Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression

Free Radical Biology and Medicine

Volumn 53, Issue 3, 2012, Pages 447-456

  Jeong, Woojin ^a   Bae, Soo Han ^a   Toledano, Michel B ^b   Rhee, Sue Goo ^a  

^a Ewha Womans University   (South Korea)

^b SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

Author keywords

AP 1; Cysteine hyperoxidation; Free radicals; Lipopolysaccharide; Nrf2; Peroxiredoxin; Sulfiredoxin; Toll like receptor 4

Indexed keywords

CIGARETTE SMOKE; CYCLIC AMP; GLUTATHIONE DERIVATIVE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID; PEROXIREDOXIN; PROTEASOME; PROTEIN C JUN; SULFINIC ACID DERIVATIVE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR YAP1; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN;

ENZYME REGULATION; EPITHELIUM CELL; GRAM NEGATIVE BACTERIUM; HUMAN; IMMUNOSTIMULATION; MACROPHAGE; MAMMAL CELL; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; REVIEW; SACCHAROMYCES CEREVISIAE; SEPTIC SHOCK; SKIN CARCINOGENESIS;

ANIMALS; BASE SEQUENCE; GENE EXPRESSION REGULATION; GLUTATHIONE; HUMANS; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXIDOREDUCTASES ACTING ON SULFUR GROUP DONORS; PEROXIREDOXINS; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTOR AP-1;

ANIMALIA; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 84863463209     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.05.020     Document Type: Review

References (115)

1. B. Biteau, J. Labarre, and M.B. Toledano ATP-dependent reduction of cysteine-sulphinic acid by S. cerevisiae sulphiredoxin Nature 425 2003 980 984 (Pubitemid 37376931)
2. M.K. Kwak, N. Wakabayashi, K. Itoh, H. Motohashi, M. Yamamoto, and T.W. Kensler Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway: identification of novel gene clusters for cell survival J. Biol. Chem. 278 2003 8135 8145 (Pubitemid 36800555)
3. H.A. Woo, S.H. Bae, S. Park, and S.G. Rhee Sestrin 2 is not a reductase for cysteine sulfinic acid of peroxiredoxins Antioxid. Redox Signaling 11 2009 739 745
4. V.J. Findlay, D.M. Townsend, T.E. Morris, J.P. Fraser, L. He, and K.D. Tew A novel role for human sulfiredoxin in the reversal of glutathionylation Cancer Res. 66 2006 6800 6806 (Pubitemid 44085640)
5. M.B. Pascual, A. Mata-Cabana, F.J. Florencio, M. Lindahl, and F.J. Cejudo Overoxidation of 2-Cys peroxiredoxin in prokaryotes: cyanobacterial 2-Cys peroxiredoxins sensitive to oxidative stress J. Biol. Chem. 285 2010 34485 34492
6. M.K. Basu, and E.V. Koonin Evolution of eukaryotic cysteine sulfinic acid reductase, sulfiredoxin (Srx), from bacterial chromosome partitioning protein ParB Cell Cycle 4 2005 947 952 (Pubitemid 41359762)
7. F.X. Soriano, P. Baxter, L.M. Murray, M.B. Sporn, T.H. Gillingwater, and G.E. Hardingham Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin Mol. Cells 27 2009 279 282
8. S.G. Rhee, H.Z. Chae, and K. Kim Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling Free Radic. Biol. Med. 38 2005 1543 1552 (Pubitemid 40726061)
9. S.G. Rhee, and H.A. Woo Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger HO, and protein chaperones Antioxid. Redox Signaling 15 2011 781 794
10. A. Hall, K. Nelson, L.B. Poole, and P.A. Karplus Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins Antioxid. Redox Signaling 15 2011 795 815
11. 2 mixed-function oxidation system J. Biol. Chem. 263 1988 4704 4711
12. H.Z. Chae, S.J. Chung, and S.G. Rhee Thioredoxin-dependent peroxide reductase from yeast J. Biol. Chem. 269 1994 27670 27678 (Pubitemid 24346604)
13. H.Z. Chae, K. Robison, L.B. Poole, G. Church, G. Storz, and S.G. Rhee Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes Proc. Natl. Acad. Sci. USA 91 1994 7017 7021 (Pubitemid 24226793)
14. R. Bryk, P. Griffin, and C. Nathan Peroxynitrite reductase activity of bacterial peroxiredoxins Nature 407 2000 211 215
15. Z.A. Wood, E. Schroder, J. Robin Harris, and L.B. Poole Structure, mechanism and regulation of peroxiredoxins Trends Biochem. Sci. 28 2003 32 40 (Pubitemid 36051004)
16. S.G. Rhee, H.A. Woo, I.S. Kil, and S.H. Bae Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides J. Biol. Chem. 287 2012 4403 4410
17. Z.A. Wood, L.B. Poole, and P.A. Karplus Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling Science 300 2003 650 653 (Pubitemid 36520591)
18. T. Rabilloud, M. Heller, F. Gasnier, S. Luche, C. Rey, R. Aebersold, M. Benahmed, P. Louisot, and J. Lunardi Proteomics analysis of cellular response to oxidative stress: evidence for in vivo overoxidation of peroxiredoxins at their active site J. Biol. Chem. 277 2002 19396 19401 (Pubitemid 34967447)
19. H.A. Woo, H.Z. Chae, S.C. Hwang, K.S. Yang, S.W. Kang, K. Kim, and S.G. Rhee Reversing the inactivation of peroxiredoxins caused by cysteine sulfinic acid formation Science 300 2003 653 656 (Pubitemid 36520592)
20. M.S. Seo, S.W. Kang, K. Kim, I.C. Baines, T.H. Lee, and S.G. Rhee Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate J. Biol. Chem. 275 2000 20346 20354 (Pubitemid 30457609)
21. B. Knoops, J. Goemaere, V. Van der Eecken, and J.P. Declercq Peroxiredoxin 5: structure, mechanism, and function of the mammalian atypical 2-Cys peroxiredoxin Antioxid. Redox Signaling 15 2011 817 829
22. A.B. Fisher Peroxiredoxin 6: a bifunctional enzyme with glutathione peroxidase and phospholipase A activities Antioxid. Redox Signaling 15 2011 831 844
23. H.A. Woo, S.W. Kang, H.K. Kim, K.S. Yang, H.Z. Chae, and S.G. Rhee Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid: immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence J. Biol. Chem. 278 2003 47361 47364 (Pubitemid 37523174)
24. T.S. Chang, W. Jeong, H.A. Woo, S.M. Lee, S. Park, and S.G. Rhee Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine J. Biol. Chem. 279 2004 50994 51001 (Pubitemid 40017840)
25. S.G. Rhee, W. Jeong, T.S. Chang, and H.A. Woo Sulfiredoxin, the cysteine sulfinic acid reductase specific to 2-Cys peroxiredoxin: its discovery, mechanism of action, and biological significance Kidney Int. Suppl. 106 2007 S3 S8
26. H.A. Woo, W. Jeong, T.S. Chang, K.J. Park, S.J. Park, J.S. Yang, and S.G. Rhee Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins J. Biol. Chem. 280 2005 3125 3128 (Pubitemid 40223772)
27. W. Jeong, S.J. Park, T.S. Chang, D.Y. Lee, and S.G. Rhee Molecular mechanism of the reduction of cysteine sulfinic acid of peroxiredoxin to cysteine by mammalian sulfiredoxin J. Biol. Chem. 281 2006 14400 14407 (Pubitemid 43848370)
28. T.J. Jonsson, M.S. Murray, L.C. Johnson, and W.T. Lowther Reduction of cysteine sulfinic acid in peroxiredoxin by sulfiredoxin proceeds directly through a sulfinic phosphoryl ester intermediate J. Biol. Chem. 283 2008 23846 23851
29. T.J. Jonsson, A.W. Tsang, W.T. Lowther, and C.M. Furdui Identification of intact protein thiosulfinate intermediate in the reduction of cysteine sulfinic acid in peroxiredoxin by human sulfiredoxin J. Biol. Chem. 283 2008 22890 22894
30. X. Roussel, G. Bechade, A. Kriznik, A. Van Dorsselaer, S. Sanglier-Cianferani, G. Branlant, and S. Rahuel-Clermont Evidence for the formation of a covalent thiosulfinate intermediate with peroxiredoxin in the catalytic mechanism of sulfiredoxin J. Biol. Chem. 283 2008 22371 22382
31. 2, a necessary evil for cell signaling Science 312 2006 1882 1883 (Pubitemid 43993698)
32. C.C. Winterbourn Reconciling the chemistry and biology of reactive oxygen species Nat. Chem. Biol. 4 2008 278 286 (Pubitemid 351550893)
33. H.Z. Chae, H.J. Kim, S.W. Kang, and S.G. Rhee Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin Diabetes Res. Clin. Pract. 45 1999 101 112 (Pubitemid 29457756)
34. H.H. Jang, K.O. Lee, Y.H. Chi, B.G. Jung, S.K. Park, J.H. Park, J.R. Lee, S.S. Lee, J.C. Moon, J.W. Yun, Y.O. Choi, W.Y. Kim, J.S. Kang, G.W. Cheong, D.J. Yun, S.G. Rhee, M.J. Cho, and S.Y. Lee Two enzymes in one; two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function Cell 117 2004 625 635 (Pubitemid 38692528)
35. 2-induced cell death J. Biol. Chem. 280 2005 28775 28784 (Pubitemid 41105779)
36. C.A. Chrestensen, D.W. Starke, and J.J. Mieyal Acute cadmium exposure inactivates thioltransferase (glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis J. Biol. Chem. 275 2000 26556 26565
37. M. Fratelli, H. Demol, M. Puype, S. Casagrande, P. Villa, I. Eberini, J. Vandekerckhove, E. Gianazza, and P. Ghezzi Identification of proteins undergoing glutathionylation in oxidatively stressed hepatocytes and hepatoma cells Proteomics 3 2003 1154 1161 (Pubitemid 36929537)
38. J.W. Park, J.J. Mieyal, S.G. Rhee, and P.B. Chock Deglutathionylation of 2-Cys peroxiredoxin is specifically catalyzed by sulfiredoxin J. Biol. Chem. 284 2009 23364 23374
39. T. Matsumura, K. Okamoto, S. Iwahara, H. Hori, Y. Takahashi, T. Nishino, and Y. Abe Dimer-oligomer interconversion of wild-type and mutant rat 2-Cys peroxiredoxin: disulfide formation at dimer-dimer interfaces is not essential for decamerization J. Biol. Chem. 283 2008 284 293
40. A. Morinaka, Y. Funato, K. Uesugi, and H. Miki Oligomeric peroxiredoxin-I is an essential intermediate for p53 to activate MST1 kinase and apoptosis Oncogene 30 2011 4208 4218
41. Q. Wei, H. Jiang, C.P. Matthews, and N.H. Colburn Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies Proc. Natl. Acad. Sci. USA 105 2008 19738 19743
42. H. Kim, Y. Jung, B.S. Shin, H. Song, S.H. Bae, S.G. Rhee, and W. Jeong Redox regulation of lipopolysaccharide-mediated sulfiredoxin induction, which depends on both AP-1 and Nrf2 J. Biol. Chem. 285 2010 34419 34428
43. A. Bast, K. Fischer, S.F. Erttmann, and R. Walther Induction of peroxiredoxin I gene expression by LPS involves the Src/PI3K/JNK signalling pathway Biochim. Biophys. Acta 402-410 1799 2010
44. E. Shaulian, and M. Karin AP-1 as a regulator of cell life and death Nat. Cell Biol. 4 2002 E131 E136
45. D.A. Glauser, T. Brun, B.R. Gauthier, and W. Schlegel Transcriptional response of pancreatic beta cells to metabolic stimulation: large scale identification of immediate-early and secondary response genes BMC Mol. Biol. 8 2007 54
46. S. Papadia, F.X. Soriano, F. Leveille, M.A. Martel, K.A. Dakin, H.H. Hansen, A. Kaindl, M. Sifringer, J. Fowler, V. Stefovska, G. McKenzie, M. Craigon, R. Corriveau, P. Ghazal, K. Horsburgh, B.A. Yankner, D.J. Wyllie, C. Ikonomidou, and G.E. Hardingham Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses Nat. Neurosci. 11 2008 476 487 (Pubitemid 351441886)
47. S. Nagashima, T. Fukuda, Y. Kubota, A. Sugiura, M. Nakao, and R. Inatome Yanagi, S. CRMP5-associated GTPase (CRAG) protein protects neuronal cells against cytotoxicity of expanded polyglutamine protein partially via c-Fos-dependent activator protein-1 activation J. Biol. Chem. 286 2011 33879 33889
48. C.P. Matthews, A.M. Birkholz, A.R. Baker, C.M. Perella, G.R. Beck Jr, M.R. Young, and N.H. Colburn Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis Cancer Res. 67 2007 2430 2438 (Pubitemid 46548927)
49. Y.S. Kim, H.L. Lee, K.B. Lee, J.H. Park, W.Y. Chung, K.S. Lee, S.S. Sheen, K.J. Park, and S.C. Hwang Nuclear factor E2-related factor 2 dependent overexpression of sulfiredoxin and peroxiredoxin III in human lung cancer Korean J. Intern. Med. 26 2011 304 313
50. Q. Wei, H. Jiang, Z. Xiao, A. Baker, M.R. Young, T.D. Veenstra, and N.H. Colburn Sulfiredoxin-peroxiredoxin IV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling Proc. Natl. Acad. Sci. USA 108 2011 7004 7009
51. F.X. Soriano, S. Papadia, K.F. Bell, and G.E. Hardingham Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2 Epigenetics 4 2009 152 158
52. Q. Qin, R. Inatome, A. Hotta, M. Kojima, H. Yamamura, H. Hirai, T. Yoshizawa, H. Tanaka, K. Fukami, and S. Yanagi A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein J. Cell Biol. 172 2006 497 504 (Pubitemid 43243871)
53. D.C. Rubinsztein, and J. Carmichael Huntington's disease: molecular basis of neurodegeneration Expert Rev. Mol. Med. 5 2003 1 21
54. T.W. Kensler, and N. Wakabayashi Nrf2: friend or foe for chemoprevention? Carcinogenesis 31 2010 90 99
55. K. Itoh, J. Mimura, and M. Yamamoto Discovery of the negative regulator of Nrf2, Keap1: a historical overview Antioxid. Redox Signaling 13 2010 1665 1678
56. D.D. Zhang The Nrf2-Keap1-ARE signaling pathway: the regulation and dual function of Nrf2 in cancer Antioxid. Redox Signaling 13 2010 1623 1626
57. T. Nguyen, P. Nioi, and C.B. Pickett The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress J. Biol. Chem. 284 2009 13291 13295
58. T. Rangasamy, C.Y. Cho, R.K. Thimmulappa, L. Zhen, S.S. Srisuma, T.W. Kensler, M. Yamamoto, I. Petrache, R.M. Tuder, and S. Biswal Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice J. Clin. Invest. 114 2004 1248 1259 (Pubitemid 40385296)
59. F.X. Soriano, F. Leveille, S. Papadia, L.G. Higgins, J. Varley, P. Baxter, J.D. Hayes, and G.E. Hardingham Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione J. Neurochem. 107 2008 533 543
60. A. Singh, G. Ling, A.N. Suhasini, P. Zhang, M. Yamamoto, A. Navas-Acien, G. Cosgrove, R.M. Tuder, T.W. Kensler, W.H. Watson, and S. Biswal Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs Free Radic. Biol. Med. 46 2009 376 386
61. C.M. Cabello, W.B. Bair 3rd, S.D. Lamore, S. Ley, A.S. Bause, S. Azimian, and G.T. Wondrak The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth Free Radic. Biol. Med. 46 2009 220 231
62. W.W. Wasserman, and W.E. Fahl Functional antioxidant responsive elements Proc. Natl. Acad. Sci. USA 94 1997 5361 5366 (Pubitemid 27214788)
63. P. Nioi, M. McMahon, K. Itoh, M. Yamamoto, and J.D. Hayes Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence Biochem. J 374 2003 337 348 (Pubitemid 37094093)
64. S.H. Bae, S.H. Sung, E.J. Cho, S.K. Lee, H.E. Lee, H.A. Woo, D.Y. Yu, I.S. Kil, and S.G. Rhee Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver Hepatology 53 2011 945 953
65. S.H. Bae, H.A. Woo, S.H. Sung, H.E. Lee, S.K. Lee, I.S. Kil, and S.G. Rhee Induction of sulfiredoxin via an Nrf2-dependent pathway and hyperoxidation of peroxiredoxin III in the lungs of mice exposed to hyperoxia Antioxid. Redox Signaling 11 2009 937 948
66. I. Kessova, and A.I. Cederbaum CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury Curr. Mol. Med. 3 2003 509 518 (Pubitemid 37168595)
67. R.J. Ulevitch, and P.S. Tobias Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin Annu. Rev. Immunol. 13 1995 437 457
68. S. Akira, S. Uematsu, and O. Takeuchi Pathogen recognition and innate immunity Cell 124 2006 783 801 (Pubitemid 43261452)
69. K. Takeda, T. Kaisho, and S. Akira Toll-like receptors Annu. Rev. Immunol. 21 2003 335 376 (Pubitemid 37174535)
70. T. Kawai, and S. Akira TLR signaling Cell Death Differ. 13 2006 816 825
71. C. Wang, L. Deng, M. Hong, G.R. Akkaraju, J. Inoue, and Z.J. Chen TAK1 is a ubiquitin-dependent kinase of MKK and IKK Nature 412 2001 346 351 (Pubitemid 32694385)
72. Q. Huang, J. Yang, Y. Lin, C. Walker, J. Cheng, Z.G. Liu, and B. Su Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3 Nat. Immunol. 5 2004 98 103 (Pubitemid 38081474)
73. A. Matsuzawa, K. Saegusa, T. Noguchi, C. Sadamitsu, H. Nishitoh, S. Nagai, S. Koyasu, K. Matsumoto, K. Takeda, and H. Ichijo ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity Nat. Immunol. 6 2005 587 592 (Pubitemid 41710729)
74. Q.W. Xie, Y. Kashiwabara, and C. Nathan Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase J. Biol. Chem. 269 1994 4705 4708 (Pubitemid 24239438)
75. J.R. Delaney, and M. Mlodzik TGF-beta activated kinase-1: new insights into the diverse roles of TAK1 in development and immunity Cell Cycle 5 2006 2852 2855 (Pubitemid 44953934)
76. Q.W. Xie, R. Whisnant, and C. Nathan Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide J. Exp. Med 177 1993 1779 1784 (Pubitemid 23146145)
77. K.R. Morris, R.D. Lutz, H.S. Choi, T. Kamitani, K. Chmura, and E.D. Chan Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide Infect. Immun. 71 2003 1442 1452 (Pubitemid 36254331)
78. C.J. Lowenstein, C.S. Glatt, D.S. Bredt, and S.H. Snyder Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme Proc. Natl. Acad. Sci. USA 89 1992 6711 6715
79. A. Diet, K. Abbas, C. Bouton, B. Guillon, F. Tomasello, S. Fourquet, M.B. Toledano, and J.C. Drapier Regulation of peroxiredoxins by nitric oxide in immunostimulated macrophages J. Biol. Chem. 282 2007 36199 36205
80. K. Abbas, J. Breton, A.G. Planson, C. Bouton, J. Bignon, C. Seguin, S. Riquier, M.B. Toledano, and J.C. Drapier Nitric oxide activates an Nrf2/sulfiredoxin antioxidant pathway in macrophages Free Radic. Biol. Med. 51 2011 107 114
81. C.Q. Li, M.Y. Kim, L.C. Godoy, A. Thiantanawat, L.J. Trudel, and G.N. Wogan Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells Proc. Natl. Acad. Sci. USA 106 2009 14547 14551
82. S. Dhakshinamoorthy, and A.G. Porter Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells J. Biol. Chem 279 2004 20096 20107 (Pubitemid 38623454)
83. 2 involves KEAP1 disulfide formation J. Biol. Chem. 285 2010 8463 8471
84. J. MacMicking, Q.W. Xie, and C. Nathan Nitric oxide and macrophage function Annu. Rev. Immunol. 15 1997 323 350 (Pubitemid 27169284)
85. B. D'Autreaux, D. Touati, B. Bersch, J.M. Latour, and I. Michaud-Soret Direct inhibition by nitric oxide of the transcriptional ferric uptake regulation protein via nitrosylation of the iron Proc. Natl. Acad. Sci. USA 99 2002 16619 16624 (Pubitemid 36034022)
86. K.E. Iles, and H.J. Forman Macrophage signaling and respiratory burst Immunol. Res. 26 2002 95 105 (Pubitemid 35177488)
87. C.F. Nathan, and J.B. Hibbs Jr. Role of nitric oxide synthesis in macrophage antimicrobial activity Curr. Opin. Immunol. 3 1991 65 70
88. A.G. Planson, G. Palais, K. Abbas, M. Gerard, L. Couvelard, A. Delaunay, S. Baulande, J.C. Drapier, and M.B. Toledano Sulfiredoxin protects mice from lipopolysaccharide-induced endotoxic shock Antioxid. Redox Signaling 14 2011 2071 2080
89. H. Yang, N. Magilnick, C. Lee, D. Kalmaz, X. Ou, J.Y. Chan, and S.C. Lu Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1 Mol. Cell. Biol. 25 2005 5933 5946 (Pubitemid 40949988)
90. E.D. Owuor, and A.N. Kong Antioxidants and oxidants regulated signal transduction pathways Biochem. Pharmacol. 64 2002 765 770 (Pubitemid 35238028)
91. R. Vari, M. D'Archivio, C. Filesi, S. Carotenuto, B. Scazzocchio, C. Santangelo, C. Giovannini, and R. Masella Protocatechuic acid induces antioxidant/detoxifying enzyme expression through JNK-mediated Nrf2 activation in murine macrophages J. Nutr. Biochem. 22 2011 409 417
92. N.K. Lee, Y.G. Choi, J.Y. Baik, S.Y. Han, D.W. Jeong, Y.S. Bae, N. Kim, and S.Y. Lee A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation Blood 106 2005 852 859 (Pubitemid 41076424)
93. A. Singh, K.A. Zarember, D.B. Kuhns, and J.I. Gallin Impaired priming and activation of the neutrophil NADPH oxidase in patients with IRAK4 or NEMO deficiency J. Immunol. 182 2009 6410 6417
94. Y.S. Bae, J.H. Lee, S.H. Choi, S. Kim, F. Almazan, J.L. Witztum, and Y.I. Miller Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2 Circ. Res. 104 2009 210 218
95. A.T. Dinkova-Kostova, W.D. Holtzclaw, R.N. Cole, K. Itoh, N. Wakabayashi, Y. Katoh, M. Yamamoto, and P. Talalay Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Proc. Natl. Acad. Sci. USA 99 2002 11908 11913 (Pubitemid 34994497)
96. N. Wakabayashi, A.T. Dinkova-Kostova, W.D. Holtzclaw, M.I. Kang, A. Kobayashi, M. Yamamoto, T.W. Kensler, and P. Talalay Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers Proc. Natl. Acad. Sci. USA 101 2004 2040 2045 (Pubitemid 38229011)
97. C. Abate, L. Patel, F.J. Rauscher, and T. Curran Redox regulation of fos and jun DNA-binding activity in vitro Science 249 1990 1157 1161
98. S. Xanthoudakis, and T. Curran Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity EMBO J 11 1992 653 665
99. W.M. Toone, B.A. Morgan, and N. Jones Redox control of AP-1-like factors in yeast and beyond Oncogene 20 2001 2336 2346 (Pubitemid 32531293)
100. S. Wu, J. Gao, C. Ohlemeyer, D. Roos, H. Niessen, E. Kottgen, and R. Gessner Activation of AP-1 through reactive oxygen species by angiotensin II in rat cardiomyocytes Free Radic. Biol. Med. 39 2005 1601 1610 (Pubitemid 41642591)
101. S.R. Lee, K.S. Kwon, S.R. Kim, and S.G. Rhee Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor J. Biol. Chem. 273 1998 15366 15372 (Pubitemid 28298140)
102. H. Kamata, S. Honda, S. Maeda, L. Chang, H. Hirata, and M. Karin Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases Cell 120 2005 649 661 (Pubitemid 40343077)
103. M. Saitoh, H. Nishitoh, M. Fujii, K. Takeda, K. Tobiume, Y. Sawada, M. Kawabata, K. Miyazono, and H. Ichijo Mammalian thioredoxin is a direct inhibitor of apoptosis signal- regulating kinase (ASK) 1 EMBO J 17 1998 2596 2606 (Pubitemid 28221195)
104. K. Tobiume, M. Saitoh, and H. Ichijo Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer J. Cell. Physiol 191 2002 95 104 (Pubitemid 34195221)
105. 2-terminal kinase activation and apoptosis Mol. Biol. Cell 18 2007 3903 3913 (Pubitemid 47519483)
106. M.K. McElwee, M.O. Song, and J.H. Freedman Copper activation of NF-kappaB signaling in HepG2 cells J. Mol. Biol. 393 2009 1013 1021
107. J. Lee, C. Godon, G. Lagniel, D. Spector, J. Garin, J. Labarre, and M.B. Toledano Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast J. Biol. Chem. 274 1999 16040 16046
108. D.E. Fomenko, A. Koc, N. Agisheva, M. Jacobsen, A. Kaya, M. Malinouski, J.C. Rutherford, K.L. Siu, D.Y. Jin, D.R. Winge, and V.N. Gladyshev Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide Proc. Natl. Acad. Sci. USA 108 2011 2729 2734
109. B.A. Morgan, N. Bouquin, G.F. Merrill, and L.H. Johnston A yeast transcription factor bypassing the requirement for SBF and DSC1/MBF in budding yeast has homology to bacterial signal transduction proteins EMBO J 14 1995 5679 5689
110. 2 resistance elicited by caloric restriction require the peroxiredoxin Tsa1 in Saccharomyces cerevisiae Mol. Cell 43 2011 823 833
111. S. Zaman, S.I. Lippman, X. Zhao, and J.R. Broach How Saccharomyces responds to nutrients Annu. Rev. Genet. 42 2008 27 81
112. R.S. Sohal, and R. Weindruch Oxidative stress, caloric restriction, and aging Science 273 1996 59 63 (Pubitemid 26255420)
113. R.L. Levine Carbonyl modified proteins in cellular regulation, aging, and disease Free Radic. Biol. Med. 32 2002 790 796 (Pubitemid 34439249)
114. L.C. Enns, J.F. Morton, P.R. Treuting, M.J. Emond, N.S. Wolf, D.F. Dai, G.S. McKnight, P.S. Rabinovitch, and W.C. Ladiges Disruption of protein kinase A in mice enhances healthy aging PLoS One 4 2009 e5963
115. A.G. Hinnebusch Translational regulation of GCN4 and the general amino acid control of yeast Annu. Rev. Microbiol 59 2005 407 450 (Pubitemid 41507438)