Peroxiredoxin 3 is a key molecule regulating adipocyte oxidative stress, mitochondrial biogenesis, and adipokine expression

Antioxidants and Redox Signaling

Volumn 16, Issue 3, 2012, Pages 229-243

  Huh, Joo Young ^a   Kim, Yunghee ^a   Jeong, Jaeho ^a   Park, Jehyun ^a   Kim, Inok ^a   Huh, Kyu Ha ^b   Kim, Yu Seun ^b   Woo, Hyun Ae ^a   Rhee, Sue Goo ^a   Lee, Kong Joo ^a   Ha, Hunjoo ^a  

^a Ewha Womans University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; PEROXIREDOXIN 3; SUPEROXIDE;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HUMAN; INFLAMMATION; INSULIN RESISTANCE; KNOCKOUT MOUSE; LIPID METABOLISM; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; OXIDATION REDUCTION REACTION; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; PROTEOMICS; REGULATORY MECHANISM; WILD TYPE;

ADIPOCYTES; ADIPOGENESIS; ADIPOKINES; ADIPOSE TISSUE, WHITE; ADIPOSITY; ANIMALS; BLOOD GLUCOSE; CELL ENLARGEMENT; CELLS, CULTURED; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; LIPID METABOLISM; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; PEROXIREDOXIN III; PEROXIREDOXINS;

EID: 83255184392     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2010.3766     Document Type: Article

References (42)

1. Adachi J, Kumar C, Zhang Y, and Mann M. In-depth analysis of the adipocyte proteome by mass spectrometry and bioinformatics. Mol Cell Proteomics 6: 1257-1273, 2007. (Pubitemid 47099234)
2. Atiar Rahman M, Kumar SG, Lee SH, Hwang HS, Kim HA, and Yun JW. Proteome analysis for 3T3-L1 adipocyte differentiation. J Microbiol Biotechnol 18: 1895-1902, 2008.
3. Bays H, Mandarino L, and DeFronzo RA. Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: Peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. J Clin Endocrinol Metab 89: 463-478, 2004. (Pubitemid 38269844)
4. Chang TS, Cho CS, Park S, Yu S, Kang SW, and Rhee SG. Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria. J Biol Chem 279: 41975-41984, 2004. (Pubitemid 39313648)
5. Chascione C, Elwyn DH, Davila M, Gil KM, Askanazi J, and Kinney JM. Effect of carbohydrate intake on de novo lipogenesis in human adipose tissue. Am J Physiol 253: E664-669, 1987.
6. Chen L, Na R, Gu M, Salmon AB, Liu Y, Liang H, Qi W, Van Remmen H, Richardson A, and Ran Q. Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice. Aging Cell 7: 866-878, 2008. (Pubitemid 352749440)
7. Choi KL, Wang Y, Tse CA, Lam KS, Cooper GJ, and Xu A. Proteomic analysis of adipocyte differentiation: Evidence that alpha2 macroglobulin is involved in the adipose conversion of 3T3 L1 preadipocytes. Proteomics 4: 1840-1848, 2004. (Pubitemid 38738338)
8. Cox AG, Winterbourn CC, and Hampton MB. Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling. Biochem J 425: 313-325, 2009.
9. De Pauw A, Tejerina S, Raes M, Keijer J, and Arnould T. Mitochondrial (dys)function in adipocyte (de)differentiation and systemic metabolic alterations. Am J Pathol 175: 927-939, 2009.
10. Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, and Shimomura I. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 114: 1752-1761, 2004. (Pubitemid 40385531)
11. Green H and Kehinde O. An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 5: 19-27, 1975.
12. Ha H and Endou H. Lipid peroxidation in isolated rat nephron segments. Am J Physiol 263: F201-207, 1992.
13. Hattori F, Murayama N, Noshita T, and Oikawa S. Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo. J Neurochem 86: 860-868, 2003. (Pubitemid 36988798)
14. Hiroi M, Nagahara Y, Miyauchi R, Misaki Y, Goda T, Kasezawa N, Sasaki S, and Yamakawa-Kobayashi K. The combination of genetic variations in the PRDX3 gene and dietary fat intake contribute to obesity risk. Obesity (Silver Spring) 19: 882-887, 2011.
15. Imhoff BR and Hansen JM. Extracellular redox environments regulate adipocyte differentiation. Differentiation 80: 31-39, 2010.
16. Iyer A, Fairlie DP, Prins JB, Hammock BD, and Brown L. Inflammatory lipid mediators in adipocyte function and obesity. Nat Rev Endocrinol 6: 71-82, 2010.
17. Johnson PR and Hirsch J. Cellularity of adipose depots in six strains of genetically obese mice. J Lipid Res 13: 2-11, 1972.
18. Kahn BB and Flier JS. Obesity and insulin resistance. J Clin Invest 106: 473-481, 2000. (Pubitemid 30666380)
19. Kanda Y, Hinata T, Kang SW, and Watanabe Y. Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells. Life Sci 89: 250-258, 2011.
20. Keaney JF,Jr, Larson MG, Vasan RS, Wilson PW, Lipinska I, Corey D, Massaro JM, Sutherland P, Vita JA, Benjamin EJ, and Framingham Study. Obesity and systemic oxidative stress: Clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol 23: 434-439, 2003. (Pubitemid 36337219)
21. Kim KB, Kim BW, Choo HJ, Kwon YC, Ahn BY, Choi JS, Lee JS, and Ko YG. Proteome analysis of adipocyte lipid rafts reveals that gC1qR plays essential roles in adipogenesis and insulin signal transduction. Proteomics 9: 2373-2382, 2009.
22. Kim MH, Kim I, Kim SH, Jung MK, Han S, Lee JE, Nam JS, Lee SK, and Bang SI. Cryopreserved human adipogenicdifferentiated pre-adipocytes: A potential new source for adipose tissue regeneration. Cytotherapy 9: 468-476, 2007. (Pubitemid 47386684)
23. Koh EH, Park JY, Park HS, Jeon MJ, Ryu JW, Kim M, Kim SY, Kim MS, Kim SW, Park IS, Youn JH, and Lee KU. Essential role of mitochondrial function in adiponectin synthesis in adipocytes. Diabetes 56: 2973-2981, 2007. (Pubitemid 350223632)
24. Kratchmarova I, Kalume DE, Blagoev B, Scherer PE, Podtelejnikov AV, Molina H, Bickel PE, Andersen JS, Fernandez MM, Bunkenborg J, Roepstorff P, Kristiansen K, Lodish HF, Mann M, and Pandey A. A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes. Mol Cell Proteomics 1: 213-222, 2002.
25. Lee H, Lee YJ, Choi H, Ko EH, and Kim JW. Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion. J Biol Chem 284: 10601-10609, 2009.
26. Lee YS, Kim AY, Choi JW, Kim M, Yasue S, Son HJ, Masuzaki H, Park KS, and Kim JB. Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress. Mol Endocrinol 22: 2176-2189, 2008.
27. Levine RL, Wehr N, Williams JA, Stadtman ER, and Shacter E. Determination of carbonyl groups in oxidized proteins. Methods Mol Biol 99: 15-24, 2000.
28. Li L, Kaifu T, Obinata M, and Takai T. Peroxiredoxin IIIdeficiency sensitizes macrophages to oxidative stress. J Biochem 145: 425-427, 2009.
29. Li L, Shoji W, Oshima H, Obinata M, Fukumoto M, and Kanno N. Crucial role of peroxiredoxin III in placental antioxidant defense of mice. FEBS Lett 582: 2431-2434, 2008.
30. Li L, Shoji W, Takano H, Nishimura N, Aoki Y, Takahashi R, Goto S, Kaifu T, Takai T, and Obinata M. Increased susceptibility of MER5 (peroxiredoxin III) knockout mice to LPS-induced oxidative stress. Biochem Biophys Res Commun 355: 715-721, 2007. (Pubitemid 46330210)
31. Matsushima S, Ide T, Yamato M, Matsusaka H, Hattori F, Ikeuchi M, Kubota T, Sunagawa K, Hasegawa Y, Kurihara T, Oikawa S, Kinugawa S, and Tsutsui H. Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation 113: 1779-1786, 2006. (Pubitemid 43958471)
32. Nadler ST, Stoehr JP, Schueler KL, Tanimoto G, Yandell BS, and Attie AD. The expression of adipogenic genes is decreased in obesity and diabetes mellitus. Proc Natl Acad Sci USA 97: 11371-11376, 2000.
33. Nicolson GL. Metabolic syndrome and mitochondrial function: Molecular replacement and antioxidant supplements to prevent membrane peroxidation and restore mitochondrial function. J Cell Biochem 100: 1352-1369, 2007. (Pubitemid 46515570)
34. Pfluger PT, Herranz D, Velasco-Miguel S, Serrano M, and Tschop MH. Sirt1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci USA 105: 9793-9798, 2008. (Pubitemid 352031379)
35. Rodbell M. Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis. J Biol Chem 239: 375-380, 1964.
36. Samuni Y, Cook JA, Choudhuri R, Degraff W, Sowers AL, Krishna MC, and Mitchell JB. Inhibition of adipogenesis by Tempol in 3T3-L1 cells. Free Radic Biol Med 49: 667-673, 2010.
37. Smyth S and Heron A. Diabetes and obesity: The twin epidemics Nat Med 12: 75-80, 2006. (Pubitemid 43050080)
38. Trujillo ME and Scherer PE. Adipose tissue-derived factors: Impact on health and disease. Endocr Rev 27: 762-778, 2006. (Pubitemid 44936059)
39. Van Gaal LF, Mertens IL, and De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 444: 875-880, 2006. (Pubitemid 46028447)
40. Welsh GI, Griffiths MR, Webster KJ, Page MJ, and Tavare JM. Proteome analysis of adipogenesis. Proteomics 4: 1042-1051, 2004. (Pubitemid 38445962)
41. Wilson-Fritch L, Burkart A, Bell G, Mendelson K, Leszyk J, Nicoloro S, Czech M, and Corvera S. Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone. Mol Cell Biol 23: 1085-1094, 2003. (Pubitemid 36133524)
42. Zvonic S, Lefevre M, Kilroy G, Floyd ZE, DeLany JP, Kheterpal I, Gravois A, Dow R, White A, Wu X, and Gimble JM. Secretome of primary cultures of human adiposederived stem cells: Modulation of serpins by adipogenesis. Mol Cell Proteomics 6: 18-28, 2007. (Pubitemid 46152688)