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Volumn 16, Issue 1, 2014, Pages 193-217

Oxidative stress and its significant roles in neurodegenerative diseases and cancer

Author keywords

Cancer; Carbonyl proteins; DNA damage; Lipid peroxidation; Neurodegenerative diseases; Oxidative stress; Oxysterol; Protein damage; Stem cells

Indexed keywords

8 NITROGUANINE; AMYLOID BETA PROTEIN; CD133 ANTIGEN; CYCLINE; DEOXYADENOSINE TRIPHOSPHATE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; HEAT SHOCK PROTEIN 70; HERMES ANTIGEN; JANUS KINASE; NITRIC OXIDE; OXIDOPAMINE; OXYSTEROL; PROTEIN P53; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84919789643     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms16010193     Document Type: Review
Times cited : (359)

References (144)
  • 1
    • 34250888056 scopus 로고    scopus 로고
    • Regulation of nox and duox enzymatic activity and expression
    • Lambeth, J.D.; Kawahara, T.; Diebold, B. Regulation of nox and duox enzymatic activity and expression. Free Radic. Biol. Med. 2007, 43, 319-331.
    • (2007) Free Radic. Biol. Med , vol.43 , pp. 319-331
    • Lambeth, J.D.1    Kawahara, T.2    Diebold, B.3
  • 2
    • 77956233017 scopus 로고    scopus 로고
    • The role of inos-mediated DNA damage in infection-and asbestos-induced carcinogenesis
    • Hiraku, Y.; Kawanishi, S.; Ichinose, T.; Murata, M. The role of inos-mediated DNA damage in infection-and asbestos-induced carcinogenesis. Ann. N. Y. Acad. Sci. 2010, 1203, 15-22.
    • (2010) Ann. N. Y. Acad. Sci , vol.1203 , pp. 15-22
    • Hiraku, Y.1    Kawanishi, S.2    Ichinose, T.3    Murata, M.4
  • 3
    • 84883890972 scopus 로고    scopus 로고
    • Oxidative stress and lipid peroxidation products in cancer progression and therapy
    • Barrera, G. Oxidative stress and lipid peroxidation products in cancer progression and therapy. ISRN Oncol. 2012, doi:org/10.5402/2012/137289.
    • (2012) ISRN Oncol
    • Barrera, G.1
  • 4
    • 80052261937 scopus 로고    scopus 로고
    • Lipid peroxidation and neurodegenerative disease
    • Reed, T.T. Lipid peroxidation and neurodegenerative disease. Free Radic. Biol. Med. 2011, 51, 1302-1319.
    • (2011) Free Radic. Biol. Med , vol.51 , pp. 1302-1319
    • Reed, T.T.1
  • 5
    • 23944478990 scopus 로고    scopus 로고
    • A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress
    • Del Rio, D.; Stewart, A.J.; Pellegrini, N. A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress. Nutr. Metab. Cardiovasc. Dis. 2005, 15, 316-328.
    • (2005) Nutr. Metab. Cardiovasc. Dis , vol.15 , pp. 316-328
    • Del Rio, D.1    Stewart, A.J.2    Pellegrini, N.3
  • 7
    • 80051472136 scopus 로고    scopus 로고
    • Oxysterols as biomarkers in neurodegenerative diseases
    • Leoni, V.; Caccia, C. Oxysterols as biomarkers in neurodegenerative diseases. Chem. Phys. Lipids 2011, 164, 515-524.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 515-524
    • Leoni, V.1    Caccia, C.2
  • 8
    • 33846811272 scopus 로고    scopus 로고
    • Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: Reduction during atorvastatin and fenofibrate therapy
    • Arca, M.; Natoli, S.; Micheletta, F.; Riggi, S.; di Angelantonio, E.; Montali, A.; Antonini, T.M.; Antonini, R.; Diczfalusy, U.; Iuliano, L. Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: Reduction during atorvastatin and fenofibrate therapy. Free Radic. Biol. Med. 2007, 42, 698-705.
    • (2007) Free Radic. Biol. Med , vol.42 , pp. 698-705
    • Arca, M.1    Natoli, S.2    Micheletta, F.3    Riggi, S.4    Di Angelantonio, E.5    Montali, A.6    Antonini, T.M.7    Antonini, R.8    Diczfalusy, U.9    Iuliano, L.10
  • 10
    • 0031729620 scopus 로고    scopus 로고
    • Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production
    • Lizard, G.; Gueldry, S.; Sordet, O.; Monier, S.; Athias, A.; Miguet, C.; Bessede, G.; Lemaire, S.; Solary, E.; Gambert, P. Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production. FASEB J. 1998, 12, 1651-1663.
    • (1998) FASEB J , vol.12 , pp. 1651-1663
    • Lizard, G.1    Gueldry, S.2    Sordet, O.3    Monier, S.4    Athias, A.5    Miguet, C.6    Bessede, G.7    Lemaire, S.8    Solary, E.9    Gambert, P.10
  • 13
    • 0032586846 scopus 로고    scopus 로고
    • Peroxynitrite induces tryosine nitration and modulates tyrosine phosphorylation of synaptic proteins
    • Di Stasi, A.M.; Mallozzi, C.; Macchia, G.; Petrucci, T.C.; Minetti, M. Peroxynitrite induces tryosine nitration and modulates tyrosine phosphorylation of synaptic proteins. J. Neurochem. 1999, 73, 727-735.
    • (1999) J. Neurochem , vol.73 , pp. 727-735
    • Di Stasi, A.M.1    Mallozzi, C.2    Macchia, G.3    Petrucci, T.C.4    Minetti, M.5
  • 14
    • 0032853993 scopus 로고    scopus 로고
    • Protein carbonyl formation and tyrosine nitration as markers of oxidative damage during ischaemia-reperfusion injury to rat sciatic nerve
    • He, K.; Nukada, H.; McMorran, P.D.; Murphy, M.P. Protein carbonyl formation and tyrosine nitration as markers of oxidative damage during ischaemia-reperfusion injury to rat sciatic nerve. Neuroscience 1999, 94, 909-916.
    • (1999) Neuroscience , vol.94 , pp. 909-916
    • He, K.1    Nukada, H.2    McMorran, P.D.3    Murphy, M.P.4
  • 15
    • 2142695253 scopus 로고    scopus 로고
    • Oxidative protein damage parameters in plasma in chronic experimental diabetes in rats
    • Kayali, R.; Telci, A.; Cakatay, U.; Karaca, C.; Akcay, T.; Sivas, A.; Altug, T. Oxidative protein damage parameters in plasma in chronic experimental diabetes in rats. Eur. J. Med. Res. 2003, 8, 307-312.
    • (2003) Eur. J. Med. Res , vol.8 , pp. 307-312
    • Kayali, R.1    Telci, A.2    Cakatay, U.3    Karaca, C.4    Akcay, T.5    Sivas, A.6    Altug, T.7
  • 16
    • 0032880537 scopus 로고    scopus 로고
    • Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: Evidence for neutrophil-mediated hydroxylation, nitration, and chlorination. Crit
    • Lamb, N.J.; Gutteridge, J.M.; Baker, C.; Evans, T.W.; Quinlan, G.J. Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: Evidence for neutrophil-mediated hydroxylation, nitration, and chlorination. Crit. Care Med. 1999, 27, 1738-1744.
    • (1999) Care Med , vol.27 , pp. 1738-1744
    • Lamb, N.J.1    Gutteridge, J.M.2    Baker, C.3    Evans, T.W.4    Quinlan, G.J.5
  • 17
    • 0031702686 scopus 로고    scopus 로고
    • Increased nitrotyrosine in the diabetic placenta: Evidence for oxidative stress
    • Lyall, F.; Gibson, J.L.; Greer, I.A.; Brockman, D.E.; Eis, A.L.; Myatt, L. Increased nitrotyrosine in the diabetic placenta: Evidence for oxidative stress. Diabetes Care 1998, 21, 1753-1758.
    • (1998) Diabetes Care , vol.21 , pp. 1753-1758
    • Lyall, F.1    Gibson, J.L.2    Greer, I.A.3    Brockman, D.E.4    Eis, A.L.5    Myatt, L.6
  • 20
    • 84881240163 scopus 로고    scopus 로고
    • Advanced glycoxidation and lipoxidation end products (ages and ales): An overview of their mechanisms of formation
    • Vistoli, G.; de Maddis, D.; Cipak, A.; Zarkovic, N.; Carini, M.; Aldini, G. Advanced glycoxidation and lipoxidation end products (ages and ales): An overview of their mechanisms of formation. Free Radic. Res. 2013, 47 (Suppl. 1), 3-27.
    • (2013) Free Radic. Res , vol.47 , pp. 3-27
    • Vistoli, G.1    De Maddis, D.2    Cipak, A.3    Zarkovic, N.4    Carini, M.5    Aldini, G.6
  • 21
    • 17844403545 scopus 로고    scopus 로고
    • Role of oxidative carbonylation in protein quality control and senescence
    • Nystrom, T. Role of oxidative carbonylation in protein quality control and senescence. EMBO J. 2005, 24, 1311-1317.
    • (2005) EMBO J , vol.24 , pp. 1311-1317
    • Nystrom, T.1
  • 24
    • 0029965252 scopus 로고    scopus 로고
    • Analysis of protein carbonyls with 2,4-dinitrophenyl hydrazine and its antibodies by immunoblot in two-dimensional gel electrophoresis
    • Nakamura, A.; Goto, S. Analysis of protein carbonyls with 2,4-dinitrophenyl hydrazine and its antibodies by immunoblot in two-dimensional gel electrophoresis. J. Biochem. 1996, 119, 768-774.
    • (1996) J. Biochem , vol.119 , pp. 768-774
    • Nakamura, A.1    Goto, S.2
  • 28
    • 55249111076 scopus 로고    scopus 로고
    • Tandem ms precursor-ion scan approach to identify variable covalent modification of albumin cys34: A new tool for studying vascular carbonylation
    • Aldini, G.; Regazzoni, L.; Orioli, M.; Rimoldi, I.; Facino, R.M.; Carini, M. A tandem ms precursor-ion scan approach to identify variable covalent modification of albumin cys34: A new tool for studying vascular carbonylation. J. Mass Spectrom. 2008, 43, 1470-1481.
    • (2008) J. Mass Spectrom , vol.43 , pp. 1470-1481
    • Aldini, G.1    Regazzoni, L.2    Orioli, M.3    Rimoldi, I.4    Facino, R.M.5    Carini, M.A.6
  • 29
    • 80054873045 scopus 로고    scopus 로고
    • To tag or not to tag: A comparative evaluation of immunoaffinity-labeling and tandem mass spectrometry for the identification and localization of posttranslational protein carbonylation by 4-hydroxy-2-nonenal, an end-product of lipid peroxidation
    • Guo, J.; Prokai, L. To tag or not to tag: A comparative evaluation of immunoaffinity-labeling and tandem mass spectrometry for the identification and localization of posttranslational protein carbonylation by 4-hydroxy-2-nonenal, an end-product of lipid peroxidation. J. Proteomics 2011, 74, 2360-2369.
    • (2011) J. Proteomics , vol.74 , pp. 2360-2369
    • Guo, J.1    Prokai, L.2
  • 30
    • 34247464726 scopus 로고    scopus 로고
    • Identification of carbonylated proteins from enriched rat skeletal muscle mitochondria using affinity chromatography-stable isotope labeling and tandem mass spectrometry
    • Meany, D.L.; Xie, H.; Thompson, L.V.; Arriaga, E.A.; Griffin, T.J. Identification of carbonylated proteins from enriched rat skeletal muscle mitochondria using affinity chromatography-stable isotope labeling and tandem mass spectrometry. Proteomics 2007, 7, 1150-1163.
    • (2007) Proteomics , vol.7 , pp. 1150-1163
    • Meany, D.L.1    Xie, H.2    Thompson, L.V.3    Arriaga, E.A.4    Griffin, T.J.5
  • 31
    • 17644362744 scopus 로고    scopus 로고
    • Affinity chromatographic selection of carbonylated proteins followed by identification of oxidation sites using tandem mass spectrometry
    • Mirzaei, H.; Regnier, F. Affinity chromatographic selection of carbonylated proteins followed by identification of oxidation sites using tandem mass spectrometry. Anal. Chem. 2005, 77, 2386-2392.
    • (2005) Anal. Chem , vol.77 , pp. 2386-2392
    • Mirzaei, H.1    Regnier, F.2
  • 32
    • 77950623821 scopus 로고    scopus 로고
    • Identification of carbonylation sites in apomyoglobin after exposure to 4-hydroxy-2-nonenal by solid-phase enrichment and liquid chromatography-electrospray ionization tandem mass spectrometry
    • Rauniyar, N.; Prokai-Tatrai, K.; Prokai, L. Identification of carbonylation sites in apomyoglobin after exposure to 4-hydroxy-2-nonenal by solid-phase enrichment and liquid chromatography-electrospray ionization tandem mass spectrometry. J. Mass Spectrom. 2010, 45, 398-410.
    • (2010) J. Mass Spectrom , vol.45 , pp. 398-410
    • Rauniyar, N.1    Prokai-Tatrai, K.2    Prokai, L.3
  • 33
    • 79956191022 scopus 로고    scopus 로고
    • Role of oxidative stress and DNA damage in human carcinogenesis
    • Kryston, T.B.; Georgiev, A.B.; Pissis, P.; Georgakilas, A.G. Role of oxidative stress and DNA damage in human carcinogenesis. Mutat. Res. 2011, 711, 193-201.
    • (2011) Mutat. Res , vol.711 , pp. 193-201
    • Kryston, T.B.1    Georgiev, A.B.2    Pissis, P.3    Georgakilas, A.G.4
  • 34
    • 84867474700 scopus 로고    scopus 로고
    • Oxidatively generated complex DNA damage: Tandem and clustered lesions
    • Cadet, J.; Ravanat, J.L.; TavernaPorro, M.; Menoni, H.; Angelov, D. Oxidatively generated complex DNA damage: Tandem and clustered lesions. Cancer Lett. 2012, 327, 5-15.
    • (2012) Cancer Lett , vol.327 , pp. 5-15
    • Cadet, J.1    Ravanat, J.L.2    Tavernaporro, M.3    Menoni, H.4    Angelov, D.5
  • 35
    • 84904717958 scopus 로고    scopus 로고
    • Oxidatively generated base damage to cellular DNA by hydroxyl radical and one-electron oxidants: Similarities and differences
    • Cadet, J.; Wagner, J.R. Oxidatively generated base damage to cellular DNA by hydroxyl radical and one-electron oxidants: Similarities and differences. Arch. Biochem. Biophys. 2014, 557, 47-54.
    • (2014) Arch. Biochem. Biophys , vol.557 , pp. 47-54
    • Cadet, J.1    Wagner, J.R.2
  • 36
    • 84886233092 scopus 로고    scopus 로고
    • Chromatin modifications associated with DNA double-strand breaks repair as potential targets for neurological diseases
    • Brochier, C.; Langley, B. Chromatin modifications associated with DNA double-strand breaks repair as potential targets for neurological diseases. Neurotherapeutics 2013, 10, 817-830.
    • (2013) Neurotherapeutics , vol.10 , pp. 817-830
    • Brochier, C.1    Langley, B.2
  • 37
    • 0035109348 scopus 로고    scopus 로고
    • Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging
    • Kawanishi, S.; Hiraku, Y.; Oikawa, S. Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging. Mutat. Res. 2001, 488, 65-76.
    • (2001) Mutat. Res , vol.488 , pp. 65-76
    • Kawanishi, S.1    Hiraku, Y.2    Oikawa, S.3
  • 38
    • 0042062310 scopus 로고    scopus 로고
    • Chemical basis of inflammation-induced carcinogenesis
    • Ohshima, H.; Tatemichi, M.; Sawa, T. Chemical basis of inflammation-induced carcinogenesis. Arch. Biochem. Biophys. 2003, 417, 3-11.
    • (2003) Arch. Biochem. Biophys , vol.417 , pp. 3-11
    • Ohshima, H.1    Tatemichi, M.2    Sawa, T.3
  • 39
    • 33745838635 scopus 로고    scopus 로고
    • Urinary measurement of 8-oxodg, 8-oxogua, and 5HMUra: A noninvasive assessment of oxidative damage to DNA
    • Olinski, R.; Rozalski, R.; Gackowski, D.; Foksinski, M.; Siomek, A.; Cooke, M.S. Urinary measurement of 8-oxodg, 8-oxogua, and 5HMUra: A noninvasive assessment of oxidative damage to DNA. Antioxid. Redox Signal. 2006, 8, 1011-1019.
    • (2006) Antioxid. Redox Signal , vol.8 , pp. 1011-1019
    • Olinski, R.1    Rozalski, R.2    Gackowski, D.3    Foksinski, M.4    Siomek, A.5    Cooke, M.S.6
  • 40
    • 38849090565 scopus 로고    scopus 로고
    • Measurement and meaning of oxidatively modified DNA lesions in urine
    • Cooke, M.S.; Olinski, R.; Loft, S. Measurement and meaning of oxidatively modified DNA lesions in urine. Cancer Epidemiol. Biomark. Prev. 2008, 17, 3-14.
    • (2008) Cancer Epidemiol. Biomark. Prev , vol.17 , pp. 3-14
    • Cooke, M.S.1    Olinski, R.2    Loft, S.3
  • 42
    • 0033565994 scopus 로고    scopus 로고
    • Oxygen and nitrogen are pro-carcinogens: Damage to DNA by reactive oxygen, chlorine and nitrogen species: Measurement, mechanism and the effects of nutrition
    • Halliwell, B. Oxygen and nitrogen are pro-carcinogens: Damage to DNA by reactive oxygen, chlorine and nitrogen species: Measurement, mechanism and the effects of nutrition. Mutat. Res. 1999, 443, 37-52.
    • (1999) Mutat. Res , vol.443 , pp. 37-52
    • Halliwell, B.1
  • 43
  • 44
    • 0037138481 scopus 로고    scopus 로고
    • Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species
    • Masuda, M.; Nishino, H.; Ohshima, H. Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species. Chem. Biol. Interact. 2002, 139, 187-197.
    • (2002) Chem. Biol. Interact , vol.139 , pp. 187-197
    • Masuda, M.1    Nishino, H.2    Ohshima, H.3
  • 46
    • 31644447230 scopus 로고    scopus 로고
    • Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chromatography-electrochemical detection coupled with immunoaffinity purification
    • Sawa, T.; Tatemichi, M.; Akaike, T.; Barbin, A.; Ohshima, H. Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chromatography-electrochemical detection coupled with immunoaffinity purification: Association with cigarette smoking. Free Radic. Biol. Med. 2006, 40, 711-720.
    • (2006) Association with Cigarette Smoking. Free Radic. Biol. Med , vol.40 , pp. 711-720
    • Sawa, T.1    Tatemichi, M.2    Akaike, T.3    Barbin, A.4    Ohshima, H.5
  • 47
    • 0030220956 scopus 로고    scopus 로고
    • Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily
    • Nash, H.M.; Bruner, S.D.; Scharer, O.D.; Kawate, T.; Addona, T.A.; Spooner, E.; Lane, W.S.; Verdine, G.L. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Curr. Biol. 1996, 6, 968-980.
    • (1996) Curr. Biol , vol.6 , pp. 968-980
    • Nash, H.M.1    Bruner, S.D.2    Scharer, O.D.3    Kawate, T.4    Addona, T.A.5    Spooner, E.6    Lane, W.S.7    Verdine, G.L.8
  • 48
    • 0032416476 scopus 로고    scopus 로고
    • The role of mismatch repair in the prevention of base pair mutations in saccharomyces cerevisiae
    • Earley, M.C.; Crouse, G.F. The role of mismatch repair in the prevention of base pair mutations in saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 1998, 95, 15487-15491.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15487-15491
    • Earley, M.C.1    Crouse, G.F.2
  • 49
    • 0033197818 scopus 로고    scopus 로고
    • MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-Guanine in S. Cerevisiae
    • Ni, T.T.; Marsischky, G.T.; Kolodner, R.D. MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-Guanine in S. cerevisiae. Mol. Cell 1999, 4, 439-444.
    • (1999) Mol. Cell , vol.4 , pp. 439-444
    • Ni, T.T.1    Marsischky, G.T.2    Kolodner, R.D.3
  • 50
    • 0030745912 scopus 로고    scopus 로고
    • In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in xeroderma pigmentosum patients
    • Reardon, J.T.; Bessho, T.; Kung, H.C.; Bolton, P.H.; Sancar, A. In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in xeroderma pigmentosum patients. Proc. Natl. Acad. Sci. USA 1997, 94, 9463-9468.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9463-9468
    • Reardon, J.T.1    Bessho, T.2    Kung, H.C.3    Bolton, P.H.4    Sancar, A.5
  • 53
    • 84878537085 scopus 로고    scopus 로고
    • Oxidative DNA damage and nucleotide excision repair
    • Melis, J.P.; van Steeg, H.; Luijten, M. Oxidative DNA damage and nucleotide excision repair. Antioxid. Redox Signal. 2013, 18, 2409-2419.
    • (2013) Antioxid. Redox Signal , vol.18 , pp. 2409-2419
    • Melis, J.P.1    Van Steeg, H.2    Luijten, M.3
  • 54
    • 0034708226 scopus 로고    scopus 로고
    • Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
    • Bruner, S.D.; Norman, D.P.; Verdine, G.L. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature 2000, 403, 859-866.
    • (2000) Nature , vol.403 , pp. 859-866
    • Bruner, S.D.1    Norman, D.P.2    Verdine, G.L.3
  • 55
    • 0028785105 scopus 로고
    • Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination
    • Yermilov, V.; Rubio, J.; Ohshima, H. Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination. FEBS Lett. 1995, 376, 207-210.
    • (1995) FEBS Lett , vol.376 , pp. 207-210
    • Yermilov, V.1    Rubio, J.2    Ohshima, H.3
  • 56
    • 0023015325 scopus 로고
    • Mutagenesis by apurinic/apyrimidinic sites
    • Loeb, L.A.; Preston, B.D. Mutagenesis by apurinic/apyrimidinic sites. Annu. Rev. Genet. 1986, 20, 201-230.
    • (1986) Annu. Rev. Genet , vol.20 , pp. 201-230
    • Loeb, L.A.1    Preston, B.D.2
  • 61
    • 0027212026 scopus 로고
    • Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia
    • Urosevic, N.; Krtolica, K.; Skaro-Milic, A.; Knezevic-Usaj, S.; Dujic, A. Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia. Int. J. Cancer 1993, 54, 249-254.
    • (1993) Int. J. Cancer , vol.54 , pp. 249-254
    • Urosevic, N.1    Krtolica, K.2    Skaro-Milic, A.3    Knezevic-Usaj, S.4    Dujic, A.5
  • 62
    • 0034745389 scopus 로고    scopus 로고
    • Patterns of p53 G→T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke
    • Hainaut, P.; Pfeifer, G.P. Patterns of p53 G→T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke. Carcinogenesis 2001, 22, 367-374.
    • (2001) Carcinogenesis , vol.22 , pp. 367-374
    • Hainaut, P.1    Pfeifer, G.P.2
  • 63
    • 0020726827 scopus 로고
    • Concentration of oxygen in lipid bilayers using a spin-label method
    • Subczynski, W.K.; Hyde, J.S. Concentration of oxygen in lipid bilayers using a spin-label method. Biophys. J. 1983, 41, 283-286.
    • (1983) Biophys. J , vol.41 , pp. 283-286
    • Subczynski, W.K.1    Hyde, J.S.2
  • 65
    • 0033594903 scopus 로고    scopus 로고
    • Cdna cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
    • Lund, E.G.; Guileyardo, J.M.; Russell, D.W. Cdna cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain. Proc. Natl. Acad. Sci. USA 1999, 96, 7238-7243.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7238-7243
    • Lund, E.G.1    Guileyardo, J.M.2    Russell, D.W.3
  • 66
    • 84899490048 scopus 로고    scopus 로고
    • Cholesterol as a causative factor in Alzheimer’s disease: A debatable hypothesis
    • Wood, W.G.; Li, L.; Muller, W.E.; Eckert, G.P. Cholesterol as a causative factor in Alzheimer’s disease: A debatable hypothesis. J. Neurochem. 2014, 129, 559-572.
    • (2014) J. Neurochem , vol.129 , pp. 559-572
    • Wood, W.G.1    Li, L.2    Muller, W.E.3    Eckert, G.P.4
  • 69
    • 84974727253 scopus 로고    scopus 로고
    • Protein oxidation in aging: Does it play a role in aging progression?
    • Reeg, S.; Grune, T. Protein oxidation in aging: Does it play a role in aging progression? Antioxid. Redox Signal. 2014, doi:10.1089/ars.2014.6062.
    • (2014) Antioxid. Redox Signal
    • Reeg, S.1    Grune, T.2
  • 72
    • 75949083202 scopus 로고    scopus 로고
    • Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates
    • Martinez, A.; Portero-Otin, M.; Pamplona, R.; Ferrer, I. Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates. Brain Pathol. 2010, 20, 281-297.
    • (2010) Brain Pathol , vol.20 , pp. 281-297
    • Martinez, A.1    Portero-Otin, M.2    Pamplona, R.3    Ferrer, I.4
  • 74
    • 70450222302 scopus 로고    scopus 로고
    • The role of lysosomal rupture in neuronal death
    • Yamashima, T.; Oikawa, S. The role of lysosomal rupture in neuronal death. Progress Neurobiol. 2009, 89, 343-358.
    • (2009) Progress Neurobiol , vol.89 , pp. 343-358
    • Yamashima, T.1    Oikawa, S.2
  • 75
    • 44949091276 scopus 로고    scopus 로고
    • Accumulation of nuclear DNA damage or neuron loss: Molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases
    • Brasnjevic, I.; Hof, P.R.; Steinbusch, H.W.; Schmitz, C. Accumulation of nuclear DNA damage or neuron loss: Molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases. DNA Repair 2008, 7, 1087-1097.
    • (2008) DNA Repair , vol.7 , pp. 1087-1097
    • Brasnjevic, I.1    Hof, P.R.2    Steinbusch, H.W.3    Schmitz, C.4
  • 76
    • 84904324446 scopus 로고    scopus 로고
    • DNA damage and its links to neurodegeneration
    • Madabhushi, R.; Pan, L.; Tsai, L.H. DNA damage and its links to neurodegeneration. Neuron 2014, 83, 266-282.
    • (2014) Neuron , vol.83 , pp. 266-282
    • Madabhushi, R.1    Pan, L.2    Tsai, L.H.3
  • 77
    • 84919786949 scopus 로고    scopus 로고
    • New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases
    • Mitra, J.; Guerrero, E.N.; Hegde, P.M.; Wang, H.; Boldogh, I.; Rao, K.S.; Mitra, S.; Hegde, M.L. New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases. Biomolecules 2014, 4, 678-703.
    • (2014) Biomolecules , vol.4 , pp. 678-703
    • Mitra, J.1    Guerrero, E.N.2    Hegde, P.M.3    Wang, H.4    Boldogh, I.5    Rao, K.S.6    Mitra, S.7    Hegde, M.L.8
  • 78
    • 59249102083 scopus 로고    scopus 로고
    • The wanderings of a free radical
    • Halliwell, B. The wanderings of a free radical. Free Radic. Biol. Med. 2009, 46, 531-542.
    • (2009) Free Radic. Biol. Med , vol.46 , pp. 531-542
    • Halliwell, B.1
  • 79
  • 80
    • 48449092397 scopus 로고    scopus 로고
    • Mechanism of metal-mediated DNA damage and apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells
    • Kobayashi, H.; Oikawa, S.; Umemura, S.; Hirosawa, I.; Kawanishi, S. Mechanism of metal-mediated DNA damage and apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells. Free Radic. Res. 2008, 42, 651-660.
    • (2008) Free Radic. Res , vol.42 , pp. 651-660
    • Kobayashi, H.1    Oikawa, S.2    Umemura, S.3    Hirosawa, I.4    Kawanishi, S.5
  • 82
    • 0035880007 scopus 로고    scopus 로고
    • Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins
    • Butterfield, D.A.; Kanski, J. Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins. Mech. Ageing Dev. 2001, 122, 945-962.
    • (2001) Mech. Ageing Dev , vol.122 , pp. 945-962
    • Butterfield, D.A.1    Kanski, J.2
  • 83
    • 84455173005 scopus 로고    scopus 로고
    • In vitro and in vivo aggregation of a fragment of huntingtin protein directly causes free radical production
    • Hands, S.; Sajjad, M.U.; Newton, M.J.; Wyttenbach, A. In vitro and in vivo aggregation of a fragment of huntingtin protein directly causes free radical production. J. Biol. Chem. 2011, 286, 44512-44520.
    • (2011) J. Biol. Chem , vol.286 , pp. 44512-44520
    • Hands, S.1    Sajjad, M.U.2    Newton, M.J.3    Wyttenbach, A.4
  • 84
    • 74549158769 scopus 로고    scopus 로고
    • Lipid peroxidation and etheno DNA adducts in white blood cells of liver fluke-infected patients: Protection by plasma α-tocopherol and praziquantel
    • Dechakhamphu, S.; Pinlaor, S.; Sitthithaworn, P.; Nair, J.; Bartsch, H.; Yongvanit, P. Lipid peroxidation and etheno DNA adducts in white blood cells of liver fluke-infected patients: Protection by plasma α-tocopherol and praziquantel. Cancer Epidemiol. Biomark. Prev. 2010, 19, 310-318.
    • (2010) Cancer Epidemiol. Biomark. Prev , vol.19 , pp. 310-318
    • Dechakhamphu, S.1    Pinlaor, S.2    Sitthithaworn, P.3    Nair, J.4    Bartsch, H.5    Yongvanit, P.6
  • 86
    • 77956174933 scopus 로고    scopus 로고
    • Accumulation of miscoding etheno-DNA adducts and highly expressed DNA repair during liver fluke-induced cholangiocarcinogenesis in hamsters
    • Dechakhamphu, S.; Pinlaor, S.; Sitthithaworn, P.; Bartsch, H.; Yongvanit, P. Accumulation of miscoding etheno-DNA adducts and highly expressed DNA repair during liver fluke-induced cholangiocarcinogenesis in hamsters. Mutat. Res. 2010, 691, 9-16.
    • (2010) Mutat. Res , vol.691 , pp. 9-16
    • Dechakhamphu, S.1    Pinlaor, S.2    Sitthithaworn, P.3    Bartsch, H.4    Yongvanit, P.5
  • 87
    • 82655172486 scopus 로고    scopus 로고
    • Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: A potential molecular marker for tumor metastasis
    • Loilome, W.; Wechagama, P.; Namwat, N.; Jusakul, A.; Sripa, B.; Miwa, M.; Kuver, R.; Yongvanit, P. Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: A potential molecular marker for tumor metastasis. Parasitol. Int. 2012, 61, 136-139.
    • (2012) Parasitol. Int , vol.61 , pp. 136-139
    • Loilome, W.1    Wechagama, P.2    Namwat, N.3    Jusakul, A.4    Sripa, B.5    Miwa, M.6    Kuver, R.7    Yongvanit, P.8
  • 89
    • 84883184233 scopus 로고    scopus 로고
    • Anti-apoptotic phenotypes of cholestan-3β,5α,6β-triol-resistant human cholangiocytes: Characteristics contributing to the genesis of cholangiocarcinoma
    • Jusakul, A.; Loilome, W.; Namwat, N.; Techasen, A.; Kuver, R.; Ioannou, G.N.; Savard, C.; Haigh, W.G.; Yongvanit, P. Anti-apoptotic phenotypes of cholestan-3β,5α,6β-triol-resistant human cholangiocytes: Characteristics contributing to the genesis of cholangiocarcinoma. J. Steroid Biochem. Mol. Biol. 2013, 138, 368-375.
    • (2013) J. Steroid Biochem. Mol. Biol , vol.138 , pp. 368-375
    • Jusakul, A.1    Loilome, W.2    Namwat, N.3    Techasen, A.4    Kuver, R.5    Ioannou, G.N.6    Savard, C.7    Haigh, W.G.8    Yongvanit, P.9
  • 90
    • 59649100968 scopus 로고    scopus 로고
    • Hsp70/nitric oxide relationship in apoptotic modulation during obstructive nephropathy
    • Manucha, W.; Valles, P. Hsp70/nitric oxide relationship in apoptotic modulation during obstructive nephropathy. Cell Stress Chaperones 2008, 13, 413-420.
    • (2008) Cell Stress Chaperones , vol.13 , pp. 413-420
    • Manucha, W.1    Valles, P.2
  • 91
    • 0036882395 scopus 로고    scopus 로고
    • Serpin structure, mechanism, and function
    • Gettins, P.G. Serpin structure, mechanism, and function. Chem. Rev. 2002, 102, 4751-4804.
    • (2002) Chem. Rev , vol.102 , pp. 4751-4804
    • Gettins, P.G.1
  • 92
    • 34249727056 scopus 로고    scopus 로고
    • Roles of serine proteases and matrix metalloproteinases in tumor invasion and angiogenesis
    • Masson, V. Roles of serine proteases and matrix metalloproteinases in tumor invasion and angiogenesis. Bull. Mem. Acad. R. Med. Belg. 2006, 161, 320-326.
    • (2006) Bull. Mem. Acad. R. Med. Belg , vol.161 , pp. 320-326
    • Masson, V.1
  • 94
    • 70149093209 scopus 로고    scopus 로고
    • Protein oxidation in breast microenvironment: Nipple aspirate fluid collected from breast cancer women contains increased protein carbonyl concentration
    • Mannello, F.; Tonti, G.A.; Medda, V. Protein oxidation in breast microenvironment: Nipple aspirate fluid collected from breast cancer women contains increased protein carbonyl concentration. Cell. Oncol. 2009, 31, 383-392.
    • (2009) Cell. Oncol , vol.31 , pp. 383-392
    • Mannello, F.1    Tonti, G.A.2    Medda, V.3
  • 96
    • 66149152688 scopus 로고    scopus 로고
    • Plasma protein carbonyls and breast cancer risk in sisters discordant for breast cancer from the new york site of the breast cancer family registry
    • Zipprich, J.; Terry, M.B.; Liao, Y.; Agrawal, M.; Gurvich, I.; Senie, R.; Santella, R.M. Plasma protein carbonyls and breast cancer risk in sisters discordant for breast cancer from the new york site of the breast cancer family registry. Cancer Res. 2009, 69, 2966-2972.
    • (2009) Cancer Res , vol.69 , pp. 2966-2972
    • Zipprich, J.1    Terry, M.B.2    Liao, Y.3    Agrawal, M.4    Gurvich, I.5    Senie, R.6    Santella, R.M.7
  • 97
    • 84858116393 scopus 로고    scopus 로고
    • Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis
    • Murata, M.; Thanan, R.; Ma, N.; Kawanishi, S. Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis. J. Biomed. Biotechnol. 2012, doi:10.1155/2012/623019.
    • (2012) J. Biomed. Biotechnol
    • Murata, M.1    Thanan, R.2    Ma, N.3    Kawanishi, S.4
  • 99
    • 82655162242 scopus 로고    scopus 로고
    • Oxidative and nitrative DNA damage: Key events in opisthorchiasis-induced carcinogenesis
    • Yongvanit, P.; Pinlaor, S.; Bartsch, H. Oxidative and nitrative DNA damage: Key events in opisthorchiasis-induced carcinogenesis. Parasitol. Int. 2012, 61, 130-135.
    • (2012) Parasitol. Int , vol.61 , pp. 130-135
    • Yongvanit, P.1    Pinlaor, S.2    Bartsch, H.3
  • 101
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek, R.M., Jr.; Blaser, M.J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat. Rev. Cancer 2002, 2, 28-37.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 28-37
    • Peek, R.M.1    Blaser, M.J.2
  • 102
    • 34249894787 scopus 로고    scopus 로고
    • Nitrative and oxidative DNA damage in cervical intraepithelial neoplasia associated with human papilloma virus infection
    • Hiraku, Y.; Tabata, T.; Ma, N.; Murata, M.; Ding, X.; Kawanishi, S. Nitrative and oxidative DNA damage in cervical intraepithelial neoplasia associated with human papilloma virus infection. Cancer Sci. 2007, 98, 964-972.
    • (2007) Cancer Sci , vol.98 , pp. 964-972
    • Hiraku, Y.1    Tabata, T.2    Ma, N.3    Murata, M.4    Ding, X.5    Kawanishi, S.6
  • 103
    • 79952249828 scopus 로고    scopus 로고
    • Nitrative and oxidative DNA damage as potential survival biomarkers for nasopharyngeal carcinoma
    • Huang, Y.J.; Zhang, B.B.; Ma, N.; Murata, M.; Tang, A.Z.; Huang, G.W. Nitrative and oxidative DNA damage as potential survival biomarkers for nasopharyngeal carcinoma. Med. Oncol. 2011, 28, 377-384.
    • (2011) Med. Oncol , vol.28 , pp. 377-384
    • Huang, Y.J.1    Zhang, B.B.2    Ma, N.3    Murata, M.4    Tang, A.Z.5    Huang, G.W.6
  • 104
    • 42549120764 scopus 로고    scopus 로고
    • Reactive nitrogen species-dependent DNA damage in ebv-associated nasopharyngeal carcinoma: The relation to stat3 activation and egfr expression
    • Ma, N.; Kawanishi, M.; Hiraku, Y.; Murata, M.; Huang, G.W.; Huang, Y.; Luo, D.Z.; Mo, W.G.; Fukui, Y.; Kawanishi, S. Reactive nitrogen species-dependent DNA damage in ebv-associated nasopharyngeal carcinoma: The relation to stat3 activation and egfr expression. Int. J. Cancer 2008, 122, 2517-2525.
    • (2008) Int. J. Cancer , vol.122 , pp. 2517-2525
    • Ma, N.1    Kawanishi, M.2    Hiraku, Y.3    Murata, M.4    Huang, G.W.5    Huang, Y.6    Luo, D.Z.7    Mo, W.G.8    Fukui, Y.9    Kawanishi, S.10
  • 109
    • 84903825894 scopus 로고    scopus 로고
    • Formation of the nitrative DNA lesion 8-nitroguanine is associated with asbestos contents in human lung tissues: A pilot study
    • Hiraku, Y.; Sakai, K.; Shibata, E.; Kamijima, M.; Hisanaga, N.; Ma, N.; Kawanishi, S.; Murata, M. Formation of the nitrative DNA lesion 8-nitroguanine is associated with asbestos contents in human lung tissues: A pilot study. J. Occup. Health 2014, 56, 186-196.
    • (2014) J. Occup. Health , vol.56 , pp. 186-196
    • Hiraku, Y.1    Sakai, K.2    Shibata, E.3    Kamijima, M.4    Hisanaga, N.5    Ma, N.6    Kawanishi, S.7    Murata, M.8
  • 111
    • 0348049994 scopus 로고    scopus 로고
    • Immune activation and chronic inflammation as the cause of malignancy in oral lichen planus: Is there any evidence ?
    • Mignogna, M.D.; Fedele, S.; Lo Russo, L.; Lo Muzio, L.; Bucci, E. Immune activation and chronic inflammation as the cause of malignancy in oral lichen planus: Is there any evidence ? Oral. Oncol. 2004, 40, 120-130.
    • (2004) Oral. Oncol , vol.40 , pp. 120-130
    • Mignogna, M.D.1    Fedele, S.2    Lo Russo, L.3    Lo Muzio, L.4    Bucci, E.5
  • 113
    • 31544452756 scopus 로고    scopus 로고
    • 8-Nitroguanine formation in oral leukoplakia, a premalignant lesion
    • Ma, N.; Tagawa, T.; Hiraku, Y.; Murata, M.; Ding, X.; Kawanishi, S. 8-Nitroguanine formation in oral leukoplakia, a premalignant lesion. Nitric Oxide 2006, 14, 137-143.
    • (2006) Nitric Oxide , vol.14 , pp. 137-143
    • Ma, N.1    Tagawa, T.2    Hiraku, Y.3    Murata, M.4    Ding, X.5    Kawanishi, S.6
  • 114
    • 0025167285 scopus 로고
    • Increased risk of large-bowel cancer in Crohn’s disease with colonic involvement
    • Ekbom, A.; Helmick, C.; Zack, M.; Adami, H.O. Increased risk of large-bowel cancer in Crohn’s disease with colonic involvement. Lancet 1990, 336, 357-359.
    • (1990) Lancet , vol.336 , pp. 357-359
    • Ekbom, A.1    Helmick, C.2    Zack, M.3    Adami, H.O.4
  • 117
    • 28444449065 scopus 로고    scopus 로고
    • Liver stem cells: Implications for hepatocarcinogenesis
    • Alison, M.R. Liver stem cells: Implications for hepatocarcinogenesis. Stem Cell Rev. 2005, 1, 253-260.
    • (2005) Stem Cell Rev , vol.1 , pp. 253-260
    • Alison, M.R.1
  • 118
    • 55549131565 scopus 로고    scopus 로고
    • Inflammation as the primary aetiological agent of human prostate cancer: A stem cell connection?
    • Maitland, N.J.; Collins, A.T. Inflammation as the primary aetiological agent of human prostate cancer: A stem cell connection? J. Cell Biochem. 2008, 105, 931-939.
    • (2008) J. Cell Biochem , vol.105 , pp. 931-939
    • Maitland, N.J.1    Collins, A.T.2
  • 119
    • 42549099061 scopus 로고    scopus 로고
    • The cancer stem cell hypothesis: In search of definitions, markers, and relevance
    • Shipitsin, M.; Polyak, K. The cancer stem cell hypothesis: In search of definitions, markers, and relevance. Lab. Investig. 2008, 88, 459-463.
    • (2008) Lab. Investig , vol.88 , pp. 459-463
    • Shipitsin, M.1    Polyak, K.2
  • 123
    • 84860347162 scopus 로고    scopus 로고
    • Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44+ human breast cancer cells
    • Croker, A.K.; Allan, A.L. Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44+ human breast cancer cells. Breast Cancer Res. Treat. 2012, 133, 75-87.
    • (2012) Breast Cancer Res. Treat , vol.133 , pp. 75-87
    • Croker, A.K.1    Allan, A.L.2
  • 125
    • 79952528125 scopus 로고    scopus 로고
    • CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc− and thereby promotes tumor growth
    • Ishimoto, T.; Nagano, O.; Yae, T.; Tamada, M.; Motohara, T.; Oshima, H.; Oshima, M.; Ikeda, T.; Asaba, R.; Yagi, H., et al. CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc− and thereby promotes tumor growth. Cancer Cell 2011, 19, 387-400.
    • (2011) Cancer Cell , vol.19 , pp. 387-400
    • Ishimoto, T.1    Nagano, O.2    Yae, T.3    Tamada, M.4    Motohara, T.5    Oshima, H.6    Oshima, M.7    Ikeda, T.8    Asaba, R.9    Yagi, H.10
  • 126
    • 84859829553 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer stem cells
    • Shi, X.; Zhang, Y.; Zheng, J.; Pan, J. Reactive oxygen species in cancer stem cells. Antioxid. Redox Signal. 2012, 16, 1215-1228.
    • (2012) Antioxid. Redox Signal , vol.16 , pp. 1215-1228
    • Shi, X.1    Zhang, Y.2    Zheng, J.3    Pan, J.4
  • 127
    • 34548140496 scopus 로고    scopus 로고
    • An epigenetic perspective on the free radical theory of development
    • Hitchler, M.J.; Domann, F.E. An epigenetic perspective on the free radical theory of development. Free Radic. Biol. Med. 2007, 43, 1023-1036.
    • (2007) Free Radic. Biol. Med , vol.43 , pp. 1023-1036
    • Hitchler, M.J.1    Domann, F.E.2
  • 129
    • 84899141256 scopus 로고    scopus 로고
    • MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress
    • Laget, S.; Miotto, B.; Chin, H.G.; Esteve, P.O.; Roberts, R.J.; Pradhan, S.; Defossez, P.A. MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress. Epigenetics 2014, 9, 546-556.
    • (2014) Epigenetics , vol.9 , pp. 546-556
    • Laget, S.1    Miotto, B.2    Chin, H.G.3    Esteve, P.O.4    Roberts, R.J.5    Pradhan, S.6    Defossez, P.A.7
  • 131
    • 38149032931 scopus 로고    scopus 로고
    • IL-6 enhances the nuclear translocation of DNA cytosine-5-methyltransferase 1 (DNMT1) via phosphorylation of the nuclear localization sequence by the AKT kinase
    • Hodge, D.R.; Cho, E.; Copeland, T.D.; Guszczynski, T.; Yang, E.; Seth, A.K.; Farrar, W.L. IL-6 enhances the nuclear translocation of DNA cytosine-5-methyltransferase 1 (DNMT1) via phosphorylation of the nuclear localization sequence by the AKT kinase. Cancer Genomics Proteomics 2007, 4, 387-398.
    • (2007) Cancer Genomics Proteomics , vol.4 , pp. 387-398
    • Hodge, D.R.1    Cho, E.2    Copeland, T.D.3    Guszczynski, T.4    Yang, E.5    Seth, A.K.6    Farrar, W.L.7
  • 132
    • 84867322245 scopus 로고    scopus 로고
    • IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer
    • Li, Y.; Deuring, J.; Peppelenbosch, M.P.; Kuipers, E.J.; de Haar, C.; van der Woude, C.J. IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer. Carcinogenesis 2012, 33, 1889-1896.
    • (2012) Carcinogenesis , vol.33 , pp. 1889-1896
    • Li, Y.1    Deuring, J.2    Peppelenbosch, M.P.3    Kuipers, E.J.4    De Haar, C.5    Van Der Woude, C.J.6
  • 133
    • 79953131277 scopus 로고    scopus 로고
    • Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation
    • Thaler, R.; Agsten, M.; Spitzer, S.; Paschalis, E.P.; Karlic, H.; Klaushofer, K.; Varga, F. Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation. J. Biol. Chem. 2007, 286, 5578-5588.
    • (2007) J. Biol. Chem , vol.286 , pp. 5578-5588
    • Thaler, R.1    Agsten, M.2    Spitzer, S.3    Paschalis, E.P.4    Karlic, H.5    Klaushofer, K.6    Varga, F.7
  • 134
    • 63449133614 scopus 로고    scopus 로고
    • Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia
    • Niller, H.H.; Wolf, H.; Minarovits, J. Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia. Semin. Cancer Biol. 2009, 19, 158-164.
    • (2009) Semin. Cancer Biol , vol.19 , pp. 158-164
    • Niller, H.H.1    Wolf, H.2    Minarovits, J.3
  • 135
    • 78651366854 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of Myocardin in human nasopharyngeal carcinoma
    • Chen, F.; Mo, Y.; Ding, H.; Xiao, X.; Wang, S.Y.; Huang, G.; Zhang, Z.; Wang, S.Z. Frequent epigenetic inactivation of Myocardin in human nasopharyngeal carcinoma. Head Neck 2011, 33, 54-59.
    • (2011) Head Neck , vol.33 , pp. 54-59
    • Chen, F.1    Mo, Y.2    Ding, H.3    Xiao, X.4    Wang, S.Y.5    Huang, G.6    Zhang, Z.7    Wang, S.Z.8
  • 136
    • 79959812634 scopus 로고    scopus 로고
    • CDH4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma
    • Du, C.; Huang, T.; Sun, D.; Mo, Y.; Feng, H.; Zhou, X.; Xiao, X.; Yu, N.; Hou, B.; Huang, G., et al. CDH4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma. Cancer Lett. 2011, 309, 54-61.
    • (2011) Cancer Lett , vol.309 , pp. 54-61
    • Du, C.1    Huang, T.2    Sun, D.3    Mo, Y.4    Feng, H.5    Zhou, X.6    Xiao, X.7    Yu, N.8    Hou, B.9    Huang, G.10
  • 137
    • 84863100689 scopus 로고    scopus 로고
    • Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma
    • Mo, Y.; Midorikawa, K.; Zhang, Z.; Zhou, X.; Ma, N.; Huang, G.; Hiraku, Y.; Oikawa, S.; Murata, M. Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma. Cancer Lett. 2012, 323, 147-154.
    • (2012) Cancer Lett , vol.323 , pp. 147-154
    • Mo, Y.1    Midorikawa, K.2    Zhang, Z.3    Zhou, X.4    Ma, N.5    Huang, G.6    Hiraku, Y.7    Oikawa, S.8    Murata, M.9
  • 138
    • 78049518977 scopus 로고    scopus 로고
    • TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma
    • Wang, S.; Xiao, X.; Zhou, X.; Huang, T.; Du, C.; Yu, N.; Mo, Y.; Lin, L.; Zhang, J.; Ma, N., et al. TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma. BMC Cancer 2010, 10, 617.
    • (2010) BMC Cancer , vol.10 , pp. 617
    • Wang, S.1    Xiao, X.2    Zhou, X.3    Huang, T.4    Du, C.5    Yu, N.6    Mo, Y.7    Lin, L.8    Zhang, J.9    Ma, N.10
  • 139
    • 33845400874 scopus 로고    scopus 로고
    • Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma
    • Zhang, Z.; Sun, D.; van, D. N.; Tang, A.; Hu, L.; Huang, G. Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. Int. J. Cancer 2007, 120, 32-38.
    • (2007) Int. J. Cancer , vol.120 , pp. 32-38
    • Zhang, Z.1    Sun, D.2    Van, D.N.3    Tang, A.4    Hu, L.5    Huang, G.6
  • 141
    • 84883586337 scopus 로고    scopus 로고
    • Environmental factors and unhealthy lifestyle influence oxidative stress in humans—An overview
    • Aseervatham, G.S.; Sivasudha, T.; Jeyadevi, R.; Arul Ananth, D. Environmental factors and unhealthy lifestyle influence oxidative stress in humans—An overview. Environ. Sci. Pollut. Res. Int. 2013, 20, 4356-4369.
    • (2013) Environ. Sci. Pollut. Res. Int , vol.20 , pp. 4356-4369
    • Aseervatham, G.S.1    Sivasudha, T.2    Jeyadevi, R.3    Arul Ananth, D.4
  • 142
    • 0032780281 scopus 로고    scopus 로고
    • Lipid peroxidation and tissue damage
    • Mylonas, C.; Kouretas, D. Lipid peroxidation and tissue damage. In Vivo (Athens, Greece) 1999, 13, 295-309.
    • (1999) Vivo (Athens, Greece) , vol.13 , pp. 295-309
    • Mylonas, C.1    Kouretas, D.2
  • 143
    • 84892163616 scopus 로고    scopus 로고
    • Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease
    • Giordano, S.; Darley-Usmar, V.; Zhang, J. Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease. Redox Biol. 2014, 2, 82-90.
    • (2014) Redox Biol , vol.2 , pp. 82-90
    • Giordano, S.1    Darley-Usmar, V.2    Zhang, J.3
  • 144
    • 84916941205 scopus 로고    scopus 로고
    • Inverse association between cancer and neurodegenerative disease: Review of the epidemiologic and biological evidence
    • Driver, J.A. Inverse association between cancer and neurodegenerative disease: Review of the epidemiologic and biological evidence. Biogerontology 2014, 15, 547-557.
    • (2014) Biogerontology , vol.15 , pp. 547-557
    • Driver, J.A.1


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