Genomic editing tools to model human diseases with isogenic pluripotent stem cells

Stem Cells and Development

Volumn 23, Issue 22, 2014, Pages 2673-2686

  Kim, Huen Suk ^a   Bernitz, Jeffrey M ^a   Lee, Dung Fang ^a   Lemischka, Ihor R ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; ZINC FINGER NUCLEASE;

ADAPTIVE IMMUNITY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS SYSTEM; DISEASE MODEL; DNA BINDING; DNA CLEAVAGE; DNA END JOINING REPAIR; DNA METHYLATION; FEASIBILITY STUDY; GENE LOCUS; GENE MUTATION; GENETIC VARIABILITY; HUMAN; IN VITRO STUDY; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PHENOTYPE; PLURIPOTENT STEM CELL; PROMOTER REGION; REVIEW; ZINC FINGER MOTIF; GENETIC ENGINEERING; GENETICS; HEREDITY; HUMAN GENOME; METABOLISM; PROCEDURES;

GENETIC ENGINEERING; GENETIC PROCESSES; GENOME, HUMAN; HUMANS; INDUCED PLURIPOTENT STEM CELLS;

EID: 84913600795     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2014.0167     Document Type: Review

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