-
1
-
-
33845397703
-
Mechanisms of disease: Ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors
-
Abate N, Chandalia M, Di Paola R, et al. (2006). Mechanisms of disease: ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors. Nat Clin Pract Endocrinol Metab 2:694-701.
-
(2006)
Nat Clin Pract Endocrinol Metab
, vol.2
, pp. 694-701
-
-
Abate, N.1
Chandalia, M.2
Di Paola, R.3
-
2
-
-
33745742679
-
International Union of Pharmacology LVIII: Update on the P2Y G protein-coupled nucleotide receptors: From molecular mechanisms and pathophysiology to therapy
-
Abbracchio MP, Burnstock G, Boeynaems JM, et al. (2006). International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev 58:281-341.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 281-341
-
-
Abbracchio, M.P.1
Burnstock, G.2
Boeynaems, J.M.3
-
4
-
-
0031047221
-
Differential regulation and function of CD73, a glycosyl-phosphatidylinositol-linked 70-kD adhesion molecule, on lymphocytes and endothelial cells
-
Airas L, Niemela J, Salmi M, et al. (1997). Differential regulation and function of CD73, a glycosyl-phosphatidylinositol-linked 70-kD adhesion molecule, on lymphocytes and endothelial cells. J Cell Biol 136:421-31.
-
(1997)
J Cell Biol
, vol.136
, pp. 421-431
-
-
Airas, L.1
Niemela, J.2
Salmi, M.3
-
5
-
-
59449098985
-
Gene therapy for immunodeficiency due to adenosine deaminase deficiency
-
Aiuti A, Cattaneo F, Galimberti S, et al. (2009). Gene therapy for immunodeficiency due to adenosine deaminase deficiency. N Engl J Med 360:447-58.
-
(2009)
N Engl J Med
, vol.360
, pp. 447-458
-
-
Aiuti, A.1
Cattaneo, F.2
Galimberti, S.3
-
6
-
-
84901850023
-
Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/ phosphodiesterase, ecto-50-nucleotidase, and alkaline phosphatase inhibitors
-
Al-Rashida M, Iqbal J. (2014). Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/ phosphodiesterase, ecto-50-nucleotidase, and alkaline phosphatase inhibitors. Med Res Rev 34:703-43.
-
(2014)
Med Res Rev
, vol.34
, pp. 703-743
-
-
Al-Rashida, M.1
Iqbal, J.2
-
7
-
-
84869754551
-
NPP4 is a procoagulant enzyme on the surface of vascular endothelium
-
Albright RA, Chang WC, Robert D, et al. (2012). NPP4 is a procoagulant enzyme on the surface of vascular endothelium. Blood 120:4432-40.
-
(2012)
Blood
, vol.120
, pp. 4432-4440
-
-
Albright, R.A.1
Chang, W.C.2
Robert, D.3
-
8
-
-
84893668900
-
The molecular basis of purinergic signal metabolism by ecto-nucleotide pyrophosphatase/ phosphodiesterases 4 and 1 and implications in stroke
-
Albright RA, Ornstein DL, Cao W, et al. (2014). The molecular basis of purinergic signal metabolism by ecto-nucleotide pyrophosphatase/ phosphodiesterases 4 and 1 and implications in stroke. J Biol Chem 289:3294-306.
-
(2014)
J Biol Chem
, vol.289
, pp. 3294-3306
-
-
Albright, R.A.1
Ornstein, D.L.2
Cao, W.3
-
9
-
-
79955944679
-
Different role of CD73 in leukocyte trafficking via blood and lymph vessels
-
Algars A, Karikoski M, Yegutkin GG, et al. (2011). Different role of CD73 in leukocyte trafficking via blood and lymph vessels. Blood 117:4387-93.
-
(2011)
Blood
, vol.117
, pp. 4387-4393
-
-
Algars, A.1
Karikoski, M.2
Yegutkin, G.G.3
-
10
-
-
84877630607
-
Ectonucleotidases distribution in human cyclic and postmenopausic endometrium
-
Aliagas E, Vidal A, Torrejon-Escribano B, et al. (2013). Ectonucleotidases distribution in human cyclic and postmenopausic endometrium. Purinergic Signal 9:227-37.
-
(2013)
Purinergic Signal
, vol.9
, pp. 227-237
-
-
Aliagas, E.1
Vidal, A.2
Torrejon-Escribano, B.3
-
11
-
-
21144434783
-
Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice
-
Anderson HC, Harmey D, Camacho NP, et al. (2005). Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice. Am J Pathol 166:1711-20.
-
(2005)
Am J Pathol
, vol.166
, pp. 1711-1720
-
-
Anderson, H.C.1
Harmey, D.2
Camacho, N.P.3
-
12
-
-
84860800094
-
Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders
-
Antonioli L, Colucci R, La Motta C, et al. (2012). Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders. Curr Drug Targets 13: 842-62.
-
(2012)
Curr Drug Targets
, vol.13
, pp. 842-862
-
-
Antonioli, L.1
Colucci, R.2
La Motta, C.3
-
13
-
-
84878614399
-
CD39 and CD73 in immunity and inflammation
-
Antonioli L, Pacher P, Vizi ES, et al. (2013). CD39 and CD73 in immunity and inflammation. Trends Mol Med 19:355-67.
-
(2013)
Trends Mol Med
, vol.19
, pp. 355-367
-
-
Antonioli, L.1
Pacher, P.2
Vizi, E.S.3
-
14
-
-
0344011492
-
Possible role of cell surface H+-ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells
-
Arakaki N, Nagao T, Niki R, et al. (2003). Possible role of cell surface H+-ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells. Mol Cancer Res 1:931-9.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 931-939
-
-
Arakaki, N.1
Nagao, T.2
Niki, R.3
-
15
-
-
84901764077
-
Prostatic acid phosphatase is the main acid phosphatase with 50-ectonucleotidase activity in the male mouse saliva and regulates salivation
-
Araujo CL, Quintero IB, Kipar A, et al. (2014). Prostatic acid phosphatase is the main acid phosphatase with 50-ectonucleotidase activity in the male mouse saliva and regulates salivation. Am J Physiol Cell Physiol 306:C1017-27.
-
(2014)
Am J Physiol Cell Physiol
, vol.306
, pp. C1017-C1027
-
-
Araujo, C.L.1
Quintero, I.B.2
Kipar, A.3
-
17
-
-
84874284563
-
Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis
-
Bai Z, Cai L, Umemoto E, et al. (2013). Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis. J Immunol 190: 2036-48.
-
(2013)
J Immunol
, vol.190
, pp. 2036-2048
-
-
Bai, Z.1
Cai, L.2
Umemoto, E.3
-
18
-
-
47649107368
-
CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation
-
Banz Y, Beldi G, Wu Y, et al. (2008). CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation. Br J Haematol 142:627-37.
-
(2008)
Br J Haematol
, vol.142
, pp. 627-637
-
-
Banz, Y.1
Beldi, G.2
Wu, Y.3
-
19
-
-
33744928130
-
Nucleoside triphosphate diphosphohydrolase-2 is the ecto-ATPase of type i cells in taste buds
-
Bartel DL, Sullivan SL, Lavoie EG, et al. (2006). Nucleoside triphosphate diphosphohydrolase-2 is the ecto-ATPase of type I cells in taste buds. J Comp Neurol 497:1-12.
-
(2006)
J Comp Neurol
, vol.497
, pp. 1-12
-
-
Bartel, D.L.1
Sullivan, S.L.2
Lavoie, E.G.3
-
20
-
-
84876125245
-
ENTPD1/ CD39 is a promising therapeutic target in oncology
-
Bastid J, Cottalorda-Regairaz A, Alberici G, et al. (2012). ENTPD1/ CD39 is a promising therapeutic target in oncology. Oncogene 32: 1743-51.
-
(2012)
Oncogene
, vol.32
, pp. 1743-1751
-
-
Bastid, J.1
Cottalorda-Regairaz, A.2
Alberici, G.3
-
21
-
-
55649124110
-
The role of ecto-50- nucleotidase/CD73 in glioma cell line proliferation
-
Bavaresco L, Bernardi A, Braganhol E, et al. (2008). The role of ecto-50- nucleotidase/CD73 in glioma cell line proliferation. Mol Cell Biochem 319:61-8.
-
(2008)
Mol Cell Biochem
, vol.319
, pp. 61-68
-
-
Bavaresco, L.1
Bernardi, A.2
Braganhol, E.3
-
22
-
-
0023917654
-
A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay
-
Baykov AA, Evtushenko OA, Avaeva SM. (1988). A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay. Anal Biochem 171:266-70.
-
(1988)
Anal Biochem
, vol.171
, pp. 266-270
-
-
Baykov, A.A.1
Evtushenko, O.A.2
Avaeva, S.M.3
-
23
-
-
0032928118
-
Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase
-
Beigi R, Kobatake E, Aizawa M, et al. (1999). Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase. Am J Physiol 276:C267-78.
-
(1999)
Am J Physiol
, vol.276
, pp. C267-C278
-
-
Beigi, R.1
Kobatake, E.2
Aizawa, M.3
-
24
-
-
31144457368
-
Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: Implications for modulation of multiple homeostatic systems including feeding and sleep-wake behaviors
-
Belcher SM, Zsarnovszky A, Crawford PA, et al. (2006). Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: implications for modulation of multiple homeostatic systems including feeding and sleep-wake behaviors. Neuroscience 137:1331-46.
-
(2006)
Neuroscience
, vol.137
, pp. 1331-1346
-
-
Belcher, S.M.1
Zsarnovszky, A.2
Crawford, P.A.3
-
25
-
-
84895077142
-
The effect of intravenous interferon-beta-1a (FP-1201) on lung CD73 expression and on acute respiratory distress syndrome mortality: An open-label study
-
Bellingan G, Maksimow M, Howell DC, et al. (2014). The effect of intravenous interferon-beta-1a (FP-1201) on lung CD73 expression and on acute respiratory distress syndrome mortality: an open-label study. Lancet Respir Med 2:98-107.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 98-107
-
-
Bellingan, G.1
Maksimow, M.2
Howell, D.C.3
-
26
-
-
0020074864
-
A one-step determination of serum 50-nucleotidase using a centrifugal analyzer
-
Bertrand A, Buret J. (1982). A one-step determination of serum 50-nucleotidase using a centrifugal analyzer. Clin Chim Acta 119: 275-84.
-
(1982)
Clin Chim Acta
, vol.119
, pp. 275-284
-
-
Bertrand, A.1
Buret, J.2
-
28
-
-
0032570814
-
Adenosine deaminasedeficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency
-
Blackburn MR, Datta SK, Kellems RE. (1998). Adenosine deaminasedeficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency. J Biol Chem 273: 5093-100.
-
(1998)
J Biol Chem
, vol.273
, pp. 5093-5100
-
-
Blackburn, M.R.1
Datta, S.K.2
Kellems, R.E.3
-
29
-
-
13444262230
-
Adenosine deaminase deficiency: Metabolic basis of immune deficiency and pulmonary inflammation
-
Blackburn MR, Kellems RE. (2005). Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation. Adv Immunol 86:1-41.
-
(2005)
Adv Immunol
, vol.86
, pp. 1-41
-
-
Blackburn, M.R.1
Kellems, R.E.2
-
30
-
-
0034679559
-
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
-
Blackburn MR, Volmer JB, Thrasher JL, et al. (2000). Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. J Exp Med 192:159-70.
-
(2000)
J Exp Med
, vol.192
, pp. 159-170
-
-
Blackburn, M.R.1
Volmer, J.B.2
Thrasher, J.L.3
-
31
-
-
84876373418
-
Adenosine kinase: Exploitation for therapeutic gain
-
Boison D. (2013). Adenosine kinase: exploitation for therapeutic gain. Pharmacol Rev 65:906-43.
-
(2013)
Pharmacol Rev
, vol.65
, pp. 906-943
-
-
Boison, D.1
-
32
-
-
83455210938
-
Learning about the functions of NME/ NM23: Lessons from knockout mice to silencing strategies
-
Boissan M, Lacombe ML. (2011). Learning about the functions of NME/ NM23: lessons from knockout mice to silencing strategies. Naunyn Schmiedebergs Arch Pharmacol 384:421-31.
-
(2011)
Naunyn Schmiedebergs Arch Pharmacol
, vol.384
, pp. 421-431
-
-
Boissan, M.1
Lacombe, M.L.2
-
33
-
-
84880845808
-
Ecto-50-nucleotidase on immune cells protects from adverse cardiac remodeling
-
Bonner F, Borg N, Jacoby C, et al. (2013). Ecto-50-nucleotidase on immune cells protects from adverse cardiac remodeling. Circ Res 113: 301-12.
-
(2013)
Circ Res
, vol.113
, pp. 301-312
-
-
Bonner, F.1
Borg, N.2
Jacoby, C.3
-
34
-
-
84871784120
-
Lack of ecto-50-nucleotidase (CD73) promotes arteriogenesis
-
Boring YC, Flogel U, Jacoby C, et al. (2013). Lack of ecto-50-nucleotidase (CD73) promotes arteriogenesis. Cardiovasc Res 97:88-96.
-
(2013)
Cardiovasc Res
, vol.97
, pp. 88-96
-
-
Boring, Y.C.1
Flogel, U.2
Jacoby, C.3
-
35
-
-
33749261659
-
Adenosine 50- triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
-
Bours MJL, Swennen ELR, Di Virgilio F, et al. (2006). Adenosine 50- triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 112:358-404.
-
(2006)
Pharmacol Ther
, vol.112
, pp. 358-404
-
-
Bours, M.J.L.1
Swennen, E.L.R.2
Di Virgilio, F.3
-
36
-
-
0034515728
-
Assignment of ecto-nucleoside triphosphate diphosphohydrolase-1/cd39 expression to microglia and vasculature of the brain
-
Braun N, Sevigny J, Robson SC, et al. (2000). Assignment of ecto-nucleoside triphosphate diphosphohydrolase-1/cd39 expression to microglia and vasculature of the brain. Eur J Neurosci 12: 4357-66.
-
(2000)
Eur J Neurosci
, vol.12
, pp. 4357-4366
-
-
Braun, N.1
Sevigny, J.2
Robson, S.C.3
-
37
-
-
1042291303
-
Association of the ecto- ATPase NTPDase2 with glial cells of the peripheral nervous system
-
Braun N, Sevigny J, Robson SC, et al. (2004). Association of the ecto- ATPase NTPDase2 with glial cells of the peripheral nervous system. Glia 45:124-32.
-
(2004)
Glia
, vol.45
, pp. 124-132
-
-
Braun, N.1
Sevigny, J.2
Robson, S.C.3
-
38
-
-
80054107337
-
Inactivation of CD73 promotes atherogenesis in apolipoprotein E-deficient mice
-
Buchheiser A, Ebner A, Burghoff S, et al. (2011). Inactivation of CD73 promotes atherogenesis in apolipoprotein E-deficient mice. Cardiovasc Res 92:338-47.
-
(2011)
Cardiovasc Res
, vol.92
, pp. 338-347
-
-
Buchheiser, A.1
Ebner, A.2
Burghoff, S.3
-
39
-
-
84891133400
-
Purinergic signaling and blood vessels in health and disease
-
Burnstock G, Ralevic V. (2014). Purinergic signaling and blood vessels in health and disease. Pharmacol Rev 66:102-92.
-
(2014)
Pharmacol Rev
, vol.66
, pp. 102-192
-
-
Burnstock, G.1
Ralevic, V.2
-
40
-
-
23844499087
-
Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface
-
Burrell HE, Wlodarski B, Foster BJ, et al. (2005). Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface. J Biol Chem 280:29667-76.
-
(2005)
J Biol Chem
, vol.280
, pp. 29667-29676
-
-
Burrell, H.E.1
Wlodarski, B.2
Foster, B.J.3
-
41
-
-
0034786062
-
Evidence supporting the Nucleotide Axis Hypothesis: ATP release and metabolism by coronary endothelium
-
Buxton IL, Kaiser RA, Oxhorn BC, et al. (2001). Evidence supporting the Nucleotide Axis Hypothesis: ATP release and metabolism by coronary endothelium. Am J Physiol Heart Circ Physiol 281: H1657-66.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.281
, pp. H1657-H1666
-
-
Buxton, I.L.1
Kaiser, R.A.2
Oxhorn, B.C.3
-
42
-
-
77950023386
-
Purinergic mechanisms in breast cancer support intravasation, extravasation and angiogenesis
-
Buxton IL, Yokdang N, Matz RM. (2010). Purinergic mechanisms in breast cancer support intravasation, extravasation and angiogenesis. Cancer Lett 291:131-41.
-
(2010)
Cancer Lett
, vol.291
, pp. 131-141
-
-
Buxton, I.L.1
Yokdang, N.2
Matz, R.M.3
-
43
-
-
77049116036
-
Pediatric neurological syndromes and inborn errors of purine metabolism
-
Camici M, Micheli V, Ipata PL, et al. (2010). Pediatric neurological syndromes and inborn errors of purine metabolism. Neurochem Int 56:367-78.
-
(2010)
Neurochem Int
, vol.56
, pp. 367-378
-
-
Camici, M.1
Micheli, V.2
Ipata, P.L.3
-
44
-
-
0030024822
-
Identification of a nucleotide pyrophosphohydrolase from articular tissues in human serum
-
Cardenal A, Masuda I, Haas AL, et al. (1996). Identification of a nucleotide pyrophosphohydrolase from articular tissues in human serum. Arthritis Rheum 39:252-6.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 252-256
-
-
Cardenal, A.1
Masuda, I.2
Haas, A.L.3
-
45
-
-
33646857269
-
Ecto-F1Fo ATP synthase/F1 ATPase: Metabolic and immunological functions
-
Champagne E, Martinez LO, Collet X, et al. (2006). Ecto-F1Fo ATP synthase/F1 ATPase: metabolic and immunological functions. Curr Opin Lipidol 17:279-84.
-
(2006)
Curr Opin Lipidol
, vol.17
, pp. 279-284
-
-
Champagne, E.1
Martinez, L.O.2
Collet, X.3
-
46
-
-
77956472968
-
Tartrate-resistant acid phosphatase isoform 5b (TRACP 5b) as a serum maker for cancer with bone metastasis
-
Chao TY, Wu YY, Janckila AJ. (2010). Tartrate-resistant acid phosphatase isoform 5b (TRACP 5b) as a serum maker for cancer with bone metastasis. Clin Chim Acta 411:1553-64.
-
(2010)
Clin Chim Acta
, vol.411
, pp. 1553-1564
-
-
Chao, T.Y.1
Wu, Y.Y.2
Janckila, A.J.3
-
47
-
-
0030474864
-
Inhibition of ecto-ATPase by PPADS, suramin and reactive blue in endothelial cells, C6 glioma cells and RAW 264
-
Chen BC, Lee CM, Lin WW. (1996). Inhibition of ecto-ATPase by PPADS, suramin and reactive blue in endothelial cells, C6 glioma cells and RAW 264.7 macrophages. Br J Pharmacol 119:1628-34.
-
(1996)
7 Macrophages. Br J Pharmacol
, vol.119
, pp. 1628-1634
-
-
Chen, B.C.1
Lee, C.M.2
Lin, W.W.3
-
48
-
-
84875700546
-
Adenosine receptors as drug targets-what are the challenges?
-
Chen JF, Eltzschig HK, Fredholm BB. (2013). Adenosine receptors as drug targets-what are the challenges?. Nat Rev Drug Discov 12: 265-86.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 265-286
-
-
Chen, J.F.1
Eltzschig, H.K.2
Fredholm, B.B.3
-
49
-
-
0031021476
-
Autotaxin is an exoenzyme possessing 50-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities
-
Clair T, Lee HY, Liotta LA, et al. (1997). Autotaxin is an exoenzyme possessing 50-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities. J Biol Chem 272:996-1001.
-
(1997)
J Biol Chem
, vol.272
, pp. 996-1001
-
-
Clair, T.1
Lee, H.Y.2
Liotta, L.A.3
-
50
-
-
79960516623
-
Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production
-
Clayton A, Al-Taei S, Webber J, et al. (2011). Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production. J Immunol 187:676-83.
-
(2011)
J Immunol
, vol.187
, pp. 676-683
-
-
Clayton, A.1
Al-Taei, S.2
Webber, J.3
-
51
-
-
0024455052
-
Metabolism of adenine nucleotides in human blood
-
Coade SB, Pearson JD. (1989). Metabolism of adenine nucleotides in human blood. Circ Res 65:531-7.
-
(1989)
Circ Res
, vol.65
, pp. 531-537
-
-
Coade, S.B.1
Pearson, J.D.2
-
52
-
-
79955950645
-
Activation and regulation of purinergic P2X receptor channels
-
Coddou C, Yan Z, Obsil T, et al. (2011). Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev 63:641-83.
-
(2011)
Pharmacol Rev
, vol.63
, pp. 641-683
-
-
Coddou, C.1
Yan, Z.2
Obsil, T.3
-
53
-
-
0034004075
-
Immunodeficiency caused by purine nucleoside phosphorylase deficiency
-
In: Roifman CM, ed WB Saunders Company. Philadelphia (PA)
-
Cohen A, Grunebaum E, Arpaia E, et al. (2000). Immunodeficiency caused by purine nucleoside phosphorylase deficiency. In: Roifman CM, ed. Immunology and allergy clinics of North America. Philadelphia (PA): WB Saunders Company, 143-59.
-
(2000)
Immunology and Allergy Clinics of North America
, pp. 143-159
-
-
Cohen, A.1
Grunebaum, E.2
Arpaia, E.3
-
54
-
-
33947225356
-
Physiological roles for ecto-50-nucleotidase (CD73)
-
Colgan SP, Eltzschig HK, Eckle T, et al. (2006). Physiological roles for ecto-50-nucleotidase (CD73). Purinergic Signal 2:351-60.
-
(2006)
Purinergic Signal
, vol.2
, pp. 351-360
-
-
Colgan, S.P.1
Eltzschig, H.K.2
Eckle, T.3
-
55
-
-
77951638914
-
Basal release of ATP: An autocrineparacrine mechanism for cell regulation
-
Corriden R, Insel PA. (2010). Basal release of ATP: an autocrineparacrine mechanism for cell regulation. Sci Signal 3:re1.
-
(2010)
Sci Signal
, vol.3
, pp. re1
-
-
Corriden, R.1
Insel, P.A.2
-
56
-
-
0028871207
-
Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase
-
Crack BE, Pollard CE, Beukers MW, et al. (1995). Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase. Br J Pharmacol 114:475-81.
-
(1995)
Br J Pharmacol
, vol.114
, pp. 475-481
-
-
Crack, B.E.1
Pollard, C.E.2
Beukers, M.W.3
-
57
-
-
84856237794
-
Measurement of purine release with microelectrode biosensors
-
Dale N, Frenguelli BG. (2012). Measurement of purine release with microelectrode biosensors. Purinergic Signal 8:27-40.
-
(2012)
Purinergic Signal
, vol.8
, pp. 27-40
-
-
Dale, N.1
Frenguelli, B.G.2
-
58
-
-
0015993319
-
Ecto-enzyme of granulocytes: 50-nucleotidase
-
DePierre JW, Karnovsky ML. (1974a). Ecto-enzyme of granulocytes: 50-nucleotidase. Science 183:1096-8.
-
(1974)
Science
, vol.183
, pp. 1096-1098
-
-
Depierre, J.W.1
Karnovsky, M.L.2
-
59
-
-
0016261604
-
Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. I. Evidence for an ecto-adenosine monophosphatase, adenosine triphosphatase, and -p-nitrophenyl phosphates
-
DePierre JW, Karnovsky ML. (1974b). Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. I. Evidence for an ecto-adenosine monophosphatase, adenosine triphosphatase, and -p-nitrophenyl phosphates. J Biol Chem 249:7111-20.
-
(1974)
J Biol Chem
, vol.249
, pp. 7111-7120
-
-
Depierre, J.W.1
Karnovsky, M.L.2
-
61
-
-
0036007312
-
Secreted and cellassociated adenylate kinase and nucleoside diphosphokinase contribute to extracellular nucleotide metabolism on human airway surfaces
-
Donaldson SH, Picher M, Boucher RC. (2002). Secreted and cellassociated adenylate kinase and nucleoside diphosphokinase contribute to extracellular nucleotide metabolism on human airway surfaces. Am J Respir Cell Mol Biol 26:209-15.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 209-215
-
-
Donaldson, S.H.1
Picher, M.2
Boucher, R.C.3
-
62
-
-
85047692190
-
Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation
-
Dwyer KM, Robson SC, Nandurkar HH, et al. (2004). Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation. J Clin Invest 113:1440-6.
-
(2004)
J Clin Invest
, vol.113
, pp. 1440-1446
-
-
Dwyer, K.M.1
Robson, S.C.2
Nandurkar, H.H.3
-
63
-
-
67149111580
-
Adenylate kinase and AMP signaling networks: Metabolic monitoring, signal communication and body energy sensing
-
Dzeja P, Terzic A. (2009). Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing. Int J Mol Sci 10:1729-72.
-
(2009)
Int J Mol Sci
, vol.10
, pp. 1729-1772
-
-
Dzeja, P.1
Terzic, A.2
-
64
-
-
84889281594
-
-
In: Saks V, ed. Molecular system bioenergetics. Weinheim: Wiley-VCH
-
Dzeja PP, Chung S, Terzic A. (2007). Integration of adenylate kinase, glycolytic and glycogenolytic circuits in cellular energetics. In: Saks V, ed. Molecular system bioenergetics. Weinheim: Wiley-VCH, 265-302.
-
(2007)
Integration of Adenylate Kinase, Glycolytic and Glycogenolytic Circuits in Cellular Energetics
, pp. 265-302
-
-
Dzeja, P.P.1
Chung, S.2
Terzic, A.3
-
65
-
-
34250155915
-
Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury
-
Eckle T, Fullbier L, Wehrmann M, et al. (2007a). Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury. J Immunol 178:8127-37.
-
(2007)
J Immunol
, vol.178
, pp. 8127-8137
-
-
Eckle, T.1
Fullbier, L.2
Wehrmann, M.3
-
66
-
-
34247343418
-
Cardioprotection by ecto-50- nucleotidase (CD73) and A2B adenosine receptors
-
Eckle T, Krahn T, Grenz A, et al. (2007b). Cardioprotection by ecto-50- nucleotidase (CD73) and A2B adenosine receptors. Circulation 115: 1581-90.
-
(2007)
Circulation
, vol.115
, pp. 1581-1590
-
-
Eckle, T.1
Krahn, T.2
Grenz, A.3
-
67
-
-
72249089979
-
Nucleoside-50- monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-50-nucleotidase
-
El-Tayeb A, Iqbal J, Behrenswerth A, et al. (2009). Nucleoside-50- monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-50-nucleotidase. J Med Chem 52:7669-77.
-
(2009)
J Med Chem
, vol.52
, pp. 7669-7677
-
-
El-Tayeb, A.1
Iqbal, J.2
Behrenswerth, A.3
-
68
-
-
84895465707
-
Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy
-
Elkan PN, Pierce SB, Segel R, et al. (2014). Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy. N Engl J Med 370:921-31.
-
(2014)
N Engl J Med
, vol.370
, pp. 921-931
-
-
Elkan, P.N.1
Pierce, S.B.2
Segel, R.3
-
70
-
-
0345540629
-
Targeted disruption of cd39/ ATP diphosphohydrolase results in disordered hemostasis and thromboregulation
-
Enjyoji K, Sevigny J, Lin Y, et al. (1999). Targeted disruption of cd39/ ATP diphosphohydrolase results in disordered hemostasis and thromboregulation. Nat Med 5:1010-17.
-
(1999)
Nat Med
, vol.5
, pp. 1010-1017
-
-
Enjyoji, K.1
Sevigny, J.2
Lin, Y.3
-
71
-
-
38549129745
-
P2 receptors in cardiovascular regulation and disease
-
Erlinge D, Burnstock G. (2008). P2 receptors in cardiovascular regulation and disease. Purinergic Signal 4:1-20.
-
(2008)
Purinergic Signal
, vol.4
, pp. 1-20
-
-
Erlinge, D.1
Burnstock, G.2
-
72
-
-
33845485838
-
Cell surface adenylate kinase activity regulates the F(1)-ATPase/P2Y(13)- mediated HDL endocytosis pathway on human hepatocytes
-
Fabre ACS, Vantourout P, Champagne E, et al. (2006). Cell surface adenylate kinase activity regulates the F(1)-ATPase/P2Y(13)- mediated HDL endocytosis pathway on human hepatocytes. Cell Mol Life Sci 63:2829-37.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 2829-2837
-
-
Fabre, A.C.S.1
Vantourout, P.2
Champagne, E.3
-
73
-
-
84857370202
-
Molecular mechanism and structural basis of interactions of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator
-
Fan H, Tansi FL, Weihofen WA, et al. (2012). Molecular mechanism and structural basis of interactions of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator. Eur J Cell Biol 91:265-73.
-
(2012)
Eur J Cell Biol
, vol.91
, pp. 265-273
-
-
Fan, H.1
Tansi, F.L.2
Weihofen, W.A.3
-
74
-
-
77955984138
-
Advances in capillary electrophoretic enzyme assays
-
Fan Y, Scriba GK. (2010). Advances in capillary electrophoretic enzyme assays. J Pharm Biomed Anal 53:1076-90.
-
(2010)
J Pharm Biomed Anal
, vol.53
, pp. 1076-1090
-
-
Fan, Y.1
Scriba, G.K.2
-
75
-
-
33947319312
-
Cloning, purification, and identification of the liver canalicular ecto-ATPase as NTPDase8
-
Fausther M, Lecka J, Kukulski F, et al. (2007). Cloning, purification, and identification of the liver canalicular ecto-ATPase as NTPDase8. Am J Physiol Gastrointest Liver Physiol 292:G785-95.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
, pp. G785-G795
-
-
Fausther, M.1
Lecka, J.2
Kukulski, F.3
-
76
-
-
84856742916
-
Coexpression of ecto-50- nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver
-
Fausther M, Lecka J, Soliman E, et al. (2012). Coexpression of ecto-50- nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver. Am J Physiol Gastrointest Liver Physiol 302:G447-59.
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
, pp. G447-G459
-
-
Fausther, M.1
Lecka, J.2
Soliman, E.3
-
77
-
-
79952414321
-
Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate
-
Feng L, Sun X, Csizmadia E, et al. (2011). Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate. Neoplasia 13:206-16.
-
(2011)
Neoplasia
, vol.13
, pp. 206-216
-
-
Feng, L.1
Sun, X.2
Csizmadia, E.3
-
78
-
-
0000154206
-
The colorimetric determination of phosphorus
-
Fiske CH, Subbarow Y. (1925). The colorimetric determination of phosphorus. J Biol Chem 66:375-400.
-
(1925)
J Biol Chem
, vol.66
, pp. 375-400
-
-
Fiske, C.H.1
Subbarow, Y.2
-
79
-
-
84864881916
-
Selective activation of adenosine A2A receptors on immune cells by a CD73-dependent prodrug suppresses joint inflammation in experimental rheumatoid arthritis
-
Flogel U, Burghoff S, van Lent PL, et al. (2012). Selective activation of adenosine A2A receptors on immune cells by a CD73-dependent prodrug suppresses joint inflammation in experimental rheumatoid arthritis. Sci Transl Med 4:146ra108.
-
(2012)
Sci Transl Med
, vol.4
, pp. 146ra108
-
-
Flogel, U.1
Burghoff, S.2
Van Lent, P.L.3
-
80
-
-
38049014318
-
Enzymatic and extraenzymatic role of adenosine deaminase 1 in T-cell-dendritic cell contacts and in alterations of the immune function
-
Franco R, Pacheco R, Gatell JM, et al. (2007). Enzymatic and extraenzymatic role of adenosine deaminase 1 in T-cell-dendritic cell contacts and in alterations of the immune function. Crit Rev Immunol 27:495-509.
-
(2007)
Crit Rev Immunol
, vol.27
, pp. 495-509
-
-
Franco, R.1
Pacheco, R.2
Gatell, J.M.3
-
81
-
-
79952033865
-
International union of basic and clinical pharmacology. LXXXI. Nomenclature and classification of adenosine receptors-an update
-
Fredholm BB, AP IJ, Jacobson KA, et al. (2011). International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors-an update. Pharmacol Rev 63:1-34.
-
(2011)
Pharmacol Rev
, vol.63
, pp. 1-34
-
-
Fredholm, B.B.1
-
82
-
-
84888254496
-
A new, sensitive ecto-50-nucleotidase assay for compound screening
-
Freundlieb M, Zimmermann H, Muller CE. (2013). A new, sensitive ecto-50-nucleotidase assay for compound screening. Anal Biochem 446C:53-8.
-
(2013)
Anal Biochem
, vol.446 C
, pp. 53-58
-
-
Freundlieb, M.1
Zimmermann, H.2
Muller, C.E.3
-
83
-
-
70349745514
-
From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease
-
Friedman DJ, Kunzli BM, YI AR, et al. (2009). From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease. Proc Natl Acad Sci USA 106:16788-93.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16788-16793
-
-
Friedman, D.J.1
Kunzli, B.M.2
-
84
-
-
0033304931
-
A soluble PC-1 circulates in human plasma: Relationship with insulin resistance and associated abnormalities
-
Frittitta L, Camastra S, Baratta R, et al. (1999). A soluble PC-1 circulates in human plasma: relationship with insulin resistance and associated abnormalities. J Clin Endocrinol Metab 84:3620-5.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 3620-3625
-
-
Frittitta, L.1
Camastra, S.2
Baratta, R.3
-
85
-
-
79952071002
-
A novel mechanism of gamma/delta T-lymphocyte and endothelial activation by shear stress: The role of ecto-ATP synthase beta chain
-
Fu Y, Hou Y, Fu C, et al. (2011). A novel mechanism of gamma/delta T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase beta chain. Circ Res 108:410-17.
-
(2011)
Circ Res
, vol.108
, pp. 410-417
-
-
Fu, Y.1
Hou, Y.2
Fu, C.3
-
86
-
-
84939886250
-
CD73-TNAP crosstalk regulates the hypertrophic response and cardiomyocyte calcification due to alpha1 adrenoceptor activation
-
Gan XT, Taniai S, Zhao G, et al. (2014). CD73-TNAP crosstalk regulates the hypertrophic response and cardiomyocyte calcification due to alpha1 adrenoceptor activation. Mol Cell Biochem 394:237-46.
-
(2014)
Mol Cell Biochem
, vol.394
, pp. 237-246
-
-
Gan, X.T.1
Taniai, S.2
Zhao, G.3
-
87
-
-
0018384651
-
A rapid and sensitive fluorimetric assay for adenosine, inosine, and hypoxanthine
-
Gardiner DG. (1979). A rapid and sensitive fluorimetric assay for adenosine, inosine, and hypoxanthine. Anal Biochem 95:377-82.
-
(1979)
Anal Biochem
, vol.95
, pp. 377-382
-
-
Gardiner, D.G.1
-
88
-
-
0037434917
-
The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site
-
Gijsbers R, Aoki J, Arai H, et al. (2003). The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site. FEBS Lett 538:60-4.
-
(2003)
FEBS Lett
, vol.538
, pp. 60-64
-
-
Gijsbers, R.1
Aoki, J.2
Arai, H.3
-
89
-
-
84859882118
-
Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection
-
Giuliani P, Ballerini P, Ciccarelli R, et al. (2012). Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection. J Biol Regul Homeost Agents 26:51-65.
-
(2012)
J Biol Regul Homeost Agents
, vol.26
, pp. 51-65
-
-
Giuliani, P.1
Ballerini, P.2
Ciccarelli, R.3
-
90
-
-
0038664247
-
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/ phosphodiesterase family
-
Goding JW, Grobben B, Slegers H. (2003). Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/ phosphodiesterase family. Biochim Biophys Acta 1638:1-19.
-
(2003)
Biochim Biophys Acta
, vol.1638
, pp. 1-19
-
-
Goding, J.W.1
Grobben, B.2
Slegers, H.3
-
91
-
-
0035910015
-
Disordered cellular migration and angiogenesis in cd39-null mice
-
Goepfert C, Sundberg C, Sevigny J, et al. (2001). Disordered cellular migration and angiogenesis in cd39-null mice. Circulation 104: 3109-15.
-
(2001)
Circulation
, vol.104
, pp. 3109-3115
-
-
Goepfert, C.1
Sundberg, C.2
Sevigny, J.3
-
93
-
-
34548477422
-
Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury
-
Grenz A, Zhang H, Hermes M, et al. (2007). Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury. FASEB J 21:2863-73.
-
(2007)
FASEB J
, vol.21
, pp. 2863-2873
-
-
Grenz, A.1
Zhang, H.2
Hermes, M.3
-
94
-
-
0032902151
-
An ecto-nucleotide pyrophosphatase is one of the main enzymes involved in the extracellular metabolism of ATP in rat C6 glioma
-
Grobben B, Anciaux K, Roymans D, et al. (1999). An ecto-nucleotide pyrophosphatase is one of the main enzymes involved in the extracellular metabolism of ATP in rat C6 glioma. J Neurochem 72: 826-34.
-
(1999)
J Neurochem
, vol.72
, pp. 826-834
-
-
Grobben, B.1
Anciaux, K.2
Roymans, D.3
-
95
-
-
84878065302
-
Nucleotides in the eye: Focus on functional aspects and therapeutic perspectives
-
Guzman-Aranguez A, Santano C, Martin-Gil A, et al. (2013). Nucleotides in the eye: focus on functional aspects and therapeutic perspectives. J Pharmacol Exp Ther 345:331-41.
-
(2013)
J Pharmacol Exp Ther
, vol.345
, pp. 331-341
-
-
Guzman-Aranguez, A.1
Santano, C.2
Martin-Gil, A.3
-
96
-
-
58149379886
-
Ecto-50 nucleotidase (CD73)-mediated adenosine generation and signaling in murine cardiac allograft vasculopathy
-
Hasegawa T, Bouis D, Liao H, et al. (2008). Ecto-50 nucleotidase (CD73)-mediated adenosine generation and signaling in murine cardiac allograft vasculopathy. Circ Res 103:1410-21.
-
(2008)
Circ Res
, vol.103
, pp. 1410-1421
-
-
Hasegawa, T.1
Bouis, D.2
Liao, H.3
-
97
-
-
84867745449
-
Outcome of hematopoietic stem cell transplantation for adenosine deaminasedeficient severe combined immunodeficiency
-
quiz 26
-
Hassan A, Booth C, Brightwell A, et al. (2012). Outcome of hematopoietic stem cell transplantation for adenosine deaminasedeficient severe combined immunodeficiency. Blood 120:3615-24; quiz 26.
-
(2012)
Blood
, vol.120
, pp. 3615-3624
-
-
Hassan, A.1
Booth, C.2
Brightwell, A.3
-
98
-
-
0029851956
-
Mice lacking tartrateresistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis
-
Hayman AR, Jones SJ, Boyde A, et al. (1996). Mice lacking tartrateresistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis. Development 122:3151-62.
-
(1996)
Development
, vol.122
, pp. 3151-3162
-
-
Hayman, A.R.1
Jones, S.J.2
Boyde, A.3
-
99
-
-
84865294285
-
Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids
-
Helenius M, Jalkanen S, Yegutkin GG. (2012). Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids. Biochim Biophys Acta 1823:1967-75.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 1967-1975
-
-
Helenius, M.1
Jalkanen, S.2
Yegutkin, G.G.3
-
100
-
-
0043092170
-
Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by Ecto-50-nucleotidase/CD73-dependent mechanism
-
Henttinen T, Jalkanen S, Yegutkin GG. (2003). Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by Ecto-50-nucleotidase/CD73-dependent mechanism. J Biol Chem 278:24888-95.
-
(2003)
J Biol Chem
, vol.278
, pp. 24888-24895
-
-
Henttinen, T.1
Jalkanen, S.2
Yegutkin, G.G.3
-
101
-
-
0037047051
-
Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization
-
Hessle L, Johnson KA, Anderson HC, et al. (2002). Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization. Proc Natl Acad Sci USA 99:9445-9.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9445-9449
-
-
Hessle, L.1
Johnson, K.A.2
Anderson, H.C.3
-
102
-
-
84868101286
-
Crystal structure of a soluble form of human CD73 with ecto-50-nucleotidase activity
-
Heuts DP, Weissenborn MJ, Olkhov RV, et al. (2012). Crystal structure of a soluble form of human CD73 with ecto-50-nucleotidase activity. Chembiochem 13:2384-91.
-
(2012)
Chembiochem
, vol.13
, pp. 2384-2391
-
-
Heuts, D.P.1
Weissenborn, M.J.2
Olkhov, R.V.3
-
103
-
-
83855160838
-
Autotaxin and LPA receptor signaling in cancer
-
Houben AJ, Moolenaar WH. (2011). Autotaxin and LPA receptor signaling in cancer. Cancer Metastasis Rev 30:557-65.
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 557-565
-
-
Houben, A.J.1
Moolenaar, W.H.2
-
104
-
-
20444368420
-
The 50-nucleotidases as regulators of nucleotide and drug metabolism
-
Hunsucker SA, Mitchell BS, Spychala J. (2005). The 50-nucleotidases as regulators of nucleotide and drug metabolism. Pharmacol Ther 107: 1-30.
-
(2005)
Pharmacol Ther
, vol.107
, pp. 1-30
-
-
Hunsucker, S.A.1
Mitchell, B.S.2
Spychala, J.3
-
105
-
-
84900530332
-
Nucleotide signalling during inflammation
-
Idzko M, Ferrari D, Eltzschig HK. (2014). Nucleotide signalling during inflammation. Nature 509:310-17.
-
(2014)
Nature
, vol.509
, pp. 310-317
-
-
Idzko, M.1
Ferrari, D.2
Eltzschig, H.K.3
-
106
-
-
84859340952
-
Origin, utilization, and recycling of nucleosides in the central nervous system
-
Ipata PL. (2011). Origin, utilization, and recycling of nucleosides in the central nervous system. Adv Physiol Educ 35:342-6.
-
(2011)
Adv Physiol Educ
, vol.35
, pp. 342-346
-
-
Ipata, P.L.1
-
107
-
-
53149092862
-
A highly sensitive CEUV method with dynamic coating of silica-fused capillaries for monitoring of nucleotide pyrophosphatase/phosphodiesterase reactions
-
Iqbal J, Levesque SA, Sevigny J, et al. (2008a). A highly sensitive CEUV method with dynamic coating of silica-fused capillaries for monitoring of nucleotide pyrophosphatase/phosphodiesterase reactions. Electrophoresis 29:3685-93.
-
(2008)
Electrophoresis
, vol.29
, pp. 3685-3693
-
-
Iqbal, J.1
Levesque, S.A.2
Sevigny, J.3
-
108
-
-
37049009485
-
Capillary electrophoresisbased nanoscale assays for monitoring ecto-50-nucleotidase activity and inhibition in preparations of recombinant enzyme and melanoma cell membranes
-
Iqbal J, Jirovsky D, Lee SY, et al. (2008b). Capillary electrophoresisbased nanoscale assays for monitoring ecto-50-nucleotidase activity and inhibition in preparations of recombinant enzyme and melanoma cell membranes. Anal Biochem 373:129-40.
-
(2008)
Anal Biochem
, vol.373
, pp. 129-140
-
-
Iqbal, J.1
Jirovsky, D.2
Lee, S.Y.3
-
109
-
-
79959551371
-
High-sensitivity capillary electrophoresis method for monitoring purine nucleoside phosphorylase and adenosine deaminase reactions by a reversed electrode polarity switching mode
-
Iqbal J, Muller CE. (2011). High-sensitivity capillary electrophoresis method for monitoring purine nucleoside phosphorylase and adenosine deaminase reactions by a reversed electrode polarity switching mode. J Chromatogr A 1218:4764-71.
-
(2011)
J Chromatogr A
, vol.1218
, pp. 4764-4771
-
-
Iqbal, J.1
Muller, C.E.2
-
110
-
-
29744434583
-
A capillary electrophoresis method for the characterization of ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) and the analysis of inhibitors by in-capillary enzymatic microreaction
-
Iqbal J, Vollmayer P, Braun N, et al. (2005). A capillary electrophoresis method for the characterization of ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) and the analysis of inhibitors by in-capillary enzymatic microreaction. Purinergic Signal 1:349-58.
-
(2005)
Purinergic Signal
, vol.1
, pp. 349-358
-
-
Iqbal, J.1
Vollmayer, P.2
Braun, N.3
-
111
-
-
35348839497
-
Disordered purinergic signaling inhibits pathological angiogenesis in cd39/Entpd1-null mice
-
Jackson SW, Hoshi T, Wu Y, et al. (2007). Disordered purinergic signaling inhibits pathological angiogenesis in cd39/Entpd1-null mice. Am J Pathol 171:1395-404.
-
(2007)
Am J Pathol
, vol.171
, pp. 1395-1404
-
-
Jackson, S.W.1
Hoshi, T.2
Wu, Y.3
-
112
-
-
33644770260
-
Adenosine receptors as therapeutic targets
-
Jacobson KA, Gao ZG. (2006). Adenosine receptors as therapeutic targets. Nat Rev Drug Discov 5:247-64.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 247-264
-
-
Jacobson, K.A.1
Gao, Z.G.2
-
113
-
-
84868572582
-
Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification
-
Jansen S, Perrakis A, Ulens C, et al. (2012). Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification. Structure 20:1948-59.
-
(2012)
Structure
, vol.20
, pp. 1948-1959
-
-
Jansen, S.1
Perrakis, A.2
Ulens, C.3
-
114
-
-
0034406524
-
Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement
-
Janssen E, Dzeja PP, Oerlemans F, et al. (2000). Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement. EMBO J 19:6371-81.
-
(2000)
EMBO J
, vol.19
, pp. 6371-6381
-
-
Janssen, E.1
Dzeja, P.P.2
Oerlemans, F.3
-
115
-
-
0037593535
-
Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes
-
Joseph SM, Buchakjian MR, Dubyak GR. (2003). Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes. J Biol Chem 278:23331-42.
-
(2003)
J Biol Chem
, vol.278
, pp. 23331-23342
-
-
Joseph, S.M.1
Buchakjian, M.R.2
Dubyak, G.R.3
-
116
-
-
79952192382
-
Immune cell regulation by autocrine purinergic signalling
-
Junger WG. (2012). Immune cell regulation by autocrine purinergic signalling. Nat Rev Immunol 11:201-12.
-
(2012)
Nat Rev Immunol
, vol.11
, pp. 201-212
-
-
Junger, W.G.1
-
117
-
-
12644288616
-
Identification and characterization of CD39/vascular ATP diphosphohydrolase
-
Kaczmarek E, Koziak K, Sevigny J, et al. (1996). Identification and characterization of CD39/vascular ATP diphosphohydrolase. J Biol Chem 271:33116-22.
-
(1996)
J Biol Chem
, vol.271
, pp. 33116-33122
-
-
Kaczmarek, E.1
Koziak, K.2
Sevigny, J.3
-
118
-
-
0342953981
-
Enzymic micro determinations of uric acid, hypoxanthine, xanthine, adenine, and xanthopterine by ultraviolet spectrophotometry
-
Kalckar HM, Plesner P. (1956). Enzymic micro determinations of uric acid, hypoxanthine, xanthine, adenine, and xanthopterine by ultraviolet spectrophotometry. Methods Biochem Anal 3:97-110.
-
(1956)
Methods Biochem Anal
, vol.3
, pp. 97-110
-
-
Kalckar, H.M.1
Plesner, P.2
-
119
-
-
40949164579
-
Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs
-
Kanda H, Newton R, Klein R, et al. (2008). Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs. Nat Immunol 9:415-23.
-
(2008)
Nat Immunol
, vol.9
, pp. 415-423
-
-
Kanda, H.1
Newton, R.2
Klein, R.3
-
120
-
-
0023227847
-
Chemiluminescent determination of adenosine, inosine, and hypoxanthine/xanthine
-
Kather H, Wieland E, Waas W. (1987). Chemiluminescent determination of adenosine, inosine, and hypoxanthine/xanthine. Anal Biochem 163: 45-51.
-
(1987)
Anal Biochem
, vol.163
, pp. 45-51
-
-
Kather, H.1
Wieland, E.2
Waas, W.3
-
121
-
-
72049103706
-
NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse
-
Kauffenstein G, Drouin A, Thorin-Trescases N, et al. (2010). NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse. Cardiovasc Res 85:204-13.
-
(2010)
Cardiovasc Res
, vol.85
, pp. 204-213
-
-
Kauffenstein, G.1
Drouin, A.2
Thorin-Trescases, N.3
-
122
-
-
54849442254
-
TNAP, TrAP, ecto-purinergic signaling, and bone remodeling
-
Kaunitz JD, Yamaguchi DT. (2008). TNAP, TrAP, ecto-purinergic signaling, and bone remodeling. J Cell Biochem 105:655-62.
-
(2008)
J Cell Biochem
, vol.105
, pp. 655-662
-
-
Kaunitz, J.D.1
Yamaguchi, D.T.2
-
123
-
-
84894597311
-
The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth
-
Kim H, Lee HJ, Oh Y, et al. (2014). The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth. Nat Commun 5:3351.
-
(2014)
Nat Commun
, vol.5
, pp. 3351
-
-
Kim, H.1
Lee, H.J.2
Oh, Y.3
-
124
-
-
84877764516
-
Evolutionary origins of taste buds: Phylogenetic analysis of purinergic neurotransmission in epithelial chemosensors
-
Kirino M, Parnes J, Hansen A, et al. (2013). Evolutionary origins of taste buds: phylogenetic analysis of purinergic neurotransmission in epithelial chemosensors. Open Biol 3:130015.
-
(2013)
Open Biol
, vol.3
, pp. 130015
-
-
Kirino, M.1
Parnes, J.2
Hansen, A.3
-
125
-
-
20244376494
-
Expression of NTPDase1 and NTPDase2 in murine kidney: Relevance to regulation of P2 receptor signaling
-
Kishore BK, Isaac J, Fausther M, et al. (2005). Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling. Am J Physiol Renal Physiol 288:F1032-43.
-
(2005)
Am J Physiol Renal Physiol
, vol.288
, pp. F1032-F1043
-
-
Kishore, B.K.1
Isaac, J.2
Fausther, M.3
-
126
-
-
37549022214
-
IFN-beta protects from vascular leakage via up-regulation of CD73
-
Kiss J, Yegutkin GG, Koskinen K, et al. (2007). IFN-beta protects from vascular leakage via up-regulation of CD73. Eur J Immunol 37: 3334-8.
-
(2007)
Eur J Immunol
, vol.37
, pp. 3334-3338
-
-
Kiss, J.1
Yegutkin, G.G.2
Koskinen, K.3
-
127
-
-
16644370948
-
Co-localization of P2Y1 receptor and NTPDase1/CD39 within caveolae in human placenta
-
Kittel A, Csapo ZS, Csizmadia E, et al. (2004a). Co-localization of P2Y1 receptor and NTPDase1/CD39 within caveolae in human placenta. Eur J Histochem 48:253-9.
-
(2004)
Eur J Histochem
, vol.48
, pp. 253-259
-
-
Kittel, A.1
Csapo, Z.S.2
Csizmadia, E.3
-
128
-
-
3042699600
-
Localization of nucleoside triphosphate diphosphohydrolase-1 (NTPDase1) and NTPDase2 in pancreas and salivary gland
-
Kittel A, Pelletier J, Bigonnesse F, et al. (2004b). Localization of nucleoside triphosphate diphosphohydrolase-1 (NTPDase1) and NTPDase2 in pancreas and salivary gland. J Histochem Cytochem 52:861-71.
-
(2004)
J Histochem Cytochem
, vol.52
, pp. 861-871
-
-
Kittel, A.1
Pelletier, J.2
Bigonnesse, F.3
-
129
-
-
84870480855
-
Crystal structure of the human ecto-50-nucleotidase (CD73): Insights into the regulation of purinergic signaling
-
Knapp K, Zebisch M, Pippel J, et al. (2012). Crystal structure of the human ecto-50-nucleotidase (CD73): insights into the regulation of purinergic signaling. Structure 20:2161-73.
-
(2012)
Structure
, vol.20
, pp. 2161-2173
-
-
Knapp, K.1
Zebisch, M.2
Pippel, J.3
-
130
-
-
79953162422
-
The GDA1-CD39 superfamily: NTPDases with diverse functions
-
Knowles AF. (2011). The GDA1-CD39 superfamily: NTPDases with diverse functions. Purinergic Signal 7:21-45.
-
(2011)
Purinergic Signal
, vol.7
, pp. 21-45
-
-
Knowles, A.F.1
-
131
-
-
37349104240
-
CD39/Ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury
-
Kohler D, Eckle T, Faigle M, et al. (2007). CD39/Ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury. Circulation 116:1784-94.
-
(2007)
Circulation
, vol.116
, pp. 1784-1794
-
-
Kohler, D.1
Eckle, T.2
Faigle, M.3
-
132
-
-
6344283049
-
Targeted disruption of cd73/ecto-50-nucleotidase alters thromboregulation and augments vascular inflammatory response [see comment]
-
Koszalka P, Ozuyaman B, Huo Y, et al. (2004). Targeted disruption of cd73/ecto-50-nucleotidase alters thromboregulation and augments vascular inflammatory response [see comment]. Circ Res 95: 814-21.
-
(2004)
Circ Res
, vol.95
, pp. 814-821
-
-
Koszalka, P.1
Ozuyaman, B.2
Huo, Y.3
-
133
-
-
16444369930
-
Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8
-
Kukulski F, Levesque SA, Lavoie EG, et al. (2005). Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8. Purinergic Signal 1:193-204.
-
(2005)
Purinergic Signal
, vol.1
, pp. 193-204
-
-
Kukulski, F.1
Levesque, S.A.2
Lavoie, E.G.3
-
134
-
-
79955954921
-
Impact of ectoenzymes on P2 and P1 receptor signaling
-
Kukulski F, Levesque SA, Sevigny J. (2011). Impact of ectoenzymes on P2 and P1 receptor signaling. Adv Pharmacol 61:263-99.
-
(2011)
Adv Pharmacol
, vol.61
, pp. 263-299
-
-
Kukulski, F.1
Levesque, S.A.2
Sevigny, J.3
-
135
-
-
84872203428
-
Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine
-
Kusu T, Kayama H, Kinoshita M, et al. (2013). Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine. J Immunol 190:774-83.
-
(2013)
J Immunol
, vol.190
, pp. 774-783
-
-
Kusu, T.1
Kayama, H.2
Kinoshita, M.3
-
136
-
-
0033804737
-
The human Nm23/ nucleoside diphosphate kinases
-
Lacombe ML, Milon L, Munier A, et al. (2000). The human Nm23/ nucleoside diphosphate kinases. J Bioenerg Biomembr 32:247-58.
-
(2000)
J Bioenerg Biomembr
, vol.32
, pp. 247-258
-
-
Lacombe, M.L.1
Milon, L.2
Munier, A.3
-
137
-
-
84893771900
-
Intestinal alkaline phosphatase: Novel functions and protective effects
-
Lalles JP. (2014). Intestinal alkaline phosphatase: novel functions and protective effects. Nutr Rev 72:82-94.
-
(2014)
Nutr Rev
, vol.72
, pp. 82-94
-
-
Lalles, J.P.1
-
138
-
-
55749087151
-
Distribution of ectonucleotidases in the rodent brain revisited
-
Langer D, Hammer K, Koszalka P, et al. (2008). Distribution of ectonucleotidases in the rodent brain revisited. Cell Tissue Res 334: 199-217.
-
(2008)
Cell Tissue Res
, vol.334
, pp. 199-217
-
-
Langer, D.1
Hammer, K.2
Koszalka, P.3
-
139
-
-
36849092887
-
The ectonucleotidases alkaline phosphatase and nucleoside triphosphate diphosphohydrolase 2 are associated with subsets of progenitor cell populations in the mouse embryonic, postnatal and adult neurogenic zones
-
Langer D, Ikehara Y, Takebayashi H, et al. (2007). The ectonucleotidases alkaline phosphatase and nucleoside triphosphate diphosphohydrolase 2 are associated with subsets of progenitor cell populations in the mouse embryonic, postnatal and adult neurogenic zones. Neuroscience 150:863-79.
-
(2007)
Neuroscience
, vol.150
, pp. 863-879
-
-
Langer, D.1
Ikehara, Y.2
Takebayashi, H.3
-
140
-
-
0018600707
-
An improved assay for nanomole amounts of inorganic phosphate
-
Lanzetta PA, Alvarez LJ, Reinach PS, et al. (1979). An improved assay for nanomole amounts of inorganic phosphate. Anal Biochem 100: 95-7.
-
(1979)
Anal Biochem
, vol.100
, pp. 95-97
-
-
Lanzetta, P.A.1
Alvarez, L.J.2
Reinach, P.S.3
-
141
-
-
77957567329
-
Identification of the ectonucleotidases expressed in mouse, rat, and human Langerhans islets: Potential role of NTPDase3 in insulin secretion
-
Lavoie EG, Fausther M, Kauffenstein G, et al. (2010). Identification of the ectonucleotidases expressed in mouse, rat, and human Langerhans islets: potential role of NTPDase3 in insulin secretion. Am J Physiol Endocrinol Metab 299:E647-56.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, pp. E647-E656
-
-
Lavoie, E.G.1
Fausther, M.2
Kauffenstein, G.3
-
143
-
-
84861532159
-
Vesicular and conductive mechanisms of nucleotide release
-
Lazarowski ER. (2012). Vesicular and conductive mechanisms of nucleotide release. Purinergic Signal 8:359-73.
-
(2012)
Purinergic Signal
, vol.8
, pp. 359-373
-
-
Lazarowski, E.R.1
-
144
-
-
0034613299
-
Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations
-
Lazarowski ER, Boucher RC, Harden TK. (2000). Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations. J Biol Chem 275:31061-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 31061-31068
-
-
Lazarowski, E.R.1
Boucher, R.C.2
Harden, T.K.3
-
145
-
-
0030760291
-
Identification of an ecto-nucleoside diphosphokinase and its contribution to interconversion of P2 receptor agonists
-
Lazarowski ER, Homolya L, Boucher RC, et al. (1997). Identification of an ecto-nucleoside diphosphokinase and its contribution to interconversion of P2 receptor agonists. J Biol Chem 272:20402-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 20402-20407
-
-
Lazarowski, E.R.1
Homolya, L.2
Boucher, R.C.3
-
146
-
-
4344619319
-
Nucleotide release provides a mechanism for airway surface liquid homeostasis
-
Lazarowski ER, Tarran R, Grubb BR, et al. (2004). Nucleotide release provides a mechanism for airway surface liquid homeostasis. J Biol Chem 279:36855-64.
-
(2004)
J Biol Chem
, vol.279
, pp. 36855-36864
-
-
Lazarowski, E.R.1
Tarran, R.2
Grubb, B.R.3
-
147
-
-
35748962612
-
AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10
-
Lee HJ, Pyo JO, Oh Y, et al. (2007). AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10. Nat Cell Biol 9:1303-10.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1303-1310
-
-
Lee, H.J.1
Pyo, J.O.2
Oh, Y.3
-
148
-
-
84870523266
-
A highly sensitive capillary electrophoresis method using p-nitrophenyl 50-thymidine monophosphate as a substrate for the monitoring of nucleotide pyrophosphatase/phosphodiesterase activities
-
Lee SY, Levesque SA, Sevigny J, et al. (2012). A highly sensitive capillary electrophoresis method using p-nitrophenyl 50-thymidine monophosphate as a substrate for the monitoring of nucleotide pyrophosphatase/phosphodiesterase activities. J Chromatogr B Analyt Technol Biomed Life Sci 911:162-9.
-
(2012)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.911
, pp. 162-169
-
-
Lee, S.Y.1
Levesque, S.A.2
Sevigny, J.3
-
149
-
-
84903368421
-
Large-volume sample stacking with polarity switching for monitoring of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) reactions by capillary electrophoresis
-
Lee SY, Muller CE. (2014). Large-volume sample stacking with polarity switching for monitoring of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) reactions by capillary electrophoresis. Electrophoresis 35:855-63.
-
(2014)
Electrophoresis
, vol.35
, pp. 855-863
-
-
Lee, S.Y.1
Muller, C.E.2
-
150
-
-
0032524568
-
Release of the glycosylphosphatidylinositol- anchored enzyme ecto-50-nucleotidase by phospholipase C: Catalytic activation and modulation by the lipid bilayer
-
Lehto MT, Sharom FJ. (1998). Release of the glycosylphosphatidylinositol- anchored enzyme ecto-50-nucleotidase by phospholipase C: catalytic activation and modulation by the lipid bilayer. Biochem J 332:101-9.
-
(1998)
Biochem J
, vol.332
, pp. 101-109
-
-
Lehto, M.T.1
Sharom, F.J.2
-
151
-
-
84866492972
-
Mechanisms of ATP release and signalling in the blood vessel wall
-
Lohman AW, Billaud M, Isakson BE. (2012). Mechanisms of ATP release and signalling in the blood vessel wall. Cardiovasc Res 95: 269-80.
-
(2012)
Cardiovasc Res
, vol.95
, pp. 269-280
-
-
Lohman, A.W.1
Billaud, M.2
Isakson, B.E.3
-
152
-
-
84921538360
-
Increased intravitreal adenosine 50-triphosphate, adenosine 50-diphosphate and adenosine 50- monophosphate levels in patients with proliferative diabetic retinopathy
-
[in press]
-
Loukovaara S, Sahanne S, Jalkanen S, et al. (2014). Increased intravitreal adenosine 50-triphosphate, adenosine 50-diphosphate and adenosine 50- monophosphate levels in patients with proliferative diabetic retinopathy. Acta Ophthalmol. doi: 10.1111/aos.12507 [in press].
-
(2014)
Acta Ophthalmol
-
-
Loukovaara, S.1
Sahanne, S.2
Jalkanen, S.3
-
153
-
-
84867049936
-
New insights into NPP1 function: Lessons from clinical and animal studies
-
Mackenzie NC, Huesa C, Rutsch F, et al. (2012). New insights into NPP1 function: lessons from clinical and animal studies. Bone 51:961-8.
-
(2012)
Bone
, vol.51
, pp. 961-968
-
-
Mackenzie, N.C.1
Huesa, C.2
Rutsch, F.3
-
154
-
-
84867052003
-
CD73-generated adenosine facilitates Toxoplasma gondii differentiation to long-lived tissue cysts in the central nervous system
-
Mahamed DA, Mills JH, Egan CE, et al. (2012). CD73-generated adenosine facilitates Toxoplasma gondii differentiation to long-lived tissue cysts in the central nervous system. Proc Natl Acad Sci USA 109:16312-17.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 16312-16317
-
-
Mahamed, D.A.1
Mills, J.H.2
Egan, C.E.3
-
155
-
-
84922554504
-
Early prediction of persistent organ failure by soluble CD73 in patients with acute pancreatitis
-
Maksimow M, Kyhäla L, Nieminen A, et al. (2014). Early prediction of persistent organ failure by soluble CD73 in patients with acute pancreatitis. Crit Care Med 42:2556-64.
-
(2014)
Crit Care Med
, vol.42
, pp. 2556-2564
-
-
Maksimow, M.1
Kyhäla, L.2
Nieminen, A.3
-
156
-
-
35548943233
-
Purine-mediated signalling triggers eye development
-
Masse K, Bhamra S, Eason R, et al. (2007). Purine-mediated signalling triggers eye development. Nature 449:1058-62.
-
(2007)
Nature
, vol.449
, pp. 1058-1062
-
-
Masse, K.1
Bhamra, S.2
Eason, R.3
-
157
-
-
84861526979
-
Purines as potential morphogens during embryonic development
-
Masse K, Dale N. (2012). Purines as potential morphogens during embryonic development. Purinergic Signal 8:503-21.
-
(2012)
Purinergic Signal
, vol.8
, pp. 503-521
-
-
Masse, K.1
Dale, N.2
-
158
-
-
83455228676
-
Impaired ATPinduced coronary blood flow and diminished aortic NTPDase activity precede lesion formation in apolipoprotein E-deficient mice
-
Mercier N, Kiviniemi TO, Saraste A, et al. (2012). Impaired ATPinduced coronary blood flow and diminished aortic NTPDase activity precede lesion formation in apolipoprotein E-deficient mice. Am J Pathol 180:419-28.
-
(2012)
Am J Pathol
, vol.180
, pp. 419-428
-
-
Mercier, N.1
Kiviniemi, T.O.2
Saraste, A.3
-
159
-
-
41849134386
-
Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling
-
Mi T, Abbasi S, Zhang H, et al. (2008). Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling. J Clin Invest 118:1491-501.
-
(2008)
J Clin Invest
, vol.118
, pp. 1491-1501
-
-
Mi, T.1
Abbasi, S.2
Zhang, H.3
-
160
-
-
83755181759
-
Autophagydependent anticancer immune responses induced by chemotherapeutic agents in mice
-
Michaud M, Martins I, Sukkurwala AQ, et al. (2011). Autophagydependent anticancer immune responses induced by chemotherapeutic agents in mice. Science 334:1573-7.
-
(2011)
Science
, vol.334
, pp. 1573-1577
-
-
Michaud, M.1
Martins, I.2
Sukkurwala, A.Q.3
-
161
-
-
34250160114
-
Alkaline phosphatases. Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes
-
Millan J. (2006a). Alkaline phosphatases. Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes. Purinergic Signal 2:335-41.
-
(2006)
Purinergic Signal
, vol.2
, pp. 335-341
-
-
Millan, J.1
-
163
-
-
0036102125
-
CD39 is the dominant Langerhans cell-associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness
-
Mizumoto N, Kumamoto T, Robson SC, et al. (2002). CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness. Nat Med 8: 358-65.
-
(2002)
Nat Med
, vol.8
, pp. 358-365
-
-
Mizumoto, N.1
Kumamoto, T.2
Robson, S.C.3
-
164
-
-
80053131258
-
Insights into autotaxin: How to produce and present a lipid mediator
-
Moolenaar WH, Perrakis A. (2011). Insights into autotaxin: how to produce and present a lipid mediator. Nat Rev Mol Cell Biol 12: 674-9.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 674-679
-
-
Moolenaar, W.H.1
Perrakis, A.2
-
165
-
-
0032851248
-
Enzymes involved in purine metabolism -A review of histochemical localization and functional implications
-
Moriwaki Y, Yamamoto T, Higashino K. (1999). Enzymes involved in purine metabolism -a review of histochemical localization and functional implications. Histol Histopathol 14:1321-40.
-
(1999)
Histol Histopathol
, vol.14
, pp. 1321-1340
-
-
Moriwaki, Y.1
Yamamoto, T.2
Higashino, K.3
-
166
-
-
0037333434
-
Specific increase in enzymatic activity of adenosine deaminase 1 in rheumatoid synovial fibroblasts
-
Nakamachi Y, Koshiba M, Nakazawa T, et al. (2003). Specific increase in enzymatic activity of adenosine deaminase 1 in rheumatoid synovial fibroblasts. Arthritis Rheum 48:668-74.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 668-674
-
-
Nakamachi, Y.1
Koshiba, M.2
Nakazawa, T.3
-
167
-
-
0142059930
-
Accelerated fat absorption in intestinal alkaline phosphatase knockout mice
-
Narisawa S, Huang L, Iwasaki A, et al. (2003). Accelerated fat absorption in intestinal alkaline phosphatase knockout mice. Mol Cell Biol 23:7525-30.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7525-7530
-
-
Narisawa, S.1
Huang, L.2
Iwasaki, A.3
-
168
-
-
58149250587
-
IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier
-
Niemela J, Ifergan I, Yegutkin GG, et al. (2008). IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier. Eur J Immunol 38:2718-26.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2718-2726
-
-
Niemela, J.1
Ifergan, I.2
Yegutkin, G.G.3
-
169
-
-
0015968725
-
Quantitative thin-layer chromatography of ATP and the products of its degradation in meat tissue
-
Norman GA, Follett MJ, Hector DA. (1974). Quantitative thin-layer chromatography of ATP and the products of its degradation in meat tissue. J Chromatogr 90:105-11.
-
(1974)
J Chromatogr
, vol.90
, pp. 105-111
-
-
Norman, G.A.1
Follett, M.J.2
Hector, D.A.3
-
170
-
-
84874395522
-
Ecto-50-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase
-
Ohta M, Toyama K, Gutterman DD, et al. (2013). Ecto-50-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase. Arterioscler Thromb Vasc Biol 33:629-36.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 629-636
-
-
Ohta, M.1
Toyama, K.2
Gutterman, D.D.3
-
171
-
-
0031859977
-
Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine
-
Okawa A, Nakamura I, Goto S, et al. (1998). Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine. Nat Genet 19:271-3.
-
(1998)
Nat Genet
, vol.19
, pp. 271-273
-
-
Okawa, A.1
Nakamura, I.2
Goto, S.3
-
172
-
-
82955207195
-
ATP synthase ecto-alphasubunit: A novel therapeutic target for breast cancer
-
Pan J, Sun LC, Tao YF, et al. (2011). ATP synthase ecto-alphasubunit: a novel therapeutic target for breast cancer. J Transl Med 9: 211. doi: 10.1186/1479-5876-9-211.
-
(2011)
J Transl Med
, vol.9
, pp. 211
-
-
Pan, J.1
Sun, L.C.2
Tao, Y.F.3
-
174
-
-
58149142930
-
Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2
-
Pannicke U, Honig M, Hess I, et al. (2009). Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2. Nat Genet 41:101-5.
-
(2009)
Nat Genet
, vol.41
, pp. 101-105
-
-
Pannicke, U.1
Honig, M.2
Hess, I.3
-
177
-
-
0019139761
-
Metabolism of adenine nucleotides by ectoenzymes of vascular endothelial and smoothmuscle cells in culture
-
Pearson JD, Carleton JS, Gordon JL. (1980). Metabolism of adenine nucleotides by ectoenzymes of vascular endothelial and smoothmuscle cells in culture. Biochem J 190:421-9.
-
(1980)
Biochem J
, vol.190
, pp. 421-429
-
-
Pearson, J.D.1
Carleton, J.S.2
Gordon, J.L.3
-
178
-
-
67651172779
-
Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates
-
Pelegrin P, Surprenant A. (2009). Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates. EMBO J 28:2114-27.
-
(2009)
EMBO J
, vol.28
, pp. 2114-2127
-
-
Pelegrin, P.1
Surprenant, A.2
-
179
-
-
50249085890
-
Increased level of extracellular ATP at tumor sites: In vivo imaging with plasma membrane luciferase
-
Pellegatti P, Raffaghello L, Bianchi G, et al. (2008). Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase. PLoS One 3:e2599.
-
(2008)
PLoS One
, vol.3
, pp. e2599
-
-
Pellegatti, P.1
Raffaghello, L.2
Bianchi, G.3
-
180
-
-
84884571678
-
Soluble ecto-50- nucleotidase (50-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine
-
Pettengill M, Robson S, Tresenriter M, et al. (2013). Soluble ecto-50- nucleotidase (50-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine. J Biol Chem 288:27315-26.
-
(2013)
J Biol Chem
, vol.288
, pp. 27315-27326
-
-
Pettengill, M.1
Robson, S.2
Tresenriter, M.3
-
181
-
-
0038514195
-
Human Airway Ecto-adenylate Kinase. A mechanism to propagate atp signaling on airway surfaces
-
Picher M, Boucher RC. (2003). Human Airway Ecto-adenylate Kinase. A mechanism to propagate atp signaling on airway surfaces. J Biol Chem 278:11256-64.
-
(2003)
J Biol Chem
, vol.278
, pp. 11256-11264
-
-
Picher, M.1
Boucher, R.C.2
-
183
-
-
84882799443
-
A novel hypothesis for an alkaline phosphatase 'rescue' mechanism in the hepatic acute phase immune response
-
Pike AF, Kramer NI, Blaauboer BJ, et al. (2013). A novel hypothesis for an alkaline phosphatase 'rescue' mechanism in the hepatic acute phase immune response. Biochim Biophys Acta 1832:2044-56.
-
(2013)
Biochim Biophys Acta
, vol.1832
, pp. 2044-2056
-
-
Pike, A.F.1
Kramer, N.I.2
Blaauboer, B.J.3
-
184
-
-
0036121594
-
Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain
-
Pinsky DJ, Broekman MJ, Peschon JJ, et al. (2002). Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain. J Clin Invest 109:1031-40.
-
(2002)
J Clin Invest
, vol.109
, pp. 1031-1040
-
-
Pinsky, D.J.1
Broekman, M.J.2
Peschon, J.J.3
-
185
-
-
0028967657
-
Ecto-ATPases: Identities and functions
-
Plesner L. (1995). Ecto-ATPases: identities and functions. Int Rev Cytol 158:141-214.
-
(1995)
Int Rev Cytol
, vol.158
, pp. 141-214
-
-
Plesner, L.1
-
186
-
-
65649083808
-
Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells
-
Prosdocimo DA, Douglas DC, Romani AM, et al. (2009). Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells. Am J Physiol Cell Physiol 296: C828-39.
-
(2009)
Am J Physiol Cell Physiol
, vol.296
, pp. C828-C839
-
-
Prosdocimo, D.A.1
Douglas, D.C.2
Romani, A.M.3
-
187
-
-
0015297662
-
Metabolism of (14 C)adenine and derivatives by cerebral tissues, superfused and electrically stimulated
-
Pull I, McIlwain H. (1972). Metabolism of (14 C)adenine and derivatives by cerebral tissues, superfused and electrically stimulated. Biochem J 126:965-73.
-
(1972)
Biochem J
, vol.126
, pp. 965-973
-
-
Pull, I.1
McIlwain, H.2
-
188
-
-
34547095781
-
Prostatic acid phosphatase is not a prostate specific target
-
Quintero IB, Araujo CL, Pulkka AE, et al. (2007). Prostatic acid phosphatase is not a prostate specific target. Cancer Res 67:6549-54.
-
(2007)
Cancer Res
, vol.67
, pp. 6549-6554
-
-
Quintero, I.B.1
Araujo, C.L.2
Pulkka, A.E.3
-
189
-
-
84883780879
-
Transmembrane prostatic acid phosphatase (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma
-
Quintero IB, Herrala AM, Araujo CL, et al. (2013). Transmembrane prostatic acid phosphatase (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma. PLoS One 8:e73072.
-
(2013)
PLoS One
, vol.8
, pp. e73072
-
-
Quintero, I.B.1
Herrala, A.M.2
Araujo, C.L.3
-
190
-
-
0031754497
-
Receptors for purines and pyrimidines
-
Ralevic V, Burnstock G. (1998). Receptors for purines and pyrimidines. Pharmacol Rev 50:413-92.
-
(1998)
Pharmacol Rev
, vol.50
, pp. 413-492
-
-
Ralevic, V.1
Burnstock, G.2
-
191
-
-
33846436678
-
The E-NTPDase family of ectonucleotidases: Structure function relationship and pathophysiological significance
-
Robson SC, Sevigny J, Zimmermann H. (2006). The E-NTPDase family of ectonucleotidases: structure function relationship and pathophysiological significance. Purinergic Signal 2:409-30.
-
(2006)
Purinergic Signal
, vol.2
, pp. 409-430
-
-
Robson, S.C.1
Sevigny, J.2
Zimmermann, H.3
-
192
-
-
18044366362
-
Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation
-
Robson SC, Wu Y, Sun X, et al. (2005). Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation. Semin Thromb Hemost 31:217-33.
-
(2005)
Semin Thromb Hemost
, vol.31
, pp. 217-233
-
-
Robson, S.C.1
Wu, Y.2
Sun, X.3
-
193
-
-
0036924103
-
Cellular characterization of adenylate kinase and its isoform: Two-photon excitation fluorescence imaging and fluorescence correlation spectroscopy
-
Ruan Q, Chen Y, Gratton E, et al. (2002). Cellular characterization of adenylate kinase and its isoform: two-photon excitation fluorescence imaging and fluorescence correlation spectroscopy. Biophys J 83: 3177-87.
-
(2002)
Biophys J
, vol.83
, pp. 3177-3187
-
-
Ruan, Q.1
Chen, Y.2
Gratton, E.3
-
194
-
-
80052153431
-
Genetics in arterial calcification: Pieces of a puzzle and cogs in a wheel
-
Rutsch F, Nitschke Y, Terkeltaub R. (2011). Genetics in arterial calcification: pieces of a puzzle and cogs in a wheel. Circ Res 109: 578-92.
-
(2011)
Circ Res
, vol.109
, pp. 578-592
-
-
Rutsch, F.1
Nitschke, Y.2
Terkeltaub, R.3
-
195
-
-
0042166167
-
Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification
-
Rutsch F, Ruf N, Vaingankar S, et al. (2003). Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification. Nat Genet 34:379-81.
-
(2003)
Nat Genet
, vol.34
, pp. 379-381
-
-
Rutsch, F.1
Ruf, N.2
Vaingankar, S.3
-
196
-
-
84863836135
-
Development of a novel ectonucleotidase assay suitable for high-throughput screening
-
Sachsenmeier KF, Hay C, Brand E, et al. (2012). Development of a novel ectonucleotidase assay suitable for high-throughput screening. J Biomol Screen 17:993-8.
-
(2012)
J Biomol Screen
, vol.17
, pp. 993-998
-
-
Sachsenmeier, K.F.1
Hay, C.2
Brand, E.3
-
197
-
-
57349100406
-
Possible effects of microbial ecto-nucleoside triphosphate diphosphohydrolases on hostpathogen interactions
-
Sansom FM, Robson SC, Hartland EL. (2008). Possible effects of microbial ecto-nucleoside triphosphate diphosphohydrolases on hostpathogen interactions. Microbiol Mol Biol Rev 72:765-81.
-
(2008)
Microbiol Mol Biol Rev
, vol.72
, pp. 765-781
-
-
Sansom, F.M.1
Robson, S.C.2
Hartland, E.L.3
-
198
-
-
84856838658
-
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID
-
Sauer AV, Brigida I, Carriglio N, et al. (2012). Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID. Blood 119:1428-39.
-
(2012)
Blood
, vol.119
, pp. 1428-1439
-
-
Sauer, A.V.1
Brigida, I.2
Carriglio, N.3
-
199
-
-
0043011159
-
Extracellular ATP as a signaling molecule for epithelial cells
-
Schwiebert EM, Zsembery A. (2003). Extracellular ATP as a signaling molecule for epithelial cells. Biochim Biophys Acta 1615:7-32.
-
(2003)
Biochim Biophys Acta
, vol.1615
, pp. 7-32
-
-
Schwiebert, E.M.1
Zsembery, A.2
-
200
-
-
19944432463
-
Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I
-
Scotet E, Martinez LO, Grant E, et al. (2005). Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I. Immunity 22: 71-80.
-
(2005)
Immunity
, vol.22
, pp. 71-80
-
-
Scotet, E.1
Martinez, L.O.2
Grant, E.3
-
201
-
-
0037089425
-
Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation
-
Sevigny J, Sundberg C, Braun N, et al. (2002). Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation. Blood 99:2801-9.
-
(2002)
Blood
, vol.99
, pp. 2801-2809
-
-
Sevigny, J.1
Sundberg, C.2
Braun, N.3
-
202
-
-
0141758434
-
Rat pancreas secretes particulate ecto-nucleotidase CD39
-
Sorensen CE, Amstrup J, Rasmussen HN, et al. (2003). Rat pancreas secretes particulate ecto-nucleotidase CD39. J Physiol 551:881-92.
-
(2003)
J Physiol
, vol.551
, pp. 881-892
-
-
Sorensen, C.E.1
Amstrup, J.2
Rasmussen, H.N.3
-
203
-
-
76649109206
-
Ecto-50-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits
-
Sowa NA, Taylor-Blake B, Zylka MJ. (2010). Ecto-50-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits. J Neurosci 30:2235-44.
-
(2010)
J Neurosci
, vol.30
, pp. 2235-2244
-
-
Sowa, N.A.1
Taylor-Blake, B.2
Zylka, M.J.3
-
204
-
-
0033796779
-
Tumor-promoting functions of adenosine
-
Spychala J. (2000). Tumor-promoting functions of adenosine. Pharmacol Ther 87:161-73.
-
(2000)
Pharmacol Ther
, vol.87
, pp. 161-173
-
-
Spychala, J.1
-
206
-
-
84860382842
-
CD73-deficient mice are resistant to carcinogenesis
-
Stagg J, Beavis PA, Divisekera U, et al. (2012). CD73-deficient mice are resistant to carcinogenesis. Cancer Res 72:2190-6.
-
(2012)
Cancer Res
, vol.72
, pp. 2190-2196
-
-
Stagg, J.1
Beavis, P.A.2
Divisekera, U.3
-
207
-
-
77957564570
-
Extracellular adenosine triphosphate and adenosine in cancer
-
Stagg J, Smyth MJ. (2010). Extracellular adenosine triphosphate and adenosine in cancer. Oncogene 29:5346-58.
-
(2010)
Oncogene
, vol.29
, pp. 5346-5358
-
-
Stagg, J.1
Smyth, M.J.2
-
208
-
-
25144473903
-
NPP-type ectophosphodiesterases: Unity in diversity
-
Stefan C, Jansen S, Bollen M. (2005). NPP-type ectophosphodiesterases: unity in diversity. Trends Biochem Sci 30:542-50.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 542-550
-
-
Stefan, C.1
Jansen, S.2
Bollen, M.3
-
209
-
-
34548012770
-
Modulation of purinergic signaling by NPP-type ectophosphodiesterases
-
Stefan C, Jansen S, Bollen M. (2006). Modulation of purinergic signaling by NPP-type ectophosphodiesterases. Purinergic Signal 2: 361-70.
-
(2006)
Purinergic Signal
, vol.2
, pp. 361-370
-
-
Stefan, C.1
Jansen, S.2
Bollen, M.3
-
210
-
-
34047250594
-
Ecto-50-nucleotidase: Structure function relationships
-
Strater N. (2006). Ecto-50-nucleotidase: Structure function relationships. Purinergic Signal 2:343-50.
-
(2006)
Purinergic Signal
, vol.2
, pp. 343-350
-
-
Strater, N.1
-
211
-
-
84880492710
-
Tissue-nonspecific alkaline phosphatase acts redundantly with pap and nt5e to generate adenosine in the dorsal spinal cord
-
Street SE, Kramer NJ, Walsh PL, et al. (2013). Tissue-nonspecific alkaline phosphatase acts redundantly with pap and nt5e to generate adenosine in the dorsal spinal cord. J Neurosci 33:11314-22.
-
(2013)
J Neurosci
, vol.33
, pp. 11314-11322
-
-
Street, S.E.1
Kramer, N.J.2
Walsh, P.L.3
-
213
-
-
0025214366
-
The clinical biochemistry of 50-nucleotidase
-
Sunderman Jr FW,. (1990). The clinical biochemistry of 50-nucleotidase. Ann Clin Lab Sci 20:123-39.
-
(1990)
Ann Clin Lab Sci
, vol.20
, pp. 123-139
-
-
Sunderman, F.W.1
-
214
-
-
44449146084
-
CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes
-
Takedachi M, Qu D, Ebisuno Y, et al. (2008). CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes. J Immunol 180:6288-96.
-
(2008)
J Immunol
, vol.180
, pp. 6288-6296
-
-
Takedachi, M.1
Qu, D.2
Ebisuno, Y.3
-
215
-
-
0034813884
-
Inorganic pyrophosphate generation and disposition in pathophysiology
-
Terkeltaub RA. (2001). Inorganic pyrophosphate generation and disposition in pathophysiology. Am J Physiol Cell Physiol 281:C1-11.
-
(2001)
Am J Physiol Cell Physiol
, vol.281
, pp. C1-11
-
-
Terkeltaub, R.A.1
-
216
-
-
0030908844
-
Neuronal release of soluble nucleotidases and their role in neurotransmitter inactivation
-
Todorov LD, Mihaylova-Todorova S, Westfall TD, et al. (1997). Neuronal release of soluble nucleotidases and their role in neurotransmitter inactivation. Nature 387:76-9.
-
(1997)
Nature
, vol.387
, pp. 76-79
-
-
Todorov, L.D.1
Mihaylova-Todorova, S.2
Westfall, T.D.3
-
217
-
-
33748614075
-
Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro
-
Toro A, Paiva M, Ackerley C, et al. (2006). Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro. Cell Immunol 240:107-15.
-
(2006)
Cell Immunol
, vol.240
, pp. 107-115
-
-
Toro, A.1
Paiva, M.2
Ackerley, C.3
-
218
-
-
34247534260
-
Regulation and biological activities of the autotaxin-LPA axis
-
van Meeteren LA, Moolenaar WH. (2007). Regulation and biological activities of the autotaxin-LPA axis. Prog Lipid Res 46:145-60.
-
(2007)
Prog Lipid Res
, vol.46
, pp. 145-160
-
-
Van Meeteren, L.A.1
Moolenaar, W.H.2
-
219
-
-
33745466418
-
Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development
-
van Meeteren LA, Ruurs P, Stortelers C, et al. (2006). Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol 26:5015-22.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5015-5022
-
-
Van Meeteren, L.A.1
Ruurs, P.2
Stortelers, C.3
-
220
-
-
84883351219
-
Role of the ectonucleotidase NTPDase2 in taste bud function
-
Vandenbeuch A, Anderson CB, Parnes J, et al. (2013). Role of the ectonucleotidase NTPDase2 in taste bud function. Proc Natl Acad Sci USA 110:14789-94.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 14789-14794
-
-
Vandenbeuch, A.1
Anderson, C.B.2
Parnes, J.3
-
221
-
-
0042121327
-
Determination of phosphate in nanomolar range by an enzyme-coupling fluorescent method
-
Vazquez MJ, Rodriguez B, Zapatero C, et al. (2003). Determination of phosphate in nanomolar range by an enzyme-coupling fluorescent method. Anal Biochem 320:292-8.
-
(2003)
Anal Biochem
, vol.320
, pp. 292-298
-
-
Vazquez, M.J.1
Rodriguez, B.2
Zapatero, C.3
-
222
-
-
79959880532
-
Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle
-
Villa-Bellosta R, Wang X, Millan JL, et al. (2011). Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle. Am J Physiol Heart Circ Physiol 301:H61-8.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
, pp. H61-H68
-
-
Villa-Bellosta, R.1
Wang, X.2
Millan, J.L.3
-
223
-
-
84912116799
-
Adenosine inhibits tumor cell invasion via receptor-independent mechanisms
-
Virtanen SS, Kukkonen-Macchi A, Vainio M, et al. (2014). Adenosine inhibits tumor cell invasion via receptor-independent mechanisms. Mol Cancer Res. doi: 10.1158/1541-7786.MCR-14-0302-T [in press].
-
(2014)
Mol Cancer Res
-
-
Virtanen, S.S.1
Kukkonen-Macchi, A.2
Vainio, M.3
-
224
-
-
84863844851
-
Increased CD39 nucleotidase activity on microparticles from patients with idiopathic pulmonary arterial hypertension
-
Visovatti SH, Hyman MC, Bouis D, et al. (2012). Increased CD39 nucleotidase activity on microparticles from patients with idiopathic pulmonary arterial hypertension. PLoS One 7:e40829.
-
(2012)
PLoS One
, vol.7
, pp. e40829
-
-
Visovatti, S.H.1
Hyman, M.C.2
Bouis, D.3
-
225
-
-
0038713657
-
Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases
-
Vollmayer P, Clair T, Goding JW, et al. (2003). Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases. Eur J Biochem 270:2971-8.
-
(2003)
Eur J Biochem
, vol.270
, pp. 2971-2978
-
-
Vollmayer, P.1
Clair, T.2
Goding, J.W.3
-
226
-
-
70449159416
-
Histochemistry of hepatic phosphatases of a physiologic pH; With special reference to the demonstration of bile canaliculi
-
Wachstein M, Meisel E. (1957). Histochemistry of hepatic phosphatases of a physiologic pH; with special reference to the demonstration of bile canaliculi. Am J Clin Pathol 27:13-23.
-
(1957)
Am J Clin Pathol
, vol.27
, pp. 13-23
-
-
Wachstein, M.1
Meisel, E.2
-
227
-
-
84881607839
-
Neuronal transporter and astrocytic ATP exocytosis underlie activity-dependent adenosine release in the hippocampus
-
Wall MJ, Dale N. (2013). Neuronal transporter and astrocytic ATP exocytosis underlie activity-dependent adenosine release in the hippocampus. J Physiol 591:3853-71.
-
(2013)
J Physiol
, vol.591
, pp. 3853-3871
-
-
Wall, M.J.1
Dale, N.2
-
228
-
-
84858640637
-
Adenosine signaling: Good or bad in erectile function?
-
Wen J, Xia Y. (2012). Adenosine signaling: good or bad in erectile function? Arterioscler Thromb Vasc Biol 32:845-50.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 845-850
-
-
Wen, J.1
Xia, Y.2
-
229
-
-
17644435744
-
Nucleoside monophosphate kinases: Structure, mechanism, and substrate specificity
-
Yan H, Tsai M-D. (1999). Nucleoside monophosphate kinases: structure, mechanism, and substrate specificity. Adv Enzymol Relat Areas Mol Biol 73:103-34.
-
(1999)
Adv Enzymol Relat Areas Mol Biol
, vol.73
, pp. 103-134
-
-
Yan, H.1
Tsai, M.-D.2
-
230
-
-
0034050561
-
Effect of shear stress on the release of soluble ecto-enzymes ATPase and 50-nucleotidase along with endogenous ATP from vascular endothelial cells
-
Yegutkin G, Bodin P, Burnstock G. (2000). Effect of shear stress on the release of soluble ecto-enzymes ATPase and 50-nucleotidase along with endogenous ATP from vascular endothelial cells. Br J Pharmacol 129:921-6.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 921-926
-
-
Yegutkin, G.1
Bodin, P.2
Burnstock, G.3
-
231
-
-
41949083203
-
Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade
-
Yegutkin GG. (2008). Nucleotide- and nucleoside-converting ectoenzymes: important modulators of purinergic signalling cascade. Biochim Biophys Acta 1783:673-94.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 673-694
-
-
Yegutkin, G.G.1
-
232
-
-
84855203925
-
Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells
-
Yegutkin GG, Helenius M, Kaczmarek E, et al. (2011a). Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells. Angiogenesis 14:503-13.
-
(2011)
Angiogenesis
, vol.14
, pp. 503-513
-
-
Yegutkin, G.G.1
Helenius, M.2
Kaczmarek, E.3
-
233
-
-
0035148585
-
Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions
-
Yegutkin GG, Henttinen T, Jalkanen S. (2001). Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions. FASEB J 15:251-60.
-
(2001)
FASEB J
, vol.15
, pp. 251-260
-
-
Yegutkin, G.G.1
Henttinen, T.2
Jalkanen, S.3
-
234
-
-
0036798380
-
The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells
-
Yegutkin GG, Henttinen T, Samburski SS, et al. (2002). The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells. Biochem J 367:121-8.
-
(2002)
Biochem J
, vol.367
, pp. 121-128
-
-
Yegutkin, G.G.1
Henttinen, T.2
Samburski, S.S.3
-
235
-
-
77954496088
-
Disordered lymphoid purine metabolism contributes to the pathogenesis of persistent Borrelia garinii infection in mice
-
Yegutkin GG, Hytonen J, Samburski SS, et al. (2010). Disordered lymphoid purine metabolism contributes to the pathogenesis of persistent Borrelia garinii infection in mice. J Immunol 184:5112-20.
-
(2010)
J Immunol
, vol.184
, pp. 5112-5120
-
-
Yegutkin, G.G.1
Hytonen, J.2
Samburski, S.S.3
-
236
-
-
79955153842
-
Altered purinergic signaling in CD73-deficient mice inhibits tumor progression
-
Yegutkin GG, Marttila-Ichihara F, Karikoski M, et al. (2011b). Altered purinergic signaling in CD73-deficient mice inhibits tumor progression. Eur J Immunol 41:1231-41.
-
(2011)
Eur J Immunol
, vol.41
, pp. 1231-1241
-
-
Yegutkin, G.G.1
Marttila-Ichihara, F.2
Karikoski, M.3
-
237
-
-
33746616390
-
The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor
-
Yegutkin GG, Mikhailov A, Samburski SS, et al. (2006a). The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor. Mol Biol Cell 17:3378-85.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 3378-3385
-
-
Yegutkin, G.G.1
Mikhailov, A.2
Samburski, S.S.3
-
238
-
-
0037590102
-
Soluble purineconverting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions
-
Yegutkin GG, Samburski SS, Jalkanen S. (2003). Soluble purineconverting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions. FASEB J 17:1328-30.
-
(2003)
FASEB J
, vol.17
, pp. 1328-1330
-
-
Yegutkin, G.G.1
Samburski, S.S.2
Jalkanen, S.3
-
239
-
-
33749578267
-
ATP-consuming and ATP-generating enzymes secreted by pancreas
-
Yegutkin GG, Samburski SS, Jalkanen S, et al. (2006b). ATP-consuming and ATP-generating enzymes secreted by pancreas. J Biol Chem 281: 29441-7.
-
(2006)
J Biol Chem
, vol.281
, pp. 29441-29447
-
-
Yegutkin, G.G.1
Samburski, S.S.2
Jalkanen, S.3
-
240
-
-
33847689290
-
Intravascular ADP and soluble nucleotidases contribute to acute prothrombotic state during vigorous exercise in humans
-
Yegutkin GG, Samburski SS, Mortensen SP, et al. (2007). Intravascular ADP and soluble nucleotidases contribute to acute prothrombotic state during vigorous exercise in humans. J Physiol 579:553-64.
-
(2007)
J Physiol
, vol.579
, pp. 553-564
-
-
Yegutkin, G.G.1
Samburski, S.S.2
Mortensen, S.P.3
-
241
-
-
84865747829
-
Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities
-
Yegutkin GG, Wieringa B, Robson SC, et al. (2012). Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities. FASEB J 26:3875-83.
-
(2012)
FASEB J
, vol.26
, pp. 3875-3883
-
-
Yegutkin, G.G.1
Wieringa, B.2
Robson, S.C.3
-
242
-
-
0027209037
-
Alteration of 50-nucleotidase properties in rat adipose and liver plasma membranes after 1 Gy whole-body gamma-irradiation
-
Yegutkin GG, Yakubovskii SM, Gatsko GG. (1993). Alteration of 50-nucleotidase properties in rat adipose and liver plasma membranes after 1 Gy whole-body gamma-irradiation. Int J Radiat Biol 63: 583-7.
-
(1993)
Int J Radiat Biol
, vol.63
, pp. 583-587
-
-
Yegutkin, G.G.1
Yakubovskii, S.M.2
Gatsko, G.G.3
-
243
-
-
85027938179
-
A role for nucleotides in support of breast cancer angiogenesis: Heterologous receptor signalling
-
Yokdang N, Tellez JD, Tian H, et al. (2011). A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling. Br J Cancer 104:1628-40.
-
(2011)
Br J Cancer
, vol.104
, pp. 1628-1640
-
-
Yokdang, N.1
Tellez, J.D.2
Tian, H.3
-
245
-
-
84905455228
-
Targeting cancer-derived adenosine: New therapeutic approaches
-
Young A, Mittal D, Stagg J, et al. (2014). Targeting cancer-derived adenosine: new therapeutic approaches. Cancer Discov 4:879-88.
-
(2014)
Cancer Discov
, vol.4
, pp. 879-888
-
-
Young, A.1
Mittal, D.2
Stagg, J.3
-
246
-
-
26844457398
-
Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity
-
Zavialov AV, Engstrom A. (2005). Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity. Biochem J 391:51-7.
-
(2005)
Biochem J
, vol.391
, pp. 51-57
-
-
Zavialov, A.V.1
Engstrom, A.2
-
247
-
-
77956417545
-
Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages
-
Zavialov AV, Gracia E, Glaichenhaus N, et al. (2010a). Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages. J Leukoc Biol 88:279-90.
-
(2010)
J Leukoc Biol
, vol.88
, pp. 279-290
-
-
Zavialov, A.V.1
Gracia, E.2
Glaichenhaus, N.3
-
248
-
-
77951247730
-
Structural basis for the growth factor activity of human adenosine deaminase ADA2
-
Zavialov AV, Yu X, Spillmann D, et al. (2010b). Structural basis for the growth factor activity of human adenosine deaminase ADA2. J Biol Chem 285:12367-77.
-
(2010)
J Biol Chem
, vol.285
, pp. 12367-12377
-
-
Zavialov, A.V.1
Yu, X.2
Spillmann, D.3
-
249
-
-
84894503251
-
Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB- 071
-
Zebisch M, Baqi Y, Schafer P, et al. (2014). Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB- 071. J Struct Biol 185:336-41.
-
(2014)
J Struct Biol
, vol.185
, pp. 336-341
-
-
Zebisch, M.1
Baqi, Y.2
Schafer, P.3
-
250
-
-
84855762914
-
Crystallographic evidence for a domain motion in rat nucleoside triphosphate diphosphohydrolase (NTPDase) 1
-
Zebisch M, Krauss M, Schafer P, et al. (2012). Crystallographic evidence for a domain motion in rat nucleoside triphosphate diphosphohydrolase (NTPDase) 1. J Mol Biol 415:288-306.
-
(2012)
J Mol Biol
, vol.415
, pp. 288-306
-
-
Zebisch, M.1
Krauss, M.2
Schafer, P.3
-
251
-
-
33646456788
-
CD73/ecto-50- nucleotidase protects against vascular inflammation and neointima formation
-
Zernecke A, Bidzhekov K, Ozuyaman B, et al. (2006). CD73/ecto-50- nucleotidase protects against vascular inflammation and neointima formation. Circulation 113:2120-7.
-
(2006)
Circulation
, vol.113
, pp. 2120-2127
-
-
Zernecke, A.1
Bidzhekov, K.2
Ozuyaman, B.3
-
252
-
-
84895461649
-
Early-onset stroke and vasculopathy associated with mutations in ADA2
-
Zhou Q, Yang D, Ombrello AK, et al. (2014). Early-onset stroke and vasculopathy associated with mutations in ADA2. N Engl J Med 370: 911-20.
-
(2014)
N Engl J Med
, vol.370
, pp. 911-920
-
-
Zhou, Q.1
Yang, D.2
Ombrello, A.K.3
-
253
-
-
77949518257
-
Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
-
Zhou Y, Murthy JN, Zeng D, et al. (2010). Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. PLoS One 5: e9224.
-
(2010)
PLoS One
, vol.5
, pp. e9224
-
-
Zhou, Y.1
Murthy, J.N.2
Zeng, D.3
-
254
-
-
79954612475
-
Fluorescent and colorimetric chemosensors for detection of nucleotides, FAD and NADH: Highlighted research during 2004-2010
-
Zhou Y, Xu Z, Yoon J. (2011). Fluorescent and colorimetric chemosensors for detection of nucleotides, FAD and NADH: highlighted research during 2004-2010. Chem Soc Rev 40:2222-35.
-
(2011)
Chem Soc Rev
, vol.40
, pp. 2222-2235
-
-
Zhou, Y.1
Xu, Z.2
Yoon, J.3
-
255
-
-
0026729643
-
50-Nucleotidase: Molecular structure and functional aspects
-
Zimmermann H. (1992). 50-Nucleotidase: molecular structure and functional aspects. Biochem J 285:345-65.
-
(1992)
Biochem J
, vol.285
, pp. 345-365
-
-
Zimmermann, H.1
-
256
-
-
0030221465
-
Biochemistry, localization and functional roles of ecto-nucleotidases in the nervous system
-
Zimmermann H. (1996). Biochemistry, localization and functional roles of ecto-nucleotidases in the nervous system. Prog Neurobiol 49: 589-618.
-
(1996)
Prog Neurobiol
, vol.49
, pp. 589-618
-
-
Zimmermann, H.1
-
257
-
-
68349124954
-
Prostatic acid phosphatase, a neglected ectonucleotidase
-
Zimmermann H. (2009). Prostatic acid phosphatase, a neglected ectonucleotidase. Purinergic Signal 5:273-5.
-
(2009)
Purinergic Signal
, vol.5
, pp. 273-275
-
-
Zimmermann, H.1
-
258
-
-
84861529229
-
Cellular function and molecular structure of ecto-nucleotidases
-
Zimmermann H, Zebisch M, Strater N. (2012). Cellular function and molecular structure of ecto-nucleotidases. Purinergic Signal 8: 437-502.
-
(2012)
Purinergic Signal
, vol.8
, pp. 437-502
-
-
Zimmermann, H.1
Zebisch, M.2
Strater, N.3
-
259
-
-
79954578322
-
Pain-relieving prospects for adenosine receptors and ectonucleotidases
-
Zylka MJ. (2011). Pain-relieving prospects for adenosine receptors and ectonucleotidases. Trends Mol Med 17:188-96.
-
(2011)
Trends Mol Med
, vol.17
, pp. 188-196
-
-
Zylka, M.J.1
-
260
-
-
53049093740
-
Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine
-
Zylka MJ, Sowa NA, Taylor-Blake B, et al. (2008). Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine. Neuron 60:111-22.
-
(2008)
Neuron
, vol.60
, pp. 111-122
-
-
Zylka, M.J.1
Sowa, N.A.2
Taylor-Blake, B.3
|