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Volumn 24, Issue 9, 2008, Pages 379-382

Will new antischistosomal drugs finally emerge?

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMONY TARTRATE; ANTISCHISTOSOMAL AGENT; ARTEMISININ; AURANOFIN; FURAZOLIDONE; GLUTAREDOXIN; GLUTATHIONE; GLUTATHIONE REDUCTASE; OLTIPRAZ; OXADIAZOLE 2 OXIDE; OXADIAZOLE DERIVATIVE; PHOSPHINE DERIVATIVE; PHOSPHINIC AMIDE; PRAZIQUANTEL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOREDOXIN; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

EID: 49449093529     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2008.05.006     Document Type: Short Survey
Times cited : (61)

References (24)
  • 1
    • 0037847426 scopus 로고    scopus 로고
    • Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa
    • Van der Werf M.J., et al. Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa. Acta Trop. 86 (2003) 125-140
    • (2003) Acta Trop. , vol.86 , pp. 125-140
    • Van der Werf, M.J.1
  • 2
    • 1842634413 scopus 로고    scopus 로고
    • Progress in the prevention and control of schistosomiasis and soil-transmitted helminthiasis
    • Savioli L., et al. Progress in the prevention and control of schistosomiasis and soil-transmitted helminthiasis. Parasitol. Int. 53 (2004) 103-113
    • (2004) Parasitol. Int. , vol.53 , pp. 103-113
    • Savioli, L.1
  • 3
    • 35648935092 scopus 로고    scopus 로고
    • Recent progress in integrated neglected tropical disease control
    • Hotez P., et al. Recent progress in integrated neglected tropical disease control. Trends Parasitol. 23 (2007) 511-514
    • (2007) Trends Parasitol. , vol.23 , pp. 511-514
    • Hotez, P.1
  • 4
    • 18144419337 scopus 로고    scopus 로고
    • Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis
    • King C.H., et al. Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis. Lancet 365 (2005) 1561-1569
    • (2005) Lancet , vol.365 , pp. 1561-1569
    • King, C.H.1
  • 5
    • 48949118009 scopus 로고    scopus 로고
    • Decision-model estimation of the age-specific disability weight for schistosomiasis japonica: a systematic review of the literature
    • Finkelstein J.L., et al. Decision-model estimation of the age-specific disability weight for schistosomiasis japonica: a systematic review of the literature. PLoS Negl. Trop. Dis. 2 (2008) e158
    • (2008) PLoS Negl. Trop. Dis. , vol.2
    • Finkelstein, J.L.1
  • 6
    • 0028895250 scopus 로고
    • Antischistosomal drugs: past, present... and future?
    • Cioli D., et al. Antischistosomal drugs: past, present... and future?. Pharmacol. Ther. 68 (1995) 35-85
    • (1995) Pharmacol. Ther. , vol.68 , pp. 35-85
    • Cioli, D.1
  • 7
    • 0035217959 scopus 로고    scopus 로고
    • The potential of artemether for the control of schistosomiasis
    • Utzinger J., et al. The potential of artemether for the control of schistosomiasis. Int. J. Parasitol. 31 (2001) 1549-1562
    • (2001) Int. J. Parasitol. , vol.31 , pp. 1549-1562
    • Utzinger, J.1
  • 8
    • 41849098521 scopus 로고    scopus 로고
    • Identification of oxadiazoles as new drug leads for the control of schistosomiasis
    • Sayed A.A., et al. Identification of oxadiazoles as new drug leads for the control of schistosomiasis. Nat. Med. 14 (2008) 407-412
    • (2008) Nat. Med. , vol.14 , pp. 407-412
    • Sayed, A.A.1
  • 9
    • 0026587881 scopus 로고
    • Molecular cloning and sequencing of glutathione peroxidase from Schistosoma mansoni
    • Williams D.L., et al. Molecular cloning and sequencing of glutathione peroxidase from Schistosoma mansoni. Mol. Biochem. Parasitol. 52 (1992) 127-130
    • (1992) Mol. Biochem. Parasitol. , vol.52 , pp. 127-130
    • Williams, D.L.1
  • 10
    • 0028215866 scopus 로고
    • Cloning and characterization of the gene encoding Schistosoma mansoni glutathione peroxidase
    • Roche C., et al. Cloning and characterization of the gene encoding Schistosoma mansoni glutathione peroxidase. Gene 138 (1994) 149-152
    • (1994) Gene , vol.138 , pp. 149-152
    • Roche, C.1
  • 11
    • 0036710531 scopus 로고    scopus 로고
    • Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin
    • Alger H.M., et al. Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin. Int. J. Parasitol. 32 (2002) 1285-1289
    • (2002) Int. J. Parasitol. , vol.32 , pp. 1285-1289
    • Alger, H.M.1
  • 12
    • 0037197711 scopus 로고    scopus 로고
    • The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase
    • Alger H.M., and Williams D.L. The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase. Mol. Biochem. Parasitol. 121 (2002) 129-139
    • (2002) Mol. Biochem. Parasitol. , vol.121 , pp. 129-139
    • Alger, H.M.1    Williams, D.L.2
  • 13
    • 33745195480 scopus 로고    scopus 로고
    • Redox balance mechanisms in Schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets
    • Sayed A.A., et al. Redox balance mechanisms in Schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets. J. Biol. Chem. 281 (2006) 17001-17010
    • (2006) J. Biol. Chem. , vol.281 , pp. 17001-17010
    • Sayed, A.A.1
  • 14
    • 2942532835 scopus 로고    scopus 로고
    • Biochemical characterization of 2-Cys peroxiredoxins from Schistosoma mansoni
    • Sayed A.A., et al. Biochemical characterization of 2-Cys peroxiredoxins from Schistosoma mansoni. J. Biol. Chem. 279 (2004) 26159-26166
    • (2004) J. Biol. Chem. , vol.279 , pp. 26159-26166
    • Sayed, A.A.1
  • 15
    • 2942574588 scopus 로고    scopus 로고
    • Linked thioredoxin-glutathione systems in platyhelminths
    • Salinas G., et al. Linked thioredoxin-glutathione systems in platyhelminths. Trends Parasitol. 20 (2004) 340-346
    • (2004) Trends Parasitol. , vol.20 , pp. 340-346
    • Salinas, G.1
  • 16
    • 0035957325 scopus 로고    scopus 로고
    • Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems
    • Sun Q.A., et al. Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 3673-3678
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 3673-3678
    • Sun, Q.A.1
  • 17
    • 0037631358 scopus 로고    scopus 로고
    • Alternative mRNAs arising from trans-splicing code for mitochondrial and cytosolic variants of Echinococcus granulosus thioredoxin glutathione reductase
    • Agorio A., et al. Alternative mRNAs arising from trans-splicing code for mitochondrial and cytosolic variants of Echinococcus granulosus thioredoxin glutathione reductase. J. Biol. Chem. 278 (2003) 12920-12928
    • (2003) J. Biol. Chem. , vol.278 , pp. 12920-12928
    • Agorio, A.1
  • 18
    • 0344665643 scopus 로고    scopus 로고
    • Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci)
    • Rendón J.L., et al. Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci). Mol. Biochem. Parasitol. 133 (2004) 61-69
    • (2004) Mol. Biochem. Parasitol. , vol.133 , pp. 61-69
    • Rendón, J.L.1
  • 19
    • 34347264532 scopus 로고    scopus 로고
    • Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target
    • Kuntz A.N., et al. Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target. PLoS Med. 4 (2007) e206
    • (2007) PLoS Med. , vol.4
    • Kuntz, A.N.1
  • 20
    • 48949117601 scopus 로고    scopus 로고
    • Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade
    • Simeonov A., et al. Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade. PLoS Negl. Trop. Dis. 2 (2008) e127
    • (2008) PLoS Negl. Trop. Dis. , vol.2
    • Simeonov, A.1
  • 21
    • 0024821351 scopus 로고
    • Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates
    • James S.L., and Glaven J. Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates. J. Immunol. 143 (1989) 4208-4212
    • (1989) J. Immunol. , vol.143 , pp. 4208-4212
    • James, S.L.1    Glaven, J.2
  • 22
    • 12344273021 scopus 로고    scopus 로고
    • Pharmacological properties of furoxans and benzofuroxans: recent developments
    • Cerecetto H., and Porcal W. Pharmacological properties of furoxans and benzofuroxans: recent developments. Mini Rev. Med. Chem. 5 (2005) 57-71
    • (2005) Mini Rev. Med. Chem. , vol.5 , pp. 57-71
    • Cerecetto, H.1    Porcal, W.2
  • 23
    • 47349121027 scopus 로고    scopus 로고
    • Glutathione reductase and thioredoxin reductase at the crossroads: the structure of Schistosoma mansoni thioredoxin glutathione reductase.
    • Angelucci F., et al. Glutathione reductase and thioredoxin reductase at the crossroads: the structure of Schistosoma mansoni thioredoxin glutathione reductase. Proteins 72 (2008) 936-945
    • (2008) Proteins , vol.72 , pp. 936-945
    • Angelucci, F.1
  • 24
    • 0842274205 scopus 로고    scopus 로고
    • Rediscovering the sweet spot in drug discovery
    • Brown D., and Superti-Furga G. Rediscovering the sweet spot in drug discovery. Drug Discov. Today 8 (2003) 1067-1077
    • (2003) Drug Discov. Today , vol.8 , pp. 1067-1077
    • Brown, D.1    Superti-Furga, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.