메뉴 건너뛰기




Volumn 8, Issue 6, 2013, Pages

Pancreatic α-Cell Specific Deletion of Mouse Arx Leads to α-Cell Identity Loss

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; GLUCOSE TRANSPORTER 2; INSULIN; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1;

EID: 84878983251     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066214     Document Type: Article
Times cited : (69)

References (27)
  • 3
    • 79961187994 scopus 로고    scopus 로고
    • Transcriptional regulation of alpha-cell differentiation
    • Bramswig NC, Kaestner KH, (2011) Transcriptional regulation of alpha-cell differentiation. Diabetes Obes Metab 13Suppl 1: 13-20.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 13-20
    • Bramswig, N.C.1    Kaestner, K.H.2
  • 4
    • 75749108616 scopus 로고    scopus 로고
    • Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis
    • Juhl K, Bonner-Weir S, Sharma A, (2010) Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis. Current opinion in organ transplantation 15: 79-85.
    • (2010) Current Opinion in Organ Transplantation , vol.15 , pp. 79-85
    • Juhl, K.1    Bonner-Weir, S.2    Sharma, A.3
  • 6
    • 77951611220 scopus 로고    scopus 로고
    • Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
    • Thorel F, Nepote V, Avril I, Kohno K, Desgraz R, et al. (2010) Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss. Nature 464: 1149-1154.
    • (2010) Nature , vol.464 , pp. 1149-1154
    • Thorel, F.1    Nepote, V.2    Avril, I.3    Kohno, K.4    Desgraz, R.5
  • 7
    • 68149162957 scopus 로고    scopus 로고
    • The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells
    • Collombat P, Xu X, Ravassard P, Sosa-Pineda B, Dussaud S, et al. (2009) The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells. Cell 138: 449-462.
    • (2009) Cell , vol.138 , pp. 449-462
    • Collombat, P.1    Xu, X.2    Ravassard, P.3    Sosa-Pineda, B.4    Dussaud, S.5
  • 8
    • 84860410786 scopus 로고    scopus 로고
    • Context-specific alpha- to-beta-cell reprogramming by forced Pdx1 expression
    • Yang YP, Thorel F, Boyer DF, Herrera PL, Wright CV, (2011) Context-specific alpha- to-beta-cell reprogramming by forced Pdx1 expression. Genes Dev 25: 1680-1685.
    • (2011) Genes Dev , vol.25 , pp. 1680-1685
    • Yang, Y.P.1    Thorel, F.2    Boyer, D.F.3    Herrera, P.L.4    Wright, C.V.5
  • 9
    • 80053580232 scopus 로고    scopus 로고
    • Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression
    • Mastracci TL, Wilcox CL, Arnes L, Panea C, Golden JA, et al. (2011) Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol.
    • (2011) Dev Biol
    • Mastracci, T.L.1    Wilcox, C.L.2    Arnes, L.3    Panea, C.4    Golden, J.A.5
  • 11
    • 34147092649 scopus 로고    scopus 로고
    • Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression
    • Collombat P, Hecksher-Sorensen J, Krull J, Berger J, Riedel D, et al. (2007) Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression. J Clin Invest 117: 961-970.
    • (2007) J Clin Invest , vol.117 , pp. 961-970
    • Collombat, P.1    Hecksher-Sorensen, J.2    Krull, J.3    Berger, J.4    Riedel, D.5
  • 12
    • 77954980506 scopus 로고    scopus 로고
    • Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice
    • Hancock AS, Du A, Liu J, Miller M, May CL, (2010) Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice. Mol Endocrinol 24: 1605-1614.
    • (2010) Mol Endocrinol , vol.24 , pp. 1605-1614
    • Hancock, A.S.1    Du, A.2    Liu, J.3    Miller, M.4    May, C.L.5
  • 13
    • 77957320355 scopus 로고    scopus 로고
    • Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation
    • Itoh M, Takizawa Y, Hanai S, Okazaki S, Miyata R, et al. (2010) Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation. Differentiation 80: 118-122.
    • (2010) Differentiation , vol.80 , pp. 118-122
    • Itoh, M.1    Takizawa, Y.2    Hanai, S.3    Okazaki, S.4    Miyata, R.5
  • 14
    • 34548127883 scopus 로고    scopus 로고
    • The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells
    • Quoix N, Cheng-Xue R, Guiot Y, Herrera PL, Henquin JC, et al. (2007) The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells. FEBS letters 581: 4235-4240.
    • (2007) FEBS Letters , vol.581 , pp. 4235-4240
    • Quoix, N.1    Cheng-Xue, R.2    Guiot, Y.3    Herrera, P.L.4    Henquin, J.C.5
  • 15
    • 56049110230 scopus 로고    scopus 로고
    • Identification of Arx transcriptional targets in the developing basal forebrain
    • Fulp CT, Cho G, Marsh ED, Nasrallah IM, Labosky PA, et al. (2008) Identification of Arx transcriptional targets in the developing basal forebrain. Hum Mol Genet 17: 3740-3760.
    • (2008) Hum Mol Genet , vol.17 , pp. 3740-3760
    • Fulp, C.T.1    Cho, G.2    Marsh, E.D.3    Nasrallah, I.M.4    Labosky, P.A.5
  • 16
    • 0034121735 scopus 로고    scopus 로고
    • Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
    • Herrera PL, (2000) Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 127: 2317-2322.
    • (2000) Development , vol.127 , pp. 2317-2322
    • Herrera, P.L.1
  • 18
    • 0037090881 scopus 로고    scopus 로고
    • Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse
    • Hayashi S, McMahon AP, (2002) Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol 244: 305-318.
    • (2002) Dev Biol , vol.244 , pp. 305-318
    • Hayashi, S.1    McMahon, A.P.2
  • 19
    • 77951840060 scopus 로고    scopus 로고
    • Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development
    • Lu J, Herrera PL, Carreira C, Bonnavion R, Seigne C, et al. (2010) Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development. Gastroenterology 138: 1954-1965.
    • (2010) Gastroenterology , vol.138 , pp. 1954-1965
    • Lu, J.1    Herrera, P.L.2    Carreira, C.3    Bonnavion, R.4    Seigne, C.5
  • 20
    • 36549075522 scopus 로고    scopus 로고
    • Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells
    • Chao CS, Loomis ZL, Lee JE, Sussel L, (2007) Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol 312: 523-532.
    • (2007) Dev Biol , vol.312 , pp. 523-532
    • Chao, C.S.1    Loomis, Z.L.2    Lee, J.E.3    Sussel, L.4
  • 22
    • 0031843386 scopus 로고    scopus 로고
    • Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
    • Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, et al. (1998) Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 125: 2213-2221.
    • (1998) Development , vol.125 , pp. 2213-2221
    • Sussel, L.1    Kalamaras, J.2    Hartigan-O'Connor, D.J.3    Meneses, J.J.4    Pedersen, R.A.5
  • 23
    • 23144432613 scopus 로고    scopus 로고
    • The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas
    • Collombat P, Hecksher-Sorensen J, Broccoli V, Krull J, Ponte I, et al. (2005) The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas. Development 132: 2969-2980.
    • (2005) Development , vol.132 , pp. 2969-2980
    • Collombat, P.1    Hecksher-Sorensen, J.2    Broccoli, V.3    Krull, J.4    Ponte, I.5
  • 25
    • 79960081993 scopus 로고    scopus 로고
    • beta-Cell replication and islet neogenesis following partial pancreatectomy
    • Lee SH, Hao E, Levine F, (2011) beta-Cell replication and islet neogenesis following partial pancreatectomy. Islets 3: 188-195.
    • (2011) Islets , vol.3 , pp. 188-195
    • Lee, S.H.1    Hao, E.2    Levine, F.3
  • 26
    • 77956004353 scopus 로고    scopus 로고
    • Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats
    • Li WC, Rukstalis JM, Nishimura W, Tchipashvili V, Habener JF, et al. (2010) Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats. Journal of cell science 123: 2792-2802.
    • (2010) Journal of Cell Science , vol.123 , pp. 2792-2802
    • Li, W.C.1    Rukstalis, J.M.2    Nishimura, W.3    Tchipashvili, V.4    Habener, J.F.5
  • 27
    • 84859435577 scopus 로고    scopus 로고
    • Arx is required for normal enteroendocrine cell development in mice and humans
    • Du A, McCracken KW, Walp ER, Terry NA, Klein TJ, et al. (2012) Arx is required for normal enteroendocrine cell development in mice and humans. Developmental biology 365: 175-188.
    • (2012) Developmental Biology , vol.365 , pp. 175-188
    • Du, A.1    McCracken, K.W.2    Walp, E.R.3    Terry, N.A.4    Klein, T.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.