Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation

Journal of Biological Chemistry

Volumn 286, Issue 7, 2011, Pages 5578-5588

  Thaler, Roman ^a   Agsten, Marlies ^a   Spitzer, Silvia ^a   Paschalis, Eleftherios P ^a   Karlic, Heidrun ^a   Klaushofer, Klaus ^a   Varga, Franz ^a  

^a HANUSCH HOSPITAL   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

AFTER-TREATMENT; BONE DEVELOPMENT; BONE MATRIX; BONE METABOLISM; CARDIO-VASCULAR DISEASE; CHRONIC RENAL FAILURE; CROSSLINKER; DNA METHYLATION; DOWN-REGULATION; GENE ARRAYS; HELICASES; HOMOCYSTEINES; IMMUNOBLOTS; INTERLEUKIN-6; JANUS KINASE 2; LYSYL OXIDASE; MC3T3-E1 CELL; METHYLATION ANALYSIS; METHYLTRANSFERASES; MRNA EXPRESSION; NEW MECHANISMS; QUANTITATIVE RT-PCR; RISK FACTORS; SERUM LEVELS; SIGNAL TRANSDUCTION PATHWAYS; UP-REGULATION;

ALKYLATION; BONE; COLLAGEN; DISEASES; DNA; ENZYME INHIBITION; ENZYMES; GENES; METHYLATION; NUCLEIC ACIDS; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION; TRANSCRIPTION FACTORS; VIRUSES;

IMMUNOLOGY;

COLLAGEN; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; HOMOCYSTEINE; INTERLEUKIN 6; JANUS KINASE 2; MESSENGER RNA; PROTEIN LYSINE 6 OXIDASE; TRANSCRIPTION FACTOR FLI 1;

ANIMAL CELL; ARTICLE; BONE MATRIX; CONTROLLED STUDY; CROSS LINKING; DNA METHYLATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; EPIGENETICS; GENE EXPRESSION; GENETIC ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA HELICASES; DNA METHYLATION; EPIGENESIS, GENETIC; EXTRACELLULAR MATRIX PROTEINS; HOMOCYSTEINE; INTERLEUKIN-6; JANUS KINASE 2; MICE; OSTEOGENESIS; PROMOTER REGIONS, GENETIC; PROTEIN-LYSINE 6-OXIDASE; PROTO-ONCOGENE PROTEIN C-FLI-1;

FRIEND MURINE LEUKEMIA VIRUS;

EID: 79953131277     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.166181     Document Type: Article

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