Identification of an insulator in AAVS1, a preferred region for integration of adeno-associated virus DNA

Journal of Virology

Volumn 77, Issue 16, 2003, Pages 9000-9007

  Ogata, Toshihiko ^a   Kozuka, Takuyo ^b   Kanda, Tadahito ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b CANCER INSTITUTE HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENO ASSOCIATED VIRUS; APOPTOSIS; ARTICLE; CHROMOSOME SEGREGATION; CONFORMATIONAL TRANSITION; ENHANCER REGION; GENE EXPRESSION REGULATION; GENE LOCATION; GENETIC RECOMBINATION; GENOTOXICITY; HETEROCHROMATIN; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REPORTER GENE; VIRUS DNA CELL DNA INTERACTION; VIRUS GENOME; VIRUS IDENTIFICATION;

ANIMALS; BASE SEQUENCE; CELL LINE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 19; DEOXYRIBONUCLEASE I; DEPENDOVIRUS; DNA PRIMERS; DNA, VIRAL; ENHANCER ELEMENTS (GENETICS); GENETIC VECTORS; HUMANS; INSULATOR ELEMENTS; TRANSGENES; VIRUS INTEGRATION;

EID: 0042208122     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.16.9000-9007.2003     Document Type: Article

References (35)

1. Bell, A. C., A. G. West, and G. Felsenfeld. 1999. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 98:387-396.
2. Berns, K. I., and R. A. Bohenzky. 1987. Adeno-associated viruses: an update. Adv. Virus Res. 32:243-306.
3. Berns, K. I., and C. Giraud. 1996. Biology of adeno-associated virus. Curr. Top. Microbiol. Immunol. 218:1-23.
4. Buller, R. M., J. E. Janik, E. D. Sebring, and J. A. Rose. 1981. Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication. J. Virol. 40:241-247.
5. Burgess-Beusse, B., C. Farrell, M. Gaszner, M. Litt, V. Mutskov, F. Recillas-Targa, M. Simpson, A. West, and G. Felsenfeld. 2002. The insulation of genes from external enhancers and silencing chromatin. Proc. Natl. Acad. Sci. USA 99:16433-16437.
6. Carter, B. J., C. A. Laughlin, L. M. de la Maza, and M. Myers. 1979. Adeno-associated virus autointerference. Virology 92:449-462.
7. Chen, S., and V. G. Corces. 2001. The Gypsy insulator of Drosophila affects chromatin structure in a directional manner. Genetics 159:1649-1658.
8. Cheung, A. K., M. D. Hoggan, W. W. Hauswirth, and K. I. Berns. 1980. Integration of the adeno-associated virus genome into cellular DNA in latently infected human Detroit 6 cells. J. Virol. 33:739-748.
9. Chung, J. H., A. C. Bell, and G. Felsenfeld. 1997. Characterization of the chicken b-globin insulator. Proc. Natl. Acad. Sci. USA 94:575-580.
10. Georg-Fries, B., S. Biederlack, J. Wolf, and H. zur Hausen. 1984. Analysis of proteins, helper dependence, and seroepidemiology of a new human parvovirus. Virology 134:64-71.
11. Giraud, C., E. Winocour, and K. I. Berns. 1994. Site-specific integration by adeno-associated virus is directed by a cellular DNA sequence. Proc. Natl. Acad. Sci. USA 91:10039-10043.
12. Giraud, C., E. Winocour, and K. I. Berns. 1995. Recombinant junctions formed by site-specific integration of adeno-associated virus into an episome. J. Virol. 69:6917-6924.
13. Gross, D. S., and W. T. Garrard. 1988. Nuclease hypersensitive sites in chromatin. Annu. Rev. Biochem. 57:159-197.
14. Handa, H., K. Shiroki, and H. Shimojo. 1977. Establishment and characterization of KB cell lines latently infected with adeno-associated virus type 1. Virology 82:84-92.
15. Huser, D., S. Weger, and R. Heilbronn. 2002. Kinetics and frequency of adeno-associated virus site-specific integration into human chromosome 19 monitored by quantitive real-time PCR. J. Virol. 76:7554-7559.
16. Kalos, M., and R. E. K. Fournier. 1995. Position-independent transgene expression mediated by boundary elements from the apolipoprotein B chromatin domain. Mol. Cell. Biol. 15:198-207.
17. Kotin, R. M., R. M. Linden, and K. I. Berns. 1992. Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination. EMBO J. 11:5071-5076.
18. Kotin, R. M., J. C. Menninger, D. C. Ward, and K. I. Berns. 1991. Mapping and direct visualization of a region-specific viral DNA integration site on chromosome 19q13-qter. Genomics 10:831-834.
19. Kotin, R. M., M. Siniscalco, R. J. Samulski, X. Zhu, L. Hunter, C. A. Laughlin, S. McLaughlin, N. Muzyczka, M. Rocchi, and K. I. Berns. 1990. Site-specific integration by adeno-associated virus. Proc. Natl. Acad. Sci. USA 87:2211-2215.
20. Lamartina, S., E. Sporeno, E. Fattori, and C. Toniatti. 2000. Characteristics of the adeno-associated virus preintegration site in human chromosome 19: open chromatin conformation and transcription -competent environment. J. Virol. 74:7671-7677.
21. Li, Q., and G. Stamatoyannopoulos. 1994. Hypersensitive site 5 of the human b focus control region functions as a chromatin insulator. Blood 84: 1399-1401.
22. McPherson, R. A., L. J. Rosenthal, and J. A. Rose. 1985. Human cytomegalovirus completely helps adeno-associated virus replication. Virology 147: 217-222.
23. Mishra, L., and J. A. Rose. 1990. Adeno-associated virus DNA replication is induced by genes that are essential for HSV-1 DNA synthesis. Virology 179:632-639.
24. Mori, S., M. Murakami, T. Takeuchi, T. Kozuka, and T. Kanda. 2002. Rescue of AAV by antibody-induced Fas-mediated apoptosis from viral DNA integrated in HeLa chromosome. Virology 301:90-98.
25. Mutskov, V. J., C. M. Ferrell, P. A. Wade, A. P. Wolffe, and G. Felsenfeld. 2002. The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation. Genes Dev. 16:1540-1554.
26. Pikaart, M. J., F. Recillas-Targa, and G. Felsenfeld. 1998. Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators. Genes Dev. 12:2852-2862.
27. Richardson, W. D., and H. Westphal. 1981. A cascade of adenovirus early functions is required for expression of adeno-associated virus. Cell 27:133-141.
28. Roeder, G. S. 1997. Meiotic chromosomes: it takes two to tango. Genes Dev. 11:2600-2621.
29. Saitoh, N., A. C. Bell, F. Recilla-Targa, A. G. West, M. Simpson, M. Pikaart, and G. Felsenfeld. 2000. Structural and functional conservation at the boundaries of the chicken β-globin domain. EMBO J. 19:2315-2322.
30. Surosky, R. T., M. Urabe, S. G. Godwin, S. A. McQuiston, G. J. Kurtzman, K. Ozawa, and G. Natsoulis. 1997. Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome. J. Virol. 71:7951-7959.
31. Weindler, F. W., and R. Heilbronn. 1991. A subset of herpes simplex virus replication genes provides helper functions for productive adeno-associated virus replication. J. Virol. 65:2476-2483.
32. West, M. H., J. P. Trempe, J. D. Tratschin, and B. J. Carter. 1987. Gene expression in adeno-associated virus vectors: the effects of chimeric mRNA structure, helper virus, and adenovirus VA1 RNA. Virology 160:38-47.
33. Yakinoglu, A. O., R. Heilbronn, A. Burkle, J. R. Schlehofer, and H. zur Hausen. 1988. DNA amplification of adeno-associated virus as a response to cellular genotoxic stress. Cancer Res. 48:3123-3129.
34. Yates, J. L., and N. Guan. 1991. Epstein-Barr virus-derived plasmids replicate only once per cell cycle and are not amplified after entry into cells. J. Virol. 65:483-488.
35. Zaret, K. 1999. In vivo analysis of chromatin structure. 1999. Methods Enzymol. 304:612-626.