The many isoforms of human adenylate kinases

International Journal of Biochemistry and Cell Biology

Volumn 49, Issue 1, 2014, Pages 75-83

  Panayiotou, Christakis ^a   Solaroli, Nicola ^a   Karlsson, Anna ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adenine nucleotides; Adenylate kinases; Nucleoside analogues; Nucleoside diphosphate kinases; Nucleoside monophosphate kinases

Indexed keywords

ADENYLATE KINASE; ADENYLATE KINASE 1; ADENYLATE KINASE 2; ADENYLATE KINASE 3; ADENYLATE KINASE 4; ADENYLATE KINASE 5; ADENYLATE KINASE 6; ADENYLATE KINASE 7; ADENYLATE KINASE 8; ADENYLATE KINASE 9; DEOXYADENOSINE; DEOXYCYTIDINE; NUCLEOSIDE ANALOG; NUCLEOSIDE DIPHOSPHATE KINASE; NUCLEOSIDE MONOPHOSPHATE KINASE; PURINE NUCLEOTIDE; UNCLASSIFIED DRUG; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ISOENZYME;

ARTICLE; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE METABOLISM; PHOSPHORYLATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; AMINO ACID SEQUENCE; CLASSIFICATION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYLOGENY; SEQUENCE HOMOLOGY;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; AMINO ACID SEQUENCE; HUMANS; ISOENZYMES; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 84894239646     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.01.014     Document Type: Review

References (67)

1. M. Amiri, F. Conserva, C. Panayiotou, A. Karlsson, and N. Solaroli The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase Int J Biochem Cell Biol 45 2013 925 931
2. T. Arima, H. Akiyoshi, and S. Fujii Characterization of pyrimidine nucleoside monophosphokinase in normal and malignant tissues Cancer Res 37 1977 1593 1597
3. E.S. Arner On the phosphorylation of 2-Chlorodeoxyadenosine (CdA) and its correlation with clinical response in leukemia treatment Leuk Lymphoma 21 1996 225 231
4. E.S. Arner, and S. Eriksson Mammalian deoxyribonucleoside kinases Pharmacol Ther 67 1995 155 186
5. J.L. Badano, N. Mitsuma, P.L. Beales, and N. Katsanis The ciliopathies: an emerging class of human genetic disorders Annu Rev Genomics Hum Genet 7 2006 125 148
6. P. Barraud, L. Amrein, E. Dobremez, S. Dabernat, K. Masse, and M. Larou et al. Differential expression of nm23 genes in adult mouse dorsal root ganglia J Comp Neurol 444 2002 306 323
7. J.M. Berg, J.L. Tymoczko, and L. Stryer Biochemistry 5th ed. 2002 WH Freeman and Company ISBN-10: 0-7167-3051-02002
8. P. Bianchi, M. Zappa, E. Bredi, C. Vercellati, G. Pelissero, and F. Barraco et al. A case of complete adenylate kinase deficiency due to a nonsense mutation in AK-1 gene (Arg 107 → Stop, CGA → TGA) associated with chronic haemolytic anaemia Br J Haematol 105 1999 75 79
9. M. Boissan, S. Dabernat, E. Peuchant, U. Schlattner, I. Lascu, and M.L. Lacombe The mammalian Nm23/NDPK family: from metastasis control to cilia movement Mol Cell Biochem 329 2009 51 62
10. W.A. Brady, M.S. Kokoris, M. Fitzgibbon, and M.E. Black Cloning, characterization, and modeling of mouse and human guanylate kinases J Biol Chem 271 1996 16734 16740
11. M. Cattaneo, and C. Gachet ADP receptors and clinical bleeding disorders Arterioscler Thromb Vasc Biol 19 1999 2281 2285
12. D.P. Dimmock, J.K. Dunn, A. Feigenbaum, A. Rupar, R. Horvath, and P. Freisinger et al. Abnormal neurological features predict poor survival and should preclude liver transplantation in patients with deoxyguanosine kinase deficiency Liver Transpl 14 2008 1480 1485
13. P. Dzeja, and A. Terzic Adenylate kinase and amp signaling networks: metabolic monitoring, signal communication and body energy sensing Int J Mol Sci 10 2009 1729 1772
14. A. Fernandez-Gonzalez, S. Kourembanas, T.A. Wyatt, and S.A. Mitsialis Mutation of murine adenylate kinase 7 underlies a primary ciliary dyskinesia phenotype Am J Respir Cell Mol Biol 40 2009 305 313
15. J. Fitzgibbon, N. Katsanis, D. Wells, J. Delhanty, W. Vallins, and D.M. Hunt Human guanylate kinase (GUK1): cDNA sequence, expression and chromosomal localisation FEBS Lett 385 1996 185 188
16. K. Fukami-Kobayashi, M. Nosaka, A. Nakazawa, and M. Go Ancient divergence of long and short isoforms of adenylate kinase: molecular evolution of the nucleoside monophosphate kinase family FEBS Lett 385 1996 214 220
17. C.M. Galmarini, J.R. Mackey, and C. Dumontet Nucleoside analogues: mechanisms of drug resistance and reversal strategies Leukemia 15 2001 875 890
18. C.M. Galmarini, J.R. Mackey, and C. Dumontet Nucleoside analogues and nucleobases in cancer treatment Lancet Oncol 3 2002 415 424
19. C.R. Hancock, E. Janssen, and R.L. Terjung Contraction-mediated phosphorylation of AMPK is lower in skeletal muscle of adenylate kinase-deficient mice J Appl Physiol 100 2006 406 413
20. P. Huang, S. Chubb, and W. Plunkett Termination of DNA synthesis by 9-beta-d-arabinofuranosyl-2-Fluoroadenine. A mechanism for cytotoxicity J Biol Chem 265 1990 16617 16625
21. S.H. Huang, A. Tang, B. Drisco, S.Q. Zhang, R. Seeger, and C. Li et al. Human dTMP kinase: gene expression and enzymatic activity coinciding with cell cycle progression and cell growth DNA Cell Biol 13 1994 461 471
22. T. Jamil, R.A. Fisher, and H. Harris Studies on the properties and tissue distribution of the isozymes of guanylate kinase in man Hum Hered 25 1975 402 413
23. J.C. Khoo, and P.J. Russell Isoenzymes of adenylate kinase in human tissue Biochim Biophys Acta 268 1972 98 101
24. C. Lagresle-Peyrou, E.M. Six, C. Picard, F. Rieux-Laucat, V. Michel, and A. Ditadi et al. Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness Nat Genet 41 2009 106 111
25. H.J. Lee, J.O. Pyo, Y. Oh, H.J. Kim, S.H. Hong, and Y.J. Jeon et al. AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10 Nat Cell Biol 9 2007 1303 1310
26. L.S. Lee, and Y. Cheng Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemia J Biol Chem 252 1977 5686 5691
27. T.P. Leist, and R. Weissert Cladribine: mode of action and implications for treatment of multiple sclerosis Clin Neuropharmacol 34 2011 28 35
28. W. Lewis, and M.C. Dalakas Mitochondrial toxicity of antiviral drugs Nat Med 1 1995 417 422
29. S. Lindemalm, J. Liliemark, G. Juliusson, R. Larsson, and F. Albertioni Cytotoxicity and pharmacokinetics of cladribine metabolite, 2-Chloroadenine in patients with leukemia Cancer Lett 210 2004 171 177
30. R. Liu, A.L. Strom, J. Zhai, J. Gal, S. Bao, and W. Gong et al. Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase Int J Biochem Cell Biol 41 2009 1371 1380
31. H. Lodish, A. Berk, S.L. Zipursky, P. Matsudaira, D. Baltimore, and J. Darnell Molecular Cell Biology 4th ed. 2000 WH Freeman and Company ISBN-10: 0-7167-3136-32000
32. K.M. Lonergan, R. Chari, R.J. Deleeuw, A. Shadeo, B. Chi, and M.S. Tsao et al. Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression Am J Respir Cell Mol Biol 35 2006 651 661
33. J. Lukenbill, and M. Kalaycio Fludarabine: a review of the clear benefits and potential harms Leuk Res 37 2013 986 994
34. S. Matsuura, M. Igarashi, Y. Tanizawa, M. Yamada, F. Kishi, and T. Kajii et al. Human adenylate kinase deficiency associated with hemolytic anemia. A single base substitution affecting solubility and catalytic activity of the cytosolic adenylate kinase J Biol Chem 264 1989 10148 10155
35. S. Noble, and K.L. Goa Gemcitabine. A review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer Drugs 54 1997 447 472
36. T. Noma, K. Fujisawa, Y. Yamashiro, M. Shinohara, A. Nakazawa, and T. Gondo et al. Structure and expression of human mitochondrial adenylate kinase targeted to the mitochondrial matrix Biochem J 358 2001 225 232
37. T. Noma, S. Song, Y.S. Yoon, S. Tanaka, and A. Nakazawa cDNA cloning and tissue-specific expression of the gene encoding human adenylate kinase isozyme 2 Biochim Biophys Acta 1395 1998 34 39
38. C. Panayiotou, N. Solaroli, M. Johansson, and A. Karlsson Evidence of an intact N-terminal translocation sequence of human mitochondrial adenylate kinase 4 Int J Biochem Cell Biol 42 2010 62 69
39. C. Panayiotou, N. Solaroli, Y. Xu, M. Johansson, and A. Karlsson The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes Biochem J 433 2011 527 534
40. U. Pannicke, M. Honig, I. Hess, C. Friesen, K. Holzmann, and E.M. Rump et al. Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2 Nat Genet 41 2009 101 105
41. W.B. Parker, A.R. Bapat, J.X. Shen, A.J. Townsend, and Y.C. Cheng Interaction of 2-halogenated dATP analogs (F, Cl, and Br) with human DNA polymerases, DNA primase, and ribonucleotide reductase Mol Pharmacol 34 1988 485 491
42. D. Pucar, P. Bast, R.J. Gumina, L. Lim, C. Drahl, and N. Juranic et al. Adenylate kinase AK1 knockout heart: energetics and functional performance under ischemia-reperfusion Am J Physiol Heart Circ Physiol 283 2002 H776 H782
43. D. Pucar, E. Janssen, P.P. Dzeja, N. Juranic, S. Macura, and B. Wieringa et al. Compromised energetics in the adenylate kinase AK1 gene knockout heart under metabolic stress J Biol Chem 275 2000 41424 41429
44. A. Qualtieri, V. Pedace, M.G. Bisconte, M. Bria, B. Gulino, and V. Andreoli et al. Severe erythrocyte adenylate kinase deficiency due to homozygous A → G substitution at codon 164 of human AK1 gene associated with chronic haemolytic anaemia Br J Haematol 99 1997 770 776
45. G.H. Reem De novo purine biosynthesis by two pathways in Burkitt lymphoma cells and in human spleen J Clin Invest 51 1972 1058 1062
46. N.D. Reese, and G.J. Schiller High-dose cytarabine (HD araC) in the treatment of leukemias: a review Curr Hematol Malig Rep 8 2013 141 148
47. P. Reichard Interactions between deoxyribonucleotide and DNA synthesis Annu Rev Biochem 57 1988 349 374
48. H. Ren, L. Wang, M. Bennett, Y. Liang, X. Zheng, and F. Lu et al. The crystal structure of human adenylate kinase 6: an adenylate kinase localized to the cell nucleus Proc Natl Acad Sci U S A 102 2005 303 308
49. 2+ at 2.2 A: implications for water-mediated specificity Biochemistry 35 1996 9716 9727
50. K.J. Simpson, L.M. Selfors, J. Bui, A. Reynolds, D. Leake, and A. Khvorova et al. Identification of genes that regulate epithelial cell migration using an siRNA screening approach Nat Cell Biol 10 2008 1027 1038
51. C. Snow, G. Qi, and S. Hayward Essential dynamics sampling study of adenylate kinase: comparison to citrate synthase and implication for the hinge and shear mechanisms of domain motions Proteins 67 2007 325 337
52. N. Solaroli, C. Panayiotou, M. Johansson, and A. Karlsson Identification of two active functional domains of human adenylate kinase 5 FEBS Lett 583 2009 2872 2876
53. J.Y. Su, and R.A. Sclafani Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast Nucleic Acids Res 19 1991 823 827
54. W.C. Tseng, D. Derse, Y.C. Cheng, R.W. Brockman, and L.L. Bennett Jr. In vitro biological activity of 9-beta-d-arabinofuranosyl-2-Fluoroadenine and the biochemical actions of its triphosphate on DNA polymerases and ribonucleotide reductase from HeLa cells Mol Pharmacol 21 1982 474 477
55. E. Tuzun, J.E. Rossi, S.F. Karner, A.F. Centurion, and J. Dalmau Adenylate kinase 5 autoimmunity in treatment refractory limbic encephalitis J Neuroimmunol 186 2007 177 180
56. A.R. Van Rompay, M. Johansson, and A. Karlsson Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein Eur J Biochem 261 1999 509 517
57. A.R. Van Rompay, M. Johansson, and A. Karlsson Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme Mol Pharmacol 56 1999 562 569
58. A.R. Van Rompay, M. Johansson, and A. Karlsson Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases Pharmacol Ther 87 2000 189 198
59. L. Wang The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates FEBS J 274 2007 1983 1990
60. W.S. Wang, C.H. Tzeng, T.J. Chiou, J.H. Liu, R.K. Hsieh, and C.C. Yen et al. High-dose cytarabine and mitoxantrone as salvage therapy for refractory non-Hodgkin's lymphoma Jpn J Clin Oncol 27 1997 154 157
61. P.C. Whitford, S. Gosavi, and J.N. Onuchic Conformational transitions in adenylate kinase. Allosteric communication reduces misligation J Biol Chem 283 2008 2042 2048
62. D.E. Wilson, S. Povey, and H. Harris Adenylate kinases in man: evidence for a third locus Ann Hum Genet 39 1976 305 313
63. G. Xu, P. O'Connell, J. Stevens, and R. White Characterization of human adenylate kinase 3 (AK3) cDNA and mapping of the AK3 pseudogene to an intron of the NF1 gene Genomics 13 1992 537 542
64. Y. Xu, M. Johansson, and A. Karlsson Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria J Biol Chem 283 2008 1563 1571
65. T. Yoneda, M. Sato, M. Maeda, and H. Takagi Identification of a novel adenylate kinase system in the brain: cloning of the fourth adenylate kinase Brain Res Mol Brain Res 62 1998 187 195
66. M.A. Zariwala, M.R. Knowles, and H. Omran Genetic defects in ciliary structure and function Annu Rev Physiol 69 2007 423 450
67. S.J. Zhang, M.E. Sandstrom, J. Aydin, H. Westerblad, B. Wieringa, and A. Katz Activation of glucose transport and AMP-activated protein kinase during muscle contraction in adenylate kinase-1 knockout mice Acta Physiol (Oxf) 192 2008 413 420