Leishmania mitochondrial peroxiredoxin plays a crucial peroxidase-unrelated role during infection: Insight into its novel chaperone activity

PLoS Pathogens

Volumn 7, Issue 10, 2011, Pages

  Castro, Helena ^a   Teixeira, Filipa ^a   Romao, Susana ^a   Santos, Mariana ^a   Cruz, Tânia ^a   Flórido, Manuela ^a   Appelberg, Rui ^a,b   Oliveira, Pedro ^b   Ferreira da Silva, Frederico ^a   Tomás, Ana M ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MITOCHONDRIAL PROTEIN; PEROXIDASE; PEROXIREDOXIN; PROTOZOAL PROTEIN; CHAPERONE; CITRATE SYNTHASE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; HOST PARASITE INTERACTION; LEISHMANIA INFANTUM; LEISHMANIASIS; MACROPHAGE; MOUSE; NONHUMAN; OPEN READING FRAME; OXIDATIVE STRESS; PARASITE SURVIVAL; PATHOGENICITY; PHAGOCYTE; PHAGOCYTOSIS; PHENOTYPE; PROMASTIGOTE; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; WILD TYPE; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; LEISHMANIA; METABOLISM; MITOCHONDRION; MOUSE MUTANT; PARASITE LOAD; PARASITOLOGY;

LEISHMANIA INFANTUM; MURINAE; MUS; TRYPANOSOMATIDAE;

ANIMALS; CELLS, CULTURED; CITRATE (SI)-SYNTHASE; DISEASE MODELS, ANIMAL; HOST-PARASITE INTERACTIONS; LEISHMANIA; LEISHMANIASIS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MOLECULAR CHAPERONES; PARASITE LOAD; PEROXIREDOXINS;

EID: 80055096383     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002325     Document Type: Article

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