MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress

Epigenetics

Volumn 9, Issue 4, 2014, Pages 546-556

  Laget, Sophie ^a,b   Miotto, Benoit ^a   Chin, Hang Gyeong ^b   Estève, Pierre Olivier ^b   Roberts, Richard J ^b   Pradhan, Sriharsa ^b   Defossez, Pierre Antoine ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b NEW ENGLAND BIOLABS   (United States)

Author keywords

DNA methylation; DNMT1; MBD4; Oxidative stress; Transcription

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLOHEXIMIDE; DNA METHYLTRANSFERASE 1; METHYL CPG BINDING PROTEIN; METHYL CPG BINDING PROTEIN 4; NUCLEAR PROTEIN; PROTEIN MSH4; PROTEIN P21; UNCLASSIFIED DRUG; CDKN1A PROTEIN, HUMAN; CELL CYCLE PROTEIN; CHROMATIN; DEOXYRIBONUCLEASE; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; MBD4 PROTEIN, HUMAN; MSH4 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CPG ISLAND; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; GENE EXPRESSION; GENE REPRESSION; GENOME ANALYSIS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; METHYL DNA IMMUNOPRECIPITATION; NONHUMAN; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; CHLOROCEBUS AETHIOPS; CHROMATIN; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROMOTER REGION;

ANIMALS; CELL CYCLE PROTEINS; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CHROMATIN; CPG ISLANDS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA DAMAGE; DNA METHYLATION; ENDODEOXYRIBONUCLEASES; GENE EXPRESSION REGULATION; HUMANS; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC;

EID: 84899141256     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.27695     Document Type: Article

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