Crystal structure of the human ecto-5′-nucleotidase (CD73): Insights into the regulation of purinergic signaling

Structure

Volumn 20, Issue 12, 2012, Pages 2161-2173

  Knapp, Karen ^a,b   Zebisch, Matthias ^a,c   Pippel, Jan ^a   El Tayeb, Ali ^d   Müller, Christa E ^d   Sträter, Norbert ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ECTO 5' NUCLEOTIDASE; FLAVONOID; PURINERGIC RECEPTOR;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME CONFORMATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

5'-NUCLEOTIDASE; ADENOSINE; ADENOSINE DIPHOSPHATE; AMINO ACID SEQUENCE; CATALYTIC DOMAIN; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FLAVONOIDS; GPI-LINKED PROTEINS; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; SIGNAL TRANSDUCTION; STRUCTURAL HOMOLOGY, PROTEIN; ZINC;

VERTEBRATA;

EID: 84870480855     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.10.001     Document Type: Article

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