Proteomic identification of hippocampal proteins vulnerable to oxidative stress in excitotoxin-induced acute neuronal injury

Neurobiology of Disease

Volumn 43, Issue 3, 2011, Pages 706-714

  Furukawa, Ayako ^a   Kawamoto, Yoshiyuki ^b   Chiba, Yoichi ^a   Takei, Shiro ^a   Hasegawa Ishii, Sanae ^a   Kawamura, Noriko ^a   Yoshikawa, Keisuke ^a   Hosokawa, Masanori ^a   Oikawa, Shinji ^c   Kato, Masashi ^b   Shimada, Atsuyoshi ^a  

^a INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^b CHUBU UNIVERSITY   (Japan)

^c MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Carbonylated proteins; Excitotoxicity; Kainic acid; Oxidative stress; Proteomics

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALPHA INTERNEXIN; DNA; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 70 PROTEIN 4; HIPPOCAMPAL PROTEIN; KAINIC ACID; MITOCHONDRIAL PROTEIN; MITOFILIN; NERVE PROTEIN; PROTEIN 14 3 3; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN;

AMINO ACID SEQUENCE; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOPLASM; DENSITOMETRY; DNA DAMAGE; EPILEPTIC STATE; EXCITOTOXICITY; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIQUID CHROMATOGRAPHY; MALE; MITOCHONDRION SWELLING; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; ROUGH ENDOPLASMIC RETICULUM; ROUGH ENDOPLASMIC RETICULUM SWELLING; TANDEM MASS SPECTROMETRY; TRANSMISSION ELECTRON MICROSCOPY; TWO DIMENSIONAL FLUORESCENCE DIFFERENCE GEL ELECTROPHORESIS; TWO DIMENSIONAL GEL ELECTROPHORESIS; TWO DIMENSIONAL OXYBLOT;

ACUTE DISEASE; ANIMALS; CELL DEATH; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; KAINIC ACID; MALE; NERVE TISSUE PROTEINS; NEURONS; NEUROTOXINS; OXIDATIVE STRESS; PROTEOMICS; RATS; RATS, WISTAR; STATUS EPILEPTICUS;

EID: 79960268624     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.05.024     Document Type: Article

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