Lung injury and mortality with hyperoxia are increased in Peroxiredoxin 6 gene-targeted mice

Free Radical Biology and Medicine

Volumn 37, Issue 11, 2004, Pages 1736-1743

  Wang, Yan ^a   Feinstein, Sheldon I ^a   Manevich, Yefim ^a   Ho, Ye Shih ^b   Fisher, Aron B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

1 Cys peroxiredoxin; Bonchoalveolar lavage fluid; Free radicals; Lipid peroxidation; Oxidant stress; Protein carbonyls

Indexed keywords

PEROXIREDOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRY WEIGHT; EDEMA; EPITHELIUM CELL; GENE INACTIVATION; GENE TARGETING; HISTOPATHOLOGY; HYPEROXIA; LUNG HOMOGENATE; LUNG INJURY; LUNG LAVAGE; MALE; MICROSCOPY; MORTALITY; MOUSE; NONHUMAN; OXIDATION; OXYGEN TOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; SURVIVAL; WILD TYPE;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; GENE TARGETING; HYPEROXIA; LUNG; MICE; MICE, MUTANT STRAINS; OXIDATIVE STRESS; PEROXIDASES; PROTEINS; SURVIVAL ANALYSIS; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 7444247318     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.09.006     Document Type: Article

References (34)

1. A.B. Fisher, H.J. Forman, and M. Glass Mechanisms of pulmonary oxygen toxicity Lung 162 1984 255 259
2. B.A. Freeman, and J.D. Crapo Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria J. Biol. Chem. 256 1981 10986 10992
3. L.L. Mantell, S. Horowitz, J.M. Davis, and J.A. Kazzaz Hyperoxia-induced cell death in the lung-the correlation of apoptosis, necrosis, and inflammation Ann. N. Y. Acad. Sci. 887 1999 171 180
4. T.M. Asikainen, T.T. Huang, E. Taskinen, A.L. Levonen, E. Carlson, R. Lapatto, C.J. Epstein, and K.O. Raivio Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity Free Radic. Biol. Med. 32 2002 175 186
5. C. Danel, S.C. Erzurum, P. Prayssac, N.T. Eissa, R.G. Crystal, P. Herve, B. Baudet, M. Mazmanian, and P. Lemarchand Gene therapy for oxidant injury-related diseases: adenovirus-mediated transfer of superoxide dismutase and catalase cDNAs protects against hyperoxia but not against ischemia-reperfusion lung injury Hum. Gene Ther. 9 1998 1487 1496
6. Y.S. Ho, J.L. Magnenat, R.T. Bronson, J. Cao, M. Gargano, M. Sugawara, and C.D. Funk Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia J. Biol. Chem. 272 1997 16644 16651
7. Y.S. Ho, R. Vincent, M.S. Dey, J.W. Slot, and J.D. Crapo Transgenic models for the study of lung antioxidant defense: enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia Am. J. Respir. Cell. Mol. Biol. 18 1998 538 547
8. C.W. White, K.B. Avraham, P.F. Shanley, and Y. Groner Transgenic mice with expression of elevated levels of copper-zinc superoxide dismutase in the lungs are resistant to pulmonary oxygen toxicity J. Clin. Invest. 87 1991 2162 2168
9. J.R. Wispe, B.B. Warner, J.C. Clark, C.R. Dey, J. Neuman, S.W. Glasser, J.D. Crapo, L.Y. Chang, and J.A. Whitsett Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury J. Biol. Chem. 267 1992 23937 23941
10. Y.S. Ho Transgenic and knockout models for studying the role of lung antioxidant enzymes in defense against hyperoxia Am. J. Respir. Crit. Care Med. 166 2002 S51 S56
11. A.B. Fisher, C. Dodia, Y. Manevich, J.W. Chen, and S.I. Feinstein Phospholipid hydroperoxides are substrates for non-selenium glutathione peroxidase J. Biol. Chem. 274 1999 21326 21334
12. T.S. Kim, C. Dodia, X. Chen, B.B. Hennigan, M. Jain, S.I. Feinstein, and A.B. Fisher Cloning and expression of rat lung acidic Ca(2+)-independent PLA2 and its organ distribution Am. J. Physiol. 274 1998 L750 L761
13. S.W. Kang, I.C. Baines, and S.G. Rhee Characterization of a mammalian peroxiredoxin that contains one conserved cysteine J. Biol. Chem. 273 1998 6303 6311
14. Y. Manevich, T. Sweitzer, J.H. Pak, S.I. Feinstein, V. Muzykantov, and A.B. Fisher 1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage Proc. Natl. Acad. Sci. USA 99 2002 11599 11604
15. J.H. Pak, Y. Manevich, H.S. Kim, S.I. Feinstein, and A.B. Fisher An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells J. Biol. Chem. 277 2002 49927 49934
16. Y. Wang, Y. Manevich, S.I. Feinstein, and A.B. Fisher Adenovirus-mediated transfer of the 1-cys peroxiredoxin gene to mouse lung protects against hyperoxic injury Am. J. Physiol. Lung Cell. Mol. Physiol. 286 2004 1188 1193
17. X. Wang, S.A. Phelan, K. Forsman-Semb, E.F. Taylor, C. Petros, A. Brown, C.P. Lerner, and B. Paigen Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress J. Biol. Chem. 278 2003 25179 25190
18. Y. Mo, S.I. Feinstein, Y. Manevich, Q. Zhang, L. Lu, Y.S. Ho, and A.B. Fisher 1-Cys peroxiredoxin knock-out mice express mRNA but not protein for a highly related intronless gene FEBS Lett. 555 2003 192 198
19. I.S. Ayene, C. Dodia, and A.B. Fisher Role of oxygen in oxidation of lipid and protein during ischemia/reperfusion in isolated perfused rat lung Arch. Biochem. Biophys. 296 1992 183 189
20. J.C. Gonder, R.A. Proctor, and J.A. Will Genetic differences in oxygen toxicity are correlated with cytochrome P-450 inducibility Proc. Natl. Acad. Sci. USA 82 1985 6315 6319
21. C.J. Johnston, B.R. Stripp, B. Piedbeouf, T.W. Wright, G.W. Mango, C.K. Reed, and J.N. Finkelstein Inflammatory and epithelial responses in mouse strains that differ in sensitivity to hyperoxic injury Exp. Lung Res. 24 1998 189 202
22. B. Piedboeuf, C.J. Johnston, R.H. Watkins, B.B. Hudak, J.S. Lazo, M.G. Cherian, and S. Horowitz Increased expression of tissue inhibitor of metalloproteinases (TIMP-I) and metallothionein in murine lungs after hyperoxic exposure Am. J. Respir. Cell. Mol. Biol. 10 1994 123 132
23. D.T. Wright, L.A. Cohn, H. Li, B. Fischer, C.M. Li, and K.B. Adler Interactions of oxygen radicals with airway epithelium Environ. Health Perspect. 102 Suppl 10 1994 85 90
24. Y.S. Ho, M.S. Dey, and J.D. Crapo Antioxidant enzyme expression in rat lungs during hyperoxia Am. J. Physiol. 270 1996 L810 L818
25. C. Aerts, B. Wallaert, and C. Voisin In vitro effects of hyperoxia on alveolar type II pneumocytes: inhibition of glutathione synthesis increases hyperoxic cell injury Exp. Lung Res. 18 1992 845 861
26. L.A. Brown, J.A. Perez, F.L. Harris, and R.H. Clark Glutathione supplements protect preterm rabbits from oxidative lung injury Am. J. Physiol. 270 1996 L446 L451
27. N.A. Christie, A.S. Slutsky, B.A. Freeman, and A.K. Tanswell A critical role for thiol, but not ATP, depletion in 95% O2-mediated injury of preterm pneumocytes in vitro Arch. Biochem. Biophys. 313 1994 131 138
28. S.M. Deneke, B.A. Lynch, and B.L. Fanburg Transient depletion of lung glutathione by diethylmaleate enhances oxygen toxicity J. Appl. Physiol. 58 1985 571 574
29. J.D. Stenzel, S.E. Welty, A.E. Benzick, E.O. Smith, C.V. Smith, and T.N. Hansen Hyperoxic lung injury in Fischer-344 and Sprague-Dawley rats in vivo Free Radic. Biol. Med. 14 1993 531 539
30. H.S. Kim, Y. Manevich, S.I. Feinstein, J.H. Pak, Y.S. Ho, and A.B. Fisher Induction of 1-cys peroxiredoxin expression by oxidative stress in lung epithelial cells Am. J. Physiol. Lung Cell. Mol. Physiol. 285 2003 L363 L369
31. J.F. Dierick, F. Wenders, F. Chainiaux, J. Remacle, A.B. Fisher, and O. Toussaint Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB Biogerontology 4 2003 125 131
32. P.A. Dennery, D.R. Spitz, G. Yang, A. Tatarov, C.S. Lee, M.L. Shegog, and K.D. Poss Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2 J. Clin. Invest. 101 1998 1001 1011
33. H.J. Forman, E.I. Rotman, and A.B. Fisher Roles of selenium and sulfur-containing amino acids in protection against oxygen toxicity Lab. Invest. 49 1983 148 153
34. L. Zhao, H.P. Wang, H.J. Zhang, C.J. Weydert, F.E. Domann, L.W. Oberley, and G.R. Buettner L-PhGPx expression can be suppressed by antisense oligodeoxynucleotides Arch. Biochem. Biophys. 417 2003 212 218