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Volumn 67, Issue 1, 2015, Pages 27-42

Chemopreventive and therapeutic potential of "Naringenin," a flavanone present in citrus fruits

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; NARINGENIN; SELECTIVE ESTROGEN RECEPTOR MODULATOR; ANTINEOPLASTIC AGENT; ANTIOXIDANT; FLAVANONE DERIVATIVE;

EID: 84920506588     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2015.976320     Document Type: Article
Times cited : (111)

References (148)
  • 1
    • 84872682242 scopus 로고    scopus 로고
    • Phytochemicals and cancer risk: A review of the epidemiological evidence
    • Miller PE and Snyder DC: Phytochemicals and cancer risk: a review of the epidemiological evidence. Nutrition and Clinical Practice 27, 599-561, 2012.
    • (2012) Nutrition and Clinical Practice , vol.27 , pp. 599-561
    • Miller, P.E.1    Snyder, D.C.2
  • 7
    • 33748529250 scopus 로고    scopus 로고
    • Effects of ascorbic acid on impaired vascular reactivity in aortas isolated from age-matched hypertensive and diabetic rats
    • Ajay M and Mustafa MR: Effects of ascorbic acid on impaired vascular reactivity in aortas isolated from age-matched hypertensive and diabetic rats. Vascular Pharmacology 45, 127-133, 2006.
    • (2006) Vascular Pharmacology , vol.45 , pp. 127-133
    • Ajay, M.1    Mustafa, M.R.2
  • 8
    • 37549056617 scopus 로고    scopus 로고
    • Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT i modification
    • Aoi W, Naito Y, Takanami Y, Ishii T, Kawai Y, et al.: Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification. Biochemical and Biophysical Research Communications 366, 892-897, 2008.
    • (2008) Biochemical and Biophysical Research Communications , vol.366 , pp. 892-897
    • Aoi, W.1    Naito, Y.2    Takanami, Y.3    Ishii, T.4    Kawai, Y.5
  • 9
    • 20444409147 scopus 로고    scopus 로고
    • Bioactivity and protective effects of natural carotenoids
    • Stahl W and Sies H: Bioactivity and protective effects of natural carotenoids. Biochimica et Biophysica Acta 1740(2), 101-10, 2005.
    • (2005) Biochimica et Biophysica Acta , vol.1740 , Issue.2 , pp. 101-110
    • Stahl, W.1    Sies, H.2
  • 10
    • 83055160833 scopus 로고    scopus 로고
    • A new antifungal coumarin from Clausena excavate
    • Kumar R, Saha A, and Saha D: A new antifungal coumarin from Clausena excavate. Fitoterapia 83(1), 230-233, 2012.
    • (2012) Fitoterapia , vol.83 , Issue.1 , pp. 230-233
    • Kumar, R.1    Saha, A.2    Saha, D.3
  • 11
    • 79956315031 scopus 로고    scopus 로고
    • Poly (lactide-co-glycolide) acid nanoencapsulation of a synthetic coumarin: Cytotoxicity and bio-distribution in mice, in cancer cell line and interaction with calf thymus DNA as target
    • Bhattacharyya SS, Paul S, De A, Das D, Samadder A, et al.: Poly (lactide-co-glycolide) acid nanoencapsulation of a synthetic coumarin: Cytotoxicity and bio-distribution in mice, in cancer cell line and interaction with calf thymus DNA as target. Toxicology and Applied Pharmacology 253, 270-281, 2011.
    • (2011) Toxicology and Applied Pharmacology , vol.253 , pp. 270-281
    • Bhattacharyya, S.S.1    Paul, S.2    De A Das, D.3    Samadder, A.4
  • 12
    • 0028116672 scopus 로고
    • Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and oxidation ferrous iron
    • Reddy AC and Lokesh BR: Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and oxidation ferrous iron. Molecular Cell Biochemistry 137, 1-8, 1994.
    • (1994) Molecular Cell Biochemistry , vol.137 , pp. 1-8
    • Reddy, A.C.1    Lokesh, B.R.2
  • 13
    • 55949117806 scopus 로고    scopus 로고
    • Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
    • Aggarwal BB and Harikumar KB: Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. The International Journal of Biochemistry & Cell Biology 41, 40-59, 2009.
    • (2009) The International Journal of Biochemistry & Cell Biology , vol.41 , pp. 40-59
    • Aggarwal, B.B.1    Harikumar, K.B.2
  • 14
    • 77954955441 scopus 로고    scopus 로고
    • Anti-inflammatory effects of black rice, cyanidin-3-O-b-D-glycoside, and its metabolites, cyanidin and protocatechuic acid
    • Min SW, Ryu SN, and Kim DH: Anti-inflammatory effects of black rice, cyanidin-3-O-b-D-glycoside, and its metabolites, cyanidin and protocatechuic acid. International Immunopharmacology 10, 959-966, 2010.
    • (2010) International Immunopharmacology , vol.10 , pp. 959-966
    • Min, S.W.1    Ryu, S.N.2    Kim, D.H.3
  • 15
    • 77955845051 scopus 로고    scopus 로고
    • Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARg transcriptional activity
    • Cho KW, Lee OH, Banz WJ, Moustaid-Moussa N, Shay NF, et al.: Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARg transcriptional activity. Journal of Nutritional Biochemistry 21, 841-847, 2010.
    • (2010) Journal of Nutritional Biochemistry , vol.21 , pp. 841-847
    • Cho, K.W.1    Lee, O.H.2    Banz, W.J.3    Moustaid-Moussa, N.4    Shay, N.F.5
  • 16
    • 48649083102 scopus 로고    scopus 로고
    • Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells
    • Choi EJ and Kim GH: Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells. Phytomedicine 15, 683-690, 2008.
    • (2008) Phytomedicine , vol.15 , pp. 683-690
    • Choi, E.J.1    Kim, G.H.2
  • 17
    • 70350205594 scopus 로고    scopus 로고
    • Eugenol protects nicotine-induced superoxide mediated oxidative damage in murine peritoneal macrophages in vitro
    • Kar Mahapatra S, Chakraborty SP, Majumdar S, Bag BG, and Roy S: Eugenol protects nicotine-induced superoxide mediated oxidative damage in murine peritoneal macrophages in vitro. European Journal of Pharmacology 623, 132-140, 2009.
    • (2009) European Journal of Pharmacology , vol.623 , pp. 132-140
    • Kar Mahapatra, S.1    Chakraborty, S.P.2    Majumdar, S.3    Bag, B.G.4    Roy, S.5
  • 18
    • 84875582274 scopus 로고    scopus 로고
    • Geraniol attenuates 12-O-Tetradecanoylphorbol-13-Acetate (TPA)-induced oxidative stress and inflammation in mouse skin: Possible role of p38 MAP Kinase and NF-kB
    • Khan AQ, Khan R, Qamar W, Lateef A, Rehman MU, et al.: Geraniol attenuates 12-O-Tetradecanoylphorbol-13-Acetate (TPA)-induced oxidative stress and inflammation in mouse skin: Possible role of p38 MAP Kinase and NF-kB. Experimental and Molecular Pathology 94, 419-429, 2013.
    • (2013) Experimental and Molecular Pathology , vol.94 , pp. 419-429
    • Khan, A.Q.1    Khan, R.2    Qamar, W.3    Lateef, A.4    Rehman, M.U.5
  • 19
    • 78651069319 scopus 로고    scopus 로고
    • Inactivation of Nuclear Factor-kB by citrus flavanone hesperidin contributes to apoptosis and chemo-sensitizing effect in Ramos cells
    • Nazari M, Ghorbani A, Hekmat-Doost A, Jeddi-Tehrani M, and Zand H: Inactivation of Nuclear Factor-kB by citrus flavanone hesperidin contributes to apoptosis and chemo-sensitizing effect in Ramos cells. European Journal of Pharmacology 650, 526-533, 2011.
    • (2011) European Journal of Pharmacology , vol.650 , pp. 526-533
    • Nazari, M.1    Ghorbani, A.2    Hekmat-Doost, A.3    Jeddi-Tehrani, M.4    Zand, H.5
  • 21
    • 65049086069 scopus 로고    scopus 로고
    • Protective effect of hydroxytyrosol against acrylamide-induced cytotoxicity and DNA damage in HepG2 cells
    • Zhang X, Cao J, Jiang L, Geng C, and Zhong L: Protective effect of hydroxytyrosol against acrylamide-induced cytotoxicity and DNA damage in HepG2 cells. Mutation Research 664(1-2), 64-68, 2009.
    • (2009) Mutation Research , vol.664 , Issue.1-2 , pp. 64-68
    • Zhang, X.1    Cao, J.2    Jiang, L.3    Geng, C.4    Zhong, L.5
  • 22
    • 80052776095 scopus 로고    scopus 로고
    • Hydroxytyrosol glucuronides protect renal tubular epithelial cells against H2O2 induced oxidative damage
    • Deiana M, Incani A, Rosa A, Atzeri A, Loru D, et al.: Hydroxytyrosol glucuronides protect renal tubular epithelial cells against H2O2 induced oxidative damage. Chemico-Biological Interactions 193, 232-239, 2011.
    • (2011) Chemico-Biological Interactions , vol.193 , pp. 232-239
    • Deiana, M.1    Incani, A.2    Rosa, A.3    Atzeri, A.4    Loru, D.5
  • 23
    • 67651111871 scopus 로고    scopus 로고
    • Protective effects of kaempferol against endothelial damage by an improvement in nitric oxide production and a decrease in asymmetric dimethylarginine level
    • Xiao HB, Jun-Fang, Lu XY, Chen XJ, Chao-Tan, et al.: Protective effects of kaempferol against endothelial damage by an improvement in nitric oxide production and a decrease in asymmetric dimethylarginine level. European Journal of Pharmacology 616(1-3), 213-222, 2009.
    • (2009) European Journal of Pharmacology , vol.616 , Issue.1-3 , pp. 213-222
    • Xiao, H.B.1    Jun-Fang Lu, X.Y.2    Chen, X.J.3    Chao-Tan4
  • 24
    • 67349252446 scopus 로고    scopus 로고
    • Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells
    • Kang GY, Lee ER, Kim JH, Jung JW, Lim J, et al.: Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells. European Journal of Pharmacology 611(1-3), 17-21, 2009.
    • (2009) European Journal of Pharmacology , vol.611 , Issue.1-3 , pp. 17-21
    • Kang, G.Y.1    Lee, E.R.2    Kim, J.H.3    Jung, J.W.4    Lim, J.5
  • 25
    • 84858008814 scopus 로고    scopus 로고
    • A bioactivity guided study on the antidiabetic activity of Juniperus oxycedrus subsp Oxycedrus L leaves
    • Orhan N, Aslan M, Demirci B, and Ergun F: A bioactivity guided study on the antidiabetic activity of Juniperus oxycedrus subsp. Oxycedrus L. leaves. Journal of Ethnopharmacology 140, 409-415, 2012.
    • (2012) Journal of Ethnopharmacology , vol.140 , pp. 409-415
    • Orhan, N.1    Aslan, M.2    Demirci, B.3    Ergun, F.4
  • 26
    • 0032078179 scopus 로고    scopus 로고
    • Modulation of macrophage cytokine production by conjugated linoleic acids is influenced by the dietary n-6:n-3 fatty acid ratio
    • Turek JJ, Li Y, Schoenlein IA, Allen KGD, and Watkins BA: Modulation of macrophage cytokine production by conjugated linoleic acids is influenced by the dietary n-6:n-3 fatty acid ratio. Nutritional Biochemistry 9, 258-266, 1998.
    • (1998) Nutritional Biochemistry , vol.9 , pp. 258-266
    • Turek, J.J.1    Li, Y.2    Schoenlein, I.A.3    Allen, K.G.D.4    Watkins, B.A.5
  • 27
    • 0019941886 scopus 로고
    • First proof that vitamin e is major lipid-soluble, chain-breaking antioxidant in human blood plasma
    • Burton GW, Joyce A, and Ingold KU: First proof that vitamin E is major lipid-soluble, chain-breaking antioxidant in human blood plasma. The Lancet 2, 327, 1982.
    • (1982) The Lancet , vol.2 , pp. 327
    • Burton, G.W.1    Joyce, A.2    Ingold, K.U.3
  • 33
    • 0033863355 scopus 로고    scopus 로고
    • Dietary intake and bioavailability of polyphenols
    • Suppl
    • Scalbert A and Williamson G: Dietary intake and bioavailability of polyphenols. Journal of Nutrition 130(8S Suppl), 2073S-2085S, 2000.
    • (2000) Journal of Nutrition , vol.130 , pp. 2073S-2085S
    • Scalbert, A.1    Williamson, G.2
  • 34
    • 84857021782 scopus 로고    scopus 로고
    • Toxicological aspects of the use of phenolic compounds in disease prevention
    • Kyselova Z: Toxicological aspects of the use of phenolic compounds in disease prevention. Interdisciplinary Toxicology 4, 173-183, 2011.
    • (2011) Interdisciplinary Toxicology , vol.4 , pp. 173-183
    • Kyselova, Z.1
  • 38
    • 79953860147 scopus 로고    scopus 로고
    • Properties of chalconargenin and rutin isolated from cherry tomatoes
    • Slimestad R and Verheul M: Properties of chalconargenin and rutin isolated from cherry tomatoes. Journal of Agriculture Food Chemistry 59, 3180-3185, 2011.
    • (2011) Journal of Agriculture Food Chemistry , vol.59 , pp. 3180-3185
    • Slimestad, R.1    Verheul, M.2
  • 39
    • 40549101349 scopus 로고    scopus 로고
    • Anticarcinogenic compounds in the Uzbek medicinal plant, Helichrysum Maracandicum
    • Yagura T, Motomiya T, Ito M, Honda G, Lida A, et al.: Anticarcinogenic compounds in the Uzbek medicinal plant, Helichrysum Maracandicum. J Nature Medicine 62, 174-178, 2008.
    • (2008) J Nature Medicine , vol.62 , pp. 174-178
    • Yagura, T.1    Motomiya, T.2    Ito, M.3    Honda, G.4    Lida, A.5
  • 40
    • 77949686197 scopus 로고    scopus 로고
    • Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells
    • Iwamura C, Shinoda K, Yoshimura M, Watanabe Y, Obata A, et al.: Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells. Allergology International 59, 67-73, 2010.
    • (2010) Allergology International , vol.59 , pp. 67-73
    • Iwamura, C.1    Shinoda, K.2    Yoshimura, M.3    Watanabe, Y.4    Obata, A.5
  • 42
    • 84871301162 scopus 로고    scopus 로고
    • Protective effects of fermented citrus unshiu peel extract against ultraviolet-A-induced photoageing in human dermal fibroblasts
    • Bae JT, Ko HJ, Kim GB, Pyo HB, and Lee GS: Protective effects of fermented citrus unshiu peel extract against ultraviolet-A-induced photoageing in human dermal fibroblasts. Phytotherapy Research 26, 1851-1856, 2012.
    • (2012) Phytotherapy Research , vol.26 , pp. 1851-1856
    • Bae, J.T.1    Ko, H.J.2    Kim, G.B.3    Pyo, H.B.4    Lee, G.S.5
  • 43
    • 84865447939 scopus 로고    scopus 로고
    • Narirutin Fraction from citrus peels attenuates LPS-stimulated inflammatory response through inhibition of NF-kB and MAPKs activation
    • Ha SK, Park HY, Eom H, Kim Y, and Choi I: Narirutin Fraction from citrus peels attenuates LPS-stimulated inflammatory response through inhibition of NF-kB and MAPKs activation. Journal of Food and Chemical Toxicology 50, 3498-3504, 2012.
    • (2012) Journal of Food and Chemical Toxicology , vol.50 , pp. 3498-3504
    • Ha, S.K.1    Park, H.Y.2    Eom, H.3    Kim, Y.4    Choi, I.5
  • 44
    • 84863143923 scopus 로고    scopus 로고
    • Toxicokenitics of Naringin and its metabolite Naringenin after 180-day repeated oral administration in beagle dogs assayed by a rapid resolution liquid chromatography/ tandem mass spectrometric method
    • Yang CP, Liu MH, Zou W, Guan XL, Lia L, et al.: Toxicokenitics of Naringin and its metabolite Naringenin after 180-day repeated oral administration in beagle dogs assayed by a rapid resolution liquid chromatography/ tandem mass spectrometric method. Journal of Asian Natural Products Research 14, 68-75, 2012.
    • (2012) Journal of Asian Natural Products Research , vol.14 , pp. 68-75
    • Yang, C.P.1    Liu, M.H.2    Zou, W.3    Guan, X.L.4    Lia, L.5
  • 45
    • 77749295765 scopus 로고    scopus 로고
    • Flavanone and diphenylpropane Glycosides and glycosidic acyl esters from viscum articulatum
    • Kuo YJ, yang YC, Zhan LJ, Wu MD, Kuo LM, et al.: Flavanone and diphenylpropane Glycosides and glycosidic acyl esters from viscum articulatum. Journal of Natural Products 73, 109-114, 2010.
    • (2010) Journal of Natural Products , vol.73 , pp. 109-114
    • Kuo, Y.J.1    Yang, Y.C.2    Zhan, L.J.3    Wu, M.D.4    Kuo, L.M.5
  • 46
    • 38549181533 scopus 로고    scopus 로고
    • Protective effects of naringenin-7-O-glucoside on doxorubicin-induced apoptosis in H9C2 cells
    • Han X, Ren D, Fan P, Shen T, and Lou H: Protective effects of naringenin-7-O-glucoside on doxorubicin-induced apoptosis in H9C2 cells. European Journal of Pharmacology 581(1-2), 47-53, 2008.
    • (2008) European Journal of Pharmacology , vol.581 , Issue.1-2 , pp. 47-53
    • Han, X.1    Ren, D.2    Fan, P.3    Shen, T.4    Lou, H.5
  • 47
    • 40249119157 scopus 로고    scopus 로고
    • Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induce a caspase-independent form of cell death
    • Delmulle L, Vanden Berghe T, Keukeleire DD, and Vandenabeele P: Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induce a caspase-independent form of cell death. Phytotherapy Research 22, 197-203, 2008.
    • (2008) Phytotherapy Research , vol.22 , pp. 197-203
    • Delmulle, L.1    Vanden Berghe, T.2    Keukeleire, D.D.3    Vandenabeele, P.4
  • 53
    • 84862908776 scopus 로고    scopus 로고
    • Apple flavonoid Phloretin inhibits Escherichia coli 0157: H7 bioflim formation and ameliorates colon inflammation in rats
    • Lee JH, Regmi SC, Kim JA, Cho MH, Yun H, et al.: Apple flavonoid Phloretin inhibits Escherichia coli 0157: H7 bioflim formation and ameliorates colon inflammation in rats. Infection and Immunity 79, 4819-4827, 2011.
    • (2011) Infection and Immunity , vol.79 , pp. 4819-4827
    • Lee, J.H.1    Regmi, S.C.2    Kim, J.A.3    Cho, M.H.4    Yun, H.5
  • 55
    • 75749127437 scopus 로고    scopus 로고
    • Inhibition of oxidation of aqueous emulsion of Omega-3 fatty acids and fish oil by Phloretin and phloridzin
    • Vasantha RHP and Yasmin A: Inhibition of oxidation of aqueous emulsion of Omega-3 fatty acids and fish oil by Phloretin and phloridzin. Molecules 15, 251-257, 2010.
    • (2010) Molecules , vol.15 , pp. 251-257
    • Vasantha, R.H.P.1    Yasmin, A.2
  • 56
    • 84862811845 scopus 로고    scopus 로고
    • Dual effects of Phloretin on aflatoxin B1 metabolism: Activation and detoxification of aflatoxin B1
    • Gao SS, Chen XY, Zhu RZ, Choi BM, Kim SJ, et al.: Dual effects of Phloretin on aflatoxin B1 metabolism: activation and detoxification of aflatoxin B1. Biofactors 38, 34-43, 2012.
    • (2012) Biofactors , vol.38 , pp. 34-43
    • Gao, S.S.1    Chen, X.Y.2    Zhu, R.Z.3    Choi, B.M.4    Kim, S.J.5
  • 57
    • 79957606096 scopus 로고    scopus 로고
    • The antiproliferative effects of dietary fiber phenolic compounds Ferulic acid and p-Coumaric acid on the cell cycle of CaCo-2 cells
    • Janicke B, Hegardt C, Krogh M, Onning G, Akesson B, et al.: The antiproliferative effects of dietary fiber phenolic compounds Ferulic acid and p-Coumaric acid on the cell cycle of CaCo-2 cells. Nutrition and Cancer 63, 611-622, 2011.
    • (2011) Nutrition and Cancer , vol.63 , pp. 611-622
    • Janicke, B.1    Hegardt, C.2    Krogh, M.3    Onning, G.4    Akesson, B.5
  • 58
    • 33845539126 scopus 로고    scopus 로고
    • Subtle side-chain modification of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptor alpha and beta
    • Roelens F, Heldring N, Dhooge W, Bengtsson M, Comhaire F, et al.: Subtle side-chain modification of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptor alpha and beta. Journal of Medicinal Chemistry 49, 7357-7365, 2006.
    • (2006) Journal of Medicinal Chemistry , vol.49 , pp. 7357-7365
    • Roelens, F.1    Heldring, N.2    Dhooge, W.3    Bengtsson, M.4    Comhaire, F.5
  • 60
    • 0036400016 scopus 로고    scopus 로고
    • Dietary flavonoids: Bioavailability, metabolic effects, and safety
    • Ross JA and Kasum CM: Dietary flavonoids: Bioavailability, metabolic effects, and safety. Annual Review of Nutrition 22, 19-34, 2002.
    • (2002) Annual Review of Nutrition , vol.22 , pp. 19-34
    • Ross, J.A.1    Kasum, C.M.2
  • 66
    • 77954273219 scopus 로고    scopus 로고
    • Preparation and physicochemical properties of the complex of naringenin with hydroxypropyl-b-cyclodextrin
    • Wen J, Liu B, Yuan E, Ma Y, Zhu Y: Preparation and physicochemical properties of the complex of naringenin with hydroxypropyl-b-cyclodextrin. Molecules 15, 4401-4407, 2010.
    • (2010) Molecules , vol.15 , pp. 4401-4407
    • Wen, J.1    Liu, B.2    Yuan, E.3    Ma, Y.4    Zhu, Y.5
  • 67
    • 79953748950 scopus 로고    scopus 로고
    • Enhancement of NGN bioavailability by complexation with hydroxypropyl-b-cyclodextrin
    • Shulman M, Cohen M, Soto-Gutierrez A, Yagi H, Wang H, et al.: Enhancement of NGN bioavailability by complexation with hydroxypropyl-b-cyclodextrin. PLoS ONE 6(4), 18033, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.4 , pp. 18033
    • Shulman, M.1    Cohen, M.2    Soto-Gutierrez, A.3    Yagi, H.4    Wang, H.5
  • 68
    • 61449086284 scopus 로고    scopus 로고
    • Naringenin-loaded nanoparticles improve the physicochemical properties and the hepatoprotective effect of naringenin in orally- administrated rats with CCl4-induced acute liver failure
    • Yen FL, Wu TH, Lin LT, Cham TM, and Lin CC: Naringenin-loaded nanoparticles improve the physicochemical properties and the hepatoprotective effect of naringenin in orally- administrated rats with CCl4-induced acute liver failure. Pharmaceutical Research 26, 893-902, 2009.
    • (2009) Pharmaceutical Research , vol.26 , pp. 893-902
    • Yen, F.L.1    Wu, T.H.2    Lin, L.T.3    Cham, T.M.4    Lin, C.C.5
  • 69
    • 83655191635 scopus 로고    scopus 로고
    • Enhanced anticancer activity of naringenin-loaded nanoparticles in human cervical (HeLa) cancer cells
    • Krishnakumar N, Sulfikkarali N, Rajendra Prasad N, and Karthikeyan S: Enhanced anticancer activity of naringenin-loaded nanoparticles in human cervical (HeLa) cancer cells. Biomed Prev Nutr 1, 223-231, 2011.
    • (2011) Biomed Prev Nutr , vol.1 , pp. 223-231
    • Krishnakumar, N.1    Sulfikkarali, N.2    Rajendra Prasad, N.3    Karthikeyan, S.4
  • 70
    • 84880114929 scopus 로고    scopus 로고
    • Chemopreventive efficacy of naringenin-loaded nanoparticles in 7,12-dimethylbenz( a)anthracene induced experimental oral carcinogenesis
    • Sulfikkarali N, Krishnakumar N, Manoharan S, and Nirmal RM: Chemopreventive efficacy of naringenin-loaded nanoparticles in 7,12-dimethylbenz( a)anthracene induced experimental oral carcinogenesis. Pathology and Oncology Research 19, 287-296, 2013.
    • (2013) Pathology and Oncology Research , vol.19 , pp. 287-296
    • Sulfikkarali, N.1    Krishnakumar, N.2    Manoharan, S.3    Nirmal, R.M.4
  • 71
    • 0029610477 scopus 로고
    • Review of the biology of quercetin and related bioflavonoids
    • Formica JV and Regelson W: Review of the biology of quercetin and related bioflavonoids. Food and Chemical Toxicology 33, 1061-1080, 1995.
    • (1995) Food and Chemical Toxicology , vol.33 , pp. 1061-1080
    • Formica, J.V.1    Regelson, W.2
  • 74
    • 0035150315 scopus 로고    scopus 로고
    • Plasma kinetics and urinary excretion of the flavanones NGN and hesperetin in humans after ingestion of orange juice and grapefruit juice
    • Erlund I, Meririnne E, Alfthan G, and Aro A: Plasma kinetics and urinary excretion of the flavanones NGN and hesperetin in humans after ingestion of orange juice and grapefruit juice. Journal of Nutrition 131, 235-241, 2001.
    • (2001) Journal of Nutrition , vol.131 , pp. 235-241
    • Erlund, I.1    Meririnne, E.2    Alfthan, G.3    Aro, A.4
  • 75
    • 0027510377 scopus 로고
    • Inhibitory effect of grapefruit juice and its bitter principal, Naringenin, on CYP1A2 dependent metabolism of caffeine in man
    • Fuhr U, Klittich K, and Staib AH: Inhibitory effect of grapefruit juice and its bitter principal, Naringenin, on CYP1A2 dependent metabolism of caffeine in man. British Journal of Clinical Pharmacology 35, 431-436, 1993.
    • (1993) British Journal of Clinical Pharmacology , vol.35 , pp. 431-436
    • Fuhr, U.1    Klittich, K.2    Staib, A.H.3
  • 77
    • 9744242794 scopus 로고    scopus 로고
    • Review-dietary flavonoids and cancer risk: Evidence from population based study
    • Neuhoser ML: Review-dietary flavonoids and cancer risk: Evidence from population based study. Nutrition and Cancer 50(1), 1-7, 2004.
    • (2004) Nutrition and Cancer , vol.50 , Issue.1 , pp. 1-7
    • Neuhoser, M.L.1
  • 78
    • 0029781370 scopus 로고    scopus 로고
    • Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices
    • So FV, Guthrie N, Chambers AF, Moussa M, and Carroll KK: Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices. Nutrition and Cancer 26, 167-181, 1996.
    • (1996) Nutrition and Cancer , vol.26 , pp. 167-181
    • So, F.V.1    Guthrie, N.2    Chambers, A.F.3    Moussa, M.4    Carroll, K.K.5
  • 79
    • 85027930668 scopus 로고    scopus 로고
    • The citrus flavanone Naringenin suppresses CYP1B1 transactivation through antagonizing xenobiotic-responsive element binding
    • Poon CH, Wong TY, Wang Y, Tsuchiya Y, Nakajima M, et al.: The citrus flavanone Naringenin suppresses CYP1B1 transactivation through antagonizing xenobiotic-responsive element binding. Molecular Nutrition 109, 1598-1605, 2013.
    • (2013) Molecular Nutrition , vol.109 , pp. 1598-1605
    • Poon, C.H.1    Wong, T.Y.2    Wang, Y.3    Tsuchiya, Y.4    Nakajima, M.5
  • 81
    • 38349087272 scopus 로고    scopus 로고
    • Naringenin reduces tumor size and weight lost in N-methyl-N'-nitro-Nnitrosoguanidine-induced gastric carcinogenesis in rats
    • Ekambaram G, Rajendran P, Magesh V, and Sakthisekaran D: Naringenin reduces tumor size and weight lost in N-methyl-N'-nitro-Nnitrosoguanidine-induced gastric carcinogenesis in rats. Nutrition Research 28, 106-112, 2008.
    • (2008) Nutrition Research , vol.28 , pp. 106-112
    • Ekambaram, G.1    Rajendran, P.2    Magesh, V.3    Sakthisekaran, D.4
  • 82
    • 84880332738 scopus 로고    scopus 로고
    • Attenuation of NDEA- induced hepatocarcinogenesis by the Naringenin in rats
    • Subramanian P and Arul D: Attenuation of NDEA- induced hepatocarcinogenesis by the Naringenin in rats. Cell Biochemistry and Function 31, 511-517, 2013.
    • (2013) Cell Biochemistry and Function , vol.31 , pp. 511-517
    • Subramanian, P.1    Arul, D.2
  • 83
    • 41049106041 scopus 로고    scopus 로고
    • Naringenin protects HaCaT human keratinocytes against UVB-induced apoptosis and enhances the removal of cyclobutane pyrimidine dimers from the genome
    • El-Mahdy MA, Zhu Q, Wang QE, Wani G, Patnaik S, et al.: Naringenin protects HaCaT human keratinocytes against UVB-induced apoptosis and enhances the removal of cyclobutane pyrimidine dimers from the genome. Photochemistry and Photobiology 84, 307-316, 2008.
    • (2008) Photochemistry and Photobiology , vol.84 , pp. 307-316
    • El-Mahdy, M.A.1    Zhu, Q.2    Wang, Q.E.3    Wani, G.4    Patnaik, S.5
  • 84
    • 0031792336 scopus 로고    scopus 로고
    • Influence of different penetration enhancers on in vitro skin permeation and in vivo photoprotective effect of flavonoids
    • Saija A, Tomaino A, Trombetta D, Giacchi M, Pasquale AD, et al.: Influence of different penetration enhancers on in vitro skin permeation and in vivo photoprotective effect of flavonoids. International Journal of Pharmaceutics 175, 85-94, 1998.
    • (1998) International Journal of Pharmaceutics , vol.175 , pp. 85-94
    • Saija, A.1    Tomaino, A.2    Trombetta, D.3    Giacchi, M.4    Pasquale, A.D.5
  • 85
    • 83455162466 scopus 로고    scopus 로고
    • Naringenin, a flavanone alters the tumorigenic features of C6 glioma cells
    • Sabarinathan D and Vanisree AJ: Naringenin, a flavanone alters the tumorigenic features of C6 glioma cells. Biomedicine & Preventive Nutrition 1, 19-24, 2011.
    • (2011) Biomedicine & Preventive Nutrition , vol.1 , pp. 19-24
    • Sabarinathan, D.1    Vanisree, A.J.2
  • 86
    • 84872332879 scopus 로고    scopus 로고
    • Neuroprotective effect of Naringenin is mediated through suppression of NF-kB signaling pathway in experimental stroke
    • Raza SS, Khan MM, Ahmad A, Ashafaq M, Islam F, et al.: Neuroprotective effect of Naringenin is mediated through suppression of NF-kB signaling pathway in experimental stroke. Journal of Neuroscience 230, 157-171, 2013.
    • (2013) Journal of Neuroscience , vol.230 , pp. 157-171
    • Raza, S.S.1    Khan, M.M.2    Ahmad, A.3    Ashafaq, M.4    Islam, F.5
  • 87
    • 36349037090 scopus 로고    scopus 로고
    • Rejection of metastatic 4T1 breast cancer by attenuation of Treg cells in combination with immune stimulation
    • Chen L, Huang TG, Meseck M, Mandeli J, Fallon J, et al.: Rejection of metastatic 4T1 breast cancer by attenuation of Treg cells in combination with immune stimulation. Molecular Therapy 15, 2194-2202, 2007.
    • (2007) Molecular Therapy , vol.15 , pp. 2194-2202
    • Chen, L.1    Huang, T.G.2    Meseck, M.3    Mandeli, J.4    Fallon, J.5
  • 88
    • 80053082680 scopus 로고    scopus 로고
    • Naringenin reduces lung metastasis in a breast cancer resection model
    • Qin L, Jin L, Lu L, Lu X, Zhang C, et al.: Naringenin reduces lung metastasis in a breast cancer resection model. Protein Cell 2, 507-516, 2011.
    • (2011) Protein Cell , vol.2 , pp. 507-516
    • Qin, L.1    Jin, L.2    Lu, L.3    Lu, X.4    Zhang, C.5
  • 89
    • 0030755148 scopus 로고    scopus 로고
    • Increased surgery-induced metastasis and suppressed natural killer cell activity during proestrus/estrus in rats
    • Page GG and Ben-Eliyahu S: Increased surgery-induced metastasis and suppressed natural killer cell activity during proestrus/estrus in rats. Breast Cancer Research and Treatment 45, 159-167, 1997.
    • (1997) Breast Cancer Research and Treatment , vol.45 , pp. 159-167
    • Page, G.G.1    Ben-Eliyahu, S.2
  • 90
    • 0022443560 scopus 로고
    • Depression of cellular-immunity after major injury-its association with post traumatic complications and its reversal with immunomodulation
    • Faist E, Kupper TS, Baker CC, Chaudry IH, Dwyer J, et al.: Depression of cellular-immunity after major injury-its association with post traumatic complications and its reversal with immunomodulation. Archives of Surgery-Chicago 121, 1000-1005, 1986.
    • (1986) Archives of Surgery-Chicago , vol.121 , pp. 1000-1005
    • Faist, E.1    Kupper, T.S.2    Baker, C.C.3    Chaudry, I.H.4    Dwyer, J.5
  • 92
    • 66149151048 scopus 로고    scopus 로고
    • Naringenin: A potential immunomodulator for inhibiting lung fibrosis and metastasis
    • Du G, Jin L, Han X, Song Z, Zhang H, et al.: Naringenin: a potential immunomodulator for inhibiting lung fibrosis and metastasis. Cancer Research 69, 3205-3212, 2009.
    • (2009) Cancer Research , vol.69 , pp. 3205-3212
    • Du, G.1    Jin, L.2    Han, X.3    Song, Z.4    Zhang, H.5
  • 93
    • 0037359775 scopus 로고    scopus 로고
    • The variable effect on proliferation of a colon cancer cell line by the citrus fruit flavonoid NGN
    • Frydoonfar HR, McGrath DR, and Spigelman AD: The variable effect on proliferation of a colon cancer cell line by the citrus fruit flavonoid NGN. Colorectal Disease 5, 149-152, 2003.
    • (2003) Colorectal Disease , vol.5 , pp. 149-152
    • Frydoonfar, H.R.1    McGrath, D.R.2    Spigelman, A.D.3
  • 94
    • 33745700890 scopus 로고    scopus 로고
    • Suppression of colon carcinogenesis by bioactive compounds in grapefruit
    • Vanamala J, Leonardi T, Patil BS, Taddeo SS, Murphy ME, et al.: Suppression of colon carcinogenesis by bioactive compounds in grapefruit. Carcinogenesis 27, 1257-1265, 2006.
    • (2006) Carcinogenesis , vol.27 , pp. 1257-1265
    • Vanamala, J.1    Leonardi, T.2    Patil, B.S.3    Taddeo, S.S.4    Murphy, M.E.5
  • 95
    • 84885191227 scopus 로고    scopus 로고
    • Naringenin (citrus flavonone) induces growth inhibition, cell cycle arrest and apoptosis in human hepatocellular carcinoma cells
    • Arul D and Subramanian P: Naringenin (citrus flavonone) induces growth inhibition, cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. Pathology and Oncology Research 19, 763-770, 2013.
    • (2013) Pathology and Oncology Research , vol.19 , pp. 763-770
    • Arul, D.1    Subramanian, P.2
  • 96
    • 80052664208 scopus 로고    scopus 로고
    • Recent advances in p53 research and cancer treatment
    • doi:10.1155/2011/978312
    • Suzuki K and Matsubara H: Recent advances in p53 research and cancer treatment. Journal of Biomedicine and Biotechnology 2011, 978312, 2011. doi:10.1155/2011/978312
    • (2011) Journal of Biomedicine and Biotechnology , vol.2011 , pp. 978312
    • Suzuki, K.1    Matsubara, H.2
  • 97
    • 80051761743 scopus 로고    scopus 로고
    • The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
    • Kelly PN and Strasser A: The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy. Cell Death and Differentiation 18, 1414-1424, 2011.
    • (2011) Cell Death and Differentiation , vol.18 , pp. 1414-1424
    • Kelly, P.N.1    Strasser, A.2
  • 99
    • 0035872426 scopus 로고    scopus 로고
    • Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal regulated kinase 2 activation
    • Ellenrieder V, Hendler SF, Boeck W, Seufferlein T, Menke A, et al.: Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal regulated kinase 2 activation. Cancer Research 61, 4222-4228, 2001.
    • (2001) Cancer Research , vol.61 , pp. 4222-4228
    • Ellenrieder, V.1    Hendler, S.F.2    Boeck, W.3    Seufferlein, T.4    Menke, A.5
  • 100
    • 79955147792 scopus 로고    scopus 로고
    • A single-molecule study of the inhibition effect of Naringenin on transforming growth factor-b ligand-receptor binding
    • Yang Y, Xu Y, Xia T, Chen F, Zhang C, et al.: A single-molecule study of the inhibition effect of Naringenin on transforming growth factor-b ligand-receptor binding. Chem Commun (Camb) 47, 5440-5442, 2011.
    • (2011) Chem Commun (Camb) , vol.47 , pp. 5440-5442
    • Yang, Y.1    Xu, Y.2    Xia, T.3    Chen, F.4    Zhang, C.5
  • 101
    • 32244440927 scopus 로고    scopus 로고
    • Smad3 specific inhibitor, naringenin, decreases the expression of extracellular matrix induced by TGF-beta1 in cultured rat hepatic stellate cells
    • Liu X, Wang W, Hu H, Tang N, Zhang C, et al.: Smad3 specific inhibitor, naringenin, decreases the expression of extracellular matrix induced by TGF-beta1 in cultured rat hepatic stellate cells. Pharmaceutical Research 23, 82-89, 2006.
    • (2006) Pharmaceutical Research , vol.23 , pp. 82-89
    • Liu, X.1    Wang, W.2    Hu, H.3    Tang, N.4    Zhang, C.5
  • 102
    • 67650999217 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer
    • Arumugam T, Ramachandran V, Fournier KF, Wang H, Marquis L, et al.: Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Research 69, 5820-5828, 2009.
    • (2009) Cancer Research , vol.69 , pp. 5820-5828
    • Arumugam, T.1    Ramachandran, V.2    Fournier, K.F.3    Wang, H.4    Marquis, L.5
  • 103
    • 84871591193 scopus 로고    scopus 로고
    • Naringenin decreases invasiveness and metastasis by inhibiting TGF-b-induced epithelial to mesenchymal transition in pancreatic cancer cells
    • Lou C, Zhang F, Yang M, Zhao J, Zeng W, et al.: Naringenin decreases invasiveness and metastasis by inhibiting TGF-b-induced epithelial to mesenchymal transition in pancreatic cancer cells. PLOS One 7(12), 50956, 2012.
    • (2012) PLOS One , vol.7 , Issue.12 , pp. 50956
    • Lou, C.1    Zhang, F.2    Yang, M.3    Zhao, J.4    Zeng, W.5
  • 105
    • 0037083978 scopus 로고    scopus 로고
    • The action of dietary phytochemicals quercetin, catechin, resveratrol and naringenin on estrogen-mediated gene expression
    • Ratna WN and Simonelli JA: The action of dietary phytochemicals quercetin, catechin, resveratrol and naringenin on estrogen-mediated gene expression. Life Sciences 70,1577-1589, 2002.
    • (2002) Life Sciences , vol.70 , pp. 1577-1589
    • Ratna, W.N.1    Simonelli, J.A.2
  • 107
    • 80255138218 scopus 로고    scopus 로고
    • Citrus flavanone Naringenin enhances melanogenesis through the activation of Wnt/b-catenin signalling in mouse melanoma cells
    • Huang YC, Yang CH, and Chiou YL: Citrus flavanone Naringenin enhances melanogenesis through the activation of Wnt/b-catenin signalling in mouse melanoma cells. Phytomedicine 18, 1244-1249, 2011.
    • (2011) Phytomedicine , vol.18 , pp. 1244-1249
    • Huang, Y.C.1    Yang, C.H.2    Chiou, Y.L.3
  • 108
    • 84863672993 scopus 로고    scopus 로고
    • Naringenin inhibits cell growth and migration in human breast cancer cell lines
    • Abstract)
    • Guerreiro S, Monteiro, R, Calhau C, Azevedo I, and Soares R: Naringenin inhibits cell growth and migration in human breast cancer cell lines. The FASEB Journal 21, 848.5, 2007 (Abstract).
    • (2007) The FASEB Journal , vol.21 , pp. 8485
    • Guerreiro, S.1    Monteiro, R.2    Calhau, C.3    Azevedo, I.4    Soares, R.5
  • 111
    • 55949118960 scopus 로고    scopus 로고
    • Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells
    • Park JH, Jin CY, Lee BK, Kim GY, Choi YH, et al.: Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells. Food and Chemical Toxicology 46, 3684-3690, 2008.
    • (2008) Food and Chemical Toxicology , vol.46 , pp. 3684-3690
    • Park, J.H.1    Jin, C.Y.2    Lee, B.K.3    Kim, G.Y.4    Choi, Y.H.5
  • 112
    • 59249108657 scopus 로고    scopus 로고
    • NGN-induced apoptosis is attenuated by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells
    • Jin CY, Park C, Lee JH, Chung KT, Kwon TK, et al.: NGN-induced apoptosis is attenuated by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells. Toxicology in Vitro 23, 259-265, 2009.
    • (2009) Toxicology in Vitro , vol.23 , pp. 259-265
    • Jin, C.Y.1    Park, C.2    Lee, J.H.3    Chung, K.T.4    Kwon, T.K.5
  • 113
    • 33747881688 scopus 로고    scopus 로고
    • Naringenin-induced apoptosis via activation of NF-kappaB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells
    • Kanno S, Tomizawa A, Ohtake T, Koiwai T, Ujibe M, et al.: Naringenin-induced apoptosis via activation of NF-kappaB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells. Toxicology Letter 166, 131-139, 2006.
    • (2006) Toxicology Letter , vol.166 , pp. 131-139
    • Kanno, S.1    Tomizawa, A.2    Ohtake, T.3    Koiwai, T.4    Ujibe, M.5
  • 114
    • 3042569646 scopus 로고    scopus 로고
    • Phytoestrogens /flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance
    • Imai Y, Tsukahara S, Asada S, and Sugimoto Y: Phytoestrogens /flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. Cancer Research 64, 4346-4352, 2004.
    • (2004) Cancer Research , vol.64 , pp. 4346-4352
    • Imai, Y.1    Tsukahara, S.2    Asada, S.3    Sugimoto, Y.4
  • 116
    • 2142711101 scopus 로고    scopus 로고
    • Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport
    • Zhang S, Yang X, and Morris ME: Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport. Molecular Pharmacology 65, 1208-1216, 2004.
    • (2004) Molecular Pharmacology , vol.65 , pp. 1208-1216
    • Zhang, S.1    Yang, X.2    Morris, M.E.3
  • 117
    • 84866469084 scopus 로고    scopus 로고
    • Natural products for cancer-Targeted therapy: Citrus flavonoids as potent chemoprevent agents
    • Meiyanto E, Hermawan A, and Anindyajati: Natural products for cancer-Targeted therapy: Citrus flavonoids as potent chemoprevent agents. Asian Pacific Journal of Cancer Prevention 13, 427-436, 2012.
    • (2012) Asian Pacific Journal of Cancer Prevention , vol.13 , pp. 427-436
    • Meiyanto, E.1    Hermawan, A.2    Anindyajati3
  • 118
    • 84907699846 scopus 로고    scopus 로고
    • A naringenin-Tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells
    • Hatkevich T, Ramos J, Santos-Sanchez I, and Patel YM: A naringenin-Tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells. Exp Cell Res 2014. http://dx.doi.org/10.1016/j. yexcr.2014.05.017
    • (2014) Exp Cell Res
    • Hatkevich, T.1    Ramos, J.2    Santos-Sanchez, I.3    Patel, Y.M.4
  • 119
    • 58149233844 scopus 로고    scopus 로고
    • Naringenin protects against cadmiuminduced oxidative renal dysfunction in rats
    • Renugadevi J and Prabu SM: Naringenin protects against cadmiuminduced oxidative renal dysfunction in rats. Toxicology 256, 128-134, 2009.
    • (2009) Toxicology , vol.256 , pp. 128-134
    • Renugadevi, J.1    Prabu, S.M.2
  • 120
  • 121
    • 35148882512 scopus 로고    scopus 로고
    • Inhibitory effect of Naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages
    • Hirai S, Kim YI, Goto T, Kang MS, Yoshimura M, et al.: Inhibitory effect of Naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Science 81, 1272-1279, 2007.
    • (2007) Life Science , vol.81 , pp. 1272-1279
    • Hirai, S.1    Kim, Y.I.2    Goto, T.3    Kang, M.S.4    Yoshimura, M.5
  • 122
    • 23844523855 scopus 로고    scopus 로고
    • Production of cytokine and NO by RAW 264.7 macrophages and PBMC in vitro incubation with flavonoids
    • Lyu SY and Park WB: Production of cytokine and NO by RAW 264.7 macrophages and PBMC in vitro incubation with flavonoids. Archives of Pharmacal Research 28, 573-581, 2005.
    • (2005) Archives of Pharmacal Research , vol.28 , pp. 573-581
    • Lyu, S.Y.1    Park, W.B.2
  • 123
    • 33646076968 scopus 로고    scopus 로고
    • Structure-Activity relations of inhibitory effects of various flavonoids on lipopolysaccharide-induced prostaglandin E2 production in rat peritoneal macrophages: Comparison between subclasses of flavonoids
    • Tanakoishikawa Y, Goto M, and Yamaki K: Structure-Activity relations of inhibitory effects of various flavonoids on lipopolysaccharide-induced prostaglandin E2 production in rat peritoneal macrophages: comparison between subclasses of flavonoids. Phytomedicine 13, 310-317, 2006.
    • (2006) Phytomedicine , vol.13 , pp. 310-317
    • Tanakoishikawa, Y.1    Goto, M.2    Yamaki, K.3
  • 124
    • 77955502406 scopus 로고    scopus 로고
    • Novel regulatory mechanism of Naringenin through inhibition of T lymphocyte function in contact hypersensitivity suppression
    • Fang F, Tang Y, Gao Z, and Xu Q: Novel regulatory mechanism of Naringenin through inhibition of T lymphocyte function in contact hypersensitivity suppression. Biochemical and Biophysical Research Communications 397, 163-169, 2010.
    • (2010) Biochemical and Biophysical Research Communications , vol.397 , pp. 163-169
    • Fang, F.1    Tang, Y.2    Gao, Z.3    Xu, Q.4
  • 126
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK: Inflammation, atherosclerosis, and coronary artery disease. New England Journal of Medicine 352, 1685-1695, 2005.
    • (2005) New England Journal of Medicine , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 127
    • 84864030693 scopus 로고    scopus 로고
    • Naringenin inhibits TNF-A induced VSMC proliferation and migration via induction of HO-1
    • Chen S, Ding Y, Tao W, Zhang W, Liang T, et al.: Naringenin inhibits TNF-A induced VSMC proliferation and migration via induction of HO-1. Food and Chemical Toxicology 50, 3025-3031, 2012.
    • (2012) Food and Chemical Toxicology , vol.50 , pp. 3025-3031
    • Chen, S.1    Ding, Y.2    Tao, W.3    Zhang, W.4    Liang, T.5
  • 128
    • 84856229747 scopus 로고    scopus 로고
    • 2S Naringenin from Typha angustata inhibits vascular smooth muscle cell proliferation via a G0/G1 Arrest
    • Lee JJ, Yi H, Kim IS, Kim Y, Nhiem NX, et al.: (2S)Naringenin from Typha angustata inhibits vascular smooth muscle cell proliferation via a G0/G1 Arrest. Journal of Ethnopharmacology 139, 873-878, 2012.
    • (2012) Journal of Ethnopharmacology , vol.139 , pp. 873-878
    • Lee, J.J.1    Yi, H.2    Kim, I.S.3    Kim, Y.4    Nhiem, N.X.5
  • 129
    • 84864762802 scopus 로고    scopus 로고
    • The phytoestrogen 8-prenyl Naringenin inhibits agonist-dependent activation of human platelets
    • Di VC, Bertoni A, Nalin M, Sampietro S, Zanfa M, et al.: The phytoestrogen 8-prenyl Naringenin inhibits agonist-dependent activation of human platelets. Biochimica et Biophysica Acta 1820, 1724-1733, 2012.
    • (2012) Biochimica et Biophysica Acta , vol.1820 , pp. 1724-1733
    • Di, V.C.1    Bertoni, A.2    Nalin, M.3    Sampietro, S.4    Zanfa, M.5
  • 130
    • 67650970098 scopus 로고    scopus 로고
    • Anti-inflammatory activity of Naringin and the biosynthesised Naringenin by Naringinase immobilized in microstructured materials in a model of DSS-induced colitis in mice
    • Amaro MI, Rocha J, Vila-Real H, Eduardo-Figueira M, Mota-Filipe H, et al.: Anti-inflammatory activity of Naringin and the biosynthesised Naringenin by Naringinase immobilized in microstructured materials in a model of DSS-induced colitis in mice. Food Research International 42, 1010-1017, 2009.
    • (2009) Food Research International , vol.42 , pp. 1010-1017
    • Amaro, M.I.1    Rocha, J.2    Vila-Real, H.3    Eduardo-Figueira, M.4    Mota-Filipe, H.5
  • 131
    • 80052044942 scopus 로고    scopus 로고
    • The flavonone Naringenin inhibits chloride secretion in isolated colonic epithelia
    • Collins D, Kopic S, Geibel JP, Hogan AM, Medani M, et al.: The flavonone Naringenin inhibits chloride secretion in isolated colonic epithelia. European Journal of Pharmacology 668(1-2), 271-277, 2011.
    • (2011) European Journal of Pharmacology , vol.668 , Issue.1-2 , pp. 271-277
    • Collins, D.1    Kopic, S.2    Geibel, J.P.3    Hogan, A.M.4    Medani, M.5
  • 132
    • 77956184900 scopus 로고    scopus 로고
    • Suppression of hepatic oxidative events and regulation of iNOS expression in the liver by Naringenin in fructose-Administered rats
    • Kannappan S, Palanisamy N, and Anuradha CV: Suppression of hepatic oxidative events and regulation of iNOS expression in the liver by Naringenin in fructose-Administered rats. European Journal of Pharmacology 645, 177-184, 2010.
    • (2010) European Journal of Pharmacology , vol.645 , pp. 177-184
    • Kannappan, S.1    Palanisamy, N.2    Anuradha, C.V.3
  • 135
    • 84870065076 scopus 로고    scopus 로고
    • Naringenin ameliorates Alzheimer's disease (AD)-Type neurodegeneration with cognitive impairment (AD-TNDCI) caused by the intracerebroventricular-streptozotocin in rat model
    • Khan BM, Khan MM, Khan A, Md. Ahmed E, Ishrat T, et al.: Naringenin ameliorates Alzheimer's disease (AD)-Type neurodegeneration with cognitive impairment (AD-TNDCI) caused by the intracerebroventricular-streptozotocin in rat model. Neurochemistry International 61, 1081-1093, 2012.
    • (2012) Neurochemistry International , vol.61 , pp. 1081-1093
    • Khan, B.M.1    Khan, M.M.2    Khan, A.3    Md. Ahmed, E.4    Ishrat, T.5
  • 137
    • 25444508963 scopus 로고    scopus 로고
    • Neuroprotective properties of the natural phenolic antioxidants curcumin and Naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease
    • Zbarsky V, Datla KP, Parkar S, Rai DK, Aruoma OI, et al.: Neuroprotective properties of the natural phenolic antioxidants curcumin and Naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease. Free Radical Research 39, 1119-1125, 2005.
    • (2005) Free Radical Research , vol.39 , pp. 1119-1125
    • Zbarsky, V.1    Datla, K.P.2    Parkar, S.3    Rai, D.K.4    Aruoma, O.I.5
  • 138
    • 77954388465 scopus 로고    scopus 로고
    • Protective effects of silybin and analogues against X-ray radiation-induced damage
    • Fu H, Lin M, Katsumura Y, Yokoya A, Hata K, et al.: Protective effects of silybin and analogues against X-ray radiation-induced damage. Acta Biochim Biophys Sin 42, 489-495, 2010.
    • (2010) Acta Biochim Biophys Sin , vol.42 , pp. 489-495
    • Fu, H.1    Lin, M.2    Katsumura, Y.3    Yokoya, A.4    Hata, K.5
  • 139
    • 20344377141 scopus 로고    scopus 로고
    • Modulation of radiation-induced alteration in the antioxidant status of mice by NG
    • Jagetia GC and Reddy TK: Modulation of radiation-induced alteration in the antioxidant status of mice by NG. Life Sciences 77, 780-794, 2005.
    • (2005) Life Sciences , vol.77 , pp. 780-794
    • Jagetia, G.C.1    Reddy, T.K.2
  • 140
    • 0037480882 scopus 로고    scopus 로고
    • Naringin, a citrus flavonone, protects against radiation-induced chromosome damage in mouse bone marrow
    • Jagetia GC, Venkatesha VA, and Reddy TK: Naringin, a citrus flavonone, protects against radiation-induced chromosome damage in mouse bone marrow. Mutagenesis 18, 337-343, 2003.
    • (2003) Mutagenesis , vol.18 , pp. 337-343
    • Jagetia, G.C.1    Venkatesha, V.A.2    Reddy, T.K.3
  • 141
    • 84876883246 scopus 로고    scopus 로고
    • The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice
    • Maximov PY, Lee TM, and Jordan VC: The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Current Clinical Pharmacology 8, 135-155, 2013.
    • (2013) Current Clinical Pharmacology , vol.8 , pp. 135-155
    • Maximov, P.Y.1    Lee, T.M.2    Jordan, V.C.3
  • 142
    • 0028805583 scopus 로고
    • Naringenin: A weakly estrogenic bioflavonoid that exhibits antiestrogenic activity
    • Ruh MF, Zacharewski T, Connor K, Howell J, Chen I, et al.: Naringenin: A weakly estrogenic bioflavonoid that exhibits antiestrogenic activity. Biochemical Pharmacology 5, 1485-1493, 1995.
    • (1995) Biochemical Pharmacology , vol.5 , pp. 1485-1493
    • Ruh, M.F.1    Zacharewski, T.2    Connor, K.3    Howell, J.4    Chen, I.5
  • 143
    • 84877837248 scopus 로고    scopus 로고
    • Hop extracts and hop substances in treatment of menopausal complaints
    • Keiler AM, Zierau O, and Kretzschmar G: Hop extracts and hop substances in treatment of menopausal complaints. Planta Medica 79, 576-579, 2013
    • (2013) Planta Medica , vol.79 , pp. 576-579
    • Keiler, A.M.1    Zierau, O.2    Kretzschmar, G.3
  • 145
    • 0031831117 scopus 로고    scopus 로고
    • Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF7 cell proliferation assay
    • Breinholt V and Larsen JC: Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF7 cell proliferation assay. Chemical in Research in Toxicology, 11, 622-629, 1998.
    • (1998) Chemical in Research in Toxicology , vol.11 , pp. 622-629
    • Breinholt, V.1    Larsen, J.C.2
  • 147
    • 81255185070 scopus 로고    scopus 로고
    • Double directional ad-justing estrogenic effect of naringin from Rhi-zoma drynariae (Gusuibu)
    • Guo D, Wang J, Wang X, Luo H, Zhang H et al.: Double directional ad-justing estrogenic effect of naringin from Rhi-zoma drynariae (Gusuibu). Journal of Ethnopharmacology 138, 451-457, 2011.
    • (2011) Journal of Ethnopharmacology , vol.138 , pp. 451-457
    • Guo, D.1    Wang, J.2    Wang, X.3    Luo, H.4    Zhang, H.5
  • 148
    • 84887686802 scopus 로고    scopus 로고
    • Naringenin: A partial agonist on estrogen receptor in T47D-KBluc breast cancer cells
    • Kim S and Park TI: Naringenin: a partial agonist on estrogen receptor in T47D-KBluc breast cancer cells. International Journal of Clinical and Experimental Medicine 6, 890-899, 2013.
    • (2013) International Journal of Clinical and Experimental Medicine , vol.6 , pp. 890-899
    • Kim, S.1    Park, T.I.2


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