Narirutin fraction from citrus peels attenuates LPS-stimulated inflammatory response through inhibition of NF-κB and MAPKs activation

Food and Chemical Toxicology

Volumn 50, Issue 10, 2012, Pages 3498-3504

  Ha, Sang Keun ^a   Park, Ho Young ^a   Eom, Hyojin ^a   Kim, Yoonsook ^a   Choi, Inwook ^a  

^a Korea Food Research Institute   (South Korea)

Author keywords

Citrus peel; Inflammation; Macrophage; Narirutin

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; JANUS KINASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NARIRUTIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL FRACTIONATION; CELL VIABILITY; CHRONIC INFLAMMATION; CITRUS FRUIT; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE RESPONSE; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CELL LINE; CELL SURVIVAL; CITRUS; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; DISACCHARIDES; FLAVANONES; FRUIT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR STRUCTURE; NF-KAPPA B; NITRIC OXIDE; PLANT EXTRACTS;

CITRUS;

EID: 84865447939     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.07.007     Document Type: Article

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