NPP-type ectophosphodiesterases: Unity in diversity

Trends in Biochemical Sciences

Volumn 30, Issue 10, 2005, Pages 542-550

  Stefan, Cristiana ^a   Jansen, Silvia ^a   Bollen, Mathieu ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDE PYROPHOSPHATASE; PHOSPHODIESTERASE;

ANGIOGENESIS; BONE MINERALIZATION; CATALYSIS; CELL MOTILITY; CELL PROLIFERATION; CHEMICAL BOND; HUMAN; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 25144473903     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2005.08.005     Document Type: Review

References (75)

1. M. Umezu-Goto Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production J. Cell Biol. 158 2002 227 233
2. H. Sakagami Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/pyrophosphodiesterase (NPP) family J. Biol. Chem. 280 2005 23084 23093
3. R. Duan Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family J. Biol. Chem. 278 2003 38528 38536
4. M. Bollen Nucleotide pyrophosphatases/phosphodiesterases on the move Crit. Rev. Biochem. Mol. Biol. 35 2000 393 432
5. J.W. Goding Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family Biochim. Biophys. Acta 1638 2003 1 19
6. R. Gijsbers Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases J. Biol. Chem. 276 2001 1361 1368
7. M. McDermott Phospholipase D Biochem. Cell Biol. 82 2004 225 253
8. A.S. Mildvan Structures and mechanisms of Nudix hydrolases Arch. Biochem. Biophys. 433 2005 129 143
9. B.K. Kishore Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling Am. J. Physiol. Renal Physiol. 288 2005 F1032 F1043
10. Y. Ohe Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain Biochem. Biophys. Res. Commun. 308 2003 719 725
11. J. Wu Pancreatic trypsin cleaves intestinal alkaline sphingomyelinase from mucosa and enhances the sphingomyelinase activity Am. J. Physiol. Gastrointest. Liver Physiol. 287 2004 G967 G973
12. V. Bello Characterization of a di-leucine-based signal in the cytoplasmic tail of the nucleotide-pyrophosphatase NPP1 that mediates basolateral targeting but not endocytosis Mol. Biol. Cell 12 2001 3004 3015
13. S.M. Vaingankar Subcellular targeting and function of osteoblast nucleotide pyrophosphatase phosphodiesterase 1 Am. J. Physiol. Cell Physiol. 286 2004 C1177 C1187
14. N.R. Meerson Intracellular traffic of the ecto-nucleotide pyrophosphatase/phosphodiesterase NPP3 to the apical plasma membrane of MDCK and Caco-2 cells: apical targeting occurs in the absence of N-glycosylation J. Cell Sci. 113 2000 4193 4202
15. C. Luquain Lysophosphatidic acid signaling: how a small lipid does big things Trends Biochem. Sci. 28 2003 377 383
16. G.B. Mills, and W.H. Moolenaar The emerging role of lysophosphatidic acid in cancer Nat. Rev. Cancer 3 2003 582 591
17. S. Jansen Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D J. Cell Sci. 118 2005 3081 3089
18. i and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression J. Bone Miner. Res. 18 2003 994 1004
19. R. Gijsbers Functional characterization of the non-catalytic ectodomains of the nucleotide pyrophosphatase/phosphodiesterase NPP1 Biochem. J. 371 2003 321 330
20. A. Cimpean Substrate-specifying determinants of the nucleotide pyrophosphatases/pyrophosphodiesterases NPP1 and NPP2 Biochem. J. 381 2004 71 77
21. M.A. Fox Phosphodiesterase-Iα/autotaxin controls cytoskeletal organization and FAK phosphorylation during myelination Mol. Cell. Neurosci. 27 2004 140 150
22. A. Zhou How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration Nat. Struct. Biol. 10 2003 541 544
23. R. Gijsbers The hydrolysis of lysophyospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site FEBS Lett. 538 2003 60 64
24. E. Koh Site-directed mutations in the tumor-associated cytokine, autotaxin, eliminate nucleotide phosphodiesterase, lysophospholipase D, and motogenic activities Cancer Res. 63 2003 2042 2045
25. J. Wu Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis Biochem. J. 386 2005 153 160
26. L.A. van Meeteren Inhibition of autotaxin by lysophosphatidic acid and sphingosine-1-phosphate J. Biol. Chem. 280 2005 21155 21161
27. R.A. Terkeltaub Inorganic pyrophosphate generation and disposition in pathophysiology Am. J. Physiol. Cell Physiol. 281 2001 C1 C11
28. D. Harmey Concerted regulation of inorganic pyrophosphate and osteopontin by Akp2, Enpp1, and Ank Am. J. Pathol. 164 2004 1199 1209
29. -/- mice Arterioscler. Thromb. Vasc. Biol. 25 2005 686 691
30. W. Wang Role of progressive ankylosis gene (ank) in cartilage mineralization Mol. Cell. Biol. 25 2005 312 323
31. M. Murshed Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone Genes Dev. 19 2005 1093 1104
32. K. Johnson Matrix vesicle plasma cell membrane glycoprotein-1 regulates mineralization by murine osteoblastic MC3T3 cells J. Bone Miner. Res. 14 1999 883 892
33. A. Okawa Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine Nat. Genet. 19 1998 271 273
34. L. Hessle Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization Proc. Natl. Acad. Sci. U. S. A. 99 2002 9445 9449
35. H.C. Anderson Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice Am. J. Pathol. 166 2005 1711 1720
36. F. Rutsch Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification Nat. Genet. 34 2003 379 381
37. N. Ruf The mutational spectrum of ENPP1 as arising after the analysis of 23 unrelated patients with generalized arterial calcification of infancy (GACI) Hum. Mutat. 25 2005 98 104
38. Y. Koshizuka Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine J. Bone Miner. Res. 17 2002 138 144
39. S. Hashimoto Chondrocyte-derived apoptotic bodies and calcification of articular cartilage Proc. Natl. Acad. Sci. U. S. A. 95 1998 3094 3099
40. K. Johnson Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification Arthritis Rheum. 44 2001 1071 1081
41. K. Johnson The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles J. Rheumatol. 28 2001 2681 2691
42. B.A. Maddux, and I.D. Goldfine Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor α-subunit Diabetes 49 2000 13 19
43. 121) Diabetes 50 2001 831 836
44. I.D. Goldfine Role of PC-1 in the etiology of insulin resistance Ann. N. Y. Acad. Sci. 892 1999 204 224
45. H. Sakoda No correlation of plasma cell 1 overexpression with insulin resistance in diabetic rats and 3T3-L1 adipocytes Diabetes 48 1999 1365 1371
46. H. Dong Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance Diabetes 54 2005 367 372
47. C. Pender Elevated plasma cell membrane glycoprotein levels and diminished insulin receptor autophosphorylation in obese, insulin-resistant rhesus monkeys Metabolism 51 2002 465 470
48. C. Menzaghi Insulin modulates PC-1 processing and recruitment in cultured human cells Am. J. Physiol. Endocrinol. Metab. 284 2003 E514 E520
49. L. Frittitta A cluster of three single nucleotide polymorphisms in the 3′-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities Diabetes 50 2001 1952 1955
50. N. Abate ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes Diabetes 54 2005 1207 1213
51. A. Tokumura Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase J. Biol. Chem. 277 2002 39436 39442
52. K. Sato Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources J. Neurochem. 92 2005 904 914
53. G. Ferry Autoaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation J. Biol. Chem. 278 2003 18162 18169
54. 1 J. Biol. Chem. 279 2004 17634 17639
55. I.D. Jung Cdc42 and Rac1 are necessary for autotaxin-induced tumor cell motility in A2058 melanoma cells FEBS Lett. 532 2002 351 356
56. H.Y. Lee Autotaxin promotes motility via G protein-coupled phosphoinositide 3-kinase γ in human melanoma cells FEBS Lett. 515 2002 137 140
57. W.H. Moolenaar The ins and outs of lysophosphatidic acid signaling Bioessays 26 2004 870 881
58. T. Clair Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate Cancer Res. 63 2003 5446 5453
59. D. Bächner Developmental expression analysis of murine autotaxin (ATX) Mech. Dev. 84 1999 121 125
60. S.W. Nam Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor Cancer Res. 61 2001 6938 6944
61. M. Simon Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor γ2 J. Biol. Chem. 280 2005 14656 14662
62. N. Fukushima LPA in neural cell development J. Cell. Biochem. 92 2004 993 1003
63. S.W. Nam Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells Oncogene 19 2000 241 247
64. S.Y. Yang Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells Clin. Exp. Metastasis 19 2002 603 608
65. A. Kehlen Expression, regulation and function of autotaxin in thyroid carcinomas Int. J. Cancer 109 2004 833 838
66. M. Umezo-Goto Lysophosphatidic acid production and action: validated targets in cancer? J. Cell. Biochem. 92 2004 1115 1140
67. M. Chen, and K.L. O'Connor Integrin α6β4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells Oncogene 24 2005 5125 5130
68. E.J. Black Microarray analysis identifies autotaxin, a tumour cell motility and angiogenic factor with lysophospholipase D activity, as a specific target of cell transformation by v-Jun Oncogene 23 2004 2357 2366
69. Baumforth, K.R. et al. Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin's lymphoma cells. Blood (in press)
70. 3-mediated lysophosphatidic acid signalling in embryo implantation and spacing Nature 435 2005 104 108
71. H. Bühring The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis Int. Arch. Allergy Immunol. 133 2004 317 329
72. D.G. Ebo In vitro allergy diagnosis: should we follow the flow? Clin. Exp. Allergy 34 2004 332 339
73. L.J. Scott Biochemical and molecular identification of distinct forms of alkaline phosphodiesterase I expressed on the apical and basolateral plasma membrane surfaces of rat hepatocytes Hepatology 25 1997 995 1002
74. P. Vollmayer Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases Eur. J. Biochem. 270 2003 2971 2978
75. K. Johnson Mediation of spontaneous knee osteoarthritis by progressive Chondrocyte ATP depletion in Hartley guinea pigs Arthritis Rheum. 50 2004 1216 1225