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Volumn 32, Issue 6, 2013, Pages 724-735

Peroxiredoxin 2 specifically regulates the oxidative and metabolic stress response of human metastatic breast cancer cells in lungs

Author keywords

angiogenesis; lung metastasis; metabolic stress; oxidative stress; peroxiredoxins

Indexed keywords

GLUCOSE; GREEN FLUORESCENT PROTEIN; HYDROGEN PEROXIDE; PEROXIREDOXIN 2; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA;

EID: 84873735490     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.93     Document Type: Article
Times cited : (82)

References (54)
  • 1
    • 65249178959 scopus 로고    scopus 로고
    • Translating the metastasis paradigm from scientific theory to clinical oncology
    • Dong F, Budhu AS, Wang XW. Translating the metastasis paradigm from scientific theory to clinical oncology. Clin Cancer Res 2009; 15: 2588-2593.
    • (2009) Clin Cancer Res , vol.15 , pp. 2588-2593
    • Dong, F.1    Budhu, A.S.2    Wang, X.W.3
  • 2
    • 0036990103 scopus 로고    scopus 로고
    • The organ microenvironment and cancer metastasis
    • Fidler IJ. The organ microenvironment and cancer metastasis. Differentiation 2002; 70: 498-505.
    • (2002) Differentiation , vol.70 , pp. 498-505
    • Fidler, I.J.1
  • 4
    • 34247269026 scopus 로고    scopus 로고
    • Genetic determinants of cancer metastasis
    • Nguyen DX, Massagué J. Genetic determinants of cancer metastasis. Nat Rev Genet 2007; 8: 341-352.
    • (2007) Nat Rev Genet , vol.8 , pp. 341-352
    • Nguyen, D.X.1    Massagué, J.2
  • 5
    • 27144488136 scopus 로고    scopus 로고
    • Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer
    • Weigelt B, Hu Z, He X, Livasy C, Carey LA, Ewend MG et al. Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer. Cancer Res 2005; 65: 9155-9158.
    • (2005) Cancer Res , vol.65 , pp. 9155-9158
    • Weigelt, B.1    Hu, Z.2    He, X.3    Livasy, C.4    Carey, L.A.5    Ewend, M.G.6
  • 9
    • 41149157649 scopus 로고    scopus 로고
    • TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4
    • Padua D, Zhang XH, Wang Q, Nadal C, Gerald WL, Gomis RR et al. TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 2008; 133: 66-77.
    • (2008) Cell , vol.133 , pp. 66-77
    • Padua, D.1    Zhang, X.H.2    Wang, Q.3    Nadal, C.4    Gerald, W.L.5    Gomis, R.R.6
  • 11
    • 26244466587 scopus 로고    scopus 로고
    • Bcl-x(L)-mediated changes in metabolic pathways of breast cancer cells: From survival in the blood stream to organ-specific metastasis
    • España L, Mart́n B, Aragüés R, Chiva C, Oliva B, Andreu D, et al. Bcl-x(L)-mediated changes in metabolic pathways of breast cancer cells: from survival in the blood stream to organ-specific metastasis, Am J Pathol, 2005, 167, 1125-1137
    • (2005) Am J Pathol , vol.167 , pp. 1125-1137
    • España, L.1    Mart́n, B.2    Aragüés, R.3    Chiva, C.4    Oliva, B.5    Andreu, D.6
  • 12
    • 0034674703 scopus 로고    scopus 로고
    • Role of peroxiredoxins in regulating intracellular hydrogen peroxide and hydrogen peroxide-induced apoptosis in thyroid cells
    • Kim H, Lee TH, Park ES, Suh JM, Park SJ, Chung HK et al. Role of peroxiredoxins in regulating intracellular hydrogen peroxide and hydrogen peroxide-induced apoptosis in thyroid cells. J Biol Chem 2000; 275: 18266-18270.
    • (2000) J Biol Chem , vol.275 , pp. 18266-18270
    • Kim, H.1    Lee, T.H.2    Park, E.S.3    Suh, J.M.4    Park, S.J.5    Chung, H.K.6
  • 13
    • 0030803669 scopus 로고    scopus 로고
    • The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
    • Wen ST, Van Etten RA. The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity. Genes Dev 1997; 11: 2456-2467.
    • (1997) Genes Dev , vol.11 , pp. 2456-2467
    • Wen, S.T.1    Van Etten, R.A.2
  • 14
    • 0037205455 scopus 로고    scopus 로고
    • Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site
    • Rabilloud T, Heller M, Gasnier F, Luche S, Rey C, Aebersold R et al. Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site. J Biol Chem 2002; 277: 19396-19401.
    • (2002) J Biol Chem , vol.277 , pp. 19396-19401
    • Rabilloud, T.1    Heller, M.2    Gasnier, F.3    Luche, S.4    Rey, C.5    Aebersold, R.6
  • 16
    • 0036287739 scopus 로고    scopus 로고
    • Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein
    • Fujii J, Ikeda Y. Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein. Redox Rep 2002; 7: 123-130.
    • (2002) Redox Rep , vol.7 , pp. 123-130
    • Fujii, J.1    Ikeda, Y.2
  • 17
    • 53049096831 scopus 로고    scopus 로고
    • Functional clustering of metastasis proteins describes plastic adaptation resources of breast-cancer cells to new microenvironments
    • Mart?́n B, Sanz R, Aragües R, Oliva B, Sierra A. Functional clustering of metastasis proteins describes plastic adaptation resources of breast-cancer cells to new microenvironments. J Proteome Res 2008; 7: 3242-3253.
    • (2008) J Proteome Res , vol.7 , pp. 3242-3253
    • Mart́n, B.1    Sanz, R.2    Aragües, R.3    Oliva, B.4    Sierra, A.5
  • 19
    • 20044390016 scopus 로고    scopus 로고
    • Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
    • Ungerstedt JS, Sowa Y, Xu WS, Shao Y, Dokmanovic M, Perez G et al. Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors. Proc Natl Acad Sci USA 2005; 102: 673-678.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 673-678
    • Ungerstedt, J.S.1    Sowa, Y.2    Xu, W.S.3    Shao, Y.4    Dokmanovic, M.5    Perez, G.6
  • 20
    • 0036395928 scopus 로고    scopus 로고
    • Macrophage signaling and respiratory burst
    • Iles KE, Forman HJ. Macrophage signaling and respiratory burst. Immunol Res 2002; 26: 95-105.
    • (2002) Immunol Res , vol.26 , pp. 95-105
    • Iles, K.E.1    Forman, H.J.2
  • 21
    • 84873741955 scopus 로고    scopus 로고
    • Gas transport between the lungs & the tissues
    • Weitz M, Brown RY (eds) Chapter 37, 22 edn. LANGE basic science, McGrow-Hill Companies, USA
    • Ganong WF. Gas transport between the lungs & the tissues. In: Weitz M, Brown RY (eds). Ganong's Review of Medical Physiology, Chapter 37, 22 edn. LANGE basic science, McGrow-Hill Companies, USA, 2005. pp 631-697.
    • (2005) Ganong's Review of Medical Physiology , pp. 631-697
    • Ganong, W.F.1
  • 22
    • 39149106144 scopus 로고    scopus 로고
    • Mitochondrial metabolism, redox signaling, and fusion: A mitochondria-ROS-HIF-1-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer
    • Archer S, Gomberg-Maitland M, Maitland M, Rich S, Garcia J, Weir K. Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1- Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am J Physiol Heart Circ Physiol 2008; 294: H570-H578.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Archer, S.1    Gomberg-Maitland, M.2    Maitland, M.3    Rich, S.4    Garcia, J.5    Weir, K.6
  • 23
    • 58149395029 scopus 로고    scopus 로고
    • A redox-sensitive peroxiredoxin that is important for longevity has tissue-and stress-specific roles in stress resistance
    • Oláhová M, Taylor SR, Khazaipoul S, Wang J, Morgan BA, Matsumoto K et al. A redox-sensitive peroxiredoxin that is important for longevity has tissue-and stress-specific roles in stress resistance. Proc Natl Acad Sci USA 2008; 105: 19839-19844.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19839-19844
    • Oláhová, M.1    Taylor, S.R.2    Khazaipoul, S.3    Wang, J.4    Morgan, B.A.5    Matsumoto, K.6
  • 24
    • 33947204162 scopus 로고    scopus 로고
    • Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte
    • Low FM, Hampton MB, Peskin AV. Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte. Blood 2007; 109: 2611-2617.
    • (2007) Blood , vol.109 , pp. 2611-2617
    • Low, F.M.1    Hampton, M.B.2    Peskin, A.V.3
  • 25
    • 67649391256 scopus 로고    scopus 로고
    • Novel protective mechanism against irreversible hyperoxidation of peroxiredoxin: Nalpha-terminal acetylation of human peroxiredoxin II
    • Seo JH, Lim JC, Lee DY. Novel protective mechanism against irreversible hyperoxidation of peroxiredoxin: Nalpha-terminal acetylation of human peroxiredoxin II. J Biol Chem 2009; 284: 13455-13465.
    • (2009) J Biol Chem , vol.284 , pp. 13455-13465
    • Seo, J.H.1    Lim, J.C.2    Lee, D.Y.3
  • 26
    • 33845543991 scopus 로고    scopus 로고
    • The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics
    • Tao M, Wang L, Wendt-Pienkowski E, George NP, Galm U, Zhang G et al. The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics. Mol Biosyst 2007; 3: 60-74.
    • (2007) Mol Biosyst , vol.3 , pp. 60-74
    • Tao, M.1    Wang, L.2    Wendt-Pienkowski, E.3    George, N.P.4    Galm, U.5    Zhang, G.6
  • 29
    • 20544449673 scopus 로고    scopus 로고
    • The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid-b. oxidation
    • Buzzai M, Bauer DE, Jones RG, DeBerardinis R, Hatzivassiliou G, Elstro RL et al. The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid-b.oxidation. Oncogene 2005; 24: 4165-4173.
    • (2005) Oncogene , vol.24 , pp. 4165-4173
    • Buzzai, M.1    Bauer, D.E.2    Jones, R.G.3    Deberardinis, R.4    Hatzivassiliou, G.5    Elstro, R.L.6
  • 30
    • 35548936968 scopus 로고    scopus 로고
    • A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
    • Jang Y, Sharkis S. A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 2007; 110: 3056-3063.
    • (2007) Blood , vol.110 , pp. 3056-3063
    • Jang, Y.1    Sharkis, S.2
  • 31
    • 77955449199 scopus 로고    scopus 로고
    • Proteomic analysis of interstitial fluid in bone marrow identified that peroxiredoxin 2 regulates H2O2 level of bone marrow during aging
    • Wang W, Gou L, Xie G, Tong A, He F, Lu Z et al. Proteomic analysis of interstitial fluid in bone marrow identified that peroxiredoxin 2 regulates H2O2 level of bone marrow during aging. J Proteome Res 2010; 9: 3812-3819.
    • (2010) J Proteome Res , vol.9 , pp. 3812-3819
    • Wang, W.1    Gou, L.2    Xie, G.3    Tong, A.4    He, F.5    Lu, Z.6
  • 33
    • 57449115616 scopus 로고    scopus 로고
    • Tumor metabolism: Cancer cells give and take lactate. Commentary
    • Semenza GL. Tumor metabolism: cancer cells give and take lactate. Commentary. J Clin Invest 2008; 118: 3835-3837.
    • (2008) J Clin Invest , vol.118 , pp. 3835-3837
    • Semenza, G.L.1
  • 34
    • 33846002728 scopus 로고    scopus 로고
    • A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
    • Bonnet S, Archer SL, Allalunis-Turner J, Haromy A, Beaulieu C, Thompson R et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell 2007; 11: 37-51.
    • (2007) Cancer Cell , vol.11 , pp. 37-51
    • Bonnet, S.1    Archer, S.L.2    Allalunis-Turner, J.3    Haromy, A.4    Beaulieu, C.5    Thompson, R.6
  • 35
  • 36
    • 67650456890 scopus 로고    scopus 로고
    • MDA-MB-435 and M14 cell lines: Identical but not M14 melanoma?
    • Chambers AF. MDA-MB-435 and M14 cell lines: identical but not M14 melanoma? Cancer Res 2009; 69: 5292-5293.
    • (2009) Cancer Res , vol.69 , pp. 5292-5293
    • Chambers, A.F.1
  • 37
    • 34548080939 scopus 로고    scopus 로고
    • Are peroxiredoxins tumor suppressors?
    • Neumann CA, Fang Q. Are peroxiredoxins tumor suppressors? Curr Opin Pharmacol 2007; 7: 375-380.
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 375-380
    • Neumann, C.A.1    Fang, Q.2
  • 38
    • 33750471197 scopus 로고    scopus 로고
    • Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: Molecular basis and biological significance
    • Bubici C, Papa S, Dean K, Franzoso G. Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance. Oncogene 2006; 25: 6731-6748.
    • (2006) Oncogene , vol.25 , pp. 6731-6748
    • Bubici, C.1    Papa, S.2    Dean, K.3    Franzoso, G.4
  • 40
    • 65249185741 scopus 로고    scopus 로고
    • Regulation of reactive oxygen species homeostasis by peroxiredoxins and c-Myc
    • Graves JA, Metukuri M, Scott D, Rothermund K, Prochownik EV. Regulation of reactive oxygen species homeostasis by peroxiredoxins and c-Myc. J Biol Chem 2009; 284: 6520-6529.
    • (2009) J Biol Chem , vol.284 , pp. 6520-6529
    • Graves, J.A.1    Metukuri, M.2    Scott, D.3    Rothermund, K.4    Prochownik, E.V.5
  • 41
    • 79953158615 scopus 로고    scopus 로고
    • Peroxiredoxin II restrains DNA damage-induced death in cancer cells by positively regulating JNK-dependent DNA repair
    • Lee KW, Lee DJ, Lee JY, Kang DH, Kwon J, Kang SW. Peroxiredoxin II restrains DNA damage-induced death in cancer cells by positively regulating JNK-dependent DNA repair. J Biol Chem 2011; 286: 8394-8404.
    • (2011) J Biol Chem , vol.286 , pp. 8394-8404
    • Lee, K.W.1    Lee, D.J.2    Lee, J.Y.3    Kang, D.H.4    Kwon, J.5    Kang, S.W.6
  • 42
    • 33749341200 scopus 로고    scopus 로고
    • Inhibitory effect of peroxiredoxin II (Prx II) on Ras-ERK-NFkappaB pathway in mouse embryonic fibroblast (MEF) senescence
    • Han YH, Kwon JH, Yu DY, Moon EY. Inhibitory effect of peroxiredoxin II (Prx II) on Ras-ERK-NFkappaB pathway in mouse embryonic fibroblast (MEF) senescence. Free Radic Res 2006; 40: 1182-1189.
    • (2006) Free Radic Res , vol.40 , pp. 1182-1189
    • Han, Y.H.1    Kwon, J.H.2    Yu, D.Y.3    Moon, E.Y.4
  • 43
    • 25444496950 scopus 로고    scopus 로고
    • Anti-apoptotic proteins induce non-random genetic alterations that result in selecting breast cancer metastatic cells
    • Méndez O, Fernández Y, Peinado MA, Moreno V, Sierra A. Anti-apoptotic proteins induce non-random genetic alterations that result in selecting breast cancer metastatic cells. Clin Exp Metastasis 2005; 22: 297-307.
    • (2005) Clin Exp Metastasis , vol.22 , pp. 297-307
    • Méndez, O.1    Fernández, Y.2    Peinado, M.A.3    Moreno, V.4    Sierra, A.5
  • 44
    • 0242412965 scopus 로고    scopus 로고
    • Angiostatin inhibits bone metastasis formation in nude mice through a direct anti-osteoclastic activity
    • Peyruchaud O, Serre CM, NicAmhlaoibh R, Fournier P, Clezardin P. Angiostatin inhibits bone metastasis formation in nude mice through a direct anti-osteoclastic activity. J Biol Chem 2003; 278: 45826-45832.
    • (2003) J Biol Chem , vol.278 , pp. 45826-45832
    • Peyruchaud, O.1    Serre, C.M.2    Nicamhlaoibh, R.3    Fournier, P.4    Clezardin, P.5
  • 45
    • 15244343497 scopus 로고    scopus 로고
    • Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer
    • Boucharaba A, Serre CM, Gres S, Saulnier-Blache JS, Bordet JC, Guglielmi J et al. Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer. J Clin Invest 2004; 114: 1714-1725.
    • (2004) J Clin Invest , vol.114 , pp. 1714-1725
    • Boucharaba, A.1    Serre, C.M.2    Gres, S.3    Saulnier-Blache, J.S.4    Bordet, J.C.5    Guglielmi, J.6
  • 46
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 47
    • 0031239737 scopus 로고    scopus 로고
    • Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion
    • Vanden Hoek TL, Li C, Shao Z, Schumacker PT, Becker LB. Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion. J Mol Cell Cardiol 1997; 29: 2571-2583.
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 2571-2583
    • Vanden Hoek, T.L.1    Li, C.2    Shao, Z.3    Schumacker, P.T.4    Becker, L.B.5
  • 48
    • 33947181890 scopus 로고    scopus 로고
    • Analysis of progenitor cell-scaffold combinations by in vivo non-invasive photonic imaging
    • Román I, Vilalta M, Rodriguez J, Matthies AM, Srouji S, Livne E et al. Analysis of progenitor cell-scaffold combinations by in vivo non-invasive photonic imaging. Biomaterials 2007; 28: 2718-2728.
    • (2007) Biomaterials , vol.28 , pp. 2718-2728
    • Román, I.1    Vilalta, M.2    Rodriguez, J.3    Matthies, A.M.4    Srouji, S.5    Livne, E.6
  • 49
    • 0026351389 scopus 로고
    • Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis
    • Zhang RD, Fidler IJ, Price JE. Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis. Invasion Metastasis 1991; 11: 204-215.
    • (1991) Invasion Metastasis , vol.11 , pp. 204-215
    • Zhang, R.D.1    Fidler, I.J.2    Price, J.E.3
  • 50
    • 0034783467 scopus 로고    scopus 로고
    • Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: Application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions
    • Peyruchaud O, Winding B, Pécheur I, Serre CM, Delmas P, Clézardin P. Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions. J Bone Miner Res 2001; 16: 2027-2034.
    • (2001) J Bone Miner Res , vol.16 , pp. 2027-2034
    • Peyruchaud, O.1    Winding, B.2    Pécheur, I.3    Serre, C.M.4    Delmas, P.5    Clézardin, P.6
  • 51
    • 0036676419 scopus 로고    scopus 로고
    • Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone
    • Pécheur I, Peyruchaud O, Serre CM, Guglielmi J, Voland C, Bourre F et al. Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone. FASEB J 2002; 16: 1266-1268.
    • (2002) FASEB J , vol.16 , pp. 1266-1268
    • Pécheur, I.1    Peyruchaud, O.2    Serre, C.M.3    Guglielmi, J.4    Voland, C.5    Bourre, F.6
  • 52
    • 12944281687 scopus 로고    scopus 로고
    • Different effect of paclitaxel on primary tumor mass, tumor cell contents, and metastases for four experimental human prostate tumors expressing luciferase
    • El Hilali N, Rubio N, Blanco J. Different effect of paclitaxel on primary tumor mass, tumor cell contents, and metastases for four experimental human prostate tumors expressing luciferase. Clin Cancer Res 2005; 11: 1253-1258.
    • (2005) Clin Cancer Res , vol.11 , pp. 1253-1258
    • El Hilali, N.1    Rubio, N.2    Blanco, J.3
  • 54
    • 70149113077 scopus 로고    scopus 로고
    • R Development Core Team Foundation for Statistical Computing: Vienna, Austria
    • R Development Core Team R. A Language and Environment for Statistical Computing. Foundation for Statistical Computing: Vienna, Austria, 2009.
    • (2009) R. A Language and Environment for Statistical Computing


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