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Volumn 10, Issue 1, 2014, Pages

IFNγ/IL-10 Co-producing Cells Dominate the CD4 Response to Malaria in Highly Exposed Children

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IFNG PROTEIN, HUMAN; IL10 PROTEIN, HUMAN; INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA;

EID: 84893737751     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003864     Document Type: Article
Times cited : (109)

References (94)
  • 2
    • 33644871833 scopus 로고    scopus 로고
    • Immune effector mechanisms in malaria
    • Marsh K, Kinyanjui S, (2006) Immune effector mechanisms in malaria. Parasite Immunol 28: 51-60.
    • (2006) Parasite Immunol , vol.28 , pp. 51-60
    • Marsh, K.1    Kinyanjui, S.2
  • 3
    • 84878883055 scopus 로고    scopus 로고
    • An intensive longitudinal cohort study of Malian children and adults reveals no evidence of acquired immunity to Plasmodium falciparum infection
    • Tran TM, Li S, Doumbo S, Doumtabe D, Huang CY, et al. (2013) An intensive longitudinal cohort study of Malian children and adults reveals no evidence of acquired immunity to Plasmodium falciparum infection. Clin Infect Dis 57: 40-47.
    • (2013) Clin Infect Dis , vol.57 , pp. 40-47
    • Tran, T.M.1    Li, S.2    Doumbo, S.3    Doumtabe, D.4    Huang, C.Y.5
  • 4
    • 0026728163 scopus 로고
    • Is immunity to malaria really short-lived
    • Deloron P, Chougnet C, (1992) Is immunity to malaria really short-lived? Parasitol Today 8: 375-378.
    • (1992) Parasitol Today , vol.8 , pp. 375-378
    • Deloron, P.1    Chougnet, C.2
  • 6
    • 77949517352 scopus 로고    scopus 로고
    • Contrasting population structures of the genes encoding ten leading vaccine-candidate antigens of the human malaria parasite, Plasmodium falciparum
    • Barry AE, Schultz L, Buckee CO, Reeder JC, (2009) Contrasting population structures of the genes encoding ten leading vaccine-candidate antigens of the human malaria parasite, Plasmodium falciparum. PLoS ONE 4: e8497.
    • (2009) PLoS ONE , vol.4
    • Barry, A.E.1    Schultz, L.2    Buckee, C.O.3    Reeder, J.C.4
  • 7
    • 0033166040 scopus 로고    scopus 로고
    • T-cell function in newborn mice and humans
    • Adkins B, (1999) T-cell function in newborn mice and humans. Immunol Today 20: 330-335.
    • (1999) Immunol Today , vol.20 , pp. 330-335
    • Adkins, B.1
  • 8
    • 0021054996 scopus 로고
    • Specific cell-mediated immunity and the natural history of congenital infection with cytomegalovirus
    • Pass RF, Stagno S, Britt WJ, Alford CA, (1983) Specific cell-mediated immunity and the natural history of congenital infection with cytomegalovirus. J Infect Dis 148: 953-961.
    • (1983) J Infect Dis , vol.148 , pp. 953-961
    • Pass, R.F.1    Stagno, S.2    Britt, W.J.3    Alford, C.A.4
  • 10
    • 0038481193 scopus 로고    scopus 로고
    • Functionally mature virus-specific CD8(+) T memory cells in congenitally infected newborns: proof of principle for neonatal vaccination
    • Holt PG, (2003) Functionally mature virus-specific CD8(+) T memory cells in congenitally infected newborns: proof of principle for neonatal vaccination? J Clin Invest 111: 1645-1647.
    • (2003) J Clin Invest , vol.111 , pp. 1645-1647
    • Holt, P.G.1
  • 11
    • 0025281308 scopus 로고
    • Basis and implications of selectively diminished cytokine production in neonatal susceptibility to infection
    • Wilson CB, Lewis DB, (1990) Basis and implications of selectively diminished cytokine production in neonatal susceptibility to infection. Rev Infect Dis 12 (Suppl 4) (): S410-420.
    • (1990) Rev Infect Dis , vol.12 , Issue.SUPPL. 4
    • Wilson, C.B.1    Lewis, D.B.2
  • 13
    • 0022648628 scopus 로고
    • Antigen-specific immunosuppression in human malaria due to Plasmodium falciparum
    • Ho M, Webster HK, Looareesuwan S, Supanaranond W, Phillips RE, et al. (1986) Antigen-specific immunosuppression in human malaria due to Plasmodium falciparum. J Infect Dis 153: 763-771.
    • (1986) J Infect Dis , vol.153 , pp. 763-771
    • Ho, M.1    Webster, H.K.2    Looareesuwan, S.3    Supanaranond, W.4    Phillips, R.E.5
  • 14
    • 0033152407 scopus 로고    scopus 로고
    • Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum
    • Plebanski M, Flanagan KL, Lee EA, Reece WH, Hart K, et al. (1999) Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum. Immunity 10: 651-660.
    • (1999) Immunity , vol.10 , pp. 651-660
    • Plebanski, M.1    Flanagan, K.L.2    Lee, E.A.3    Reece, W.H.4    Hart, K.5
  • 15
    • 24944466472 scopus 로고    scopus 로고
    • Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection
    • Walther M, Tongren JE, Andrews L, Korbel D, King E, et al. (2005) Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity 23: 287-296.
    • (2005) Immunity , vol.23 , pp. 287-296
    • Walther, M.1    Tongren, J.E.2    Andrews, L.3    Korbel, D.4    King, E.5
  • 16
    • 35748960534 scopus 로고    scopus 로고
    • The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum
    • Bejon P, Mwacharo J, Kai O, Todryk S, Keating S, et al. (2007) The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum. J Immunol 179: 4193-4201.
    • (2007) J Immunol , vol.179 , pp. 4193-4201
    • Bejon, P.1    Mwacharo, J.2    Kai, O.3    Todryk, S.4    Keating, S.5
  • 17
    • 84855911057 scopus 로고    scopus 로고
    • Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection
    • Butler NS, Moebius J, Pewe LL, Traore B, Doumbo OK, et al. (2012) Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection. Nat Immunol 13: 188-195.
    • (2012) Nat Immunol , vol.13 , pp. 188-195
    • Butler, N.S.1    Moebius, J.2    Pewe, L.L.3    Traore, B.4    Doumbo, O.K.5
  • 18
    • 84856567798 scopus 로고    scopus 로고
    • IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection
    • Freitas do Rosario AP, Lamb T, Spence P, Stephens R, Lang A, et al. (2012) IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. J Immunol 188: 1178-1190.
    • (2012) J Immunol , vol.188 , pp. 1178-1190
    • Freitas do Rosario, A.P.1    Lamb, T.2    Spence, P.3    Stephens, R.4    Lang, A.5
  • 19
    • 84861680926 scopus 로고    scopus 로고
    • T cell-derived IL-10 and its impact on the regulation of host responses during malaria
    • Freitas do Rosario AP, Langhorne J, (2012) T cell-derived IL-10 and its impact on the regulation of host responses during malaria. Int J Parasitol 42: 549-555.
    • (2012) Int J Parasitol , vol.42 , pp. 549-555
    • Freitas do Rosario, A.P.1    Langhorne, J.2
  • 20
    • 84872804186 scopus 로고    scopus 로고
    • Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda
    • Jagannathan P, Muhindo MK, Kakuru A, Arinaitwe E, Greenhouse B, et al. (2012) Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda. Malar J 11: 435.
    • (2012) Malar J , vol.11 , pp. 435
    • Jagannathan, P.1    Muhindo, M.K.2    Kakuru, A.3    Arinaitwe, E.4    Greenhouse, B.5
  • 22
    • 81855195364 scopus 로고    scopus 로고
    • Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study
    • Trape JF, Tall A, Diagne N, Ndiath O, Ly AB, et al. (2011) Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study. Lancet Infectious Diseases 11: 925-932.
    • (2011) Lancet Infectious Diseases , vol.11 , pp. 925-932
    • Trape, J.F.1    Tall, A.2    Diagne, N.3    Ndiath, O.4    Ly, A.B.5
  • 23
    • 0023483210 scopus 로고
    • Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites
    • Schofield L, Villaquiran J, Ferreira A, Schellekens H, Nussenzweig R, et al. (1987) Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites. Nature 330: 664-666.
    • (1987) Nature , vol.330 , pp. 664-666
    • Schofield, L.1    Villaquiran, J.2    Ferreira, A.3    Schellekens, H.4    Nussenzweig, R.5
  • 24
    • 0024954612 scopus 로고
    • Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria
    • Romero P, Maryanski JL, Corradin G, Nussenzweig RS, Nussenzweig V, et al. (1989) Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature 341: 323-326.
    • (1989) Nature , vol.341 , pp. 323-326
    • Romero, P.1    Maryanski, J.L.2    Corradin, G.3    Nussenzweig, R.S.4    Nussenzweig, V.5
  • 25
    • 0027361805 scopus 로고
    • The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria
    • Rodrigues M, Nussenzweig RS, Zavala F, (1993) The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria. Immunology 80: 1-5.
    • (1993) Immunology , vol.80 , pp. 1-5
    • Rodrigues, M.1    Nussenzweig, R.S.2    Zavala, F.3
  • 26
    • 0031903091 scopus 로고    scopus 로고
    • Recombinant Sindbis viruses expressing a cytotoxic T-lymphocyte epitope of a malaria parasite or of influenza virus elicit protection against the corresponding pathogen in mice
    • Tsuji M, Bergmann CC, Takita-Sonoda Y, Murata K, Rodrigues EG, et al. (1998) Recombinant Sindbis viruses expressing a cytotoxic T-lymphocyte epitope of a malaria parasite or of influenza virus elicit protection against the corresponding pathogen in mice. J Virol 72: 6907-6910.
    • (1998) J Virol , vol.72 , pp. 6907-6910
    • Tsuji, M.1    Bergmann, C.C.2    Takita-Sonoda, Y.3    Murata, K.4    Rodrigues, E.G.5
  • 27
    • 23944469910 scopus 로고    scopus 로고
    • Malaria-specific transgenic CD4(+) T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance
    • Stephens R, Albano FR, Quin S, Pascal BJ, Harrison V, et al. (2005) Malaria-specific transgenic CD4(+) T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance. Blood 106: 1676-1684.
    • (2005) Blood , vol.106 , pp. 1676-1684
    • Stephens, R.1    Albano, F.R.2    Quin, S.3    Pascal, B.J.4    Harrison, V.5
  • 28
    • 52949138683 scopus 로고    scopus 로고
    • Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria
    • Schmidt NW, Podyminogin RL, Butler NS, Badovinac VP, Tucker BJ, et al. (2008) Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria. Proc Natl Acad Sci U S A 105: 14017-14022.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14017-14022
    • Schmidt, N.W.1    Podyminogin, R.L.2    Butler, N.S.3    Badovinac, V.P.4    Tucker, B.J.5
  • 29
    • 52049105157 scopus 로고    scopus 로고
    • Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response
    • Overstreet MG, Cockburn IA, Chen YC, Zavala F, (2008) Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response. Immunol Rev 225: 272-283.
    • (2008) Immunol Rev , vol.225 , pp. 272-283
    • Overstreet, M.G.1    Cockburn, I.A.2    Chen, Y.C.3    Zavala, F.4
  • 30
    • 79251485291 scopus 로고    scopus 로고
    • Effector memory Th1 CD4 T cells are maintained in a mouse model of chronic malaria
    • Stephens R, Langhorne J, (2010) Effector memory Th1 CD4 T cells are maintained in a mouse model of chronic malaria. PLoS Pathog 6: e1001208.
    • (2010) PLoS Pathog , vol.6
    • Stephens, R.1    Langhorne, J.2
  • 31
    • 0014202885 scopus 로고
    • Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei
    • Nussenzweig RS, Vanderberg J, Most H, Orton C, (1967) Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei. Nature 216: 160-162.
    • (1967) Nature , vol.216 , pp. 160-162
    • Nussenzweig, R.S.1    Vanderberg, J.2    Most, H.3    Orton, C.4
  • 32
    • 0015699215 scopus 로고
    • Immunization of man against sporozite-induced falciparum malaria
    • Clyde DF, Most H, McCarthy VC, Vanderberg JP, (1973) Immunization of man against sporozite-induced falciparum malaria. Am J Med Sci 266: 169-177.
    • (1973) Am J Med Sci , vol.266 , pp. 169-177
    • Clyde, D.F.1    Most, H.2    McCarthy, V.C.3    Vanderberg, J.P.4
  • 33
    • 0033693818 scopus 로고    scopus 로고
    • Malaria vaccines-targeting infected hepatocytes
    • Hoffman SL, Doolan DL, (2000) Malaria vaccines-targeting infected hepatocytes. Nat Med 6: 1218-1219.
    • (2000) Nat Med , vol.6 , pp. 1218-1219
    • Hoffman, S.L.1    Doolan, D.L.2
  • 34
    • 68049143479 scopus 로고    scopus 로고
    • Protection against a malaria challenge by sporozoite inoculation
    • Roestenberg M, McCall M, Hopman J, Wiersma J, Luty AJ, et al. (2009) Protection against a malaria challenge by sporozoite inoculation. N Engl J Med 361: 468-477.
    • (2009) N Engl J Med , vol.361 , pp. 468-477
    • Roestenberg, M.1    McCall, M.2    Hopman, J.3    Wiersma, J.4    Luty, A.J.5
  • 36
    • 79956358442 scopus 로고    scopus 로고
    • Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study
    • Roestenberg M, Teirlinck AC, McCall MB, Teelen K, Makamdop KN, et al. (2011) Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study. Lancet 377: 1770-1776.
    • (2011) Lancet , vol.377 , pp. 1770-1776
    • Roestenberg, M.1    Teirlinck, A.C.2    McCall, M.B.3    Teelen, K.4    Makamdop, K.N.5
  • 37
    • 11144353591 scopus 로고    scopus 로고
    • A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease
    • Reece WH, Pinder M, Gothard PK, Milligan P, Bojang K, et al. (2004) A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease. Nat Med 10: 406-410.
    • (2004) Nat Med , vol.10 , pp. 406-410
    • Reece, W.H.1    Pinder, M.2    Gothard, P.K.3    Milligan, P.4    Bojang, K.5
  • 38
    • 44349150336 scopus 로고    scopus 로고
    • Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans
    • Todryk SM, Bejon P, Mwangi T, Plebanski M, Urban B, et al. (2008) Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans. PLoS ONE 3: e2027.
    • (2008) PLoS ONE , vol.3
    • Todryk, S.M.1    Bejon, P.2    Mwangi, T.3    Plebanski, M.4    Urban, B.5
  • 39
    • 0035011161 scopus 로고    scopus 로고
    • Pre-erythrocytic immunity to Plasmodium falciparum: the case for an LSA-1 vaccine
    • Kurtis JD, Hollingdale MR, Luty AJ, Lanar DE, Krzych U, et al. (2001) Pre-erythrocytic immunity to Plasmodium falciparum: the case for an LSA-1 vaccine. Trends Parasitol 17: 219-223.
    • (2001) Trends Parasitol , vol.17 , pp. 219-223
    • Kurtis, J.D.1    Hollingdale, M.R.2    Luty, A.J.3    Lanar, D.E.4    Krzych, U.5
  • 40
    • 0024555887 scopus 로고
    • Human lymphocyte proliferative response to a sporozoite T cell epitope correlates with resistance to falciparum malaria
    • Hoffman SL, Oster CN, Mason C, Beier JC, Sherwood JA, et al. (1989) Human lymphocyte proliferative response to a sporozoite T cell epitope correlates with resistance to falciparum malaria. J Immunol 142: 1299-1303.
    • (1989) J Immunol , vol.142 , pp. 1299-1303
    • Hoffman, S.L.1    Oster, C.N.2    Mason, C.3    Beier, J.C.4    Sherwood, J.A.5
  • 41
    • 0032948127 scopus 로고    scopus 로고
    • Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children
    • Luty AJ, Lell B, Schmidt-Ott R, Lehman LG, Luckner D, et al. (1999) Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children. J Infect Dis 179: 980-988.
    • (1999) J Infect Dis , vol.179 , pp. 980-988
    • Luty, A.J.1    Lell, B.2    Schmidt-Ott, R.3    Lehman, L.G.4    Luckner, D.5
  • 42
    • 84878556137 scopus 로고    scopus 로고
    • Humoral and Cellular Immunity to Plasmodium falciparum Merozoite Surface Protein 1 and Protection From Infection With Blood-Stage Parasites
    • Moormann AM, Sumba PO, Chelimo K, Fang H, Tisch DJ, et al. (2013) Humoral and Cellular Immunity to Plasmodium falciparum Merozoite Surface Protein 1 and Protection From Infection With Blood-Stage Parasites. J Infect Dis 208: 149-158.
    • (2013) J Infect Dis , vol.208 , pp. 149-158
    • Moormann, A.M.1    Sumba, P.O.2    Chelimo, K.3    Fang, H.4    Tisch, D.J.5
  • 44
    • 71949112415 scopus 로고    scopus 로고
    • Early interferon-gamma response against Plasmodium falciparum correlates with interethnic differences in susceptibility to parasitemia between sympatric Fulani and Dogon in Mali
    • McCall MB, Hopman J, Daou M, Maiga B, Dara V, et al. (2010) Early interferon-gamma response against Plasmodium falciparum correlates with interethnic differences in susceptibility to parasitemia between sympatric Fulani and Dogon in Mali. J Infect Dis 201: 142-152.
    • (2010) J Infect Dis , vol.201 , pp. 142-152
    • McCall, M.B.1    Hopman, J.2    Daou, M.3    Maiga, B.4    Dara, V.5
  • 45
    • 65449158874 scopus 로고    scopus 로고
    • Analysis of immunity to febrile malaria in children that distinguishes immunity from lack of exposure
    • Bejon P, Warimwe G, Mackintosh CL, Mackinnon MJ, Kinyanjui SM, et al. (2009) Analysis of immunity to febrile malaria in children that distinguishes immunity from lack of exposure. Infect Immun 77: 1917-1923.
    • (2009) Infect Immun , vol.77 , pp. 1917-1923
    • Bejon, P.1    Warimwe, G.2    Mackintosh, C.L.3    Mackinnon, M.J.4    Kinyanjui, S.M.5
  • 46
    • 79957928865 scopus 로고    scopus 로고
    • Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemic
    • Greenhouse B, Ho B, Hubbard A, Njama-Meya D, Narum DL, et al. (2011) Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemic. J Infect Dis 204: 19-26.
    • (2011) J Infect Dis , vol.204 , pp. 19-26
    • Greenhouse, B.1    Ho, B.2    Hubbard, A.3    Njama-Meya, D.4    Narum, D.L.5
  • 48
    • 34250303350 scopus 로고    scopus 로고
    • Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
    • Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, et al. (2007) Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nature medicine 13: 843-850.
    • (2007) Nature Medicine , vol.13 , pp. 843-850
    • Darrah, P.A.1    Patel, D.T.2    De Luca, P.M.3    Lindsay, R.W.4    Davey, D.F.5
  • 49
    • 33847163271 scopus 로고    scopus 로고
    • CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
    • Anderson CF, Oukka M, Kuchroo VJ, Sacks D, (2007) CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med 204: 285-297.
    • (2007) J Exp Med , vol.204 , pp. 285-297
    • Anderson, C.F.1    Oukka, M.2    Kuchroo, V.J.3    Sacks, D.4
  • 50
    • 33847144180 scopus 로고    scopus 로고
    • Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
    • Jankovic D, Kullberg MC, Feng CG, Goldszmid RS, Collazo CM, et al. (2007) Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J Exp Med 204: 273-283.
    • (2007) J Exp Med , vol.204 , pp. 273-283
    • Jankovic, D.1    Kullberg, M.C.2    Feng, C.G.3    Goldszmid, R.S.4    Collazo, C.M.5
  • 51
    • 80053602298 scopus 로고    scopus 로고
    • Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01(E) and Protection against P falciparum Clinical Malaria
    • Olotu A, Moris P, Mwacharo J, Vekemans J, Kimani D, et al. (2011) Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01(E) and Protection against P falciparum Clinical Malaria. PLoS ONE 6: e25786.
    • (2011) PLoS ONE , vol.6
    • Olotu, A.1    Moris, P.2    Mwacharo, J.3    Vekemans, J.4    Kimani, D.5
  • 52
    • 66349085903 scopus 로고    scopus 로고
    • Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria
    • Walther M, Jeffries D, Finney OC, Njie M, Ebonyi A, et al. (2009) Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria. PLoS Pathog 5: e1000364.
    • (2009) PLoS Pathog , vol.5
    • Walther, M.1    Jeffries, D.2    Finney, O.C.3    Njie, M.4    Ebonyi, A.5
  • 53
    • 84864816607 scopus 로고    scopus 로고
    • Interleukin-10 (IL-10) polymorphisms are associated with IL-10 production and clinical malaria in young children
    • Zhang G, Manaca MN, McNamara-Smith M, Mayor A, Nhabomba A, et al. (2012) Interleukin-10 (IL-10) polymorphisms are associated with IL-10 production and clinical malaria in young children. Infect Immun 80: 2316-2322.
    • (2012) Infect Immun , vol.80 , pp. 2316-2322
    • Zhang, G.1    Manaca, M.N.2    McNamara-Smith, M.3    Mayor, A.4    Nhabomba, A.5
  • 54
    • 80055087402 scopus 로고    scopus 로고
    • Live Attenuated Malaria Vaccine Designed to Protect through Hepatic CD8+ T Cell Immunity
    • Epstein JE, Tewari K, Lyke KE, Sim BK, Billingsley PF,et al. (2011) Live Attenuated Malaria Vaccine Designed to Protect through Hepatic CD8+ T Cell Immunity. Science.
    • (2011) Science
    • Epstein, J.E.1    Tewari, K.2    Lyke, K.E.3    Sim, B.K.4    Billingsley, P.F.5
  • 55
    • 80053602298 scopus 로고    scopus 로고
    • Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria
    • Olotu A, Moris P, Mwacharo J, Vekemans J, Kimani D, et al. (2011) Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria. PLoS ONE 6: e25786.
    • (2011) PLoS ONE , vol.6
    • Olotu, A.1    Moris, P.2    Mwacharo, J.3    Vekemans, J.4    Kimani, D.5
  • 56
    • 79957713226 scopus 로고    scopus 로고
    • The Th1 life cycle: molecular control of IFN-gamma to IL-10 switching
    • Cope A, Le Friec G, Cardone J, Kemper C, (2011) The Th1 life cycle: molecular control of IFN-gamma to IL-10 switching. Trends in Immunology 32: 278-286.
    • (2011) Trends in Immunology , vol.32 , pp. 278-286
    • Cope, A.1    Le Friec, G.2    Cardone, J.3    Kemper, C.4
  • 57
    • 34249678457 scopus 로고    scopus 로고
    • T(H)1 cells control themselves by producing interleukin-10
    • O'Garra A, Vieira P, (2007) T(H)1 cells control themselves by producing interleukin-10. Nature reviews Immunology 7: 425-428.
    • (2007) Nature Reviews Immunology , vol.7 , pp. 425-428
    • O'Garra, A.1    Vieira, P.2
  • 61
    • 84884214616 scopus 로고    scopus 로고
    • Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria
    • Pinzon-Charry A, Woodberry T, Kienzle V, McPhun V, Minigo G, et al. (2013) Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria. J Exp Med 210: 1635-1646.
    • (2013) J Exp Med , vol.210 , pp. 1635-1646
    • Pinzon-Charry, A.1    Woodberry, T.2    Kienzle, V.3    McPhun, V.4    Minigo, G.5
  • 62
    • 0344430170 scopus 로고    scopus 로고
    • An enduring association? Microfilariae and immunosuppression [correction of immunosupression] in lymphatic filariasis
    • O'Connor RA, Jenson JS, Osborne J, Devaney E, (2003) An enduring association? Microfilariae and immunosuppression [correction of immunosupression] in lymphatic filariasis. Trends Parasitol 19: 565-570.
    • (2003) Trends Parasitol , vol.19 , pp. 565-570
    • O'Connor, R.A.1    Jenson, J.S.2    Osborne, J.3    Devaney, E.4
  • 63
    • 0028346084 scopus 로고
    • Long-term effect of prenatal exposure to maternal microfilaraemia on immune responsiveness to filarial parasite antigens
    • Steel C, Guinea A, McCarthy JS, Ottesen EA, (1994) Long-term effect of prenatal exposure to maternal microfilaraemia on immune responsiveness to filarial parasite antigens. Lancet 343: 890-893.
    • (1994) Lancet , vol.343 , pp. 890-893
    • Steel, C.1    Guinea, A.2    McCarthy, J.S.3    Ottesen, E.A.4
  • 65
    • 0141576694 scopus 로고    scopus 로고
    • Immune regulation by helminth parasites: cellular and molecular mechanisms
    • Maizels RM, Yazdanbakhsh M, (2003) Immune regulation by helminth parasites: cellular and molecular mechanisms. Nature reviews Immunology 3: 733-744.
    • (2003) Nature Reviews Immunology , vol.3 , pp. 733-744
    • Maizels, R.M.1    Yazdanbakhsh, M.2
  • 67
    • 0035914925 scopus 로고    scopus 로고
    • Determinants of viral clearance and persistence during acute hepatitis C virus infection
    • Thimme R, Oldach D, Chang KM, Steiger C, Ray SC, et al. (2001) Determinants of viral clearance and persistence during acute hepatitis C virus infection. J Exp Med 194: 1395-1406.
    • (2001) J Exp Med , vol.194 , pp. 1395-1406
    • Thimme, R.1    Oldach, D.2    Chang, K.M.3    Steiger, C.4    Ray, S.C.5
  • 68
    • 66049149509 scopus 로고    scopus 로고
    • Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood
    • Haringer B, Lozza L, Steckel B, Geginat J, (2009) Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood. J Exp Med 206: 1009-1017.
    • (2009) J Exp Med , vol.206 , pp. 1009-1017
    • Haringer, B.1    Lozza, L.2    Steckel, B.3    Geginat, J.4
  • 69
    • 12944310982 scopus 로고    scopus 로고
    • IL-10-producing T cells suppress immune responses in anergic tuberculosis patients
    • Boussiotis VA, Tsai EY, Yunis EJ, Thim S, Delgado JC, et al. (2000) IL-10-producing T cells suppress immune responses in anergic tuberculosis patients. J Clin Invest 105: 1317-1325.
    • (2000) J Clin Invest , vol.105 , pp. 1317-1325
    • Boussiotis, V.A.1    Tsai, E.Y.2    Yunis, E.J.3    Thim, S.4    Delgado, J.C.5
  • 70
    • 58149306013 scopus 로고    scopus 로고
    • In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure
    • Meiler F, Zumkehr J, Klunker S, Ruckert B, Akdis CA, et al. (2008) In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure. J Exp Med 205: 2887-2898.
    • (2008) J Exp Med , vol.205 , pp. 2887-2898
    • Meiler, F.1    Zumkehr, J.2    Klunker, S.3    Ruckert, B.4    Akdis, C.A.5
  • 71
    • 34249678457 scopus 로고    scopus 로고
    • T(H)1 cells control themselves by producing interleukin-10
    • O'Garra A, Vieira P, (2007) T(H)1 cells control themselves by producing interleukin-10. Nat Rev Immunol 7: 425-428.
    • (2007) Nat Rev Immunol , vol.7 , pp. 425-428
    • O'Garra, A.1    Vieira, P.2
  • 72
    • 0032797911 scopus 로고    scopus 로고
    • A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice
    • Li C, Corraliza I, Langhorne J, (1999) A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice. Infect Immun 67: 4435-4442.
    • (1999) Infect Immun , vol.67 , pp. 4435-4442
    • Li, C.1    Corraliza, I.2    Langhorne, J.3
  • 73
    • 0031741637 scopus 로고    scopus 로고
    • Reciprocal regulation of Th1- and Th2-cytokine-producing T cells during clearance of parasitemia in Plasmodium falciparum malaria
    • Winkler S, Willheim M, Baier K, Schmid D, Aichelburg A, et al. (1998) Reciprocal regulation of Th1- and Th2-cytokine-producing T cells during clearance of parasitemia in Plasmodium falciparum malaria. Infect Immun 66: 6040-6044.
    • (1998) Infect Immun , vol.66 , pp. 6040-6044
    • Winkler, S.1    Willheim, M.2    Baier, K.3    Schmid, D.4    Aichelburg, A.5
  • 74
    • 33645986702 scopus 로고    scopus 로고
    • Cellular reactivity to the p. Falciparum protein trap in adult kenyans: novel epitopes, complex cytokine patterns, and the impact of natural antigenic variation
    • Flanagan KL, Plebanski M, Odhiambo K, Sheu E, Mwangi T, et al. (2006) Cellular reactivity to the p. Falciparum protein trap in adult kenyans: novel epitopes, complex cytokine patterns, and the impact of natural antigenic variation. Am J Trop Med Hyg 74: 367-375.
    • (2006) Am J Trop Med Hyg , vol.74 , pp. 367-375
    • Flanagan, K.L.1    Plebanski, M.2    Odhiambo, K.3    Sheu, E.4    Mwangi, T.5
  • 75
    • 84855857015 scopus 로고    scopus 로고
    • T-cell responses to the DBLalpha-tag, a short semi-conserved region of the Plasmodium falciparum membrane erythrocyte protein 1
    • Gitau EN, Tuju J, Stevenson L, Kimani E, Karanja H, et al. (2012) T-cell responses to the DBLalpha-tag, a short semi-conserved region of the Plasmodium falciparum membrane erythrocyte protein 1. PLoS ONE 7: e30095.
    • (2012) PLoS ONE , vol.7
    • Gitau, E.N.1    Tuju, J.2    Stevenson, L.3    Kimani, E.4    Karanja, H.5
  • 76
    • 84873878906 scopus 로고    scopus 로고
    • Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure
    • Roetynck S, Olotu A, Simam J, Marsh K, Stockinger B, et al. (2013) Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure. PLoS ONE 8: e55195.
    • (2013) PLoS ONE , vol.8
    • Roetynck, S.1    Olotu, A.2    Simam, J.3    Marsh, K.4    Stockinger, B.5
  • 77
    • 84861680926 scopus 로고    scopus 로고
    • T cell-derived IL-10 and its impact on the regulation of host responses during malaria
    • Freitas do Rosario AP, Langhorne J, (2012) T cell-derived IL-10 and its impact on the regulation of host responses during malaria. International Journal for Parasitology 42: 549-555.
    • (2012) International Journal for Parasitology , vol.42 , pp. 549-555
    • Freitas do Rosario, A.P.1    Langhorne, J.2
  • 78
    • 79954997151 scopus 로고    scopus 로고
    • Filarial infection suppresses malaria-specific multifunctional Th1 and Th17 responses in malaria and filarial coinfections
    • Metenou S, Dembele B, Konate S, Dolo H, Coulibaly YI, et al. (2011) Filarial infection suppresses malaria-specific multifunctional Th1 and Th17 responses in malaria and filarial coinfections. Journal of immunology 186: 4725-4733.
    • (2011) Journal of Immunology , vol.186 , pp. 4725-4733
    • Metenou, S.1    Dembele, B.2    Konate, S.3    Dolo, H.4    Coulibaly, Y.I.5
  • 79
    • 19944432324 scopus 로고    scopus 로고
    • IFN-gamma and IL-10 mediate parasite-specific immune responses of cord blood cells induced by pregnancy-associated Plasmodium falciparum malaria
    • Brustoski K, Moller U, Kramer M, Petelski A, Brenner S, et al. (2005) IFN-gamma and IL-10 mediate parasite-specific immune responses of cord blood cells induced by pregnancy-associated Plasmodium falciparum malaria. Journal of immunology 174: 1738-1745.
    • (2005) Journal of Immunology , vol.174 , pp. 1738-1745
    • Brustoski, K.1    Moller, U.2    Kramer, M.3    Petelski, A.4    Brenner, S.5
  • 80
    • 67651087322 scopus 로고    scopus 로고
    • IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells
    • Brockman MA, Kwon DS, Tighe DP, Pavlik DF, Rosato PC, et al. (2009) IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells. Blood 114: 346-356.
    • (2009) Blood , vol.114 , pp. 346-356
    • Brockman, M.A.1    Kwon, D.S.2    Tighe, D.P.3    Pavlik, D.F.4    Rosato, P.C.5
  • 82
    • 79952379865 scopus 로고    scopus 로고
    • Inhibitory effect of TNF-alpha on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations
    • Depinay N, Franetich JF, Gruner AC, Mauduit M, Chavatte JM, et al. (2011) Inhibitory effect of TNF-alpha on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations. PLoS ONE 6: e17464.
    • (2011) PLoS ONE , vol.6
    • Depinay, N.1    Franetich, J.F.2    Gruner, A.C.3    Mauduit, M.4    Chavatte, J.M.5
  • 84
    • 72849137417 scopus 로고    scopus 로고
    • Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children
    • Katrak S, Gasasira A, Arinaitwe E, Kakuru A, Wanzira H, et al. (2009) Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children. Malaria Journal 8: 272.
    • (2009) Malaria Journal , vol.8 , pp. 272
    • Katrak, S.1    Gasasira, A.2    Arinaitwe, E.3    Kakuru, A.4    Wanzira, H.5
  • 85
    • 84858998763 scopus 로고    scopus 로고
    • Protective efficacy of co-trimoxazole prophylaxis against malaria in HIV exposed children in rural Uganda: a randomised clinical trial
    • Sandison TG, Homsy J, Arinaitwe E, Wanzira H, Kakuru A, et al. (2011) Protective efficacy of co-trimoxazole prophylaxis against malaria in HIV exposed children in rural Uganda: a randomised clinical trial. BMJ 342: d1617.
    • (2011) BMJ , vol.342
    • Sandison, T.G.1    Homsy, J.2    Arinaitwe, E.3    Wanzira, H.4    Kakuru, A.5
  • 86
    • 77957295341 scopus 로고    scopus 로고
    • Breastfeeding and the risk of malaria in children born to HIV-infected and uninfected mothers in rural Uganda
    • Vora N, Homsy J, Kakuru A, Arinaitwe E, Wanzira H, et al. (2010) Breastfeeding and the risk of malaria in children born to HIV-infected and uninfected mothers in rural Uganda. Journal of Acquired Immune Deficiency Syndromes 55: 253-261.
    • (2010) Journal of Acquired Immune Deficiency Syndromes , vol.55 , pp. 253-261
    • Vora, N.1    Homsy, J.2    Kakuru, A.3    Arinaitwe, E.4    Wanzira, H.5
  • 88
    • 84862515892 scopus 로고    scopus 로고
    • Kampala, Uganda: Uganda Ministry of Health
    • (2010) Uganda Clinical Guidelines 2010. National Guidelines on Management of Common Conditions. Kampala, Uganda: Uganda Ministry of Health.
    • (2010) Uganda Clinical Guidelines 2010
  • 89
    • 79952205266 scopus 로고    scopus 로고
    • Short-lived IFN-gamma effector responses, but long-lived IL-10 memory responses, to malaria in an area of low malaria endemicity
    • Wipasa J, Okell L, Sakkhachornphop S, Suphavilai C, Chawansuntati K, et al. (2011) Short-lived IFN-gamma effector responses, but long-lived IL-10 memory responses, to malaria in an area of low malaria endemicity. PLoS pathogens 7: e1001281.
    • (2011) PLoS Pathogens , vol.7
    • Wipasa, J.1    Okell, L.2    Sakkhachornphop, S.3    Suphavilai, C.4    Chawansuntati, K.5
  • 90
    • 77953380103 scopus 로고    scopus 로고
    • Cross-talk between T cells and NK cells generates rapid effector responses to Plasmodium falciparum-infected erythrocytes
    • Horowitz A, Newman KC, Evans JH, Korbel DS, Davis DM, et al. (2010) Cross-talk between T cells and NK cells generates rapid effector responses to Plasmodium falciparum-infected erythrocytes. J Immunol 184: 6043-6052.
    • (2010) J Immunol , vol.184 , pp. 6043-6052
    • Horowitz, A.1    Newman, K.C.2    Evans, J.H.3    Korbel, D.S.4    Davis, D.M.5
  • 91
    • 33749497954 scopus 로고    scopus 로고
    • Flow cytometry controls, instrument setup, and the determination of positivity
    • Maecker HT, Trotter J, (2006) Flow cytometry controls, instrument setup, and the determination of positivity. Cytometry Part A 69: 1037-1042.
    • (2006) Cytometry Part A , vol.69 , pp. 1037-1042
    • Maecker, H.T.1    Trotter, J.2
  • 92
    • 34347232370 scopus 로고    scopus 로고
    • Intracellular cytokine optimization and standard operating procedure
    • Lamoreaux L, Roederer M, Koup R, (2006) Intracellular cytokine optimization and standard operating procedure. Nat Protoc 1: 1507-1516.
    • (2006) Nat Protoc , vol.1 , pp. 1507-1516
    • Lamoreaux, L.1    Roederer, M.2    Koup, R.3
  • 93
    • 42949147530 scopus 로고    scopus 로고
    • Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach
    • McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, et al. (2008) Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach. Cytometry Part A 73: 400-410.
    • (2008) Cytometry Part A , vol.73 , pp. 400-410
    • McLaughlin, B.E.1    Baumgarth, N.2    Bigos, M.3    Roederer, M.4    De Rosa, S.C.5
  • 94
    • 79251515158 scopus 로고    scopus 로고
    • SPICE: Exploration and analysis of post-cytometric complex multivariate datasets
    • Roederer M, Nozzi JL, Nason MX, (2011) SPICE: Exploration and analysis of post-cytometric complex multivariate datasets. Cytometry Part A [Epub ahead of print].
    • (2011) Cytometry Part A
    • Roederer, M.1    Nozzi, J.L.2    Nason, M.X.3


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