Deconstructing the catalytic efficiency of peroxiredoxin-5 peroxidatic cysteine

Biochemistry

Volumn 53, Issue 38, 2014, Pages 6113-6125

  Portillo Ledesma, Stephanie ^a   Sardi, Florencia ^a,b   Manta, Bruno ^b   Tourn, María Victoria ^a   Clippe, André ^c   Knoops, Bernard ^c   Alvarez, Beatriz ^a   Coitiño, E Laura ^a   Ferrer Sueta, Gerardo ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; HYDROGEN BONDS; MOLECULAR MODELING; PROTEINS; QUANTUM THEORY; RATE CONSTANTS;

B3LYP DENSITY FUNCTIONAL; CATALYTIC EFFICIENCIES; CONSERVED RESIDUES; LOW MOLECULAR WEIGHT; PEROXIDATIC CYSTEINE; QUANTUM MECHANICS/MOLECULAR MECHANICS; SPECIFIC REACTIVITY; TEMPORAL SEQUENCES;

SUBSTRATES;

BACTERIAL ENZYME; CYSTEINE DERIVATIVE; CYSTEINE ETHYL ESTER; ELECTROPHILE; HYDROGEN PEROXIDE; PEROXIREDOXIN 5; CYSTEINE; PEROXIREDOXIN; PRDX5 PROTEIN, HUMAN;

AEROPYRUM PERNIX; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DIELECTRIC CONSTANT; ENZYME ACTIVE SITE; ENZYME BINDING; HYDROGEN BOND; IONIC STRENGTH; MOLECULAR MECHANICS; MOLECULAR WEIGHT; NONHUMAN; NUCLEOPHILICITY; NUCLEOTIDE SEQUENCE; PH; PH MEASUREMENT; QUANTUM MECHANICS; STATIC ELECTRICITY; SUBSTITUTION REACTION; SUBURETHRAL SLING; WILD TYPE; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; METABOLISM; PROTEIN CONFORMATION;

CATALYTIC DOMAIN; CYSTEINE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; MODELS, MOLECULAR; PEROXIREDOXINS; PROTEIN CONFORMATION;

EID: 84907518566     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500389m     Document Type: Article

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