Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency

Journal of Biological Chemistry

Volumn 273, Issue 9, 1998, Pages 5093-5100

  Blackburn, Michael R ^b   Datta, Surjit K ^b   Kellems, Rodney E ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; ADENOSYLHOMOCYSTEINASE; DEOXYADENOSINE; DEOXYADENOSINE TRIPHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DISEASE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; ENZYME INHIBITION; FETUS; GENETIC ENGINEERING; KIDNEY DISEASE; LUNG INSUFFICIENCY; LYMPHOCYTOPENIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; THYMUS;

ADENOSINE; ADENOSINE DEAMINASE; ADENOSYLHOMOCYSTEINASE; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; B-LYMPHOCYTES; BONE AND BONES; DEOXYADENOSINES; GENETIC ENGINEERING; HYDROLASES; KIDNEY; LUNG; LYMPHOCYTE COUNT; LYMPHOPENIA; MICE; PULMONARY VALVE INSUFFICIENCY; PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS; RESEARCH DESIGN; SEVERE COMBINED IMMUNODEFICIENCY; SPLEEN; T-LYMPHOCYTES; THYMUS GLAND; TISSUE DISTRIBUTION;

EID: 0032570814     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.9.5093     Document Type: Article

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