Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: Evidence for neutrophil-mediated hydroxylation, nitration, and chlorination

Critical Care Medicine

Volumn 27, Issue 9, 1999, Pages 1738-1744

  Lamb, Nicholas J ^a   Gutteridge, John M C ^a   Baker, Cathy ^a   Evans, Timothy W ^a   Quinlan, Gregory J ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Acute respiratory distress syndrome; Bronchoalveolar lavage; Chlorotyrosine; Hydroxyl radical; Neutrophils; Oxidative damage; Peroxynitrite

Indexed keywords

3 NITROTYROSINE; CELL PROTEIN; CHLOROTYROSINE; MYELOPEROXIDASE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ACUTE RESPIRATORY TRACT DISEASE; ADULT; AGED; ARTICLE; CHLORINATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROXYLATION; LUNG FLUID; LUNG LAVAGE; LUNG VENTILATION; MALE; NITRATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; HYDROXYL RADICAL; HYDROXYLATION; HYPOCHLOROUS ACID; LINEAR MODELS; MALE; MIDDLE AGED; NEUTROPHIL ACTIVATION; NEUTROPHILS; NITRATES; OXIDANTS; OXIDATIVE STRESS; PROTEINS; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; STATISTICS, NONPARAMETRIC; TYROSINE;

EID: 0032880537     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199909000-00007     Document Type: Article

References (36)

1. 1. Bernard CR, Artigas A, Brigham KL, et al: The American-European consensus conference on ARDS: Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994; 149:818-824
2. 2. Curzen NP, Haslett C, Evans TW: Spectrum of disease. In: ARDS, Acute Respiratory Distress in Adults. Evans TW, Haslett C (Eds). London, Chapman & Hall, 1996, pp 25-35
3. 3. St John RC, Dorinsky PM: An overview of multiple organ dysfunction syndrome. J Lab Clin Med 1994; 124:478-483
4. 4. Matthay MA: The adult respiratory distress syndrome: Definition and prognosis. Clin Chest Med 1990; 11:575-580
5. 5. Dorinsky PM, Gadek JE: Multiple organ failure. Clin Chest Med 1990; 11:581-591
6. 6. Richard C, Lemonnier F, Thibault M, et al: Vitamin E defiency and lipoperoxidation during adult respiratory distress syndrome. Crit Care Med 1990; 18:4-9
7. 7. Quinlan GJ, Lamb NJ, Evans TW, et al: Plasma fatty acid changes and increased lipid peroxidation in patients with adult respiratory distress syndrome. Crit Care Med 1996; 24:241-246
8. 8. Quinlan GJ, Evans TW, Gutteridge JMC: Oxidative damage to plasma proteins in adult respiratory distress syndrome. Free Radic Res 1994; 20:289-298
9. 9. Cross CE, Forte T, Stocker R, et al: Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome. J Lab Clin Med 1990; 115: 396-404
10. 10. Gutteridge JMC, Quinlan GJ, Mumby S, et al: Primary plasma antioxidants in adult respiratory distress syndrome patients: Changes in iron-oxidising, iron-binding and free radical-scavenging proteins. J Lab Clin Med 1994; 124:263-273
11. 11. Gutteridge JMC, Quinlan GJ, Evans TW: Transient iron overload with bleomycin detectable iron in the plasma of patients with adult respiratory distress syndrome. Thorax 1994; 49:707-710
12. 12. Cantin A, North S, Hubbard R, et al: Normal alveolar lining fluid contains high levels of glutathione. J Appl Physiol 1987; 63:152-157
13. 13. Bunnell E, Pacht ER: Oxidised glutathione is increased in the alveolar fluid of patients with adult respiratory distress syndrome. Am Rev Respir Dis 1993; 148:1174-1178
14. 14. Cochrane CG, Spragg RG Revak SD, et al: The presence of neutrophil elastase and evidence of oxidation activity in bronochoalveolar lavage fluid of patients with adult respiratory distress syndrome. Am Rev Respir Dis 1983; 127:525-527
15. 15. Quinlan GJ, Lamb NJ, Tilly R, et al: Plasma hypoxanthine levels in ARDS: Implications for oxidative stress, morbidity and mortality. Am J Respir Crit Care Med 1997; 155: 479-484
16. 16. Karam LR, Bergtold DS, Simic MG: Biomarkers of OH radical damage in vivo. Free Radic Res Commun 1991; 12:11-16
17. 17. Sun JZ, Kaur H, Halliwell B, et al: Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo: Direct evidence for a pathogenic role of the hydroxyl radical in mycardial stunning. Circ Res 1993; 73:534-549
18. 18. Ischiropoulos H, Zhu L, Chen J, et al: Peroxynitrite mediated tyrosine nitration catalysed by superoxide dismutase. Arch Biochem Biopyhs 1992; 298:431-437
19. 19. Domigan NM, Charlton TS, Duncan MW, et al: Chlorination of tyrosyl residues in peptides by myloperoxidase and human neutrophils. J Biol Chem 1995; 270:16542-16548
20. 20. Murray JF, Matthay MA, Luce JM, et al: An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 1988; 138:720-723
21. 21. Ketting D, Wadman SK, Spaapen LJ, et al: Gas chromatography method for the separation of amino acid enantiomers in plasma and urine: Application in a case of short bowel syndrome. Clin Chim Acta 1991; 204: 79-86
22. 22. van der Vliet A, O'Neil CA, Halliwell B, et al: Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite: Evidence for hydroxyl radical production peroxynitrite. FEEBS Lett 1994; 339:89-92
23. 23. Turner JS, Potgieter PD, Linton DM: Systems for scoring severity of illness in intensive care. S Afr Med J 1989; 76:17-20
24. 24. Baouali AB, Aube H, Maupoil V, et al: Plasma lipid peroxidation in critically ill patients: Importance of mechanical ventilation. Free Rad Biol Med 1993; 16:223-227
25. 25. Gutteridge JMC, Mumby S, Quinlan GJ, et al: Pro-oxidant iron is present in human pulmonary epithelial lining fluid: implications for oxidative stress in the lung. Biochem Biophys Res Commun 1996; 220:1024-1027
26. 26. Baldwin SR, Simon RH, Grum CM, et al: Oxidant activity in the expired breath of patients with adult respiratory distress syndrome. Lancet 1986; i:11-14
27. 27. Weiss S: Tissue destruction by neutrophils. N Engl J Med 1989; 320:365-376
28. 28. Candeias LP, Stratford MR, Wardman P: Formation of hydroxyl radicals on reaction of hypochlorous acid with ferrocyanide, a model iron (II) complex. Free Radic Res 1994; 20:241-249
29. 29. Candeias LP, Patel KB, Stratford MR, et al: Free hydroxyl radicals are formed on reaction between the neutrophil derived species, superoxide anion and hypochlorous acid. FEBS Lett 1993; 333:151-153
30. 30. Blough NV, Zafiriou OC: Reaction of superoxide with nitric oxide to form peroxynitrite in alkaline aqueous solutions. Inorg Chem 1985; 24:3502-3504
31. 31. Kooy N, Randall J, Ye Y, et al: Evidence for in vivo peroxynitrite production in human acute lung injury. Am J Respir Crit Care Med 1995; 151:1250-1254
32. 32. Beckman J, Beckman T, Chan J, et al: Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990; 87:1620-1624
33. 33. Eiserich JP, Cross CE, Jones AD, et al: Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid: A novel mechanism for nitric oxide-mediated protein modification. J Biol Chem 1996; 271: 19199-19208
34. 34. Weiland JE, Davies WB, Holler JF: Lung neutrophils in the adult respiratory distress syndrome: Clinical and pathological significance. Am Rev Respir Dis 1986; 14: 218-225
35. 35. Babior BM: The respiratory burst of phagocytes. J Clin Invest 1984; 73:599-601
36. 36. Stadtman ER: Metal ion catalysed oxidation of proteins: Biochemical mechanisms and biological consequences. Free Radic Biol Med 1990; 9:315-325