메뉴 건너뛰기




Volumn 5, Issue 2, 2010, Pages

Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE; INTERLEUKIN 6; INTERLEUKIN 8; OSTEOPONTIN; 3 ETHYL 1 PROPYL 8 (1 (3 TRIFLUOROMETHYLBENZYL) 1H PYRAZOL 4 YL) 3,7 DIHYDROPURINE 2,6 DIONE; 3-ETHYL-1-PROPYL-8-(1-(3-TRIFLUOROMETHYLBENZYL)-1H-PYRAZOL-4-YL)-3,7-DIHYDROPURINE-2,6-DIONE; ADENOSINE RECEPTOR; PURINE DERIVATIVE; PYRAZOLE DERIVATIVE;

EID: 77949518257     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009224     Document Type: Article
Times cited : (116)

References (51)
  • 1
    • 0031897876 scopus 로고    scopus 로고
    • Lung inflammation and fibrosis
    • HunninghakeGW
    • Ward PA, HunninghakeGW(1998) Lung inflammation and fibrosis. Am J Respir Crit Care Med 157: S123-129.
    • (1998) Am J Respir Crit Care Med , vol.157
    • Ward, P.A.1
  • 3
    • 0037305002 scopus 로고    scopus 로고
    • Too much of a good thing: Adenosine overload in adenosine-deaminase-deficient mice
    • Blackburn MR (2003) Too much of a good thing: adenosine overload in adenosine-deaminase-deficient mice. Trends Pharmacol Sci 24: 66-70.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 66-70
    • Blackburn, M.R.1
  • 5
    • 0036902490 scopus 로고    scopus 로고
    • Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma
    • Huszar E, Vass G, Vizi E, Csoma Z, Barat E, et al. (2002) Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma. Eur Respir J 20: 1393-1398.
    • (2002) Eur Respir J , vol.20 , pp. 1393-1398
    • Huszar, E.1    Vass, G.2    Vizi, E.3    Csoma, Z.4    Barat, E.5
  • 6
    • 0022999779 scopus 로고
    • Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma
    • Mann JS, Holgate ST, Renwick AG, Cushley MJ (1986) Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma. J Appl Physiol 61: 1667-1676.
    • (1986) J Appl Physiol , vol.61 , pp. 1667-1676
    • Mann, J.S.1    Holgate, S.T.2    Renwick, A.G.3    Cushley, M.J.4
  • 7
    • 65749092940 scopus 로고    scopus 로고
    • Adenosine signaling and the regulation of chronic lung disease
    • Zhou Y, Schneider DJ, Blackburn MR (2009) Adenosine signaling and the regulation of chronic lung disease. Pharmacol Ther 123: 105-116.
    • (2009) Pharmacol Ther , vol.123 , pp. 105-116
    • Zhou, Y.1    Schneider, D.J.2    Blackburn, M.R.3
  • 8
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm BB, AP IJ, Jacobson KA, Klotz KN, Linden J (2001) International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53: 527-552.
    • (2001) Pharmacol Rev , vol.53 , pp. 527-552
    • Fredholm, B.B.1    AP, I.J.2    Jacobson, K.A.3    Klotz, K.N.4    Linden, J.5
  • 9
    • 40349099333 scopus 로고    scopus 로고
    • Elevated expression of adenosine A1 receptor in bronchial biopsy specimens from asthmatic subjects
    • Brown RA, Clarke GW, Ledbetter CL, Hurle MJ, Denyer JC, et al. (2008) Elevated expression of adenosine A1 receptor in bronchial biopsy specimens from asthmatic subjects. Eur Respir J 31: 311-319.
    • (2008) Eur Respir J , vol.31 , pp. 311-319
    • Brown, R.A.1    Clarke, G.W.2    Ledbetter, C.L.3    Hurle, M.J.4    Denyer, J.C.5
  • 11
    • 32444448624 scopus 로고    scopus 로고
    • Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease
    • Varani K, Caramori G, Vincenzi F, Adcock I, Casolari P, et al. (2006) Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 173: 398-406.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 398-406
    • Varani, K.1    Caramori, G.2    Vincenzi, F.3    Adcock, I.4    Casolari, P.5
  • 14
    • 0033117460 scopus 로고    scopus 로고
    • Adenosine receptor ligands: Potential as therapeutic agents in asthma and COPD
    • Fozard JR, Hannon JP (1999) Adenosine receptor ligands: potential as therapeutic agents in asthma and COPD. Pulm Pharmacol Ther 12: 111-114.
    • (1999) Pulm Pharmacol Ther , vol.12 , pp. 111-114
    • Fozard, J.R.1    Hannon, J.P.2
  • 15
    • 0020655642 scopus 로고
    • Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects
    • Cushley MJ, Tattersfield AE, Holgate ST (1983) Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br J Clin Pharmacol 15: 161-165.
    • (1983) Br J Clin Pharmacol , vol.15 , pp. 161-165
    • Cushley, M.J.1    Tattersfield, A.E.2    Holgate, S.T.3
  • 16
    • 0027503167 scopus 로고
    • Airway responsiveness to adenosine 59-monophosphate in chronic obstructive pulmonary disease is determined by smoking
    • Oosterhoff Y, de Jong JW, Jansen MA, Koeter GH, Postma DS (1993) Airway responsiveness to adenosine 59-monophosphate in chronic obstructive pulmonary disease is determined by smoking. Am Rev Respir Dis 147: 553-558.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 553-558
    • Oosterhoff, Y.1    de Jong, J.W.2    Jansen, M.A.3    Koeter, G.H.4    Postma, D.S.5
  • 17
    • 0017801449 scopus 로고
    • Potentiation of mast cell mediator release by adenosine
    • Marquardt DL, Parker CW, Sullivan TJ (1978) Potentiation of mast cell mediator release by adenosine. J Immunol 120: 871-878.
    • (1978) J Immunol , vol.120 , pp. 871-878
    • Marquardt, D.L.1    Parker, C.W.2    Sullivan, T.J.3
  • 18
    • 0030588630 scopus 로고    scopus 로고
    • Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice
    • Hasko G, Szabo C, Nemeth ZH, Kvetan V, Pastores SM, et al. (1996) Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J Immunol 157: 4634-4640.
    • (1996) J Immunol , vol.157 , pp. 4634-4640
    • Hasko, G.1    Szabo, C.2    Nemeth, Z.H.3    Kvetan, V.4    Pastores, S.M.5
  • 19
    • 0022357102 scopus 로고
    • Adenosine-induced secretion in the canine trachea: Modification by methylxanthines and adenosine derivatives
    • Johnson HG, McNee ML (1985) Adenosine-induced secretion in the canine trachea: modification by methylxanthines and adenosine derivatives. Br J Pharmacol 86: 63-67.
    • (1985) Br J Pharmacol , vol.86 , pp. 63-67
    • Johnson, H.G.1    McNee, M.L.2
  • 20
    • 11144230939 scopus 로고    scopus 로고
    • Synergy between A2B adenosine receptors and hypoxia in activating human lung fibroblasts
    • Zhong H, Belardinelli L, Maa T, Zeng D (2005) Synergy between A2B adenosine receptors and hypoxia in activating human lung fibroblasts. Am J Respir Cell Mol Biol 32: 2-8.
    • (2005) Am J Respir Cell Mol Biol , vol.32 , pp. 2-8
    • Zhong, H.1    Belardinelli, L.2    Maa, T.3    Zeng, D.4
  • 21
    • 0028325787 scopus 로고
    • Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: Evidence for an inducible adenosine A1 receptor
    • Ali S, Mustafa SJ, Metzger WJ (1994) Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor. J Pharmacol Exp Ther 268: 1328-1334.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1328-1334
    • Ali, S.1    Mustafa, S.J.2    Metzger, W.J.3
  • 23
    • 0042388120 scopus 로고    scopus 로고
    • Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway
    • Blackburn MR, Lee CG, Young HW, Zhu Z, Chunn JL, et al. (2003) Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. J Clin Invest 112: 332-344.
    • (2003) J Clin Invest , vol.112 , pp. 332-344
    • Blackburn, M.R.1    Lee, C.G.2    Young, H.W.3    Zhu, Z.4    Chunn, J.L.5
  • 24
    • 33646407318 scopus 로고    scopus 로고
    • Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis
    • Ma B, Blackburn MR, Lee CG, Homer RJ, Liu W, et al. (2006) Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. J Clin Invest 116: 1274-1283.
    • (2006) J Clin Invest , vol.116 , pp. 1274-1283
    • Ma, B.1    Blackburn, M.R.2    Lee, C.G.3    Homer, R.J.4    Liu, W.5
  • 25
    • 33646074537 scopus 로고    scopus 로고
    • Ecto-5′-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury
    • Volmer JB, Thompson LF, Blackburn MR (2006) Ecto-5′-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury. J Immunol 176: 4449-4458.
    • (2006) J Immunol , vol.176 , pp. 4449-4458
    • Volmer, J.B.1    Thompson, L.F.2    Blackburn, M.R.3
  • 27
    • 0034679559 scopus 로고    scopus 로고
    • Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
    • Blackburn MR, Volmer JB, Thrasher JL, Zhong H, Crosby JR, et al. (2000) Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. J Exp Med 192: 159-170.
    • (2000) J Exp Med , vol.192 , pp. 159-170
    • Blackburn, M.R.1    Volmer, J.B.2    Thrasher, J.L.3    Zhong, H.4    Crosby, J.R.5
  • 28
    • 85047690674 scopus 로고    scopus 로고
    • A protective role for the A(1) adenosine receptor in adenosine-dependent pulmonary injury
    • Sun CX, Young HW, Molina JG, Volmer JB, Schnermann J, et al. (2005) A protective role for the A(1) adenosine receptor in adenosine-dependent pulmonary injury. J Clin Invest 115: 35-43.
    • (2005) J Clin Invest , vol.115 , pp. 35-43
    • Sun, C.X.1    Young, H.W.2    Molina, J.G.3    Volmer, J.B.4    Schnermann, J.5
  • 29
    • 22544450731 scopus 로고    scopus 로고
    • Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice
    • Chunn JL, Molina JG, Mi T, Xia Y, Kellems RE, et al. (2005) Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice. J Immunol 175: 1937-1946.
    • (2005) J Immunol , vol.175 , pp. 1937-1946
    • Chunn, J.L.1    Molina, J.G.2    Mi, T.3    Xia, Y.4    Kellems, R.E.5
  • 30
    • 33746666617 scopus 로고    scopus 로고
    • Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
    • Sun CX, Zhong H, Mohsenin A, Morschl E, Chunn JL, et al. (2006) Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury. J Clin Invest 116: 2173-2182.
    • (2006) J Clin Invest , vol.116 , pp. 2173-2182
    • Sun, C.X.1    Zhong, H.2    Mohsenin, A.3    Morschl, E.4    Chunn, J.L.5
  • 31
    • 3142754919 scopus 로고    scopus 로고
    • A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice
    • Young HW, Molina JG, Dimina D, Zhong H, Jacobson M, et al. (2004) A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice. J Immunol 173: 1380-1389.
    • (2004) J Immunol , vol.173 , pp. 1380-1389
    • Young, H.W.1    Molina, J.G.2    Dimina, D.3    Zhong, H.4    Jacobson, M.5
  • 32
    • 33646195495 scopus 로고    scopus 로고
    • Regulation of fibrosis by the immune system
    • Lupher ML Jr, Gallatin WM (2006) Regulation of fibrosis by the immune system. Adv Immunol 89: 245-288.
    • (2006) Adv Immunol , vol.89 , pp. 245-288
    • Lupher Jr, M.L.1    Gallatin, W.M.2
  • 33
    • 42049109309 scopus 로고    scopus 로고
    • What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis
    • Strieter RM (2008) What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis. Proc Am Thorac Soc 5: 305-310.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 305-310
    • Strieter, R.M.1
  • 34
    • 0028972108 scopus 로고
    • Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma
    • Feoktistov I, Biaggioni I (1995) Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest 96: 1979-1986.
    • (1995) J Clin Invest , vol.96 , pp. 1979-1986
    • Feoktistov, I.1    Biaggioni, I.2
  • 35
    • 2942560494 scopus 로고    scopus 로고
    • Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: An A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma
    • Ryzhov S, Goldstein AE, Matafonov A, Zeng D, Biaggioni I, et al. (2004) Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma. J Immunol 172: 7726-7733.
    • (2004) J Immunol , vol.172 , pp. 7726-7733
    • Ryzhov, S.1    Goldstein, A.E.2    Matafonov, A.3    Zeng, D.4    Biaggioni, I.5
  • 36
    • 38749118604 scopus 로고    scopus 로고
    • Effect of A2B adenosine receptor gene ablation on adenosine-dependent regulation of proinflammatory cytokines
    • Ryzhov S, Zaynagetdinov R, Goldstein AE, Novitskiy SV, Blackburn MR, et al. (2008) Effect of A2B adenosine receptor gene ablation on adenosine-dependent regulation of proinflammatory cytokines. J Pharmacol Exp Ther 324: 694-700.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 694-700
    • Ryzhov, S.1    Zaynagetdinov, R.2    Goldstein, A.E.3    Novitskiy, S.V.4    Blackburn, M.R.5
  • 37
    • 47249138181 scopus 로고    scopus 로고
    • Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells
    • Ryzhov S, Zaynagetdinov R, Goldstein AE, Novitskiy SV, Dikov MM, et al. (2008) Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells. J Immunol 180: 7212-7220.
    • (2008) J Immunol , vol.180 , pp. 7212-7220
    • Ryzhov, S.1    Zaynagetdinov, R.2    Goldstein, A.E.3    Novitskiy, S.V.4    Dikov, M.M.5
  • 38
    • 33745817034 scopus 로고    scopus 로고
    • The A2B adenosine receptor protects against inflammation and excessive vascular adhesion
    • Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, et al. (2006) The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest 116: 1913-1923.
    • (2006) J Clin Invest , vol.116 , pp. 1913-1923
    • Yang, D.1    Zhang, Y.2    Nguyen, H.G.3    Koupenova, M.4    Chauhan, A.K.5
  • 40
    • 0022589517 scopus 로고
    • Release of adenosine and its metabolites from activated human leucocytes
    • Mann JS, Renwick AG, Holgate ST (1986) Release of adenosine and its metabolites from activated human leucocytes. Clin Sci (Lond) 70: 461-468.
    • (1986) Clin Sci (Lond) , vol.70 , pp. 461-468
    • Mann, J.S.1    Renwick, A.G.2    Holgate, S.T.3
  • 41
    • 0036130498 scopus 로고    scopus 로고
    • Plasma adenosine concentration increases during exercise: A possible contributing factor in exercise-induced bronchoconstriction in asthma
    • Vizi E, Huszar E, Csoma Z, Boszormenyi-Nagy G, Barat E, et al. (2002) Plasma adenosine concentration increases during exercise: a possible contributing factor in exercise-induced bronchoconstriction in asthma. J Allergy Clin Immunol 109: 446-448.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 446-448
    • Vizi, E.1    Huszar, E.2    Csoma, Z.3    Boszormenyi-Nagy, G.4    Barat, E.5
  • 42
    • 33646452709 scopus 로고    scopus 로고
    • Adenosine regulation of cystic fibrosis transmembrane conductance regulator through prostenoids in airway epithelia
    • Li Y, Wang W, Parker W, Clancy JP (2006) Adenosine regulation of cystic fibrosis transmembrane conductance regulator through prostenoids in airway epithelia. Am J Respir Cell Mol Biol 34: 600-608.
    • (2006) Am J Respir Cell Mol Biol , vol.34 , pp. 600-608
    • Li, Y.1    Wang, W.2    Parker, W.3    Clancy, J.P.4
  • 43
    • 2442427376 scopus 로고    scopus 로고
    • Metabolism of P2 receptor agonists in human airways: Implications for mucociliary clearance and cystic fibrosis
    • Picher M, Burch LH, Boucher RC (2004) Metabolism of P2 receptor agonists in human airways: implications for mucociliary clearance and cystic fibrosis. J Biol Chem 279: 20234-20241.
    • (2004) J Biol Chem , vol.279 , pp. 20234-20241
    • Picher, M.1    Burch, L.H.2    Boucher, R.C.3
  • 44
    • 13444262230 scopus 로고    scopus 로고
    • Adenosine deaminase deficiency: Metabolic basis of immune deficiency and pulmonary inflammation
    • Blackburn MR, Kellems RE (2005) Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation. Adv Immunol 86: 1-41.
    • (2005) Adv Immunol , vol.86 , pp. 1-41
    • Blackburn, M.R.1    Kellems, R.E.2
  • 46
    • 0035887625 scopus 로고    scopus 로고
    • Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice
    • Chunn JL, Young HW, Banerjee SK, Colasurdo GN, Blackburn MR (2001) Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice. J Immunol 167: 4676-4685.
    • (2001) J Immunol , vol.167 , pp. 4676-4685
    • Chunn, J.L.1    Young, H.W.2    Banerjee, S.K.3    Colasurdo, G.N.4    Blackburn, M.R.5
  • 47
    • 51049101334 scopus 로고    scopus 로고
    • Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases
    • Hasko G, Linden J, Cronstein B, Pacher P (2008) Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 7: 759-770.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 759-770
    • Hasko, G.1    Linden, J.2    Cronstein, B.3    Pacher, P.4
  • 48
    • 34250770500 scopus 로고    scopus 로고
    • Adenosine, an endogenous distress signal, modulates tissue damage and repair
    • Fredholm BB (2007) Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ 14: 1315-1323.
    • (2007) Cell Death Differ , vol.14 , pp. 1315-1323
    • Fredholm, B.B.1
  • 50
    • 41349114840 scopus 로고    scopus 로고
    • A2B adenosine receptor dampens hypoxia-induced vascular leak
    • Eckle T, Faigle M, Grenz A, Laucher S, Thompson LF, et al. (2008) A2B adenosine receptor dampens hypoxia-induced vascular leak. Blood 111: 2024-2035.
    • (2008) Blood , vol.111 , pp. 2024-2035
    • Eckle, T.1    Faigle, M.2    Grenz, A.3    Laucher, S.4    Thompson, L.F.5
  • 51
    • 33947667794 scopus 로고    scopus 로고
    • Enhanced CXCL1 production and angiogenesis in adenosine-mediated lung disease
    • Mohsenin A, Burdick MD, Molina JG, Keane MP, Blackburn MR (2007) Enhanced CXCL1 production and angiogenesis in adenosine-mediated lung disease. Faseb J 21: 1026-1036.
    • (2007) Faseb J , vol.21 , pp. 1026-1036
    • Mohsenin, A.1    Burdick, M.D.2    Molina, J.G.3    Keane, M.P.4    Blackburn, M.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.