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Volumn 18, Issue 6, 2010, Pages 1022-1029

Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; NKX6 1 PROTEIN, MOUSE; NKX6-1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PTF1;

EID: 77955978501     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2010.05.015     Document Type: Article
Times cited : (219)

References (32)
  • 2
    • 0034640087 scopus 로고    scopus 로고
    • A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
    • Briscoe, J., Pierani, A., Jessell, T.M., and Ericson, J. (2000). A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 101, 435-445.
    • (2000) Cell , vol.101 , pp. 435-445
    • Briscoe, J.1    Pierani, A.2    Jessell, T.M.3    Ericson, J.4
  • 3
    • 40949099880 scopus 로고    scopus 로고
    • Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells
    • Burlison, J.S., Long, Q., Fujitani, Y., Wright, C.V., and Magnuson, M.A. (2008). Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells. Dev. Biol. 316, 74-86.
    • (2008) Dev. Biol. , vol.316 , pp. 74-86
    • Burlison, J.S.1    Long, Q.2    Fujitani, Y.3    Wright, C.V.4    Magnuson, M.A.5
  • 4
    • 69749084211 scopus 로고    scopus 로고
    • Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window
    • Cras-Meneur, C., Li, L., Kopan, R., and Permutt, M.A. (2009). Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window. Genes Dev. 23, 2088-2101.
    • (2009) Genes Dev. , vol.23 , pp. 2088-2101
    • Cras-Meneur, C.1    Li, L.2    Kopan, R.3    Permutt, M.A.4
  • 5
    • 44849142042 scopus 로고    scopus 로고
    • Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas
    • Dong, P.D., Provost, E., Leach, S.D., and Stainier, D.Y. (2008). Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas. Genes Dev. 22, 1445-1450.
    • (2008) Genes Dev. , vol.22 , pp. 1445-1450
    • Dong, P.D.1    Provost, E.2    Leach, S.D.3    Stainier, D.Y.4
  • 8
    • 0036340074 scopus 로고    scopus 로고
    • Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
    • Gu, G., Dubauskaite, J., and Melton, D.A. (2002). Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 129, 2447-2457.
    • (2002) Development , vol.129 , pp. 2447-2457
    • Gu, G.1    Dubauskaite, J.2    Melton, D.A.3
  • 9
    • 43949111010 scopus 로고    scopus 로고
    • Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development
    • Hald, J., Sprinkel, A.E., Ray, M., Serup, P., Wright, C., and Madsen, O.D. (2008). Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development. J. Histochem. Cytochem. 56, 587-595.
    • (2008) J. Histochem. Cytochem. , vol.56 , pp. 587-595
    • Hald, J.1    Sprinkel, A.E.2    Ray, M.3    Serup, P.4    Wright, C.5    Madsen, O.D.6
  • 10
    • 23144437373 scopus 로고    scopus 로고
    • NKX6 transcription factor activity is required for a- and b-cell development in the pancreas
    • Henseleit, K.D., Nelson, S.B., Kuhlbrodt, K., Hennings, J.C., Ericson, J., and Sander, M. (2005). NKX6 transcription factor activity is required for a- and b-cell development in the pancreas. Development 132, 3139-3149.
    • (2005) Development , vol.132 , pp. 3139-3149
    • Henseleit, K.D.1    Nelson, S.B.2    Kuhlbrodt, K.3    Hennings, J.C.4    Ericson, J.5    Sander, M.6
  • 11
    • 2542484345 scopus 로고    scopus 로고
    • The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic b-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1
    • Iype, T., Taylor, D.G., Ziesmann, S.M., Garmey, J.C., Watada, H., and Mirmira, R.G. (2004). The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic b-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. Mol. Endocrinol. 18, 1363-1375.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 1363-1375
    • Iype, T.1    Taylor, D.G.2    Ziesmann, S.M.3    Garmey, J.C.4    Watada, H.5    Mirmira, R.G.6
  • 12
    • 33847217554 scopus 로고    scopus 로고
    • Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
    • Johansson, K.A., Dursun, U., Jordan, N., Gu, G., Beermann, F., Gradwohl, G., and Grapin-Botton, A. (2007). Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev. Cell 12, 457-465.
    • (2007) Dev. Cell , vol.12 , pp. 457-465
    • Johansson, K.A.1    Dursun, U.2    Jordan, N.3    Gu, G.4    Beermann, F.5    Gradwohl, G.6    Grapin-Botton, A.7
  • 13
    • 0032716367 scopus 로고    scopus 로고
    • Cloning and DNA-binding properties of the rat pancreatic b-cell-specific factor Nkx6.1
    • Jorgensen, M.C., Vestergard Petersen, H., Ericson, J., Madsen, O.D., and Serup, P. (1999). Cloning and DNA-binding properties of the rat pancreatic b-cell-specific factor Nkx6.1. FEBS Lett. 461, 287-294.
    • (1999) FEBS Lett. , vol.461 , pp. 287-294
    • Jorgensen, M.C.1    Vestergard Petersen, H.2    Ericson, J.3    Madsen, O.D.4    Serup, P.5
  • 14
    • 0029737816 scopus 로고    scopus 로고
    • The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein
    • Krapp, A., Knofler, M., Frutiger, S., Hughes, G.J., Hagenbuchle, O., and Wellauer, P.K. (1996). The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J. 15, 4317-4329.
    • (1996) EMBO J. , vol.15 , pp. 4317-4329
    • Krapp, A.1    Knofler, M.2    Frutiger, S.3    Hughes, G.J.4    Hagenbuchle, O.5    Wellauer, P.K.6
  • 16
    • 35348985382 scopus 로고    scopus 로고
    • Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex
    • Masui, T., Long, Q., Beres, T.M., Magnuson, M.A., and MacDonald, R.J. (2007). Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev. 21, 2629-2643.
    • (2007) Genes Dev. , vol.21 , pp. 2629-2643
    • Masui, T.1    Long, Q.2    Beres, T.M.3    Magnuson, M.A.4    MacDonald, R.J.5
  • 17
    • 50249106419 scopus 로고    scopus 로고
    • Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood
    • Masui, T., Swift, G.H., Hale, M.A., Meredith, D.M., Johnson, J.E., and Macdonald, R.J. (2008). Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood. Mol. Cell. Biol. 28, 5458-5468.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 5458-5468
    • Masui, T.1    Swift, G.H.2    Hale, M.A.3    Meredith, D.M.4    Johnson, J.E.5    Macdonald, R.J.6
  • 18
    • 0034640429 scopus 로고    scopus 로고
    • b-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains
    • Mirmira, R.G., Watada, H., and German, M.S. (2000). b-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains. J. Biol. Chem. 275, 14743-14751.
    • (2000) J. Biol. Chem. , vol.275 , pp. 14743-14751
    • Mirmira, R.G.1    Watada, H.2    German, M.S.3
  • 19
    • 0035937415 scopus 로고    scopus 로고
    • Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube
    • Muhr, J., Andersson, E., Persson, M., Jessell, T.M., and Ericson, J. (2001). Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube. Cell 104, 861-873.
    • (2001) Cell , vol.104 , pp. 861-873
    • Muhr, J.1    Andersson, E.2    Persson, M.3    Jessell, T.M.4    Ericson, J.5
  • 20
    • 0344736673 scopus 로고    scopus 로고
    • Notch signaling controls multiple steps of pancreatic differentiation
    • Murtaugh, L.C., Stanger, B.Z., Kwan, K.M., and Melton, D.A. (2003). Notch signaling controls multiple steps of pancreatic differentiation. Proc. Natl. Acad. Sci. USA 100, 14920-14925.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 14920-14925
    • Murtaugh, L.C.1    Stanger, B.Z.2    Kwan, K.M.3    Melton, D.A.4
  • 21
    • 34447521981 scopus 로고    scopus 로고
    • The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting b-cell fate specification in Pdx1+ pancreatic progenitor cells
    • Nelson, S.B., Schaffer, A.E., and Sander, M. (2007). The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting b-cell fate specification in Pdx1+ pancreatic progenitor cells. Development 134, 2491-2500.
    • (2007) Development , vol.134 , pp. 2491-2500
    • Nelson, S.B.1    Schaffer, A.E.2    Sander, M.3
  • 22
    • 0034488835 scopus 로고    scopus 로고
    • Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision
    • Novak, A., Guo, C., Yang, W., Nagy, A., and Lobe, C.G. (2000). Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis 28, 147-155.
    • (2000) Genesis , vol.28 , pp. 147-155
    • Novak, A.1    Guo, C.2    Yang, W.3    Nagy, A.4    Lobe, C.G.5
  • 23
    • 34249880105 scopus 로고    scopus 로고
    • Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination
    • Olguin, H.C., Yang, Z., Tapscott, S.J., and Olwin, B.B. (2007). Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination. J. Cell Biol. 177, 769-779.
    • (2007) J. Cell Biol. , vol.177 , pp. 769-779
    • Olguin, H.C.1    Yang, Z.2    Tapscott, S.J.3    Olwin, B.B.4
  • 26
    • 0033844629 scopus 로고    scopus 로고
    • Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates
    • Sander, M., Paydar, S., Ericson, J., Briscoe, J., Berber, E., German, M., Jessell, T.M., and Rubenstein, J.L. (2000a). Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates. Genes Dev. 14, 2134-2139.
    • (2000) Genes Dev. , vol.14 , pp. 2134-2139
    • Sander, M.1    Paydar, S.2    Ericson, J.3    Briscoe, J.4    Berber, E.5    German, M.6    Jessell, T.M.7    Rubenstein, J.L.8
  • 29
    • 53649102798 scopus 로고    scopus 로고
    • A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
    • Seymour, P.A., Freude, K.K., Dubois, C.L., Shih, H.P., Patel, N.A., and Sander, M. (2008). A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev. Biol. 323, 19-30.
    • (2008) Dev. Biol. , vol.323 , pp. 19-30
    • Seymour, P.A.1    Freude, K.K.2    Dubois, C.L.3    Shih, H.P.4    Patel, N.A.5    Sander, M.6
  • 31
    • 0035855712 scopus 로고    scopus 로고
    • Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification
    • Vallstedt, A., Muhr, J., Pattyn, A., Pierani, A., Mendelsohn, M., Sander, M., Jessell, T.M., and Ericson, J. (2001). Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification. Neuron 31, 743-755.
    • (2001) Neuron , vol.31 , pp. 743-755
    • Vallstedt, A.1    Muhr, J.2    Pattyn, A.3    Pierani, A.4    Mendelsohn, M.5    Sander, M.6    Jessell, T.M.7    Ericson, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.