CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection

Journal of Experimental Medicine

Volumn 210, Issue 10, 2013, Pages 1919-1927

  Kugler, David G ^a,c   Mittelstadt, Paul R ^b   Ashwell, Jonathan D ^a   Sher, Alan ^a   Jankovic, Dragana ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CORTICOSTERONE; CREATINE KINASE; GAMMA INTERFERON; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 27; TUMOR NECROSIS FACTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FUNCTION; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HORMONE RESPONSE; HOST RESISTANCE; HYPERACTIVITY; IMMUNOMODULATION; IMMUNOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MORTALITY; MOUSE; NONHUMAN; PARASITE LOAD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL; T CELL DEPLETION; TARGET CELL; TH1 CELL; TOXOPLASMA GONDII; TOXOPLASMOSIS; WEIGHT REDUCTION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; GLUCOCORTICOIDS; MICE; MICE, KNOCKOUT; RECEPTORS, GLUCOCORTICOID; SIGNAL TRANSDUCTION; TH1 CELLS; TOXOPLASMA; TOXOPLASMOSIS;

EID: 84885462754     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122300     Document Type: Article

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