Mechanisms of disease: Ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors

Nature Clinical Practice Endocrinology and Metabolism

Volumn 2, Issue 12, 2006, Pages 694-701

  Abate, Nicola ^a   Chandalia, Manisha ^a   Di Paola, Rosa ^c   Foster, Daniel W ^b   Grundy, Scott M ^b   Trischitta, Vincenzo ^c,d,e  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e Scientific Institute   (Italy)

Author keywords

E NPP1; Genetics; Insulin receptor; Insulin resistance; PC 1

Indexed keywords

BIOLOGICAL MARKER; ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MEMBRANE PROTEIN; NUCLEOTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHODIESTERASE; PLASMA CELL MEMBRANE GLYCOPROTEIN PC 1; PROTEIN KINASE B BETA; PROTEIN TYROSINE PHOSPHATASE 1B; TUMOR NECROSIS FACTOR;

AUTOPHOSPHORYLATION; CARDIOVASCULAR DISEASE; DIABETES MELLITUS; ENZYME PHOSPHORYLATION; GENE MUTATION; GENETIC MODEL; GENOTYPE PHENOTYPE CORRELATION; HAPLOTYPE; HUMAN; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; HUMANS; INSULIN RESISTANCE; MODELS, BIOLOGICAL; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; RECEPTOR, INSULIN;

EID: 33845397703     PISSN: 17458366     EISSN: 17458374     Source Type: Journal    
DOI: 10.1038/ncpendmet0367     Document Type: Review

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