Phospholipase A 2 of peroxiredoxin 6 has a critical role in tumor necrosis factor-induced apoptosis

Cell Death and Differentiation

Volumn 18, Issue 10, 2011, Pages 1573-1583

  Kim, S Y ^a   Chun, E ^a,b   Lee, K Y ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

arachidonic acid; interleukin b; peroxiredoxin 6; phospholipase A 2; TNF induced apoptosis

Indexed keywords

ARACHIDONIC ACID; CYCLOHEXIMIDE; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PEROXIREDOXIN 6; PHOSPHOLIPASE A2; SHORT HAIRPIN RNA; TUMOR NECROSIS FACTOR ALPHA;

ANTIBIOTIC RESISTANCE; APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CYTOKINE PRODUCTION; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; ARACHIDONIC ACID; CASPASE 3; CASPASE 8; CELL CYCLE; CELL LINE; DNA FRAGMENTATION; HUMANS; IMMUNOBLOTTING; INTERLEUKIN-1BETA; INTERLEUKIN-6; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEROXIREDOXIN VI; PHOSPHOLIPASES A2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80052782891     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.21     Document Type: Article

References (40)

1. Rhee SG, Kang SW, Chang TS, Jeong W, Kim K. Peroxiredoxin, a novel family of peroxidases. IUBMB Life 2001; 52: 35-41. (Pubitemid 33769667)
2. Woo HA, Chae HZ, Hwang SC, Yang KS, Kang SW, Kim K et al. Reversing the inactivation of peroxiredoxins caused by cysteine sulfinic acid formation. Science 2003; 300: 653-656. (Pubitemid 36520592)
3. Rhee SG, Chae HZ, Kim K. Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic Biol Med 2005; 38: 1543-1552. (Pubitemid 40726061)
4. Wood ZA, Poole LB, Karplus PA. Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science 2003; 300: 650-653. (Pubitemid 36520591)
5. Chen JW, Dodia C, Feinstein SI, Jain MK, Fisher AB. 1-Cys peroxiredoxin, a bifunctional enzyme with glutathione peroxidase and phospholipase A2 Activities. J Biol Chem 2000; 275: 28421-28427.
6. 2-dependent hyperoxidation of peroxiredoxin 6 (Prdx6) plays a role in cellular toxicity via up-regulation of iPLA2 activity. J Biol Chem 2008; 283: 33563-33568.
7. 2-induced oxidative stress. J Cell Biochem 2008; 104: 1274-1285. (Pubitemid 351961700)
8. Wang Y, Phelan SA, Manevich Y, Feinstein SI, Fisher AB. Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia. Am J Respir Cell Mol Biol 2006; 34: 481-486.
9. Akiba S, Sato T. Cellular function of calcium-independent phospholipase A2. Biol Pharm Bull 2004; 27: 1174-1178.
10. Wolf MJ, Wang J, Turk J, Gross RW. Depletion of intracellular calcium stores activates smooth muscle cell calcium-independent phospholipase A2. A novel mechanism underlying arachidonic acid mobilization. J Biol Chem 1997; 272: 1522-1526. (Pubitemid 27043230)
11. Chang XZ, Li DQ, Hou YF, Wu J, Lu JS, Di GH et al. Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer. Breast Cancer Res 2007; 9: R76.
12. Sun GY, Shelat PB, Jensen MB, He Y, Sun AY, Simonyi A. Phospholipases A2 and inflammatory responses in the central nervous system. Neuromolecular Med 2010; 12: 133-148.
13. Kim SJ, Gershov D, Ma X, Brot N, Elkon KB. I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation. J Exp Med 2002; 196: 655-665. (Pubitemid 35024443)
14. Atsumi G, Tajima M, Hadano A, Nakatani Y, Murakami M, Kudo I. Fas-induced arachidonic acid release is mediated by Ca2+-independent phospholipase A2 but not cytosolic phospholipase A2, which undergoes proteolytic inactivation. J Biol Chem 1998; 273: 13870-13877. (Pubitemid 28268439)
15. Song Y, Wilkins P, Hu W, Murthy KS, Chen J, Lee Z et al. Inhibition of calcium-independent phospholipase A(2) suppresses proliferation and tumorigenicity of ovarian carcinoma cells. Biochem J 2007; 406: 427-436. (Pubitemid 47425449)
16. Fisher AB. Peroxiredoxin 6: A bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities. Antioxid Redox Signal 2010 [Epub ahead of print 4 October 2010].
17. Choi H, Chang JW, Jung YK. Peroxiredoxin 6 interferes with TRAIL-induced deathinducing signaling complex formation by binding to death effector domain caspase. Cell Death Differ 2010; 18: 405-414.
18. Manevich Y, Fisher AB. Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism. Free Radic Biol Med 2005; 38: 1422-1432. (Pubitemid 40693827)
19. Kim TS, Dodia C, Chen X, Hennigan BB, Jain M, Feinstein SI et al. Cloning and expression of rat lung acidic Ca(2+)-independent PLA2 and its organ distribution. Am J Physiol 1998; 274: L750-L761.
20. Cao Y, Pearman AT, Zimmerman GA, McIntyre TM, Prescott SM. Intracellular unesterified arachidonic acid signals apoptosis. Proc Natl Acad Sci USA 2000; 97: 11280-11285.
21. Chan TA, Morin PJ, Vogelstein B, Kinzler KW. Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. Proc Natl Acad Sci USA 1998; 95: 681-686. (Pubitemid 28083803)
22. Wissing D, Mouritzen H, Egeblad M, Poirier GG, Jaattela M. Involvement of caspasedependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis. Proc Natl Acad Sci USA 1997; 94: 5073-5077. (Pubitemid 27214738)
23. Duan L, Gan H, Arm J, Remold HG. Cytosolic phospholipase A2 participates with TNF-α in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra. J Immunol 2001; 166: 7469-7476. (Pubitemid 32525625)
24. Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G. The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 2009; 10: 241-247.
25. Miura M, Friedlander RM, Yuan J. Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway. Proc Natl Acad Sci USA 1995; 92: 8318-8322.
26. Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003; 114: 181-190. (Pubitemid 36936912)
27. Schütze S, Tchikov V, Schneider-Brachert W. Regulation of TNFR1 and CD95 signalling by receptor compartmentalization. Nat Rev Mol Cell Biol 2008; 8: 655-662. (Pubitemid 352032925)
28. Hsu H, Shu HB, Pan MG, Goeddel DV. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 1996; 84: 299-308. (Pubitemid 26042835)
29. Wissing D, Mouritzen H, Egeblad M, Poirier GG, Jää ttelä M. Involvement of caspasedependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis. Proc Natl Acad Sci USA 1997; 94: 5073-5077. (Pubitemid 27214738)
30. Clark MA, Chen MJ, Crooke ST, Bomalaski JS. Tumour necrosis factor (cachectin) induces phospholipase A2 activity and synthesis of a phospholipase A2-activating protein in endothelial cells. Biochem J 1988; 250: 125-132. (Pubitemid 18060776)
31. 2 activation and autoinduction of tumor necrosis factor gene expression by tumor necrosis factor. Cancer Res 1990; 50: 7101-7107.
32. Henderson LM, Moule SK, Chappell JB. The immediate activator of the NADPH oxidase is arachidonate not phosphorylation. Eur J Biochem 1993; 211: 157-162. (Pubitemid 23039509)
33. Cui XL, Douglas JG. Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells. Proc Natl Acad Sci USA 1997; 94: 3771-3776. (Pubitemid 27180448)
34. Cao Y, Pearman AT, Zimmerman GA, McIntyre TM, Prescott SM. Intracellular unesterified arachidonic acid signals apoptosis. Proc Natl Acad Sci USA 2000; 97: 11280-11285.
35. Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 2004; 430: 213-218. (Pubitemid 38902430)
36. Burns K, Martinon F, Tschopp J. New insights into the mechanism of IL-1β maturation. Curr Opin Immunol 2003; 15: 26-30. (Pubitemid 35454188)
37. 2 beta is dispensable in inflammasome activation and its inhibition by bromoenol lactone. J Innate Immun 2009; 6: 607-617.
38. Ikezono T, Wu T, Yao XL, Levine S, Logun C, Angus CW et al. Leukemia inhibitory factor induces the 85-kDa cytosolic phospholipase A2 gene expression in cultured human bronchial epithelial cells. Biochim Biophys Acta 1997; 1355: 121-130. (Pubitemid 27064038)
39. Wu T, Levine SJ, LawrenceMG, Logun C, Angus CW, Shelhamer JH. Interferon-gamma induces the synthesis and activation of cytosolic phospholipase A2. J Clin Invest 1994; 93: 571-577.
40. Wu T, Ikezono T, Angus CW, Shelhamer JH. Tumor necrosis factor-alpha induces the 85-kDa cytosolic phospholipase A2 gene expression in human bronchial epithelial cells. Biochim Biophys Acta 1996; 1310: 175-184.