A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells

Stem Cells

Volumn 27, Issue 8, 2009, Pages 1836-1846

  Xue, Haipeng ^a,b   Wu, Sen ^c   Papadeas, Sophia T ^d   Spusta, Steve ^e   Swistowska, Anna Maria ^e   MacArthur, Chad C ^a   Mattson, Mark P ^b   Maragakis, Nicholas J ^d   Capecchi, Mario R ^c   Rao, Mahendra S ^a,b   Zeng, Xianmin ^e   Liu, Ying ^a,b  

^a Life Technologies   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Basic helix loop helix transcription factor; Embryonic stem cell; Gene targeting; Gliogenesis; Neurogenesis; Olig2

Indexed keywords

GREEN FLUORESCENT PROTEIN; HELIX LOOP HELIX PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; RECOMBINANT PROTEIN; RETINOIC ACID; SONIC HEDGEHOG PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL LINE; CELL LINEAGE; CELL STRAIN BG01; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION PROFILING; GENE TARGETING; GLIA CELL; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MALE; MOTONEURON; NONHUMAN; OLIGODENDROGLIA; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; RAT;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; GENE KNOCK-IN TECHNIQUES; GENE TARGETING; HEDGEHOG PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; NERVE TISSUE PROTEINS; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINATION, GENETIC; TRANSFECTION;

ERINACEIDAE; RATTUS; RODENTIA;

EID: 69249138761     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.129     Document Type: Article

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