-
1
-
-
33747593830
-
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
-
Stumhofer J.S., et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat. Immunol. 2006, 7:937-945.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 937-945
-
-
Stumhofer, J.S.1
-
2
-
-
0029959459
-
+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α
-
+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α. J. Immunol. 1996, 157:798-805.
-
(1996)
J. Immunol.
, vol.157
, pp. 798-805
-
-
Gazzinelli, R.T.1
-
3
-
-
22144487678
-
A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis
-
Wilson E.H., et al. A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis. J. Neuroimmunol. 2005, 165:63-74.
-
(2005)
J. Neuroimmunol.
, vol.165
, pp. 63-74
-
-
Wilson, E.H.1
-
4
-
-
79956077563
-
T cell exhaustion
-
Wherry E.J. T cell exhaustion. Nat. Immunol. 2011, 12:492-499.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 492-499
-
-
Wherry, E.J.1
-
5
-
-
84855911057
-
Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection
-
Butler N.S., et al. Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection. Nat. Immunol. 2012, 13:188-195.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 188-195
-
-
Butler, N.S.1
-
6
-
-
79959357729
-
+ T-cell response via PD-1-PDL-1 blockade
-
+ T-cell response via PD-1-PDL-1 blockade. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:9196-9201.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 9196-9201
-
-
Bhadra, R.1
-
7
-
-
84865159642
-
T cell exhaustion in protozoan disease
-
Gigley J.P., et al. T cell exhaustion in protozoan disease. Trends Parasitol. 2012, 28:377-384.
-
(2012)
Trends Parasitol.
, vol.28
, pp. 377-384
-
-
Gigley, J.P.1
-
8
-
-
0036721695
-
Murine malaria is exacerbated by CTLA-4 blockade
-
Jacobs T., et al. Murine malaria is exacerbated by CTLA-4 blockade. J. Immunol. 2002, 169:2323-2329.
-
(2002)
J. Immunol.
, vol.169
, pp. 2323-2329
-
-
Jacobs, T.1
-
9
-
-
3843133171
-
CTLA-4-dependent mechanisms prevent T cell induced-liver pathology during the erythrocyte stage of Plasmodium berghei malaria
-
Jacobs T., et al. CTLA-4-dependent mechanisms prevent T cell induced-liver pathology during the erythrocyte stage of Plasmodium berghei malaria. Eur. J. Immunol. 2004, 34:972-980.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 972-980
-
-
Jacobs, T.1
-
10
-
-
34247639547
-
CTLA-4 blockade differentially influences the outcome of non-lethal and lethal Plasmodium yoelii infections
-
Lepenies B., et al. CTLA-4 blockade differentially influences the outcome of non-lethal and lethal Plasmodium yoelii infections. Microbes Infect. 2007, 9:687-694.
-
(2007)
Microbes Infect.
, vol.9
, pp. 687-694
-
-
Lepenies, B.1
-
11
-
-
84860898062
-
The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology
-
Hafalla J.C., et al. The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathog. 2012, 8:e1002504.
-
(2012)
PLoS Pathog.
, vol.8
-
-
Hafalla, J.C.1
-
12
-
-
78651321282
-
+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo
-
+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo. PLoS Pathog. 2010, 6:e1001221.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Haque, A.1
-
13
-
-
77955298874
-
CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1
-
Charles E., et al. CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1. Infect. Immun. 2010, 78:3484-3492.
-
(2010)
Infect. Immun.
, vol.78
, pp. 3484-3492
-
-
Charles, E.1
-
14
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva M., O'Garra A. The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 2010, 10:170-181.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
-
15
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R., et al. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 1993, 75:263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
-
16
-
-
0034658617
-
IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii
-
Suzuki Y., et al. IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii. J. Immunol. 2000, 164:5375-5382.
-
(2000)
J. Immunol.
, vol.164
, pp. 5375-5382
-
-
Suzuki, Y.1
-
17
-
-
40349089873
-
IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection
-
Couper K.N., et al. IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. PLoS Pathog. 2008, 4:e1000004.
-
(2008)
PLoS Pathog.
, vol.4
-
-
Couper, K.N.1
-
18
-
-
33847144180
-
- Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
-
- Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J. Exp. Med. 2007, 204:273-283.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 273-283
-
-
Jankovic, D.1
-
19
-
-
9244237038
-
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation
-
Roers A., et al. T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J. Exp. Med. 2004, 200:1289-1297.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1289-1297
-
-
Roers, A.1
-
20
-
-
0041823567
-
Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor α and exacerbated by anti-transforming growth factor β antibodies
-
Li C., et al. Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor α and exacerbated by anti-transforming growth factor β antibodies. Infect. Immun. 2003, 71:4850-4856.
-
(2003)
Infect. Immun.
, vol.71
, pp. 4850-4856
-
-
Li, C.1
-
21
-
-
0030298362
-
Plasmodium chabaudi chabaudi: differential susceptibility of gene-targeted mice deficient in IL-10 to an erythrocytic-stage infection
-
Linke A., et al. Plasmodium chabaudi chabaudi: differential susceptibility of gene-targeted mice deficient in IL-10 to an erythrocytic-stage infection. Exp. Parasitol. 1996, 84:253-263.
-
(1996)
Exp. Parasitol.
, vol.84
, pp. 253-263
-
-
Linke, A.1
-
22
-
-
0042311279
-
Pathogenicity of Toxoplasma gondii through B-2 cell-mediated downregulation of host defense responses
-
Mun H.S., et al. Pathogenicity of Toxoplasma gondii through B-2 cell-mediated downregulation of host defense responses. Microbiol. Immunol. 2003, 47:533-542.
-
(2003)
Microbiol. Immunol.
, vol.47
, pp. 533-542
-
-
Mun, H.S.1
-
23
-
-
84856567798
-
+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection
-
+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. J. Immunol. 2012, 188:1178-1190.
-
(2012)
J. Immunol.
, vol.188
, pp. 1178-1190
-
-
Freitas do Rosario, A.P.1
-
24
-
-
57049122803
-
Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production
-
Ouma C., et al. Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production. Hum. Genet. 2008, 124:515-524.
-
(2008)
Hum. Genet.
, vol.124
, pp. 515-524
-
-
Ouma, C.1
-
25
-
-
22544458241
-
Analysis of IL10 haplotypic associations with severe malaria
-
Wilson J.N., et al. Analysis of IL10 haplotypic associations with severe malaria. Genes Immun. 2005, 6:462-466.
-
(2005)
Genes Immun.
, vol.6
, pp. 462-466
-
-
Wilson, J.N.1
-
26
-
-
33746128777
-
Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of Central India
-
Prakash D., et al. Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of Central India. J. Infect. Dis. 2006, 194:198-207.
-
(2006)
J. Infect. Dis.
, vol.194
, pp. 198-207
-
-
Prakash, D.1
-
27
-
-
79851506686
-
Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia
-
Thuma P.E., et al. Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia. J. Infect. Dis. 2011, 203:211-219.
-
(2011)
J. Infect. Dis.
, vol.203
, pp. 211-219
-
-
Thuma, P.E.1
-
28
-
-
80855157093
-
Identification of inflammatory biomarkers for pediatric malarial anemia severity using novel statistical methods
-
Ong'echa J.M., et al. Identification of inflammatory biomarkers for pediatric malarial anemia severity using novel statistical methods. Infect. Immun. 2011, 79:4674-4680.
-
(2011)
Infect. Immun.
, vol.79
, pp. 4674-4680
-
-
Ong'echa, J.M.1
-
29
-
-
84884214616
-
Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria
-
Pinzon-Charry A., et al. Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria. J. Exp. Med. 2013, 210:1635.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 1635
-
-
Pinzon-Charry, A.1
-
30
-
-
77953311223
-
Blood-stage Plasmodium berghei infection leads to short-lived parasite-associated antigen presentation by dendritic cells
-
Lundie R.J., et al. Blood-stage Plasmodium berghei infection leads to short-lived parasite-associated antigen presentation by dendritic cells. Eur. J. Immunol. 2010, 40:1674-1681.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 1674-1681
-
-
Lundie, R.J.1
-
31
-
-
0037013930
-
Mechanism of transforming growth factor β-induced inhibition of T helper type 1 differentiation
-
Gorelik L., et al. Mechanism of transforming growth factor β-induced inhibition of T helper type 1 differentiation. J. Exp. Med. 2002, 195:1499-1505.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1499-1505
-
-
Gorelik, L.1
-
32
-
-
48449086316
-
TGF-β: a master of all T cell trades
-
Li M.O., Flavell R.A. TGF-β: a master of all T cell trades. Cell 2008, 134:392-404.
-
(2008)
Cell
, vol.134
, pp. 392-404
-
-
Li, M.O.1
Flavell, R.A.2
-
33
-
-
0027440279
-
Profiles of cytokine production in relation with susceptibility to cerebral malaria
-
de Kossodo S., Grau G.E. Profiles of cytokine production in relation with susceptibility to cerebral malaria. J. Immunol. 1993, 151:4811-4820.
-
(1993)
J. Immunol.
, vol.151
, pp. 4811-4820
-
-
de Kossodo, S.1
Grau, G.E.2
-
34
-
-
84868104207
-
Cerebral malaria: we have come a long way
-
Shikani H.J., et al. Cerebral malaria: we have come a long way. Am. J. Pathol. 2012, 181:1484-1492.
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 1484-1492
-
-
Shikani, H.J.1
-
35
-
-
0035168870
-
Inverse relationship of plasma prostaglandin E2 and blood mononuclear cell cyclooxygenase-2 with disease severity in children with Plasmodium falciparum malaria
-
Perkins D.J., et al. Inverse relationship of plasma prostaglandin E2 and blood mononuclear cell cyclooxygenase-2 with disease severity in children with Plasmodium falciparum malaria. J. Infect. Dis. 2001, 183:113-118.
-
(2001)
J. Infect. Dis.
, vol.183
, pp. 113-118
-
-
Perkins, D.J.1
-
36
-
-
77953616680
-
Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease
-
de Souza J.B., et al. Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. Parasitology 2010, 137:755-772.
-
(2010)
Parasitology
, vol.137
, pp. 755-772
-
-
de Souza, J.B.1
-
37
-
-
84863621019
-
+ T cell accumulation within the brain
-
+ T cell accumulation within the brain. J. Immunol. 2012, 189:968-979.
-
(2012)
J. Immunol.
, vol.189
, pp. 968-979
-
-
Villegas-Mendez, A.1
-
38
-
-
84880003358
-
Brain microvessel cross-presentation is a hallmark of experimental cerebral malaria
-
Howland S.W., et al. Brain microvessel cross-presentation is a hallmark of experimental cerebral malaria. EMBO Mol. Med. 2013, 5:984-999.
-
(2013)
EMBO Mol. Med.
, vol.5
, pp. 984-999
-
-
Howland, S.W.1
-
39
-
-
68249141869
-
+ T cells
-
+ T cells. Immunity 2009, 31:131-144.
-
(2009)
Immunity
, vol.31
, pp. 131-144
-
-
Sanjabi, S.1
-
40
-
-
84862675985
-
Neuronal gp130 expression is crucial to prevent neuronal loss, hyperinflammation, and lethal course of murine Toxoplasma encephalitis
-
Handel U., et al. Neuronal gp130 expression is crucial to prevent neuronal loss, hyperinflammation, and lethal course of murine Toxoplasma encephalitis. Am. J. Pathol. 2012, 181:163-173.
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 163-173
-
-
Handel, U.1
-
41
-
-
0035123650
-
Murine ileitis after intracellular parasite infection is controlled by TGF-β-producing intraepithelial lymphocytes
-
Buzoni-Gatel D., et al. Murine ileitis after intracellular parasite infection is controlled by TGF-β-producing intraepithelial lymphocytes. Gastroenterology 2001, 120:914-924.
-
(2001)
Gastroenterology
, vol.120
, pp. 914-924
-
-
Buzoni-Gatel, D.1
-
42
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E., et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006, 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
-
43
-
-
0038326688
-
Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
-
Takeda A., et al. Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J. Immunol. 2003, 170:4886-4890.
-
(2003)
J. Immunol.
, vol.170
, pp. 4886-4890
-
-
Takeda, A.1
-
44
-
-
84861170066
-
The immunobiology of IL-27
-
Hall A.O., et al. The immunobiology of IL-27. Adv. Immunol. 2012, 115:1-44.
-
(2012)
Adv. Immunol.
, vol.115
, pp. 1-44
-
-
Hall, A.O.1
-
45
-
-
29644443883
-
IL-27 limits IL-2 production during Th1 differentiation
-
Villarino A.V., et al. IL-27 limits IL-2 production during Th1 differentiation. J. Immunol. 2006, 176:237-247.
-
(2006)
J. Immunol.
, vol.176
, pp. 237-247
-
-
Villarino, A.V.1
-
46
-
-
84866483591
-
The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology
-
Hall A.O., et al. The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology. Immunity 2012, 37:511-523.
-
(2012)
Immunity
, vol.37
, pp. 511-523
-
-
Hall, A.O.1
-
47
-
-
77956899787
-
Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection
-
Findlay E.G., et al. Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. J. Immunol. 2010, 185:2482-2492.
-
(2010)
J. Immunol.
, vol.185
, pp. 2482-2492
-
-
Findlay, E.G.1
-
48
-
-
84876793137
-
IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals
-
Villegas-Mendez A., et al. IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals. PLoS Pathog. 2013, 9:e1003293.
-
(2013)
PLoS Pathog.
, vol.9
-
-
Villegas-Mendez, A.1
-
49
-
-
84876811708
-
+ T cell chemotactic responses during infection
-
+ T cell chemotactic responses during infection. J. Immunol. 2013, 190:4553-4561.
-
(2013)
J. Immunol.
, vol.190
, pp. 4553-4561
-
-
Gwyer Findlay, E.1
-
50
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer J.S., et al. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat. Immunol. 2007, 8:1363-1371.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
-
51
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
-
Awasthi A., et al. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat. Immunol. 2007, 8:1380-1389.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
-
52
-
-
48749107414
-
+ inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii
-
+ inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii. Immunity 2008, 29:306-317.
-
(2008)
Immunity
, vol.29
, pp. 306-317
-
-
Dunay, I.R.1
-
53
-
-
22344454821
-
+ monocytes is essential for control of acute toxoplasmosis
-
+ monocytes is essential for control of acute toxoplasmosis. J. Exp. Med. 2005, 201:1761-1769.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1761-1769
-
-
Robben, P.M.1
-
54
-
-
76249109239
-
Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria
-
Sponaas A.M., et al. Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria. Blood 2009, 114:5522-5531.
-
(2009)
Blood
, vol.114
, pp. 5522-5531
-
-
Sponaas, A.M.1
-
55
-
-
84880285461
-
Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection
-
Grainger J.R., et al. Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection. Nat. Med. 2013, 19:713-721.
-
(2013)
Nat. Med.
, vol.19
, pp. 713-721
-
-
Grainger, J.R.1
-
56
-
-
84871700560
-
Monocytes and macrophages in malaria: protection or pathology?
-
Chua C.L., et al. Monocytes and macrophages in malaria: protection or pathology?. Trends Parasitol. 2013, 29:26-34.
-
(2013)
Trends Parasitol.
, vol.29
, pp. 26-34
-
-
Chua, C.L.1
-
57
-
-
40449105455
-
Plasmodium infection and endotoxic shock induce the expansion of regulatory dendritic cells
-
Wong K.A., Rodriguez A. Plasmodium infection and endotoxic shock induce the expansion of regulatory dendritic cells. J. Immunol. 2008, 180:716-726.
-
(2008)
J. Immunol.
, vol.180
, pp. 716-726
-
-
Wong, K.A.1
Rodriguez, A.2
-
58
-
-
10344239885
-
Stromal cells direct local differentiation of regulatory dendritic cells
-
Svensson M., et al. Stromal cells direct local differentiation of regulatory dendritic cells. Immunity 2004, 21:805-816.
-
(2004)
Immunity
, vol.21
, pp. 805-816
-
-
Svensson, M.1
-
59
-
-
70049100538
-
Plasmodium falciparum-mediated induction of human CD25Foxp3 CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFβ
-
Scholzen A., et al. Plasmodium falciparum-mediated induction of human CD25Foxp3 CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFβ. PLoS Pathog. 2009, 5:e1000543.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Scholzen, A.1
-
60
-
-
84875498856
-
Development and maintenance of regulatory T cells
-
Ohkura N., et al. Development and maintenance of regulatory T cells. Immunity 2013, 38:414-423.
-
(2013)
Immunity
, vol.38
, pp. 414-423
-
-
Ohkura, N.1
-
61
-
-
84859416933
-
Regulatory T cells: mechanisms of differentiation and function
-
Josefowicz S.Z., et al. Regulatory T cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 2012, 30:531-564.
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
-
62
-
-
84859316999
-
+ regulatory T cells, immune stimulation and host defence against infection
-
+ regulatory T cells, immune stimulation and host defence against infection. Immunology 2012, 136:1-10.
-
(2012)
Immunology
, vol.136
, pp. 1-10
-
-
Rowe, J.H.1
-
63
-
-
24944466472
-
+ regulatory T cells correlates with more rapid parasite growth in human malaria infection
-
+ regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity 2005, 23:287-296.
-
(2005)
Immunity
, vol.23
, pp. 287-296
-
-
Walther, M.1
-
64
-
-
66349085903
-
Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria
-
Walther M., et al. Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria. PLoS Pathog. 2009, 5:e1000364.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Walther, M.1
-
65
-
-
66349138519
-
Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria
-
Minigo G., et al. Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria. PLoS Pathog. 2009, 5:e1000402.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Minigo, G.1
-
66
-
-
72149128886
-
Heroes or villains? T regulatory cells in malaria infection
-
Scholzen A., et al. Heroes or villains? T regulatory cells in malaria infection. Trends Parasitol. 2010, 26:16-25.
-
(2010)
Trends Parasitol.
, vol.26
, pp. 16-25
-
-
Scholzen, A.1
-
67
-
-
84861680926
-
T cell-derived IL-10 and its impact on the regulation of host responses during malaria
-
Freitas do Rosario A.P., Langhorne J. T cell-derived IL-10 and its impact on the regulation of host responses during malaria. Int. J. Parasitol. 2012, 42:549-555.
-
(2012)
Int. J. Parasitol.
, vol.42
, pp. 549-555
-
-
Freitas do Rosario, A.P.1
Langhorne, J.2
-
68
-
-
64249129200
-
Anti-CD25 antibody-mediated depletion of effector T cell populations enhances susceptibility of mice to acute but not chronic Toxoplasma gondii infection
-
Couper K.N., et al. Anti-CD25 antibody-mediated depletion of effector T cell populations enhances susceptibility of mice to acute but not chronic Toxoplasma gondii infection. J. Immunol. 2009, 182:3985-3994.
-
(2009)
J. Immunol.
, vol.182
, pp. 3985-3994
-
-
Couper, K.N.1
-
69
-
-
70449532980
-
+ Treg cell number and acquisition of effector cell phenotype during lethal infection
-
+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity 2009, 31:772-786.
-
(2009)
Immunity
, vol.31
, pp. 772-786
-
-
Oldenhove, G.1
-
70
-
-
84856022105
-
Microbial infection-induced expansion of effector T cells overcomes the suppressive effects of regulatory T cells via an IL-2 deprivation mechanism
-
Benson A., et al. Microbial infection-induced expansion of effector T cells overcomes the suppressive effects of regulatory T cells via an IL-2 deprivation mechanism. J. Immunol. 2012, 188:800-810.
-
(2012)
J. Immunol.
, vol.188
, pp. 800-810
-
-
Benson, A.1
-
71
-
-
0032936299
-
CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1
-
Perez-Villar J.J., et al. CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1. Mol. Cell. Biol. 1999, 19:2903-2912.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2903-2912
-
-
Perez-Villar, J.J.1
-
72
-
-
0036136877
-
CD5-negative regulation of B cell receptor signaling pathways originates from tyrosine residue Y429 outside an immunoreceptor tyrosine-based inhibitory motif
-
Gary-Gouy H., et al. CD5-negative regulation of B cell receptor signaling pathways originates from tyrosine residue Y429 outside an immunoreceptor tyrosine-based inhibitory motif. J. Immunol. 2002, 168:232-239.
-
(2002)
J. Immunol.
, vol.168
, pp. 232-239
-
-
Gary-Gouy, H.1
-
73
-
-
84873601139
-
IL-10-producing regulatory B cells (B10 cells) in autoimmune disease
-
Kalampokis I., et al. IL-10-producing regulatory B cells (B10 cells) in autoimmune disease. Arthritis Res. Ther. 2013, 15(Suppl. 1):S1.
-
(2013)
Arthritis Res. Ther.
, vol.15
, Issue.SUPPL. 1
-
-
Kalampokis, I.1
-
74
-
-
84867150475
-
+ regulatory B cells following Babesia microti-infection
-
+ regulatory B cells following Babesia microti-infection. PLoS ONE 2012, 7:e46553.
-
(2012)
PLoS ONE
, vol.7
-
-
Jeong, Y.I.1
-
75
-
-
84872826792
-
Development of adult worms and granulomatous pathology are collectively regulated by T- and B-cells in mice infected with Schistosoma japonicum
-
Tang H., et al. Development of adult worms and granulomatous pathology are collectively regulated by T- and B-cells in mice infected with Schistosoma japonicum. PLoS ONE 2013, 8:e54432.
-
(2013)
PLoS ONE
, vol.8
-
-
Tang, H.1
-
76
-
-
33644867314
-
Regulating immunity to malaria
-
Riley E.M., et al. Regulating immunity to malaria. Parasite Immunol. 2006, 28:35-49.
-
(2006)
Parasite Immunol.
, vol.28
, pp. 35-49
-
-
Riley, E.M.1
-
77
-
-
0041378119
-
Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria
-
Hunt N.H., Grau G.E. Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends Immunol. 2003, 24:491-499.
-
(2003)
Trends Immunol.
, vol.24
, pp. 491-499
-
-
Hunt, N.H.1
Grau, G.E.2
-
78
-
-
0025045107
-
+ T cells in the protective immune response to Plasmodium chabaudi in vivo
-
+ T cells in the protective immune response to Plasmodium chabaudi in vivo. Immunol. Lett. 1990, 25:101-107.
-
(1990)
Immunol. Lett.
, vol.25
, pp. 101-107
-
-
Langhorne, J.1
-
79
-
-
0025107812
-
Role of γ interferon during infection with Plasmodium chabaudi chabaudi
-
Meding S.J., et al. Role of γ interferon during infection with Plasmodium chabaudi chabaudi. Infect. Immun. 1990, 58:3671-3678.
-
(1990)
Infect. Immun.
, vol.58
, pp. 3671-3678
-
-
Meding, S.J.1
-
80
-
-
23944469910
-
+ T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance
-
+ T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance. Blood 2005, 106:1676-1684.
-
(2005)
Blood
, vol.106
, pp. 1676-1684
-
-
Stephens, R.1
-
81
-
-
84865287151
-
T cell control of malaria pathogenesis
-
Spence P.J., Langhorne J. T cell control of malaria pathogenesis. Curr. Opin. Immunol. 2012, 24:444-448.
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 444-448
-
-
Spence, P.J.1
Langhorne, J.2
-
82
-
-
26044470703
-
Biology and epidemiology of Toxoplasma gondii in man and animals
-
Hill D.E., et al. Biology and epidemiology of Toxoplasma gondii in man and animals. Anim. Health Res. Rev. 2005, 6:41-61.
-
(2005)
Anim. Health Res. Rev.
, vol.6
, pp. 41-61
-
-
Hill, D.E.1
-
83
-
-
58849137119
-
Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection
-
Bierly A.L., et al. Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection. J. Immunol. 2008, 181:8485-8491.
-
(2008)
J. Immunol.
, vol.181
, pp. 8485-8491
-
-
Bierly, A.L.1
-
84
-
-
0023895411
-
Interferon-γ: the major mediator of resistance against Toxoplasma gondii
-
Suzuki Y., et al. Interferon-γ: the major mediator of resistance against Toxoplasma gondii. Science 1988, 240:516-518.
-
(1988)
Science
, vol.240
, pp. 516-518
-
-
Suzuki, Y.1
-
85
-
-
80051915459
-
+ dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites
-
+ dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites. Immunity 2011, 35:249-259.
-
(2011)
Immunity
, vol.35
, pp. 249-259
-
-
Mashayekhi, M.1
-
86
-
-
0027939611
-
Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii
-
Gazzinelli R.T., et al. Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii. J. Immunol. 1994, 153:2533-2543.
-
(1994)
J. Immunol.
, vol.153
, pp. 2533-2543
-
-
Gazzinelli, R.T.1
-
87
-
-
0028272528
-
Production of γ interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor α
-
Hunter C.A., et al. Production of γ interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor α. Infect. Immun. 1994, 62:2818-2824.
-
(1994)
Infect. Immun.
, vol.62
, pp. 2818-2824
-
-
Hunter, C.A.1
-
88
-
-
0037097795
-
Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells
-
Scanga C.A., et al. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. J. Immunol. 2002, 168:5997-6001.
-
(2002)
J. Immunol.
, vol.168
, pp. 5997-6001
-
-
Scanga, C.A.1
-
89
-
-
84872761427
-
Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii
-
Koblansky A.A., et al. Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii. Immunity 2013, 38:119-130.
-
(2013)
Immunity
, vol.38
, pp. 119-130
-
-
Koblansky, A.A.1
-
90
-
-
20644433342
-
TLR11 activation of dendritic cells by a protozoan profilin-like protein
-
Yarovinsky F., et al. TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science 2005, 308:1626-1629.
-
(2005)
Science
, vol.308
, pp. 1626-1629
-
-
Yarovinsky, F.1
-
91
-
-
84888137927
-
Toll-like receptor 7 mediates early innate immune responses to malaria
-
Baccarella A., et al. Toll-like receptor 7 mediates early innate immune responses to malaria. Infect. Immun. 2013, 10.1128/IAI.00923-13.
-
(2013)
Infect. Immun.
-
-
Baccarella, A.1
-
92
-
-
19944430901
-
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
-
Coban C., et al. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J. Exp. Med. 2005, 201:19-25.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 19-25
-
-
Coban, C.1
-
93
-
-
0033565408
-
+ T cells in the Plasmodium yoelii model
-
+ T cells in the Plasmodium yoelii model. J. Immunol. 1999, 163:884-892.
-
(1999)
J. Immunol.
, vol.163
, pp. 884-892
-
-
Doolan, D.L.1
Hoffman, S.L.2
-
94
-
-
84863007648
-
NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection
-
Goldszmid R.S., et al. NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection. Immunity 2012, 36:1047-1059.
-
(2012)
Immunity
, vol.36
, pp. 1047-1059
-
-
Goldszmid, R.S.1
-
95
-
-
35748974538
-
Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells
-
Dzierszinski F., et al. Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells. Infect. Immun. 2007, 75:5200-5209.
-
(2007)
Infect. Immun.
, vol.75
, pp. 5200-5209
-
-
Dzierszinski, F.1
-
96
-
-
18644375874
-
+ T cells by exogenous cell-associated antigens
-
+ T cells by exogenous cell-associated antigens. Immunity 2002, 17:211-220.
-
(2002)
Immunity
, vol.17
, pp. 211-220
-
-
Jung, S.1
-
97
-
-
2442666530
-
Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors
-
Del Rio L., et al. Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors. J. Immunol. 2004, 172:6954-6960.
-
(2004)
J. Immunol.
, vol.172
, pp. 6954-6960
-
-
Del Rio, L.1
-
98
-
-
9244250314
-
Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control
-
Vossenkamper A., et al. Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control. Eur. J. Immunol. 2004, 34:3197-3207.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 3197-3207
-
-
Vossenkamper, A.1
-
99
-
-
0033526013
-
Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-γ- and tumor necrosis factor (TNF)-α-dependent host resistance to the intracellular pathogen, Toxoplasma gondii
-
Yap G.S., Sher A. Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-γ- and tumor necrosis factor (TNF)-α-dependent host resistance to the intracellular pathogen, Toxoplasma gondii. J. Exp. Med. 1999, 189:1083-1092.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1083-1092
-
-
Yap, G.S.1
Sher, A.2
-
100
-
-
0033710213
-
IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection
-
Khan I.A., et al. IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection. Immunity 2000, 12:483-494.
-
(2000)
Immunity
, vol.12
, pp. 483-494
-
-
Khan, I.A.1
-
101
-
-
34347383750
-
Malarial anemia: of mice and men
-
Lamikanra A.A., et al. Malarial anemia: of mice and men. Blood 2007, 110:18-28.
-
(2007)
Blood
, vol.110
, pp. 18-28
-
-
Lamikanra, A.A.1
-
102
-
-
78649848029
-
Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria
-
Amante F.H., et al. Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria. J. Immunol. 2010, 185:3632-3642.
-
(2010)
J. Immunol.
, vol.185
, pp. 3632-3642
-
-
Amante, F.H.1
-
103
-
-
0029841124
-
+ T cell-dependent, interferon-γ-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii
-
+ T cell-dependent, interferon-γ-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J. Exp. Med. 1996, 184:597-607.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 597-607
-
-
Liesenfeld, O.1
-
104
-
-
65549146491
-
Immunopathology in ocular toxoplasmosis: facts and clues
-
Garweg J.G., Candolfi E. Immunopathology in ocular toxoplasmosis: facts and clues. Mem. Inst. Oswaldo Cruz 2009, 104:211-220.
-
(2009)
Mem. Inst. Oswaldo Cruz
, vol.104
, pp. 211-220
-
-
Garweg, J.G.1
Candolfi, E.2
-
105
-
-
67349248861
-
Toxoplasmosis: a history of clinical observations
-
Weiss L.M., Dubey J.P. Toxoplasmosis: a history of clinical observations. Int. J. Parasitol. 2009, 39:895-901.
-
(2009)
Int. J. Parasitol.
, vol.39
, pp. 895-901
-
-
Weiss, L.M.1
Dubey, J.P.2
-
106
-
-
77951564328
-
Natural regulatory T cells mediate the development of cerebral malaria by modifying the pro-inflammatory response
-
Wu J.J., et al. Natural regulatory T cells mediate the development of cerebral malaria by modifying the pro-inflammatory response. Parasitol. Int. 2010, 59:232-241.
-
(2010)
Parasitol. Int.
, vol.59
, pp. 232-241
-
-
Wu, J.J.1
-
107
-
-
0028152937
-
Transforming growth factor β: the good, the bad, and the ugly
-
Wahl S.M. Transforming growth factor β: the good, the bad, and the ugly. J. Exp. Med. 1994, 180:1587-1590.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1587-1590
-
-
Wahl, S.M.1
-
108
-
-
0036020271
-
Endocrine expression of the active form of TGF-β1 in the TGF-β1 null mice fails to ameliorate lethal phenotype
-
Longenecker G., et al. Endocrine expression of the active form of TGF-β1 in the TGF-β1 null mice fails to ameliorate lethal phenotype. Cytokine 2002, 18:43-50.
-
(2002)
Cytokine
, vol.18
, pp. 43-50
-
-
Longenecker, G.1
-
109
-
-
0036091906
-
Transforming growth factor-β expression in human retinal pigment epithelial cells is enhanced by Toxoplasma gondii: a possible role in the immunopathogenesis of retinochoroiditis
-
Nagineni C.N., et al. Transforming growth factor-β expression in human retinal pigment epithelial cells is enhanced by Toxoplasma gondii: a possible role in the immunopathogenesis of retinochoroiditis. Clin. Exp. Immunol. 2002, 128:372-378.
-
(2002)
Clin. Exp. Immunol.
, vol.128
, pp. 372-378
-
-
Nagineni, C.N.1
-
110
-
-
69249083836
-
Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
-
Pot C., et al. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J. Immunol. 2009, 183:797-801.
-
(2009)
J. Immunol.
, vol.183
, pp. 797-801
-
-
Pot, C.1
|