Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription

Cell

Volumn 155, Issue 6, 2013, Pages 1351-

  Ambasudhan, Rajesh ^a   Ryan, Scott D ^a   Dolatabadi, Nima ^a   Chan, Shing Fai ^a   Zhang, Xiaofei ^a   Akhtar, Mohd Waseem ^a   Parker, James ^a   Soldner, Frank ^b   Sunico, Carmen R ^a   Nagar, Saumya ^a   Talantova, Maria ^a   Lee, Brian ^a   Lopez, Kevin ^a   Nutter, Anthony ^a   Shan, Bing ^c   Molokanova, Elena ^a   Zhang, Yaoyang ^c   Han, Xuemei ^c   Nakamura, Tomohiro ^a   Masliah, Eliezer ^e   Yates III, John R ^c   Nakanishi, Nobuki ^a   Andreyev, Aleksander Y ^d   Okamoto, Shu Ichi ^a   Jaenisch, Rudolf ^a,b   Lipton, Stuart A ^a,e   more..

^a BURNHAM INSTITUTE   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; MYOCYTE ENHANCER FACTOR 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; MEF2C PROTEIN, HUMAN; PARAQUAT; PPARGC1A PROTEIN, HUMAN; REACTIVE NITROGEN SPECIES; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; DOPAMINERGIC NERVE CELL; GENE EXPRESSION; GENOTYPE ENVIRONMENT INTERACTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; NITROSATIVE STRESS; NITROSYLATION; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MITOCHONDRION; MUTATION; NERVE CELL; PATHOLOGY; SUBSTANTIA NIGRA; DRUG EFFECTS; TOXICITY;

ALPHA-SYNUCLEIN; GENE-ENVIRONMENT INTERACTION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MEF2 TRANSCRIPTION FACTORS; MITOCHONDRIA; MUTATION; NEURONS; OXIDATIVE STRESS; PARAQUAT; PARKINSON DISEASE; REACTIVE NITROGEN SPECIES; SUBSTANTIA NIGRA; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84890115517     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.11.009     Document Type: Article

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