New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases

Biomolecules

Volumn 4, Issue 3, 2014, Pages 678-703

  Mitra, Joy ^a,b   Guerrero, Erika N ^a,c,d   Hegde, Pavana M ^a   Wang, Haibo ^a,b   Boldogh, Istvan ^e   Rao, Kosagi Sharaf ^c   Mitra, Sankar ^a   Hegde, Muralidhar L ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^c INSTITUTO DE INVESTIGACIONES CIENTÍFICAS Y SERVICIOS DE ALTA TECNOLOGÍA   (Panama)

^d ACHARYA NAGARJUNA UNIVERSITY   (India)

^e University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Alzheimer s disease; DNA base excision repair; Heavy metals; Metal homeostasis; Metal toxicity; Neurodegeneration; Parkinson s disease; Redox transition metals

Indexed keywords

AMYLOID PROTEIN; BER PROTEIN; CADMIUM; COPPER; FERRIC ION; LEAD; MANGANESE; MERCURY; METAL; REACTIVE OXYGEN METABOLITE; TRANSITION ELEMENT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; BLOOD BRAIN BARRIER; CELL CYCLE REGULATION; CENTRAL NERVOUS SYSTEM; DISEASE COURSE; DNA REPAIR; ENVIRONMENTAL EXPOSURE; FRIEDREICH ATAXIA; GENOMIC INSTABILITY; HEAVY METAL POISONING; HUMAN; HUNTINGTON CHOREA; NEOPLASM; NERVE DEGENERATION; NEUROLOGIC DISEASE; NEUROTOXICITY; NONHUMAN; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; PARKINSON DISEASE; PROTEIN AGGREGATION; REVIEW; WILSON DISEASE; XERODERMA PIGMENTOSUM; ANIMAL; DEGENERATIVE DISEASE; DNA DAMAGE; GENETICS; GENOME; METABOLISM; OXIDATION REDUCTION REACTION;

ANIMALS; DNA DAMAGE; DNA REPAIR; GENOME; HUMANS; METALS; NEURODEGENERATIVE DISEASES; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES;

EID: 84919786949     PISSN: None     EISSN: 2218273X     Source Type: Journal    
DOI: 10.3390/biom4030678     Document Type: Review

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