메뉴 건너뛰기




Volumn 17, Issue 4, 2011, Pages 188-196

Pain-relieving prospects for adenosine receptors and ectonucleotidases

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 IODOTUBERCIDIN; ACID PHOSPHATASE PROSTATE ISOENZYME; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE PHOSPHATE; ADENOSINE RECEPTOR; ATL 313; BVT 115959; CLONIDINE; CVT 3619; ECTO 5' NUCLEOTIDASE; ECTONUCLEOTIDASE; GW 493838; INO 8875; PENTOSTATIN; T 62; TRIPHOSPHOINOSITIDE; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER;

EID: 79954578322     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmed.2010.12.006     Document Type: Review
Times cited : (147)

References (94)
  • 1
    • 33644770260 scopus 로고    scopus 로고
    • Adenosine receptors as therapeutic targets
    • Jacobson K.A., Gao Z.G. Adenosine receptors as therapeutic targets. Nat. Rev. Drug Discov. 2006, 5:247-264.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 247-264
    • Jacobson, K.A.1    Gao, Z.G.2
  • 2
    • 0142185330 scopus 로고    scopus 로고
    • Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations
    • Schulte G., et al. Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations. Neuroscience 2003, 121:907-916.
    • (2003) Neuroscience , vol.121 , pp. 907-916
    • Schulte, G.1
  • 3
    • 0026396691 scopus 로고
    • Molecular cloning and characterization of a rat A1-adenosine receptor that is widely expressed in brain and spinal cord
    • Reppert S.M., et al. Molecular cloning and characterization of a rat A1-adenosine receptor that is widely expressed in brain and spinal cord. Mol. Endocrinol. 1991, 5:1037-1048.
    • (1991) Mol. Endocrinol. , vol.5 , pp. 1037-1048
    • Reppert, S.M.1
  • 4
    • 77957917696 scopus 로고    scopus 로고
    • Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: Involvement of the NO/cGMP/PKG/KATP signaling pathway
    • Lima F.O., et al. Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: Involvement of the NO/cGMP/PKG/KATP signaling pathway. Pain 2010, 151:506-515.
    • (2010) Pain , vol.151 , pp. 506-515
    • Lima, F.O.1
  • 5
    • 36349022149 scopus 로고    scopus 로고
    • Adenosine and ATP receptors
    • Sawynok J. Adenosine and ATP receptors. Handb. Exp. Pharmacol. 2007, 177:309-328.
    • (2007) Handb. Exp. Pharmacol. , vol.177 , pp. 309-328
    • Sawynok, J.1
  • 6
    • 23144453122 scopus 로고    scopus 로고
    • Clinical application of adenosine and ATP for pain control
    • Hayashida M., et al. Clinical application of adenosine and ATP for pain control. J. Anesth. 2005, 19:225-235.
    • (2005) J. Anesth. , vol.19 , pp. 225-235
    • Hayashida, M.1
  • 7
    • 0038243600 scopus 로고    scopus 로고
    • Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design
    • Lynch M.E., et al. Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design. Pain 2003, 103:111-117.
    • (2003) Pain , vol.103 , pp. 111-117
    • Lynch, M.E.1
  • 8
    • 0028987038 scopus 로고
    • An A1-selective adenosine agonist abolishes allodynia elicited by vibration and touch after intrathecal injection
    • Karlsten R., Gordh T. An A1-selective adenosine agonist abolishes allodynia elicited by vibration and touch after intrathecal injection. Anesth. Analg. 1995, 80:844-847.
    • (1995) Anesth. Analg. , vol.80 , pp. 844-847
    • Karlsten, R.1    Gordh, T.2
  • 9
    • 1442274901 scopus 로고    scopus 로고
    • Intrathecal but not intravenous opioids release adenosine from the spinal cord
    • Eisenach J.C., et al. Intrathecal but not intravenous opioids release adenosine from the spinal cord. J. Pain 2004, 5:64-68.
    • (2004) J. Pain , vol.5 , pp. 64-68
    • Eisenach, J.C.1
  • 10
    • 85052609862 scopus 로고    scopus 로고
    • Drug-enhanced spinal stimulation for pain: a new strategy
    • Lind G., et al. Drug-enhanced spinal stimulation for pain: a new strategy. Acta Neurochir. Suppl. 2007, 97:57-63.
    • (2007) Acta Neurochir. Suppl. , vol.97 , pp. 57-63
    • Lind, G.1
  • 11
    • 0025054477 scopus 로고
    • Direct cutaneous hyperalgesia induced by adenosine
    • Taiwo Y.O., Levine J.D. Direct cutaneous hyperalgesia induced by adenosine. Neuroscience 1990, 38:757-762.
    • (1990) Neuroscience , vol.38 , pp. 757-762
    • Taiwo, Y.O.1    Levine, J.D.2
  • 12
    • 5644220419 scopus 로고    scopus 로고
    • Neuropathic pain symptoms relative to overall pain rating
    • Backonja M.M., Stacey B. Neuropathic pain symptoms relative to overall pain rating. J. Pain 2004, 5:491-497.
    • (2004) J. Pain , vol.5 , pp. 491-497
    • Backonja, M.M.1    Stacey, B.2
  • 13
    • 74949100800 scopus 로고    scopus 로고
    • Unmasking the tonic-aversive state in neuropathic pain
    • King T., et al. Unmasking the tonic-aversive state in neuropathic pain. Nat. Neurosci. 2009, 12:1364-1366.
    • (2009) Nat. Neurosci. , vol.12 , pp. 1364-1366
    • King, T.1
  • 14
    • 0022930378 scopus 로고
    • Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue
    • Dolphin A.C., et al. Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue. J. Physiol. 1986, 373:47-61.
    • (1986) J. Physiol. , vol.373 , pp. 47-61
    • Dolphin, A.C.1
  • 15
    • 0028357658 scopus 로고
    • Adenosine acting at an A1 receptor decreases N-type calcium current in mouse motoneurons
    • Mynlieff M., Beam K.G. Adenosine acting at an A1 receptor decreases N-type calcium current in mouse motoneurons. J. Neurosci. 1994, 14:3628-3634.
    • (1994) J. Neurosci. , vol.14 , pp. 3628-3634
    • Mynlieff, M.1    Beam, K.G.2
  • 16
    • 77951652246 scopus 로고    scopus 로고
    • Ziconotide for treatment of severe chronic pain
    • Schmidtko A., et al. Ziconotide for treatment of severe chronic pain. Lancet 2010, 375:1569-1577.
    • (2010) Lancet , vol.375 , pp. 1569-1577
    • Schmidtko, A.1
  • 17
    • 33846582369 scopus 로고    scopus 로고
    • Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics
    • Martin T.J., et al. Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics. Anesthesiology 2007, 106:312-322.
    • (2007) Anesthesiology , vol.106 , pp. 312-322
    • Martin, T.J.1
  • 18
    • 0141738786 scopus 로고    scopus 로고
    • Intrathecal, but not intravenous adenosine reduces allodynia in patients with neuropathic pain
    • Eisenach J.C., et al. Intrathecal, but not intravenous adenosine reduces allodynia in patients with neuropathic pain. Pain 2003, 105:65-70.
    • (2003) Pain , vol.105 , pp. 65-70
    • Eisenach, J.C.1
  • 19
    • 38449122175 scopus 로고    scopus 로고
    • Adenosine A1 but not A2a receptor agonist reduces hyperalgesia caused by a surgical incision in rats: a pertussis toxin-sensitive G protein-dependent process
    • Zahn P.K., et al. Adenosine A1 but not A2a receptor agonist reduces hyperalgesia caused by a surgical incision in rats: a pertussis toxin-sensitive G protein-dependent process. Anesthesiology 2007, 107:797-806.
    • (2007) Anesthesiology , vol.107 , pp. 797-806
    • Zahn, P.K.1
  • 20
    • 70349845440 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pain
    • Basbaum A.I., et al. Cellular and molecular mechanisms of pain. Cell 2009, 139:267-284.
    • (2009) Cell , vol.139 , pp. 267-284
    • Basbaum, A.I.1
  • 21
    • 77952969125 scopus 로고    scopus 로고
    • Coding of facial expressions of pain in the laboratory mouse
    • Langford D.J., et al. Coding of facial expressions of pain in the laboratory mouse. Nat. Methods 2010, 7:447-449.
    • (2010) Nat. Methods , vol.7 , pp. 447-449
    • Langford, D.J.1
  • 22
    • 34547555788 scopus 로고    scopus 로고
    • Adenosine as a non-opioid analgesic in the perioperative setting
    • Gan T.J., Habib A.S. Adenosine as a non-opioid analgesic in the perioperative setting. Anesth. Analg. 2007, 105:487-494.
    • (2007) Anesth. Analg. , vol.105 , pp. 487-494
    • Gan, T.J.1    Habib, A.S.2
  • 23
    • 58149288597 scopus 로고    scopus 로고
    • Phase 2, double-blind, placebo-controlled, dose-response trial of intravenous adenosine for perioperative analgesia
    • Habib A.S., et al. Phase 2, double-blind, placebo-controlled, dose-response trial of intravenous adenosine for perioperative analgesia. Anesthesiology 2008, 109:1085-1091.
    • (2008) Anesthesiology , vol.109 , pp. 1085-1091
    • Habib, A.S.1
  • 24
    • 77955387987 scopus 로고    scopus 로고
    • Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate
    • Sowa N.A., et al. Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate. J. Neurosci. 2010, 30:10282-10293.
    • (2010) J. Neurosci. , vol.30 , pp. 10282-10293
    • Sowa, N.A.1
  • 25
    • 63449113568 scopus 로고    scopus 로고
    • MAP kinase and pain
    • Ji R.R., et al. MAP kinase and pain. Brain Res. Rev. 2009, 60:135-148.
    • (2009) Brain Res. Rev. , vol.60 , pp. 135-148
    • Ji, R.R.1
  • 26
    • 59349112493 scopus 로고    scopus 로고
    • Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats
    • Matsuka Y., et al. Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats. Mol. Pain 2008, 4:66.
    • (2008) Mol. Pain , vol.4 , pp. 66
    • Matsuka, Y.1
  • 27
    • 0032786637 scopus 로고    scopus 로고
    • Regulation of epidermal homeostasis through P2Y2 receptors
    • Dixon C.J., et al. Regulation of epidermal homeostasis through P2Y2 receptors. Br. J. Pharmacol. 1999, 127:1680-1686.
    • (1999) Br. J. Pharmacol. , vol.127 , pp. 1680-1686
    • Dixon, C.J.1
  • 28
    • 2942746282 scopus 로고    scopus 로고
    • Ca2+ waves in keratinocytes are transmitted to sensory neurons: the involvement of extracellular ATP and P2Y2 receptor activation
    • Koizumi S., et al. Ca2+ waves in keratinocytes are transmitted to sensory neurons: the involvement of extracellular ATP and P2Y2 receptor activation. Biochem. J. 2004, 380:329-338.
    • (2004) Biochem. J. , vol.380 , pp. 329-338
    • Koizumi, S.1
  • 29
    • 0029662016 scopus 로고    scopus 로고
    • P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation
    • Nakamura F., Strittmatter S.M. P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:10465-10470.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 10465-10470
    • Nakamura, F.1    Strittmatter, S.M.2
  • 30
    • 77955105496 scopus 로고    scopus 로고
    • Astrocytes control breathing through pH-dependent release of ATP
    • Gourine A.V., et al. Astrocytes control breathing through pH-dependent release of ATP. Science 2010, 329:571-575.
    • (2010) Science , vol.329 , pp. 571-575
    • Gourine, A.V.1
  • 31
    • 0037162496 scopus 로고    scopus 로고
    • Intercellular calcium signaling mediated by point-source burst release of ATP
    • Arcuino G., et al. Intercellular calcium signaling mediated by point-source burst release of ATP. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:9840-9845.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 9840-9845
    • Arcuino, G.1
  • 32
    • 38549168318 scopus 로고    scopus 로고
    • A central role of connexin 43 in hypoxic preconditioning
    • Lin J.H., et al. A central role of connexin 43 in hypoxic preconditioning. J. Neurosci. 2008, 28:681-695.
    • (2008) J. Neurosci. , vol.28 , pp. 681-695
    • Lin, J.H.1
  • 33
    • 44649092806 scopus 로고    scopus 로고
    • Connexin 43 hemichannels are permeable to ATP
    • Kang J., et al. Connexin 43 hemichannels are permeable to ATP. J. Neurosci. 2008, 28:4702-4711.
    • (2008) J. Neurosci. , vol.28 , pp. 4702-4711
    • Kang, J.1
  • 34
    • 29744451390 scopus 로고    scopus 로고
    • ATP release via anion channels
    • Sabirov R.Z., Okada Y. ATP release via anion channels. Purinergic Signal. 2005, 1:311-328.
    • (2005) Purinergic Signal. , vol.1 , pp. 311-328
    • Sabirov, R.Z.1    Okada, Y.2
  • 35
    • 44449149786 scopus 로고    scopus 로고
    • Identification of a vesicular nucleotide transporter
    • Sawada K., et al. Identification of a vesicular nucleotide transporter. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:5683-5686.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 5683-5686
    • Sawada, K.1
  • 36
    • 77958064327 scopus 로고    scopus 로고
    • Nonsynaptic communication through ATP release from volume-activated anion channels in axons
    • Fields R.D., Ni Y. Nonsynaptic communication through ATP release from volume-activated anion channels in axons. Sci. Signal. 2010, 3:ra73.
    • (2010) Sci. Signal. , vol.3
    • Fields, R.D.1    Ni, Y.2
  • 37
    • 77349106961 scopus 로고    scopus 로고
    • Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression
    • Sreedharan S., et al. Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression. BMC Genomics 2010, 11:17.
    • (2010) BMC Genomics , vol.11 , pp. 17
    • Sreedharan, S.1
  • 38
    • 33747410178 scopus 로고    scopus 로고
    • Ectonucleotidases in the nervous system
    • Zimmermann H. Ectonucleotidases in the nervous system. Novartis Found. Symp. 2006, 276:113-128.
    • (2006) Novartis Found. Symp. , vol.276 , pp. 113-128
    • Zimmermann, H.1
  • 39
    • 0030875738 scopus 로고    scopus 로고
    • Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus
    • Dunwiddie T.V., et al. Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus. J. Neurosci. 1997, 17:7673-7682.
    • (1997) J. Neurosci. , vol.17 , pp. 7673-7682
    • Dunwiddie, T.V.1
  • 40
    • 34250217010 scopus 로고    scopus 로고
    • Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance
    • Nakagawa T., et al. Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance. Neuroscience 2007, 147:445-455.
    • (2007) Neuroscience , vol.147 , pp. 445-455
    • Nakagawa, T.1
  • 41
    • 13144276331 scopus 로고    scopus 로고
    • Neuropathic pain and spinal microglia: a big problem from molecules in " small" glia
    • Tsuda M., et al. Neuropathic pain and spinal microglia: a big problem from molecules in " small" glia. Trends Neurosci. 2005, 28:101-107.
    • (2005) Trends Neurosci. , vol.28 , pp. 101-107
    • Tsuda, M.1
  • 42
    • 0028362318 scopus 로고
    • Potentiation of cAMP responses by metabotropic glutamate receptors depresses excitatory synaptic transmission by a kinase-independent mechanism
    • Gereau R.W., Conn P.J. Potentiation of cAMP responses by metabotropic glutamate receptors depresses excitatory synaptic transmission by a kinase-independent mechanism. Neuron 1994, 12:1121-1129.
    • (1994) Neuron , vol.12 , pp. 1121-1129
    • Gereau, R.W.1    Conn, P.J.2
  • 43
    • 0030715265 scopus 로고    scopus 로고
    • The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus
    • Brundege J.M., et al. The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus. Neuropharmacology 1997, 36:1201-1210.
    • (1997) Neuropharmacology , vol.36 , pp. 1201-1210
    • Brundege, J.M.1
  • 44
    • 0038689146 scopus 로고    scopus 로고
    • Adenosine in the spinal cord and periphery: release and regulation of pain
    • Sawynok J., Liu X.J. Adenosine in the spinal cord and periphery: release and regulation of pain. Prog. Neurobiol. 2003, 69:313-340.
    • (2003) Prog. Neurobiol. , vol.69 , pp. 313-340
    • Sawynok, J.1    Liu, X.J.2
  • 45
    • 0033995205 scopus 로고    scopus 로고
    • Therapeutic potential of adenosine kinase inhibitors
    • Kowaluk E.A., Jarvis M.F. Therapeutic potential of adenosine kinase inhibitors. Expert Opin. Investig. Drugs 2000, 9:551-564.
    • (2000) Expert Opin. Investig. Drugs , vol.9 , pp. 551-564
    • Kowaluk, E.A.1    Jarvis, M.F.2
  • 46
    • 13444273445 scopus 로고    scopus 로고
    • Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors
    • McGaraughty S., et al. Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors. Curr. Top. Med. Chem. 2005, 5:43-58.
    • (2005) Curr. Top. Med. Chem. , vol.5 , pp. 43-58
    • McGaraughty, S.1
  • 47
    • 53049093740 scopus 로고    scopus 로고
    • Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine
    • Zylka M.J., et al. Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine. Neuron 2008, 60:111-122.
    • (2008) Neuron , vol.60 , pp. 111-122
    • Zylka, M.J.1
  • 48
    • 77952506358 scopus 로고    scopus 로고
    • Prostatic acid phosphatase is expressed in peptidergic and nonpeptidergic nociceptive neurons of mice and rats
    • Taylor-Blake B., Zylka M.J. Prostatic acid phosphatase is expressed in peptidergic and nonpeptidergic nociceptive neurons of mice and rats. PLoS One 2010, 5:e8674.
    • (2010) PLoS One , vol.5
    • Taylor-Blake, B.1    Zylka, M.J.2
  • 49
    • 76649109206 scopus 로고    scopus 로고
    • Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits
    • Sowa N.A., et al. Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits. J. Neurosci. 2010, 30:2235-2244.
    • (2010) J. Neurosci. , vol.30 , pp. 2235-2244
    • Sowa, N.A.1
  • 50
    • 0024574194 scopus 로고
    • Morphine, capsaicin and K+ release purines from capsaicin-sensitive primary afferent nerve terminals in the spinal cord
    • Sweeney M.I., et al. Morphine, capsaicin and K+ release purines from capsaicin-sensitive primary afferent nerve terminals in the spinal cord. J. Pharmacol. Exp. Ther. 1989, 248:447-454.
    • (1989) J. Pharmacol. Exp. Ther. , vol.248 , pp. 447-454
    • Sweeney, M.I.1
  • 51
    • 0036465327 scopus 로고    scopus 로고
    • Effect of chronic and acute stress on ectonucleotidase activities in spinal cord
    • Torres I.L., et al. Effect of chronic and acute stress on ectonucleotidase activities in spinal cord. Physiol. Behav. 2002, 75:1-5.
    • (2002) Physiol. Behav. , vol.75 , pp. 1-5
    • Torres, I.L.1
  • 52
    • 0035169117 scopus 로고    scopus 로고
    • A novel transverse push-pull microprobe: in vitro characterization and in vivo demonstration of the enzymatic production of adenosine in the spinal cord dorsal horn
    • Patterson S.L., et al. A novel transverse push-pull microprobe: in vitro characterization and in vivo demonstration of the enzymatic production of adenosine in the spinal cord dorsal horn. J. Neurochem. 2001, 76:234-246.
    • (2001) J. Neurochem. , vol.76 , pp. 234-246
    • Patterson, S.L.1
  • 53
    • 77950655571 scopus 로고    scopus 로고
    • Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation
    • Sowa N.A., et al. Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation. Mol. Pain 2010, 6:20.
    • (2010) Mol. Pain , vol.6 , pp. 20
    • Sowa, N.A.1
  • 54
    • 12344273306 scopus 로고    scopus 로고
    • Increased nociceptive response in mice lacking the adenosine A1 receptor
    • Wu W.P., et al. Increased nociceptive response in mice lacking the adenosine A1 receptor. Pain 2005, 113:395-404.
    • (2005) Pain , vol.113 , pp. 395-404
    • Wu, W.P.1
  • 55
    • 0030593746 scopus 로고    scopus 로고
    • Altered sensory behaviors in mice following manipulation of endogenous spinal adenosine neurotransmission
    • Keil G.J., DeLander G.E. Altered sensory behaviors in mice following manipulation of endogenous spinal adenosine neurotransmission. Eur. J. Pharmacol. 1996, 312:7-14.
    • (1996) Eur. J. Pharmacol. , vol.312 , pp. 7-14
    • Keil, G.J.1    DeLander, G.E.2
  • 56
    • 77952954507 scopus 로고    scopus 로고
    • Excitatory synaptic transmission in the spinal substantia gelatinosa is under an inhibitory tone of endogenous adenosine
    • Tian L., et al. Excitatory synaptic transmission in the spinal substantia gelatinosa is under an inhibitory tone of endogenous adenosine. Neurosci. Lett. 2010, 477:28-32.
    • (2010) Neurosci. Lett. , vol.477 , pp. 28-32
    • Tian, L.1
  • 57
    • 77954624950 scopus 로고    scopus 로고
    • Neonatal morphine exposure alters E-NTPDase activity and gene expression pattern in spinal cord and cerebral cortex of rats
    • Rozisky J.R., et al. Neonatal morphine exposure alters E-NTPDase activity and gene expression pattern in spinal cord and cerebral cortex of rats. Eur. J. Pharmacol. 2010, 642:72-76.
    • (2010) Eur. J. Pharmacol. , vol.642 , pp. 72-76
    • Rozisky, J.R.1
  • 58
    • 64149093214 scopus 로고    scopus 로고
    • Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A1-adenosine receptors to mediate antinociception
    • Sowa N.A., et al. Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A1-adenosine receptors to mediate antinociception. PLoS One 2009, 4:e4248.
    • (2009) PLoS One , vol.4
    • Sowa, N.A.1
  • 59
    • 68349124954 scopus 로고    scopus 로고
    • Prostatic acid phosphatase, a neglected ectonucleotidase
    • Zimmermann H. Prostatic acid phosphatase, a neglected ectonucleotidase. Purinergic Signal. 2009, 5:273-275.
    • (2009) Purinergic Signal. , vol.5 , pp. 273-275
    • Zimmermann, H.1
  • 60
    • 34250160114 scopus 로고    scopus 로고
    • Alkaline phosphatases: structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes
    • Millan J.L. Alkaline phosphatases: structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes. Purinergic Signal. 2006, 2:335-341.
    • (2006) Purinergic Signal. , vol.2 , pp. 335-341
    • Millan, J.L.1
  • 61
    • 0020157753 scopus 로고
    • Secretion into and elimination from blood circulation of prostate specific acid phosphatase, measured by radioimmunoassay
    • Vihko P., et al. Secretion into and elimination from blood circulation of prostate specific acid phosphatase, measured by radioimmunoassay. J. Urol. 1982, 128:202-204.
    • (1982) J. Urol. , vol.128 , pp. 202-204
    • Vihko, P.1
  • 62
    • 46749141315 scopus 로고    scopus 로고
    • Ziconotide: an update and review
    • Williams J.A., et al. Ziconotide: an update and review. Expert Opin. Pharmacother. 2008, 9:1575-1583.
    • (2008) Expert Opin. Pharmacother. , vol.9 , pp. 1575-1583
    • Williams, J.A.1
  • 63
    • 0021691378 scopus 로고
    • Antinociceptive effects in mice after intrathecal injection of 5'-N-ethylcarboxamide adenosine
    • Post C. Antinociceptive effects in mice after intrathecal injection of 5'-N-ethylcarboxamide adenosine. Neurosci. Lett. 1984, 51:325-330.
    • (1984) Neurosci. Lett. , vol.51 , pp. 325-330
    • Post, C.1
  • 64
    • 85047694590 scopus 로고
    • Herpes zoster. The treatment and prevention of neuralgia with adenosine monophosphate
    • Sklar S.H., et al. Herpes zoster. The treatment and prevention of neuralgia with adenosine monophosphate. J. Am. Med. Assoc. 1985, 253:1427-1430.
    • (1985) J. Am. Med. Assoc. , vol.253 , pp. 1427-1430
    • Sklar, S.H.1
  • 65
    • 72249089979 scopus 로고    scopus 로고
    • Nucleoside-5'-monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-5'-nucleotidase
    • El-Tayeb A., et al. Nucleoside-5'-monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-5'-nucleotidase. J. Med. Chem. 2009, 52:7669-7677.
    • (2009) J. Med. Chem. , vol.52 , pp. 7669-7677
    • El-Tayeb, A.1
  • 66
    • 0029658136 scopus 로고    scopus 로고
    • Identification of potent P2Y-purinoceptor agonists that are derivatives of adenosine 5'-monophosphate
    • Boyer J.L., et al. Identification of potent P2Y-purinoceptor agonists that are derivatives of adenosine 5'-monophosphate. Br. J. Pharmacol. 1996, 118:1959-1964.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1959-1964
    • Boyer, J.L.1
  • 67
    • 77950838144 scopus 로고    scopus 로고
    • Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior
    • Malin S.A., Molliver D.C. Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior. Mol. Pain 2010, 6:21.
    • (2010) Mol. Pain , vol.6 , pp. 21
    • Malin, S.A.1    Molliver, D.C.2
  • 68
    • 31144434817 scopus 로고    scopus 로고
    • Constant darkness is a circadian metabolic signal in mammals
    • Zhang J., et al. Constant darkness is a circadian metabolic signal in mammals. Nature 2006, 439:340-343.
    • (2006) Nature , vol.439 , pp. 340-343
    • Zhang, J.1
  • 69
    • 77954224921 scopus 로고    scopus 로고
    • A role of erythrocytes in adenosine monophosphate initiation of hypometabolism in mammals
    • Daniels I.S., et al. A role of erythrocytes in adenosine monophosphate initiation of hypometabolism in mammals. J. Biol. Chem. 2010, 285:20716-20723.
    • (2010) J. Biol. Chem. , vol.285 , pp. 20716-20723
    • Daniels, I.S.1
  • 71
    • 48349135601 scopus 로고    scopus 로고
    • Neural mechanism underlying acupuncture analgesia
    • Zhao Z.Q. Neural mechanism underlying acupuncture analgesia. Prog. Neurobiol. 2008, 85:355-375.
    • (2008) Prog. Neurobiol. , vol.85 , pp. 355-375
    • Zhao, Z.Q.1
  • 72
    • 63249113317 scopus 로고    scopus 로고
    • Acupuncture: what does the most reliable evidence tell us?
    • Ernst E. Acupuncture: what does the most reliable evidence tell us?. J. Pain Symptom Manage. 2009, 37:709-714.
    • (2009) J. Pain Symptom Manage. , vol.37 , pp. 709-714
    • Ernst, E.1
  • 73
    • 77954137780 scopus 로고    scopus 로고
    • Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture
    • Goldman N., et al. Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat. Neurosci. 2010, 13:883-888.
    • (2010) Nat. Neurosci. , vol.13 , pp. 883-888
    • Goldman, N.1
  • 74
    • 0031029783 scopus 로고    scopus 로고
    • Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal
    • Aley K.O., Levine J.D. Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal. J. Neurosci. 1997, 17:735-744.
    • (1997) J. Neurosci. , vol.17 , pp. 735-744
    • Aley, K.O.1    Levine, J.D.2
  • 75
    • 0028722705 scopus 로고
    • Involvement of purines in analgesia produced by weak electro-acupuncture
    • 54
    • Liu C., et al. Involvement of purines in analgesia produced by weak electro-acupuncture. Zhen Ci Yan Jiu 1994, 19:59-62. 54.
    • (1994) Zhen Ci Yan Jiu , vol.19 , pp. 59-62
    • Liu, C.1
  • 76
    • 77954131687 scopus 로고    scopus 로고
    • Needling adenosine receptors for pain relief
    • Zylka M.J. Needling adenosine receptors for pain relief. Nat. Neurosci. 2010, 13:783-784.
    • (2010) Nat. Neurosci. , vol.13 , pp. 783-784
    • Zylka, M.J.1
  • 77
    • 53749084409 scopus 로고    scopus 로고
    • Phospholipase C mediated modulation of TRPV1 channels
    • Rohacs T., et al. Phospholipase C mediated modulation of TRPV1 channels. Mol. Neurobiol. 2008, 37:153-163.
    • (2008) Mol. Neurobiol. , vol.37 , pp. 153-163
    • Rohacs, T.1
  • 78
    • 70449369578 scopus 로고    scopus 로고
    • Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain
    • Loram L.C., et al. Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain. J. Neurosci. 2009, 29:14015-14025.
    • (2009) J. Neurosci. , vol.29 , pp. 14015-14025
    • Loram, L.C.1
  • 79
    • 0030440984 scopus 로고    scopus 로고
    • Pharmacology of the spinal adenosine receptor which mediates the antiallodynic action of intrathecal adenosine agonists
    • Lee Y.W., Yaksh T.L. Pharmacology of the spinal adenosine receptor which mediates the antiallodynic action of intrathecal adenosine agonists. J. Pharmacol. Exp. Ther. 1996, 277:1642-1648.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1642-1648
    • Lee, Y.W.1    Yaksh, T.L.2
  • 80
    • 0031914926 scopus 로고    scopus 로고
    • Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat
    • Poon A., Sawynok J. Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat. Pain 1998, 74:235-245.
    • (1998) Pain , vol.74 , pp. 235-245
    • Poon, A.1    Sawynok, J.2
  • 81
    • 67649797862 scopus 로고    scopus 로고
    • Adenosine A2A receptor mediates microglial process retraction
    • Orr A.G., et al. Adenosine A2A receptor mediates microglial process retraction. Nat. Neurosci. 2009, 12:872-878.
    • (2009) Nat. Neurosci. , vol.12 , pp. 872-878
    • Orr, A.G.1
  • 82
    • 33947225356 scopus 로고    scopus 로고
    • Physiological roles for ecto-5'-nucleotidase (CD73)
    • Colgan S.P., et al. Physiological roles for ecto-5'-nucleotidase (CD73). Purinergic Signal. 2006, 2:351-360.
    • (2006) Purinergic Signal. , vol.2 , pp. 351-360
    • Colgan, S.P.1
  • 83
    • 34547095781 scopus 로고    scopus 로고
    • Prostatic acid phosphatase is not a prostate specific target
    • Quintero I.B., et al. Prostatic acid phosphatase is not a prostate specific target. Cancer Res. 2007, 67:6549-6554.
    • (2007) Cancer Res. , vol.67 , pp. 6549-6554
    • Quintero, I.B.1
  • 84
    • 29144502951 scopus 로고    scopus 로고
    • Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer
    • Veeramani S., et al. Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer. Endocr. Relat. Can. 2005, 12:805-822.
    • (2005) Endocr. Relat. Can. , vol.12 , pp. 805-822
    • Veeramani, S.1
  • 85
    • 70349306892 scopus 로고    scopus 로고
    • A1 adenosine receptor antagonists, agonists, and allosteric enhancers
    • Kiesman W.F., et al. A1 adenosine receptor antagonists, agonists, and allosteric enhancers. Handb. Exp. Pharmacol. 2009, 193:25-58.
    • (2009) Handb. Exp. Pharmacol. , vol.193 , pp. 25-58
    • Kiesman, W.F.1
  • 86
    • 19344374252 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain
    • Schaddelee M.P., et al. Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain. Eur. J. Pharmacol. 2005, 514:131-140.
    • (2005) Eur. J. Pharmacol. , vol.514 , pp. 131-140
    • Schaddelee, M.P.1
  • 87
    • 0031801494 scopus 로고    scopus 로고
    • Selectivity of action of 8-alkylamino analogues of N6-cyclopentyladenosine in vivo: haemodynamic versus anti-lipolytic responses in rats
    • van Schaick E.A., et al. Selectivity of action of 8-alkylamino analogues of N6-cyclopentyladenosine in vivo: haemodynamic versus anti-lipolytic responses in rats. Br. J. Pharmacol. 1998, 124:607-618.
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 607-618
    • van Schaick, E.A.1
  • 88
    • 28244477635 scopus 로고    scopus 로고
    • Phylogenetic analysis reveals a novel protein family closely related to adenosine deaminase
    • Maier S.A., et al. Phylogenetic analysis reveals a novel protein family closely related to adenosine deaminase. J. Mol. Evol. 2005, 61:776-794.
    • (2005) J. Mol. Evol. , vol.61 , pp. 776-794
    • Maier, S.A.1
  • 89
    • 38349168981 scopus 로고    scopus 로고
    • The extracellular adenosine deaminase growth factor, ADGF/CECR1, plays a role in Xenopus embryogenesis via the adenosine/P1 receptor
    • Iijima R., et al. The extracellular adenosine deaminase growth factor, ADGF/CECR1, plays a role in Xenopus embryogenesis via the adenosine/P1 receptor. J. Biol. Chem. 2008, 283:2255-2264.
    • (2008) J. Biol. Chem. , vol.283 , pp. 2255-2264
    • Iijima, R.1
  • 90
    • 26844457398 scopus 로고    scopus 로고
    • Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity
    • Zavialov A.V., Engstrom A. Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity. Biochem. J. 2005, 391:51-57.
    • (2005) Biochem. J. , vol.391 , pp. 51-57
    • Zavialov, A.V.1    Engstrom, A.2
  • 91
    • 0038511040 scopus 로고    scopus 로고
    • Ecto-AMP deaminase blunts the ATP-derived adenosine A2A receptor facilitation of acetylcholine release at rat motor nerve endings
    • Magalhaes-Cardoso M.T., et al. Ecto-AMP deaminase blunts the ATP-derived adenosine A2A receptor facilitation of acetylcholine release at rat motor nerve endings. J. Physiol. 2003, 549:399-408.
    • (2003) J. Physiol. , vol.549 , pp. 399-408
    • Magalhaes-Cardoso, M.T.1
  • 92
    • 0028823743 scopus 로고
    • Modulation of adenosine release from rat spinal cord by adenosine deaminase and adenosine kinase inhibitors
    • Golembiowska K., et al. Modulation of adenosine release from rat spinal cord by adenosine deaminase and adenosine kinase inhibitors. Brain Res. 1995, 699:315-320.
    • (1995) Brain Res. , vol.699 , pp. 315-320
    • Golembiowska, K.1
  • 93
    • 0030426817 scopus 로고    scopus 로고
    • Effects of iodotubercidin on adenosine kinase activity and nucleoside transport in DDT1 MF-2 smooth muscle cells
    • Parkinson F.E., Geiger J.D. Effects of iodotubercidin on adenosine kinase activity and nucleoside transport in DDT1 MF-2 smooth muscle cells. J. Pharmacol. Exp. Ther. 1996, 277:1397-1401.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1397-1401
    • Parkinson, F.E.1    Geiger, J.D.2
  • 94
    • 0035159420 scopus 로고    scopus 로고
    • Nucleoside transporter subtype expression: effects on potency of adenosine kinase inhibitors
    • Sinclair C.J., et al. Nucleoside transporter subtype expression: effects on potency of adenosine kinase inhibitors. Br. J. Pharmacol. 2001, 134:1037-1044.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 1037-1044
    • Sinclair, C.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.