Tuning of peroxiredoxin catalysis for various physiological roles

Biochemistry

Volumn 53, Issue 49, 2014, Pages 7693-7705

  Perkins, Arden ^a   Poole, Leslie B ^b   Karplus, P Andrew ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; ENZYMES; OXIDATION; PEROXIDES; QUANTUM CHEMISTRY;

CATALYTIC MECHANISMS; CATALYTIC RESIDUE; ECOLOGICAL NICHE; ENZYMATIC FUNCTIONS; HOST IMMUNE RESPONSE; ORGANIC HYDROPEROXIDES; PHYSIOLOGICAL ROLES; SELECTIVE INHIBITION;

PHYSIOLOGY;

PEROXIREDOXIN; PEROXIREDOXIN 2; PEROXIREDOXIN 3; CYSTEINE; ENZYME INHIBITOR; ISOENZYME; OXIDOREDUCTASE; SRXN1 PROTEIN, HUMAN;

CATALYSIS; DRUG DESIGN; DRUG TARGETING; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE SILENCING; HUMAN; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOCATALYSIS; CHEMISTRY; ENZYME ACTIVATION; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; PHYLOGENY; PROTEIN STABILITY;

EUKARYOTA;

ANIMALS; BIOCATALYSIS; CYSTEINE; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; ISOENZYMES; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON SULFUR GROUP DONORS; PEROXIREDOXINS; PHYLOGENY; PROTEIN STABILITY; SUBSTRATE SPECIFICITY;

EID: 84918511722     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi5013222     Document Type: Review

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