Naringenin-induced apoptosis is attenuated by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells

Toxicology in Vitro

Volumn 23, Issue 2, 2009, Pages 259-265

  Jin, Cheng Yun ^a   Park, Cheol ^b   Lee, Jun Hyuk ^b   Chung, Kyung Tae ^a   Kwon, Taeg Kyu ^c   Kim, Gi Young ^d   Choi, Byung Tae ^e   Choi, Yung Hyun ^a,b  

^a Dong Eui University   (South Korea)

^b Dong Eui University   (South Korea)

^c Keimyung University   (South Korea)

^d Jeju National University   (South Korea)

^e Pusan National University   (South Korea)

Author keywords

Apoptosis; Bcl 2; MMP; Naringenin; U937

Indexed keywords

2 AMINO 6 BROMO 4 (1 CYANO 2 ETHOXY 2 OXOETHYL) 4H CHROMENE 3 CARBOXYLIC ACID ETHYL ESTER; CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 9; CASPASE 9 INHIBITOR; CYTOCHROME C; NARINGENIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL 2 INHIBITOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRAIN U937; DOSE RESPONSE; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; ENZYME METABOLISM; LEUKEMIA; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZOPYRANS; CASPASES; CELL SURVIVAL; CYTOCHROMES C; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; ESTROGEN ANTAGONISTS; FLAVANONES; HUMANS; LEUKEMIA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NITRILES; PROTO-ONCOGENE PROTEINS C-BCL-2; U937 CELLS;

CITRUS;

EID: 59249108657     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2008.12.005     Document Type: Article

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