Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Nature Immunology

Volumn 9, Issue 12, 2008, Pages 1399-1406

  El Kasmi, Karim C ^a,h   Qualls, Joseph E ^a   Pesce, John T ^b   Smith, Amber M ^a   Thompson, Robert W ^b   Henao Tamayo, Marcela ^c   Basaraba, Randall J ^c   König, Till ^d   Schleicher, Ulrike ^e   Koo, Mi Sun ^f   Kaplan, Gilla ^f   Fitzgerald, Katherine A ^g   Tuomanen, Elaine I ^a   Orme, Ian M ^c   Kanneganti, Thirumala Devi ^a   Bogdan, Christian ^e   Wynn, Thomas A ^b   Murray, Peter J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c Department of Environmental and Radiological Health Sciences   (United States)

^d UNIVERSITY OF FREIBURG   (Germany)

^e UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^f PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^g UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^h UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; INTERLEUKIN 13; INTERLEUKIN 4; STAT6 PROTEIN; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CELLULAR IMMUNITY; COCULTURE; CONTROLLED STUDY; HELPER CELL; HOST; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG TUBERCULOSIS; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURVIVAL; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ANIMALS; ARGINASE; BACTERIAL INFECTIONS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; STAT6 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTORS;

EID: 56349093356     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1671     Document Type: Article

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