Poly (lactide-co-glycolide) acid nanoencapsulation of a synthetic coumarin: Cytotoxicity and bio-distribution in mice, in cancer cell line and interaction with calf thymus DNA as target

Toxicology and Applied Pharmacology

Volumn 253, Issue 3, 2011, Pages 270-281

  Bhattacharyya, Soumya Sundar ^a   Paul, Saili ^a   De, Arnab ^a   Das, Durba ^a   Samadder, Asmita ^a   Boujedaini, Naoual ^b   Khuda Bukhsh, Anisur Rahman ^a  

^a UNIVERSITY OF KALYANI   (India)

^b Boiron Laboratory   (France)

Author keywords

Atomic force microscopy; Blood brain barrier; Circular dichroism spectroscopy; DNA drug interaction; PLGA; Scanning electron microscopy

Indexed keywords

NANOPARTICLE; POLY (LACTIDE CO GLYCOLIDE) ACID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; BLOOD BRAIN BARRIER; BRAIN TISSUE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG DNA INTERACTION; DRUG UPTAKE; HUMAN; HUMAN CELL; KIDNEY PARENCHYMA; LIVER; MELANOMA CELL; MONONUCLEAR CELL; NANOENCAPSULATION; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SKIN CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CATTLE; CELL LINE, TUMOR; CELL SURVIVAL; CIRCULAR DICHROISM; COUMARINS; DNA; HUMANS; IN SITU NICK-END LABELING; LACTIC ACID; MICE; NANOCAPSULES; POLYGLYCOLIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION;

MUS;

EID: 79956315031     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.04.010     Document Type: Article

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