-
Seymour, P.A.1
Freude, K.K.2
Tran, M.N.3
Mayes, E.E.4
Jensen, J.5
Kist, R.6
Scherer, G.7
Sander, M.8
-
96
-
-
53649102798
-
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
-
P.A. Seymour, K.K. Freude, C.L. Dubois, H.P. Shih, N.A. Patel, and M. Sander A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation Dev. Biol. 323 2008 19 30
-
(2008)
Dev. Biol.
, vol.323
, pp. 19-30
-
-
Seymour, P.A.1
Freude, K.K.2
Dubois, C.L.3
Shih, H.P.4
Patel, N.A.5
Sander, M.6
-
97
-
-
84894442406
-
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome
-
L. Shang, H. Hua, K. Foo, H. Martinez, K. Watanabe, M. Zimmer, D.J. Kahler, M. Freeby, W. Chung, and C. LeDuc β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome Diabetes 63 2014 923 933
-
(2014)
Diabetes
, vol.63
, pp. 923-933
-
-
Shang, L.1
Hua, H.2
Foo, K.3
Martinez, H.4
Watanabe, K.5
Zimmer, M.6
Kahler, D.J.7
Freeby, M.8
Chung, W.9
Leduc, C.10
-
98
-
-
83155172444
-
Intraductal papillary mucinous neoplasm
-
C. Shi, and R.H. Hruban Intraductal papillary mucinous neoplasm Hum. Pathol. 43 2012 1 16
-
(2012)
Hum. Pathol.
, vol.43
, pp. 1-16
-
-
Shi, C.1
Hruban, R.H.2
-
99
-
-
84876125422
-
Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia
-
G. Shi, D. DiRenzo, C. Qu, D. Barney, D. Miley, and S.F. Konieczny Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia Oncogene 32 2013 1950 1958
-
(2013)
Oncogene
, vol.32
, pp. 1950-1958
-
-
Shi, G.1
Direnzo, D.2
Qu, C.3
Barney, D.4
Miley, D.5
Konieczny, S.F.6
-
100
-
-
38649140167
-
Notch signaling is required for exocrine regeneration after acute pancreatitis
-
J.T. Siveke, C. Lubeseder-Martellato, M. Lee, P.K. Mazur, H. Nakhai, F. Radtke, and R.M. Schmid Notch signaling is required for exocrine regeneration after acute pancreatitis Gastroenterology 134 2008 544 555
-
(2008)
Gastroenterology
, vol.134
, pp. 544-555
-
-
Siveke, J.T.1
Lubeseder-Martellato, C.2
Lee, M.3
Mazur, P.K.4
Nakhai, H.5
Radtke, F.6
Schmid, R.M.7
-
101
-
-
71649092364
-
Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth
-
M. Solar, C. Cardalda, I. Houbracken, M. Martín, M.A. Maestro, N. De Medts, X. Xu, V. Grau, H. Heimberg, L. Bouwens, and J. Ferrer Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth Dev. Cell 17 2009 849 860
-
(2009)
Dev. Cell
, vol.17
, pp. 849-860
-
-
Solar, M.1
Cardalda, C.2
Houbracken, I.3
Martín, M.4
Maestro, M.A.5
De Medts, N.6
Xu, X.7
Grau, V.8
Heimberg, H.9
Bouwens, L.10
Ferrer, J.11
-
102
-
-
0032734761
-
Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha
-
S.Y. Song, M. Gannon, M.K. Washington, C.R. Scoggins, I.M. Meszoely, J.R. Goldenring, C.R. Marino, E.P. Sandgren, R.J. Coffey Jr., C.V. Wright, and S.D. Leach Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha Gastroenterology 117 1999 1416 1426
-
(1999)
Gastroenterology
, vol.117
, pp. 1416-1426
-
-
Song, S.Y.1
Gannon, M.2
Washington, M.K.3
Scoggins, C.R.4
Meszoely, I.M.5
Goldenring, J.R.6
Marino, C.R.7
Sandgren, E.P.8
Coffey, Jr.R.J.9
Wright, C.V.10
Leach, S.D.11
-
103
-
-
84883722508
-
Conversion of mature human β-cells into glucagon-producing α-cells
-
H.S. Spijker, R.B. Ravelli, A.M. Mommaas-Kienhuis, A.A. van Apeldoorn, M.A. Engelse, A. Zaldumbide, S. Bonner-Weir, T.J. Rabelink, R.C. Hoeben, and H. Clevers Conversion of mature human β-cells into glucagon-producing α-cells Diabetes 62 2013 2471 2480
-
(2013)
Diabetes
, vol.62
, pp. 2471-2480
-
-
Spijker, H.S.1
Ravelli, R.B.2
Mommaas-Kienhuis, A.M.3
Van Apeldoorn, A.A.4
Engelse, M.A.5
Zaldumbide, A.6
Bonner-Weir, S.7
Rabelink, T.J.8
Hoeben, R.C.9
Clevers, H.10
-
105
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
-
D.A. Stoffers, N.T. Zinkin, V. Stanojevic, W.L. Clarke, and J.F. Habener Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence Nat. Genet. 15 1997 106 110
-
(1997)
Nat. Genet.
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
Clarke, W.L.4
Habener, J.F.5
-
106
-
-
84860994977
-
Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming
-
N. Swales, G.A. Martens, S. Bonné, Y. Heremans, R. Borup, M. Van de Casteele, Z. Ling, D. Pipeleers, P. Ravassard, and F. Nielsen Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming PLoS ONE 7 2012 e37055
-
(2012)
PLoS ONE
, vol.7
, pp. e37055
-
-
Swales, N.1
Martens, G.A.2
Bonné, S.3
Heremans, Y.4
Borup, R.5
Van De Casteele, M.6
Ling, Z.7
Pipeleers, D.8
Ravassard, P.9
Nielsen, F.10
-
107
-
-
84866389264
-
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
-
C. Talchai, S. Xuan, H.V. Lin, L. Sussel, and D. Accili Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure Cell 150 2012 1223 1234
-
(2012)
Cell
, vol.150
, pp. 1223-1234
-
-
Talchai, C.1
Xuan, S.2
Lin, H.V.3
Sussel, L.4
Accili, D.5
-
108
-
-
77951611220
-
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
-
F. Thorel, V. Népote, I. Avril, K. Kohno, R. Desgraz, S. Chera, and P.L. Herrera Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss Nature 464 2010 1149 1154
-
(2010)
Nature
, vol.464
, pp. 1149-1154
-
-
Thorel, F.1
Népote, V.2
Avril, I.3
Kohno, K.4
Desgraz, R.5
Chera, S.6
Herrera, P.L.7
-
109
-
-
84895432066
-
The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma
-
G. von Figura, A. Fukuda, N. Roy, M.E. Liku, J.P. Morris Iv, G.E. Kim, H.A. Russ, M.A. Firpo, S.J. Mulvihill, and D.W. Dawson The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma Nat. Cell Biol. 16 2014 255 267
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 255-267
-
-
Von Figura, G.1
Fukuda, A.2
Roy, N.3
Liku, M.E.4
Morris Iv, J.P.5
Kim, G.E.6
Russ, H.A.7
Firpo, M.A.8
Mulvihill, S.J.9
Dawson, D.W.10
-
110
-
-
84895442729
-
Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation
-
G. von Figura, J.P. Morris 4th, C.V. Wright, and M. Hebrok Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation Gut 63 2014 656 664
-
(2014)
Gut
, vol.63
, pp. 656-664
-
-
Von Figura, G.1
Morris, J.P.2
Wright, C.V.3
Hebrok, M.4
-
112
-
-
84900330718
-
Pancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy
-
Z. Wang, N.W. York, C.G. Nichols, and M.S. Remedi Pancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy Cell Metab. 19 2014 872 882
-
(2014)
Cell Metab.
, vol.19
, pp. 872-882
-
-
Wang, Z.1
York, N.W.2
Nichols, C.G.3
Remedi, M.S.4
-
113
-
-
84878983251
-
Pancreatic α-cell specific deletion of mouse Arx leads to α-cell identity loss
-
C.L. Wilcox, N.A. Terry, E.R. Walp, R.A. Lee, and C.L. May Pancreatic α-cell specific deletion of mouse Arx leads to α-cell identity loss PLoS ONE 8 2013 e66214
-
(2013)
PLoS ONE
, vol.8
, pp. e66214
-
-
Wilcox, C.L.1
Terry, N.A.2
Walp, E.R.3
Lee, R.A.4
May, C.L.5
-
114
-
-
0037213587
-
Gene expression cascades in pancreatic development
-
M.E. Wilson, D. Scheel, and M.S. German Gene expression cascades in pancreatic development Mech. Dev. 120 2003 65 80
-
(2003)
Mech. Dev.
, vol.120
, pp. 65-80
-
-
Wilson, M.E.1
Scheel, D.2
German, M.S.3
-
115
-
-
38749108893
-
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas
-
X. Xu, J. D'Hoker, G. Stangé, S. Bonné, N. De Leu, X. Xiao, M. Van de Casteele, G. Mellitzer, Z. Ling, and D. Pipeleers Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas Cell 132 2008 197 207
-
(2008)
Cell
, vol.132
, pp. 197-207
-
-
Xu, X.1
D'Hoker, J.2
Stangé, G.3
Bonné, S.4
De Leu, N.5
Xiao, X.6
Van De Casteele, M.7
Mellitzer, G.8
Ling, Z.9
Pipeleers, D.10
-
116
-
-
79956326274
-
Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas
-
C.R. Xu, P.A. Cole, D.J. Meyers, J. Kormish, S. Dent, and K.S. Zaret Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas Science 332 2011 963 966
-
(2011)
Science
, vol.332
, pp. 963-966
-
-
Xu, C.R.1
Cole, P.A.2
Meyers, D.J.3
Kormish, J.4
Dent, S.5
Zaret, K.S.6
-
117
-
-
84860410786
-
Context-specific α- To-β-cell reprogramming by forced Pdx1 expression
-
Y.P. Yang, F. Thorel, D.F. Boyer, P.L. Herrera, and C.V. Wright Context-specific α- to-β-cell reprogramming by forced Pdx1 expression Genes Dev. 25 2011 1680 1685
-
(2011)
Genes Dev.
, vol.25
, pp. 1680-1685
-
-
Yang, Y.P.1
Thorel, F.2
Boyer, D.F.3
Herrera, P.L.4
Wright, C.V.5
-
118
-
-
84860321700
-
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
-
H. Ying, A.C. Kimmelman, C.A. Lyssiotis, S. Hua, G.C. Chu, E. Fletcher-Sananikone, J.W. Locasale, J. Son, H. Zhang, and J.L. Coloff Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism Cell 149 2012 656 670
-
(2012)
Cell
, vol.149
, pp. 656-670
-
-
Ying, H.1
Kimmelman, A.C.2
Lyssiotis, C.A.3
Hua, S.4
Chu, G.C.5
Fletcher-Sananikone, E.6
Locasale, J.W.7
Son, J.8
Zhang, H.9
Coloff, J.L.10
-
119
-
-
70350608140
-
Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation
-
H. Zhang, E.T. Ables, C.F. Pope, M.K. Washington, S. Hipkens, A.L. Means, G. Path, J. Seufert, R.H. Costa, and A.B. Leiter Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation Mech. Dev. 126 2009 958 973
-
(2009)
Mech. Dev.
, vol.126
, pp. 958-973
-
-
Zhang, H.1
Ables, E.T.2
Pope, C.F.3
Washington, M.K.4
Hipkens, S.5
Means, A.L.6
Path, G.7
Seufert, J.8
Costa, R.H.9
Leiter, A.B.10
-
120
-
-
34250893048
-
A multipotent progenitor domain guides pancreatic organogenesis
-
Q. Zhou, A.C. Law, J. Rajagopal, W.J. Anderson, P.A. Gray, and D.A. Melton A multipotent progenitor domain guides pancreatic organogenesis Dev. Cell 13 2007 103 114
-
(2007)
Dev. Cell
, vol.13
, pp. 103-114
-
-
Zhou, Q.1
Law, A.C.2
Rajagopal, J.3
Anderson, W.J.4
Gray, P.A.5
Melton, D.A.6
-
121
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Q. Zhou, J. Brown, A. Kanarek, J. Rajagopal, and D.A. Melton In vivo reprogramming of adult pancreatic exocrine cells to beta-cells Nature 455 2008 627 632
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
|