-
1
-
-
0036212849
-
Innate immune recognition
-
Janeway CA Jr, Medzhitov R. Innate immune recognition. Annu Rev Immunol (2002) 20:197-216. doi:10.1146/annurev.immunol.20.083001.084359
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 197-216
-
-
Janeway Jr, C.A.1
Medzhitov, R.2
-
2
-
-
0034041033
-
Immunobiology of dendritic cells
-
Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, et al. Immunobiology of dendritic cells. Annu Rev Immunol (2000) 18:767-811. doi:10.1146/annurev.immunol.18.1.767
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 767-811
-
-
Banchereau, J.1
Briere, F.2
Caux, C.3
Davoust, J.4
Lebecque, S.5
Liu, Y.J.6
-
3
-
-
84899084503
-
Vaccines against tropical parasitic diseases: a persisting answer to a persisting problem
-
Sacks DL. Vaccines against tropical parasitic diseases: a persisting answer to a persisting problem. Nat Immunol (2014) 15:403-5. doi:10.1038/ni.2853
-
(2014)
Nat Immunol
, vol.15
, pp. 403-405
-
-
Sacks, D.L.1
-
4
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Regulatory T cells and immune tolerance. Cell (2008) 133:775-87. doi:10.1016/j.cell.2008.05.009
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
5
-
-
5044220930
-
IDO expression by dendritic cells: tolerance and tryptophan catabolism
-
Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol (2004) 4:762-74. doi:10.1038/nri1457
-
(2004)
NatRevImmunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
6
-
-
19344377474
-
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2 3-dioxygenase
-
Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, et al. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity (2005) 22:633-42. doi:10.1016/j.immuni.2005.03.013
-
(2005)
Immunity
, vol.22
, pp. 633-642
-
-
Munn, D.H.1
Sharma, M.D.2
Baban, B.3
Harding, H.P.4
Zhang, Y.5
Ron, D.6
-
7
-
-
1042291130
-
T cell apoptosis by kynurenines
-
Fallarino F, Grohmann U, Vacca C, Orabona C, Spreca A, Fioretti MC, et al. T cell apoptosis by kynurenines. Adv Exp Med Biol (2003) 527:183-90. doi:10.1007/978-1-4615-0135-0_21
-
(2003)
Adv Exp Med Biol
, vol.527
, pp. 183-190
-
-
Fallarino, F.1
Grohmann, U.2
Vacca, C.3
Orabona, C.4
Spreca, A.5
Fioretti, M.C.6
-
8
-
-
33751563152
-
Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals
-
Boonstra A, Rajsbaum R, Holman M, Marques R, Asselin-Paturel C, Pereira JP, et al. Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol (2006) 177:7551-8. doi:10.4049/jimmunol.177.11.7551
-
(2006)
J Immunol
, vol.177
, pp. 7551-7558
-
-
Boonstra, A.1
Rajsbaum, R.2
Holman, M.3
Marques, R.4
Asselin-Paturel, C.5
Pereira, J.P.6
-
9
-
-
0022465625
-
Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth
-
Kehrl JH, Wakefield LM, Roberts AB, Jakowlew S, Alvarez-Mon M, Derynck R, et al. Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth. J Exp Med (1986) 163:1037-50. doi:10.1084/jem.163.5.1037
-
(1986)
J Exp Med
, vol.163
, pp. 1037-1050
-
-
Kehrl, J.H.1
Wakefield, L.M.2
Roberts, A.B.3
Jakowlew, S.4
Alvarez-Mon, M.5
Derynck, R.6
-
10
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
-
Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, et al. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature (1992) 359:693-9. doi:10.1038/359693a0
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
Ormsby, I.2
Kier, A.B.3
Pawlowski, S.4
Diebold, R.J.5
Yin, M.6
-
11
-
-
0036197923
-
Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
-
Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK. Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity (2002) 16:219-30. doi:10.1016/S1074-7613(02)00274-1
-
(2002)
Immunity
, vol.16
, pp. 219-230
-
-
Mizoguchi, A.1
Mizoguchi, E.2
Takedatsu, H.3
Blumberg, R.S.4
Bhan, A.K.5
-
12
-
-
84864588491
-
IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c(+) cell populations during visceral leishmaniasis
-
Owens BM, Beattie L, Moore JW, Brown N, Mann JL, Dalton JE, et al. IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c(+) cell populations during visceral leishmaniasis. PLoS Pathog (2012) 8:e1002827. doi:10.1371/journal.ppat.1002827
-
(2012)
PLoS Pathog
, vol.8
-
-
Owens, B.M.1
Beattie, L.2
Moore, J.W.3
Brown, N.4
Mann, J.L.5
Dalton, J.E.6
-
13
-
-
10344239885
-
Stromal cells direct local differentiation of regulatory dendritic cells
-
Svensson M, Maroof A, Ato M, Kaye PM. Stromal cells direct local differentiation of regulatory dendritic cells. Immunity (2004) 21:805-16. doi:10.1016/j.immuni.2004.10.012
-
(2004)
Immunity
, vol.21
, pp. 805-816
-
-
Svensson, M.1
Maroof, A.2
Ato, M.3
Kaye, P.M.4
-
14
-
-
40449105455
-
Plasmodium infection and endotoxic shock induce the expansion of regulatory dendritic cells
-
Wong KA, Rodriguez A. Plasmodium infection and endotoxic shock induce the expansion of regulatory dendritic cells. J Immunol (2008) 180:716-26. doi:10.4049/jimmunol.180.2.716
-
(2008)
J Immunol
, vol.180
, pp. 716-726
-
-
Wong, K.A.1
Rodriguez, A.2
-
15
-
-
84866511135
-
The diverse roles of monocytes in inflammation caused by protozoan parasitic diseases
-
Sheel M, Engwerda CR. The diverse roles of monocytes in inflammation caused by protozoan parasitic diseases. Trends Parasitol (2012) 28:408-16. doi:10.1016/j.pt.2012.07.008
-
(2012)
Trends Parasitol
, vol.28
, pp. 408-416
-
-
Sheel, M.1
Engwerda, C.R.2
-
16
-
-
84875544506
-
Interleukin-4- and interleukin-13-mediated alternatively activated macrophages roles in homeostasis and disease.
-
Van Dyken SJ, Locksley RM. Interleukin-4- and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease. Annu Rev Immunol (2013) 31:317-43. doi:10.1146/annurev-immunol-032712-095906
-
(2013)
Annu Rev Immunol
, vol.31
-
-
Van Dyken, S.J.1
Locksley, R.M.2
-
17
-
-
34247104151
-
Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania
-
Leon B, Lopez-Bravo M, Ardavin C. Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity (2007) 26:519-31. doi:10.1016/j.immuni.2007.01.017
-
(2007)
Immunity
, vol.26
, pp. 519-531
-
-
Leon, B.1
Lopez-Bravo, M.2
Ardavin, C.3
-
18
-
-
0033571729
-
Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice
-
Sato N, Kuziel WA, Melby PC, Reddick RL, Kostecki V, Zhao W, et al. Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice. J Immunol (1999) 163:5519-25.
-
(1999)
J Immunol
, vol.163
, pp. 5519-5525
-
-
Sato, N.1
Kuziel, W.A.2
Melby, P.C.3
Reddick, R.L.4
Kostecki, V.5
Zhao, W.6
-
19
-
-
77958124602
-
Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2 IFN-gamma and MyD88 signaling
-
Bosschaerts T, Guilliams M, Stijlemans B, Morias Y, Engel D, Tacke F, et al. Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling. PLoS Pathog (2010) 6:e1001045. doi:10.1371/journal.ppat.1001045
-
(2010)
PLoS Pathog
, vol.6
-
-
Bosschaerts, T.1
Guilliams, M.2
Stijlemans, B.3
Morias, Y.4
Engel, D.5
Tacke, F.6
-
20
-
-
60549106289
-
IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection
-
Guilliams M, Movahedi K, Bosschaerts T, VandenDriessche T, Chuah MK, Herin M, et al. IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection. J Immunol (2009) 182:1107-18. doi:10.4049/jimmunol.182.2.1107
-
(2009)
J Immunol
, vol.182
, pp. 1107-1118
-
-
Guilliams, M.1
Movahedi, K.2
Bosschaerts, T.3
VandenDriessche, T.4
Chuah, M.K.5
Herin, M.6
-
21
-
-
70449574101
-
Local suppression of T cell responses by arginase-induced l-arginine depletion in nonhealing leishmaniasis
-
Modolell M, Choi BS, Ryan RO, Hancock M, Titus RG, Abebe T, et al. Local suppression of T cell responses by arginase-induced l-arginine depletion in nonhealing leishmaniasis. PLoS Negl Trop Dis (2009) 3:e480. doi:10.1371/journal.pntd.0000480
-
(2009)
PLoS Negl Trop Dis
, vol.3
-
-
Modolell, M.1
Choi, B.S.2
Ryan, R.O.3
Hancock, M.4
Titus, R.G.5
Abebe, T.6
-
22
-
-
56349093356
-
Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens
-
El Kasmi KC, Qualls JE, Pesce JT, Smith AM, Thompson RW, Henao-Tamayo M, et al. Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens. Nat Immunol (2008) 9:1399-406. doi:10.1038/ni.1671
-
(2008)
Nat Immunol
, vol.9
, pp. 1399-1406
-
-
El Kasmi, K.C.1
Qualls, J.E.2
Pesce, J.T.3
Smith, A.M.4
Thompson, R.W.5
Henao-Tamayo, M.6
-
23
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25) Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol (1995) 155:1151-64.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
24
-
-
33746365086
-
The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells
-
Shevach EM, DiPaolo RA, Andersson J, Zhao DM, Stephens GL, Thornton AM. The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol Rev (2006) 212:60-73. doi:10.1111/j.0105-2896.2006.00415.x
-
(2006)
Immunol Rev
, vol.212
, pp. 60-73
-
-
Shevach, E.M.1
DiPaolo, R.A.2
Andersson, J.3
Zhao, D.M.4
Stephens, G.L.5
Thornton, A.M.6
-
25
-
-
85047692430
-
IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage
-
O'Garra A, Vieira PL, Vieira P, Goldfeld AE. IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest (2004) 114:1372-8. doi:10.1172/JCI200423215
-
(2004)
J Clin Invest
, vol.114
, pp. 1372-1378
-
-
O'Garra, A.1
Vieira, P.L.2
Vieira, P.3
Goldfeld, A.E.4
-
26
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: suppression of autoimmunee ncephalomyelitis
-
Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science (1994) 265:1237-40. doi:10.1126/science.7520605
-
(1994)
Science
, vol.265
, pp. 1237-1240
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
27
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen W, Jin W, Hardegen N, Lei KJ, Li L, Marinos N, et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med (2003) 198:1875-86. doi:10.1084/jem.20030152
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
-
28
-
-
34748873441
-
Regulatory T cells and infection a dangerous necessity.
-
Belkaid Y. Regulatory T cells and infection: a dangerous necessity. Nat Rev Immunol (2007) 7:875-88. doi:10.1038/nri2189
-
(2007)
Nat Rev Immunol
, vol.7
-
-
Belkaid, Y.1
-
29
-
-
36248976097
-
CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
-
Pandiyan P, Zheng L, Ishihara S, Reed J, Lenardo MJ. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat Immunol (2007) 8:1353-62. doi:10.1038/ni1536
-
(2007)
Nat Immunol
, vol.8
, pp. 1353-1362
-
-
Pandiyan, P.1
Zheng, L.2
Ishihara, S.3
Reed, J.4
Lenardo, M.J.5
-
30
-
-
70049113279
-
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner
-
Chaudhry A, Rudra D, Treuting P, Samstein RM, Liang Y, Kas A, et al. CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner. Science (2009) 326:986-91. doi:10.1126/science.1172702
-
(2009)
Science
, vol.326
, pp. 986-991
-
-
Chaudhry, A.1
Rudra, D.2
Treuting, P.3
Samstein, R.M.4
Liang, Y.5
Kas, A.6
-
31
-
-
65749103365
-
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
-
Koch MA, Tucker-Heard G, Perdue NR, Killebrew JR, Urdahl KB, Campbell DJ. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat Immunol (2009) 10:595-602. doi:10.1038/ni.1731
-
(2009)
Nat Immunol
, vol.10
, pp. 595-602
-
-
Koch, M.A.1
Tucker-Heard, G.2
Perdue, N.R.3
Killebrew, J.R.4
Urdahl, K.B.5
Campbell, D.J.6
-
32
-
-
79961151137
-
Foxp3+ follicular regulatory T cells control the germinal center response
-
Linterman MA, Pierson W, Lee SK, Kallies A, Kawamoto S, Rayner TF, et al. Foxp3+ follicular regulatory T cells control the germinal center response. Nat Med (2011) 17:975-82. doi:10.1038/nm.2425
-
(2011)
Nat Med
, vol.17
, pp. 975-982
-
-
Linterman, M.A.1
Pierson, W.2
Lee, S.K.3
Kallies, A.4
Kawamoto, S.5
Rayner, T.F.6
-
33
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
-
Zheng Y, Chaudhry A, Kas A, deRoos P, Kim JM, Chu TT, et al. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature (2009) 458:351-6. doi:10.1038/nature07674
-
(2009)
Nature
, vol.458
, pp. 351-356
-
-
Zheng, Y.1
Chaudhry, A.2
Kas, A.3
deRoos, P.4
Kim, J.M.5
Chu, T.T.6
-
34
-
-
84896704750
-
Homeostatic control of regulatory T cell diversity
-
Liston A, Gray DH. Homeostatic control of regulatory T cell diversity. Nat Rev Immunol (2014) 14:154-65. doi:10.1038/nri3605
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 154-165
-
-
Liston, A.1
Gray, D.H.2
-
35
-
-
84866483591
-
The cytokines interleukin 27 and interferon-gamma promote distinct Treg cell populations required to limit infection-induced pathology
-
Hall AO, Beiting DP, Tato C, John B, Oldenhove G, Lombana CG, et al. The cytokines interleukin 27 and interferon-gamma promote distinct Treg cell populations required to limit infection-induced pathology. Immunity (2012) 37:511-23. doi:10.1016/j.immuni.2012.06.014
-
(2012)
Immunity
, vol.37
, pp. 511-523
-
-
Hall, A.O.1
Beiting, D.P.2
Tato, C.3
John, B.4
Oldenhove, G.5
Lombana, C.G.6
-
36
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature (2002) 420:502-7. doi:10.1038/nature01152
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
37
-
-
33645077332
-
Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens
-
Suffia IJ, Reckling SK, Piccirillo CA, Goldszmid RS, Belkaid Y. Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens. J Exp Med (2006) 203:777-88. doi:10.1084/jem.20052056
-
(2006)
J Exp Med
, vol.203
, pp. 777-788
-
-
Suffia, I.J.1
Reckling, S.K.2
Piccirillo, C.A.3
Goldszmid, R.S.4
Belkaid, Y.5
-
38
-
-
1842455770
-
Escape of malaria parasites from host immunity requires CD4+ CD25+ regulatory T cells
-
Hisaeda H, Maekawa Y, Iwakawa D, Okada H, Himeno K, Kishihara K, et al. Escape of malaria parasites from host immunity requires CD4+ CD25+ regulatory T cells. Nat Med (2004) 10:29-30. doi:10.1038/nm975
-
(2004)
Nat Med
, vol.10
, pp. 29-30
-
-
Hisaeda, H.1
Maekawa, Y.2
Iwakawa, D.3
Okada, H.4
Himeno, K.5
Kishihara, K.6
-
39
-
-
24944466472
-
Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection
-
Walther M, Tongren JE, Andrews L, Korbel D, King E, Fletcher H, et al. Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity (2005) 23:287-96. doi:10.1016/j.immuni.2005.08.006
-
(2005)
Immunity
, vol.23
, pp. 287-296
-
-
Walther, M.1
Tongren, J.E.2
Andrews, L.3
Korbel, D.4
King, E.5
Fletcher, H.6
-
40
-
-
33947640163
-
Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice
-
Couper KN, Blount DG, de Souza JB, Suffia I, Belkaid Y, Riley EM. Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice. J Immunol (2007) 178:4136-46. doi:10.4049/jimmunol.178.7.4136
-
(2007)
J Immunol
, vol.178
, pp. 4136-4146
-
-
Couper, K.N.1
Blount, D.G.2
de Souza, J.B.3
Suffia, I.4
Belkaid, Y.5
Riley, E.M.6
-
41
-
-
34548319120
-
A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria
-
Amante FH, Stanley AC, Randall LM, Zhou Y, Haque A, McSweeney K, et al. A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria. Am J Pathol (2007) 171:548-59. doi:10.2353/ajpath.2007.061033
-
(2007)
Am J Pathol
, vol.171
, pp. 548-559
-
-
Amante, F.H.1
Stanley, A.C.2
Randall, L.M.3
Zhou, Y.4
Haque, A.5
McSweeney, K.6
-
42
-
-
34248345515
-
CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis
-
Nie CQ, Bernard NJ, Schofield L, Hansen DS. CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis. Infect Immun (2007) 75:2275-82. doi:10.1128/IAI.01783-06
-
(2007)
Infect Immun
, vol.75
, pp. 2275-2282
-
-
Nie, C.Q.1
Bernard, N.J.2
Schofield, L.3
Hansen, D.S.4
-
43
-
-
34249947689
-
Regulatory CD4+ CD25+ Foxp3+ T cells expand during experimental Plasmodium infection but do not prevent cerebral malaria
-
Vigario AM, Gorgette O, Dujardin HC, Cruz T, Cazenave PA, Six A, et al. Regulatory CD4+ CD25+ Foxp3+ T cells expand during experimental Plasmodium infection but do not prevent cerebral malaria. Int J Parasitol (2007) 37:963-73. doi:10.1016/j.ijpara.2007.01.004
-
(2007)
Int J Parasitol
, vol.37
, pp. 963-973
-
-
Vigario, A.M.1
Gorgette, O.2
Dujardin, H.C.3
Cruz, T.4
Cazenave, P.A.5
Six, A.6
-
44
-
-
33846423147
-
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
-
Lahl K, Loddenkemper C, Drouin C, Freyer J, Arnason J, Eberl G, et al. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J Exp Med (2007) 204:57-63. doi:10.1084/jem.20061852
-
(2007)
J Exp Med
, vol.204
, pp. 57-63
-
-
Lahl, K.1
Loddenkemper, C.2
Drouin, C.3
Freyer, J.4
Arnason, J.5
Eberl, G.6
-
45
-
-
78651321282
-
CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo
-
Haque A, Best SE, Amante FH, Mustafah S, Desbarrieres L, de Labastida F, et al. CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo. PLoS Pathog (2010) 6:e1001221. doi:10.1371/journal.ppat.1001221
-
(2010)
PLoS Pathog
, vol.6
-
-
Haque, A.1
Best, S.E.2
Amante, F.H.3
Mustafah, S.4
Desbarrieres, L.5
de Labastida, F.6
-
46
-
-
73349085916
-
Limited role of CD4+Foxp3+ regulatory T cells in the control of experimental cerebral malaria
-
Steeg C, Adler G, Sparwasser T, Fleischer B, Jacobs T. Limited role of CD4+Foxp3+ regulatory T cells in the control of experimental cerebral malaria. J Immunol (2009) 183:7014-22. doi:10.4049/jimmunol.0901422
-
(2009)
J Immunol
, vol.183
, pp. 7014-7022
-
-
Steeg, C.1
Adler, G.2
Sparwasser, T.3
Fleischer, B.4
Jacobs, T.5
-
47
-
-
34249678457
-
T(H)1 cells control themselves by producing interleukin-10
-
O'Garra A, Vieira P. T(H)1 cells control themselves by producing interleukin-10. Nat Rev Immunol (2007) 7:425-8. doi:10.1038/nri2097
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 425-428
-
-
O'Garra, A.1
Vieira, P.2
-
48
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva M, O'Garra A. The regulation of IL-10 production by immune cells. Nat Rev Immunol (2010) 10:170-81. doi:10.1038/nri2711
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
-
49
-
-
0024408824
-
Two types of mouse T helper cell IV Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
-
Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med (1989) 170:2081-95. doi:10.1084/jem.170.6.2081
-
(1989)
J Exp Med
, vol.170
, pp. 2081-2095
-
-
Fiorentino, D.F.1
Bond, M.W.2
Mosmann, T.R.3
-
50
-
-
0030584733
-
IL-12-induced IL-10 production by human T cells as a negative feedback for IL-12-induced immune responses
-
Meyaard L, Hovenkamp E, Otto SA, Miedema F. IL-12-induced IL-10 production by human T cells as a negative feedback for IL-12-induced immune responses. J Immunol (1996) 156:2776-82.
-
(1996)
J Immunol
, vol.156
, pp. 2776-2782
-
-
Meyaard, L.1
Hovenkamp, E.2
Otto, S.A.3
Miedema, F.4
-
51
-
-
0026727906
-
IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells
-
Yssel H, De Waal Malefyt R, Roncarolo MG, Abrams JS, Lahesmaa R, Spits H, et al. IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells. J Immunol (1992) 149:2378-84.
-
(1992)
J Immunol
, vol.149
, pp. 2378-2384
-
-
Yssel, H.1
De Waal Malefyt, R.2
Roncarolo, M.G.3
Abrams, J.S.4
Lahesmaa, R.5
Spits, H.6
-
52
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, et al.A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 389:737-42. doi:10.1038/39614
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
de Vries, J.E.6
-
53
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer JS, Silver JS, Laurence A, Porrett PM, Harris TH, Turka LA, et al. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol (2007) 8:1363-71. doi:10.1038/ni1537
-
(2007)
Nat Immunol
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
Porrett, P.M.4
Harris, T.H.5
Turka, L.A.6
-
54
-
-
33847144180
-
Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
-
Jankovic D, Kullberg MC, Feng CG, Goldszmid RS, Collazo CM, Wilson M, et al. Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J Exp Med (2007) 204:273-83. doi:10.1084/jem.20062175
-
(2007)
J Exp Med
, vol.204
, pp. 273-283
-
-
Jankovic, D.1
Kullberg, M.C.2
Feng, C.G.3
Goldszmid, R.S.4
Collazo, C.M.5
Wilson, M.6
-
55
-
-
33847163271
-
CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
-
Anderson CF, Oukka M, Kuchroo VJ, Sacks D. CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med (2007) 204:285-97. doi:10.1084/jem.20061886
-
(2007)
J Exp Med
, vol.204
, pp. 285-297
-
-
Anderson, C.F.1
Oukka, M.2
Kuchroo, V.J.3
Sacks, D.4
-
56
-
-
22144487678
-
A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis
-
Wilson EH, Wille-Reece U, Dzierszinski F, Hunter CA. A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis. J Neuroimmunol (2005) 165:63-74. doi:10.1016/j.jneuroim.2005.04.018
-
(2005)
J Neuroimmunol
, vol.165
, pp. 63-74
-
-
Wilson, E.H.1
Wille-Reece, U.2
Dzierszinski, F.3
Hunter, C.A.4
-
57
-
-
40349089873
-
IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection
-
Couper KN, Blount DG, Wilson MS, Hafalla JC, Belkaid Y, Kamanaka M, et al. IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. PLoS Pathog (2008) 4:e1000004. doi:10.1371/journal.ppat.1000004
-
(2008)
PLoS Pathog
, vol.4
-
-
Couper, K.N.1
Blount, D.G.2
Wilson, M.S.3
Hafalla, J.C.4
Belkaid, Y.5
Kamanaka, M.6
-
58
-
-
84856567798
-
IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: acritical mechanism for protection from severe immunopathology during malaria infection
-
do Rosario AP, Lamb T, Spence P, Stephens R, Lang A, Roers A, et al. IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. J Immunol (2012) 188:1178-90. doi:10.4049/jimmunol.1102755
-
(2012)
J Immunol
, vol.188
, pp. 1178-1190
-
-
do Rosario, A.P.1
Lamb, T.2
Spence, P.3
Stephens, R.4
Lang, A.5
Roers, A.6
-
59
-
-
0027930302
-
IL-10 mediates susceptibility to Trypanosoma cruzi infection
-
Reed SG, Brownell CE, Russo DM, Silva JS, Grabstein KH, Morrissey PJ. IL-10 mediates susceptibility to Trypanosoma cruzi infection. J Immunol (1994) 153:3135-40.
-
(1994)
J Immunol
, vol.153
, pp. 3135-3140
-
-
Reed, S.G.1
Brownell, C.E.2
Russo, D.M.3
Silva, J.S.4
Grabstein, K.H.5
Morrissey, P.J.6
-
60
-
-
84856013800
-
IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection
-
Roffe E, Rothfuchs AG, Santiago HC, Marino AP, Ribeiro-Gomes FL, Eckhaus M, et al. IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection. J Immunol (2012) 188:649-60. doi:10.4049/jimmunol.1003845
-
(2012)
J Immunol
, vol.188
, pp. 649-660
-
-
Roffe, E.1
Rothfuchs, A.G.2
Santiago, H.C.3
Marino, A.P.4
Ribeiro-Gomes, F.L.5
Eckhaus, M.6
-
61
-
-
0035877180
-
Relative contribution of interferon-gamma and interleukin-10 to resistance to murine African trypanosomosis
-
Namangala B, Noel W, De Baetselier P, Brys L, Beschin A. Relative contribution of interferon-gamma and interleukin-10 to resistance to murine African trypanosomosis. J Infect Dis (2001) 183:1794-800. doi:10.1086/320731
-
(2001)
J Infect Dis
, vol.183
, pp. 1794-1800
-
-
Namangala, B.1
Noel, W.2
De Baetselier, P.3
Brys, L.4
Beschin, A.5
-
62
-
-
34247350697
-
Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis
-
Nylen S, Maurya R, Eidsmo L, Manandhar KD, Sundar S, Sacks D. Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis. J Exp Med (2007) 204:805-17. doi:10.1084/jem.20061141
-
(2007)
J Exp Med
, vol.204
, pp. 805-817
-
-
Nylen, S.1
Maurya, R.2
Eidsmo, L.3
Manandhar, K.D.4
Sundar, S.5
Sacks, D.6
-
63
-
-
84893737751
-
IFNgamma/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children
-
Jagannathan P, Eccles-James I, Bowen K, Nankya F, Auma A, Wamala S, et al. IFNgamma/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children. PLoS Pathog (2014) 10:e1003864. doi:10.1371/journal.ppat.1003864
-
(2014)
PLoS Pathog
, vol.10
-
-
Jagannathan, P.1
Eccles-James, I.2
Bowen, K.3
Nankya, F.4
Auma, A.5
Wamala, S.6
-
64
-
-
84901376660
-
Exposure-dependent control of malaria-induced inflammation in children
-
Portugal S, Moebius J, Skinner J, Doumbo S, Doumtabe D, Kone Y, et al. Exposure-dependent control of malaria-induced inflammation in children. PLoS Pathog (2014) 10:e1004079. doi:10.1371/journal.ppat.1004079
-
(2014)
PLoS Pathog
, vol.10
-
-
Portugal, S.1
Moebius, J.2
Skinner, J.3
Doumbo, S.4
Doumtabe, D.5
Kone, Y.6
-
65
-
-
80052422191
-
IL-10 neutralization promotes parasite clearance in splenic aspirate cells from patients with visceral leishmaniasis
-
Gautam S, Kumar R, Maurya R, Nylen S, Ansari N, Rai M, et al. IL-10 neutralization promotes parasite clearance in splenic aspirate cells from patients with visceral leishmaniasis. J Infect Dis (2011) 204:1134-7. doi:10.1093/infdis/jir461
-
(2011)
J Infect Dis
, vol.204
, pp. 1134-1137
-
-
Gautam, S.1
Kumar, R.2
Maurya, R.3
Nylen, S.4
Ansari, N.5
Rai, M.6
-
66
-
-
19944432324
-
IFN-gamma and IL-10 mediate parasite-specific immune responses of cord blood cells induced by pregnancy-associated Plasmodium falciparum malaria
-
Brustoski K, Moller U, Kramer M, Petelski A, Brenner S, Palmer DR, et al. IFN-gamma and IL-10 mediate parasite-specific immune responses of cord blood cells induced by pregnancy-associated Plasmodium falciparum malaria. J Immunol (2005) 174:1738-45. doi:10.4049/jimmunol.174.3.1738
-
(2005)
J Immunol
, vol.174
, pp. 1738-1745
-
-
Brustoski, K.1
Moller, U.2
Kramer, M.3
Petelski, A.4
Brenner, S.5
Palmer, D.R.6
-
67
-
-
66349085903
-
Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria
-
Walther M, Jeffries D, Finney OC, Njie M, Ebonyi A, Deininger S, et al. Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria. PLoS Pathog (2009) 5:e1000364. doi:10.1371/journal.ppat.1000364
-
(2009)
PLoS Pathog
, vol.5
-
-
Walther, M.1
Jeffries, D.2
Finney, O.C.3
Njie, M.4
Ebonyi, A.5
Deininger, S.6
-
69
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell (1993) 75:263-74. doi:10.1016/0092-8674(93)80068-P
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
70
-
-
12944310982
-
IL-10-producing T cells suppress immune responses in anergic tuberculosis patients
-
Boussiotis VA, Tsai EY, Yunis EJ, Thim S, Delgado JC, Dascher CC, et al. IL-10-producing T cells suppress immune responses in anergic tuberculosis patients. J Clin Invest (2000) 105:1317-25. doi:10.1172/JCI9918
-
(2000)
J Clin Invest
, vol.105
, pp. 1317-1325
-
-
Boussiotis, V.A.1
Tsai, E.Y.2
Yunis, E.J.3
Thim, S.4
Delgado, J.C.5
Dascher, C.C.6
-
71
-
-
0033152407
-
Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum
-
Plebanski M, Flanagan KL, Lee EA, Reece WH, Hart K, Gelder C, et al. Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum. Immunity (1999) 10:651-60. doi:10.1016/S1074-7613(00)80064-3
-
(1999)
Immunity
, vol.10
, pp. 651-660
-
-
Plebanski, M.1
Flanagan, K.L.2
Lee, E.A.3
Reece, W.H.4
Hart, K.5
Gelder, C.6
-
72
-
-
47249098958
-
Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections
-
Ha SJ, West EE, Araki K, Smith KA, Ahmed R. Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections. Immunol Rev (2008) 223:317-33. doi:10.1111/j.1600-065X.2008.00638.x
-
(2008)
Immunol Rev
, vol.223
, pp. 317-333
-
-
Ha, S.J.1
West, E.E.2
Araki, K.3
Smith, K.A.4
Ahmed, R.5
-
73
-
-
77957059176
-
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
-
Jin HT, Anderson AC, Tan WG, West EE, Ha SJ, Araki K, et al. Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proc Natl Acad Sci U S A (2010) 107:14733-8. doi:10.1073/pnas.1009731107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14733-14738
-
-
Jin, H.T.1
Anderson, A.C.2
Tan, W.G.3
West, E.E.4
Ha, S.J.5
Araki, K.6
-
74
-
-
77953395286
-
LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites
-
Camisaschi C, Casati C, Rini F, Perego M, De Filippo A, Triebel F, et al. LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites. J Immunol (2010) 184:6545-51. doi:10.4049/jimmunol.0903879
-
(2010)
J Immunol
, vol.184
, pp. 6545-6551
-
-
Camisaschi, C.1
Casati, C.2
Rini, F.3
Perego, M.4
De Filippo, A.5
Triebel, F.6
-
75
-
-
0037152173
-
Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression
-
Sing A, Rost D, Tvardovskaia N, Roggenkamp A, Wiedemann A, Kirschning CJ, et al. Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression. J Exp Med (2002) 196:1017-24. doi:10.1084/jem.20020908
-
(2002)
J Exp Med
, vol.196
, pp. 1017-1024
-
-
Sing, A.1
Rost, D.2
Tvardovskaia, N.3
Roggenkamp, A.4
Wiedemann, A.5
Kirschning, C.J.6
-
76
-
-
79953048089
-
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
-
Ouyang W, Rutz S, Crellin NK, Valdez PA, Hymowitz SG. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol (2011) 29:71-109. doi:10.1146/annurev-immunol-031210-101312
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 71-109
-
-
Ouyang, W.1
Rutz, S.2
Crellin, N.K.3
Valdez, P.A.4
Hymowitz, S.G.5
-
77
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
-
Awasthi A, Carrier Y, Peron JP, Bettelli E, Kamanaka M, Flavell RA, et al. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat Immunol (2007) 8:1380-9. doi:10.1038/ni1541
-
(2007)
Nat Immunol
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
Carrier, Y.2
Peron, J.P.3
Bettelli, E.4
Kamanaka, M.5
Flavell, R.A.6
-
78
-
-
36248970702
-
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
-
Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, et al. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat Immunol (2007) 8:1372-9. doi:10.1038/ni1540
-
(2007)
Nat Immunol
, vol.8
, pp. 1372-1379
-
-
Fitzgerald, D.C.1
Zhang, G.X.2
El-Behi, M.3
Fonseca-Kelly, Z.4
Li, H.5
Yu, S.6
-
79
-
-
73149111975
-
Interleukin 27 adouble-edgeds word for offense and defense
-
Yoshida H, Nakaya M, Miyazaki Y. Interleukin 27: a double-edged sword for offense and defense. J Leukoc Biol (2009) 86:1295-303. doi:10.1189/jlb.0609445
-
(2009)
J Leukoc Biol
, vol.86
, pp. 1295-1303
-
-
Yoshida, H.1
Nakaya, M.2
Miyazaki, Y.3
-
80
-
-
69249083836
-
Cutting edge: IL-27induces the transcription factor c- Maf cytokine IL-21 and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
-
Pot C, Jin H, Awasthi A, Liu SM, Lai CY, Madan R, et al. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J Immunol (2009) 183:797-801. doi:10.4049/jimmunol.0901233
-
(2009)
J Immunol
, vol.183
, pp. 797-801
-
-
Pot, C.1
Jin, H.2
Awasthi, A.3
Liu, S.M.4
Lai, C.Y.5
Madan, R.6
-
81
-
-
64849083153
-
IL-21 mediates suppressive effects via its induction of IL-10
-
Spolski R, Kim HP, Zhu W, Levy DE, Leonard WJ. IL-21 mediates suppressive effects via its induction of IL-10. J Immunol (2009) 182:2859-67. doi:10.4049/jimmunol.0802978
-
(2009)
J Immunol
, vol.182
, pp. 2859-2867
-
-
Spolski, R.1
Kim, H.P.2
Zhu, W.3
Levy, D.E.4
Leonard, W.J.5
-
82
-
-
10744222574
-
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
-
Pflanz S, Hibbert L, Mattson J, Rosales R, Vaisberg E, Bazan JF, et al. WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J Immunol (2004) 172:2225-31. doi:10.4049/jimmunol.172.4.2225
-
(2004)
J Immunol
, vol.172
, pp. 2225-2231
-
-
Pflanz, S.1
Hibbert, L.2
Mattson, J.3
Rosales, R.4
Vaisberg, E.5
Bazan, J.F.6
-
83
-
-
18444385868
-
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells
-
Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. Immunity (2002) 16:779-90. doi:10.1016/S1074-7613(02)00324-2
-
(2002)
Immunity
, vol.16
, pp. 779-790
-
-
Pflanz, S.1
Timans, J.C.2
Cheung, J.3
Rosales, R.4
Kanzler, H.5
Gilbert, J.6
-
84
-
-
24744435772
-
Directing transition from innate to acquired immunity: defininga role for IL-6
-
Jones SA. Directing transition from innate to acquired immunity: defining a role for IL-6. J Immunol (2005) 175:3463-8. doi:10.4049/jimmunol.175.6.3463
-
(2005)
J Immunol
, vol.175
, pp. 3463-3468
-
-
Jones, S.A.1
-
86
-
-
77955903212
-
The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27
-
Apetoh L, Quintana FJ, Pot C, Joller N, Xiao S, Kumar D, et al. The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. Nat Immunol (2010) 11:854-61. doi:10.1038/ni.1912
-
(2010)
Nat Immunol
, vol.11
, pp. 854-861
-
-
Apetoh, L.1
Quintana, F.J.2
Pot, C.3
Joller, N.4
Xiao, S.5
Kumar, D.6
-
87
-
-
73249149628
-
c-Maf regulates IL-10 expression during Th17 polarization
-
Xu J, Yang Y, Qiu G, Lal G, Wu Z, Levy DE, et al. c-Maf regulates IL-10 expression during Th17 polarization. J Immunol (2009) 182:6226-36. doi:10.4049/jimmunol.0900123
-
(2009)
J Immunol
, vol.182
, pp. 6226-6236
-
-
Xu, J.1
Yang, Y.2
Qiu, G.3
Lal, G.4
Wu, Z.5
Levy, D.E.6
-
88
-
-
84862135028
-
Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells
-
Carrier Y, Whitters MJ, Miyashiro JS, LaBranche TP, Ramon HE, Benoit SE, et al. Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells. Eur J Immunol (2012) 42:1393-404. doi:10.1002/eji.201142162
-
(2012)
Eur J Immunol
, vol.42
, pp. 1393-1404
-
-
Carrier, Y.1
Whitters, M.J.2
Miyashiro, J.S.3
LaBranche, T.P.4
Ramon, H.E.5
Benoit, S.E.6
-
89
-
-
78449300568
-
A role for IL-27p28 as an antagonist of gp130-mediated signaling
-
Stumhofer JS, Tait ED, Quinn WJ III, Hosken N, Spudy B, Goenka R, et al. A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol (2010) 11:1119-26. doi:10.1038/ni.1957
-
(2010)
Nat Immunol
, vol.11
, pp. 1119-1126
-
-
Stumhofer, J.S.1
Tait, E.D.2
Quinn III, W.J.3
Hosken, N.4
Spudy, B.5
Goenka, R.6
-
90
-
-
77956899787
-
Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection
-
Findlay EG, Greig R, Stumhofer JS, Hafalla JC, de Souza JB, Saris CJ, et al. Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. J Immunol (2010) 185:2482-92. doi:10.4049/jimmunol.0904019
-
(2010)
J Immunol
, vol.185
, pp. 2482-2492
-
-
Findlay, E.G.1
Greig, R.2
Stumhofer, J.S.3
Hafalla, J.C.4
de Souza, J.B.5
Saris, C.J.6
-
91
-
-
70449732757
-
IL-27 regulates IL-10 and IL-17 from CD4+ cells in nonhealing Leishmania major infection
-
Anderson CF, Stumhofer JS, Hunter CA, Sacks D. IL-27 regulates IL-10 and IL-17 from CD4+ cells in nonhealing Leishmania major infection. J Immunol (2009) 183:4619-27. doi:10.4049/jimmunol.0804024
-
(2009)
J Immunol
, vol.183
, pp. 4619-4627
-
-
Anderson, C.F.1
Stumhofer, J.S.2
Hunter, C.A.3
Sacks, D.4
-
92
-
-
79955000536
-
IL-27 and IL-21 are associated with T cell IL-10 responses in human visceral leishmaniasis
-
Ansari NA, Kumar R, Gautam S, Nylen S, Singh OP, Sundar S, et al. IL-27 and IL-21 are associated with T cell IL-10 responses in human visceral leishmaniasis. J Immunol (2011) 186:3977-85. doi:10.4049/jimmunol.1003588
-
(2011)
J Immunol
, vol.186
, pp. 3977-3985
-
-
Ansari, N.A.1
Kumar, R.2
Gautam, S.3
Nylen, S.4
Singh, O.P.5
Sundar, S.6
-
93
-
-
79952955744
-
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
-
Cretney E, Xin A, Shi W, Minnich M, Masson F, Miasari M, et al. The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat Immunol (2011) 12:304-11. doi:10.1038/ni.2006
-
(2011)
Nat Immunol
, vol.12
, pp. 304-311
-
-
Cretney, E.1
Xin, A.2
Shi, W.3
Minnich, M.4
Masson, F.5
Miasari, M.6
-
94
-
-
84876436991
-
Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+ T cells
-
Iwasaki Y, Fujio K, Okamura T, Yanai A, Sumitomo S, Shoda H, et al. Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+ T cells. Eur J Immunol (2013) 43:1063-73. doi:10.1002/eji.201242942
-
(2013)
Eur J Immunol
, vol.43
, pp. 1063-1073
-
-
Iwasaki, Y.1
Fujio, K.2
Okamura, T.3
Yanai, A.4
Sumitomo, S.5
Shoda, H.6
-
95
-
-
84906534462
-
Role of Blimp-1 in programing Th effector cells into IL-10 producers
-
Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi MF, Ahlers J, et al. Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med (2014) 211:1807-19. doi:10.1084/jem.20131548
-
(2014)
J Exp Med
, vol.211
, pp. 1807-1819
-
-
Neumann, C.1
Heinrich, F.2
Neumann, K.3
Junghans, V.4
Mashreghi, M.F.5
Ahlers, J.6
-
96
-
-
69549124480
-
CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2
-
Okamura T, Fujio K, Shibuya M, Sumitomo S, Shoda H, Sakaguchi S, et al. CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2. Proc Natl Acad Sci U S A (2009) 106:13974-9. doi:10.1073/pnas.0906872106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13974-13979
-
-
Okamura, T.1
Fujio, K.2
Shibuya, M.3
Sumitomo, S.4
Shoda, H.5
Sakaguchi, S.6
-
97
-
-
76249101454
-
Cutting edge: plasmacytoid dendritic cells induce IL-10productioninTcellsviathedelta-like- 4/Notchaxis
-
Kassner N, Krueger M, Yagita H, Dzionek A, Hutloff A, Kroczek R, et al. Cutting edge: plasmacytoid dendritic cells induce IL-10 production in T cells via the delta-like-4/Notch axis. J Immunol (2010) 184:550-4. doi:10.4049/jimmunol.0903152
-
(2010)
J Immunol
, vol.184
, pp. 550-554
-
-
Kassner, N.1
Krueger, M.2
Yagita, H.3
Dzionek, A.4
Hutloff, A.5
Kroczek, R.6
-
98
-
-
0000520727
-
Virus interference I The interferon
-
Isaacs A, Lindenmann J. Virus interference. I. The interferon. Proc R Soc Lond B Biol Sci (1957) 147:258-67. doi:10.1098/rspb.1957.0049
-
(1957)
Proc R Soc Lond B Biol Sci
, vol.147
, pp. 258-267
-
-
Isaacs, A.1
Lindenmann, J.2
-
100
-
-
58149277739
-
Type I IFNs play a role in early resistance, but subsequent susceptibility, to the African trypanosomes
-
Lopez R, Demick KP, Mansfield JM, Paulnock DM. Type I IFNs play a role in early resistance, but subsequent susceptibility, to the African trypanosomes. J Immunol (2008) 181:4908-17. doi:10.4049/jimmunol.181.7.4908
-
(2008)
J Immunol
, vol.181
, pp. 4908-4917
-
-
Lopez, R.1
Demick, K.P.2
Mansfield, J.M.3
Paulnock, D.M.4
-
101
-
-
79955605871
-
Type I interferons increase host susceptibility to Trypanosoma cruzi infection
-
Chessler AD, Caradonna KL, Da'dara A, Burleigh BA. Type I interferons increase host susceptibility to Trypanosoma cruzi infection. Infect Immun (2011) 79:2112-9. doi:10.1128/IAI.01176-10
-
(2011)
Infect Immun
, vol.79
, pp. 2112-2119
-
-
Chessler, A.D.1
Caradonna, K.L.2
Da'dara, A.3
Burleigh, B.A.4
-
102
-
-
84891874162
-
Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection
-
Liehl P, Zuzarte-Luis V, Chan J, Zillinger T, Baptista F, Carapau D, et al. Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection. Nat Med (2014) 20:47-53. doi:10.1038/nm.3424
-
(2014)
Nat Med
, vol.20
, pp. 47-53
-
-
Liehl, P.1
Zuzarte-Luis, V.2
Chan, J.3
Zillinger, T.4
Baptista, F.5
Carapau, D.6
-
103
-
-
80052174883
-
Type I interferons suppress CD4(+) T-cell-dependent parasite control during blood-stage Plasmodium infection
-
Haque A, Best SE, Ammerdorffer A, Desbarrieres L, de Oca MM, Amante FH, et al. Type I interferons suppress CD4(+) T-cell-dependent parasite control during blood-stage Plasmodium infection. Eur J Immunol (2011) 41:2688-98. doi:10.1002/eji.201141539
-
(2011)
Eur J Immunol
, vol.41
, pp. 2688-2698
-
-
Haque, A.1
Best, S.E.2
Ammerdorffer, A.3
Desbarrieres, L.4
de Oca, M.M.5
Amante, F.H.6
-
104
-
-
80051880722
-
Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome
-
Sharma S, DeOliveira RB, Kalantari P, Parroche P, Goutagny N, Jiang Z, et al. Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome. Immunity (2011) 35:194-207. doi:10.1016/j.immuni.2011.05.016
-
(2011)
Immunity
, vol.35
, pp. 194-207
-
-
Sharma, S.1
DeOliveira, R.B.2
Kalantari, P.3
Parroche, P.4
Goutagny, N.5
Jiang, Z.6
-
105
-
-
84902182316
-
Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity
-
Haque A, Best SE, Montes de Oca M, James KR, Ammerdorffer A, Edwards CL, et al. Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity. J Clin Invest (2014) 124:2483-96. doi:10.1172/JCI70698
-
(2014)
J Clin Invest
, vol.124
, pp. 2483-2496
-
-
Haque, A.1
Best, S.E.2
Montes de Oca, M.3
James, K.R.4
Ammerdorffer, A.5
Edwards, C.L.6
-
106
-
-
84888133819
-
Regulation of immunopathogenesis during Plasmodium and Toxoplasma infections: more parallels than distinctions?
-
Butler NS, Harris TH, Blader IJ. Regulation of immunopathogenesis during Plasmodium and Toxoplasma infections: more parallels than distinctions? Trends Parasitol (2013) 29:593-602. doi:10.1016/j.pt.2013.10.002
-
(2013)
Trends Parasitol
, vol.29
, pp. 593-602
-
-
Butler, N.S.1
Harris, T.H.2
Blader, I.J.3
-
107
-
-
0027440279
-
Profiles of cytokine production in relation with susceptibility to cerebral malaria
-
de Kossodo S, Grau GE. Profiles of cytokine production in relation with susceptibility to cerebral malaria. J Immunol (1993) 151:4811-20.
-
(1993)
J Immunol
, vol.151
, pp. 4811-4820
-
-
de Kossodo, S.1
Grau, G.E.2
-
108
-
-
0035123650
-
Murine ileitis after intracellular parasite infection is controlled by TGF-beta-producing intraepithelial lymphocytes
-
Buzoni-Gatel D, Debbabi H, Mennechet FJ, Martin V, Lepage AC, Schwartzman JD, et al. Murine ileitis after intracellular parasite infection is controlled by TGF-beta-producing intraepithelial lymphocytes. Gastroenterology (2001) 120:914-24. doi:10.1053/gast.2001.22432a
-
(2001)
Gastroenterology
, vol.120
, pp. 914-924
-
-
Buzoni-Gatel, D.1
Debbabi, H.2
Mennechet, F.J.3
Martin, V.4
Lepage, A.C.5
Schwartzman, J.D.6
-
109
-
-
48449086316
-
TGF-beta: a mastero fall T cell trades
-
Li MO, Flavell RA. TGF-beta: a master of all T cell trades. Cell (2008) 134:392-404. doi:10.1016/j.cell.2008.07.025
-
(2008)
Cell
, vol.134
, pp. 392-404
-
-
Li, M.O.1
Flavell, R.A.2
-
110
-
-
0036141930
-
Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity
-
Aliberti J, Hieny S, Reis e Sousa C, Serhan CN, Sher A. Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. Nat Immunol (2002) 3:76-82. doi:10.1038/ni745
-
(2002)
Nat Immunol
, vol.3
, pp. 76-82
-
-
Aliberti, J.1
Hieny, S.2
Reis e Sousa, C.3
Serhan, C.N.4
Sher, A.5
-
111
-
-
0037020861
-
Parasite-induced lipoxin A4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection
-
Aliberti J, Serhan C, Sher A. Parasite-induced lipoxin A4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection. J Exp Med (2002) 196:1253-62. doi:10.1084/jem.20021183
-
(2002)
J Exp Med
, vol.196
, pp. 1253-1262
-
-
Aliberti, J.1
Serhan, C.2
Sher, A.3
-
112
-
-
84885462754
-
CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection
-
Kugler DG, Mittelstadt PR, Ashwell JD, Sher A, Jankovic D. CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection. J Exp Med (2013) 210:1919-27. doi:10.1084/jem.20122300
-
(2013)
J Exp Med
, vol.210
, pp. 1919-1927
-
-
Kugler, D.G.1
Mittelstadt, P.R.2
Ashwell, J.D.3
Sher, A.4
Jankovic, D.5
-
113
-
-
0029959459
-
In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12 IFN-gamma and TNF-alpha
-
Gazzinelli RT, Wysocka M, Hieny S, Scharton-Kersten T, Cheever A, Kuhn R, et al. In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha. J Immunol (1996) 157:798-805.
-
(1996)
J Immunol
, vol.157
, pp. 798-805
-
-
Gazzinelli, R.T.1
Wysocka, M.2
Hieny, S.3
Scharton-Kersten, T.4
Cheever, A.5
Kuhn, R.6
-
114
-
-
78649848029
-
Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria
-
Amante FH, Haque A, Stanley AC, Rivera Fde L, Randall LM, Wilson YA, et al. Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria. J Immunol (2010) 185:3632-42. doi:10.4049/jimmunol.1000944
-
(2010)
J Immunol
, vol.185
, pp. 3632-3642
-
-
Amante, F.H.1
Haque, A.2
Stanley, A.C.3
Rivera Fde, L.4
Randall, L.M.5
Wilson, Y.A.6
-
115
-
-
28244482371
-
Anti-CD25 antibody enhancement of vaccine-induced immunogenicity: increased durable cellular immunity with reduced immunodominance
-
Moore AC, Gallimore A, Draper SJ, Watkins KR, Gilbert SC, Hill AV. Anti-CD25 antibody enhancement of vaccine-induced immunogenicity: increased durable cellular immunity with reduced immunodominance. J Immunol (2005) 175:7264-73. doi:10.4049/jimmunol.175.11.7264
-
(2005)
J Immunol
, vol.175
, pp. 7264-7273
-
-
Moore, A.C.1
Gallimore, A.2
Draper, S.J.3
Watkins, K.R.4
Gilbert, S.C.5
Hill, A.V.6
-
116
-
-
23444440849
-
IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection
-
Stober CB, Lange UG, Roberts MT, Alcami A, Blackwell JM. IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection. J Immunol (2005) 175:2517-24. doi:10.4049/jimmunol.175.4.2517
-
(2005)
J Immunol
, vol.175
, pp. 2517-2524
-
-
Stober, C.B.1
Lange, U.G.2
Roberts, M.T.3
Alcami, A.4
Blackwell, J.M.5
-
117
-
-
33744907022
-
Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation
-
Shaw MH, Freeman GJ, Scott MF, Fox BA, Bzik DJ, Belkaid Y, et al. Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation. J Immunol (2006) 176:7263-71. doi:10.4049/jimmunol.176.12.7263
-
(2006)
J Immunol
, vol.176
, pp. 7263-7271
-
-
Shaw, M.H.1
Freeman, G.J.2
Scott, M.F.3
Fox, B.A.4
Bzik, D.J.5
Belkaid, Y.6
|