-
1
-
-
70350418625
-
MTOR signaling at a glance
-
Laplante M., Sabatini D.M. mTOR signaling at a glance. J Cell Sci 2009, 122:3589-3594.
-
(2009)
J Cell Sci
, vol.122
, pp. 3589-3594
-
-
Laplante, M.1
Sabatini, D.M.2
-
2
-
-
0036753494
-
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
-
Loewith R., Jacinto E., Wullschleger S., Lorberg A., Crespo J.L., Bonenfant D., et al. Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 2002, 10:457-468.
-
(2002)
Mol Cell
, vol.10
, pp. 457-468
-
-
Loewith, R.1
Jacinto, E.2
Wullschleger, S.3
Lorberg, A.4
Crespo, J.L.5
Bonenfant, D.6
-
3
-
-
0037623417
-
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR
-
Kim D.H., Sarbassov D.D., Ali S.M., Latek R.R., Guntur K.V., Erdjument-Bromage H., et al. GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003, 11:895-904.
-
(2003)
Mol Cell
, vol.11
, pp. 895-904
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
Latek, R.R.4
Guntur, K.V.5
Erdjument-Bromage, H.6
-
4
-
-
67349241955
-
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
-
Peterson T.R., Laplante M., Thoreen C.C., Sancak Y., Kang S.A., Kuehl W.M., et al. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell 2009, 137:873-886.
-
(2009)
Cell
, vol.137
, pp. 873-886
-
-
Peterson, T.R.1
Laplante, M.2
Thoreen, C.C.3
Sancak, Y.4
Kang, S.A.5
Kuehl, W.M.6
-
5
-
-
0037178786
-
MTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim D.H., Sarbassov D.D., Ali S.M., King J.E., Latek R.R., Erdjument-Bromage H., et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002, 110:163-175.
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
-
6
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
Hara K., Maruki Y., Long X., Yoshino K., Oshiro N., Hidayat S., et al. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 2002, 110:177-189.
-
(2002)
Cell
, vol.110
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.4
Oshiro, N.5
Hidayat, S.6
-
7
-
-
34547099855
-
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding
-
Wang L., Harris T.E., Roth R.A., Lawrence J.C. PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding. J Biol Chem 2007, 282:20036-20044.
-
(2007)
J Biol Chem
, vol.282
, pp. 20036-20044
-
-
Wang, L.1
Harris, T.E.2
Roth, R.A.3
Lawrence, J.C.4
-
8
-
-
34547133519
-
The proline-rich Akt substrate of 40kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1
-
Oshiro N., Takahashi R., Yoshino K., Tanimura K., Nakashima A., Eguchi S., et al. The proline-rich Akt substrate of 40kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1. J Biol Chem 2007, 282:20329-20339.
-
(2007)
J Biol Chem
, vol.282
, pp. 20329-20339
-
-
Oshiro, N.1
Takahashi, R.2
Yoshino, K.3
Tanimura, K.4
Nakashima, A.5
Eguchi, S.6
-
9
-
-
34548359244
-
PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex
-
Fonseca B.D., Smith E.M., Lee V.H., MacKintosh C., Proud C.G. PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex. J Biol Chem 2007, 282:24514-24524.
-
(2007)
J Biol Chem
, vol.282
, pp. 24514-24524
-
-
Fonseca, B.D.1
Smith, E.M.2
Lee, V.H.3
MacKintosh, C.4
Proud, C.G.5
-
10
-
-
84896706986
-
Characterization of the raptor/4E-BP1 interaction by chemical cross-linking coupled with mass spectrometry analysis
-
Coffman K., Yang B., Lu J., Tetlow A.L., Pelliccio E., Lu S., et al. Characterization of the raptor/4E-BP1 interaction by chemical cross-linking coupled with mass spectrometry analysis. J Biol Chem 2014, 289:4723-4734.
-
(2014)
J Biol Chem
, vol.289
, pp. 4723-4734
-
-
Coffman, K.1
Yang, B.2
Lu, J.3
Tetlow, A.L.4
Pelliccio, E.5
Lu, S.6
-
11
-
-
41649101570
-
The binding of PRAS40 to 14-3-3 proteins is not required for activation of mTORC1 signalling by phorbol esters/ERK
-
Fonseca B.D., Lee V.H., Proud C.G. The binding of PRAS40 to 14-3-3 proteins is not required for activation of mTORC1 signalling by phorbol esters/ERK. Biochem J 2008, 411:141-149.
-
(2008)
Biochem J
, vol.411
, pp. 141-149
-
-
Fonseca, B.D.1
Lee, V.H.2
Proud, C.G.3
-
12
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
Sarbassov D.D., Ali S.M., Kim D.H., Guertin D.A., Latek R.R., Erdjument-Bromage H., et al. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 2004, 14:1296-1302.
-
(2004)
Curr Biol
, vol.14
, pp. 1296-1302
-
-
Sarbassov, D.D.1
Ali, S.M.2
Kim, D.H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
-
13
-
-
33748471980
-
MSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s
-
Frias M.A., Thoreen C.C., Jaffe J.D., Schroder W., Sculley T., Carr S.A., et al. mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Curr Biol 2006, 16:1865-1870.
-
(2006)
Curr Biol
, vol.16
, pp. 1865-1870
-
-
Frias, M.A.1
Thoreen, C.C.2
Jaffe, J.D.3
Schroder, W.4
Sculley, T.5
Carr, S.A.6
-
14
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto E., Facchinetti V., Liu D., Soto N., Wei S., Jung S.Y., et al. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 2006, 127:125-137.
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
-
15
-
-
34548509880
-
PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling
-
Woo S.Y., Kim D.H., Jun C.B., Kim Y.M., Haar E.V., Lee S.I., et al. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling. J Biol Chem 2007, 282:25604-25612.
-
(2007)
J Biol Chem
, vol.282
, pp. 25604-25612
-
-
Woo, S.Y.1
Kim, D.H.2
Jun, C.B.3
Kim, Y.M.4
Haar, E.V.5
Lee, S.I.6
-
16
-
-
34347210090
-
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
-
Pearce L.R., Huang X., Boudeau J., Pawlowski R., Wullschleger S., Deak M., et al. Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Biochem J 2007, 405:513-522.
-
(2007)
Biochem J
, vol.405
, pp. 513-522
-
-
Pearce, L.R.1
Huang, X.2
Boudeau, J.3
Pawlowski, R.4
Wullschleger, S.5
Deak, M.6
-
17
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov D.D., Ali S.M., Sengupta S., Sheen J.H., Hsu P.P., Bagley A.F., et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 2006, 22:159-168.
-
(2006)
Mol Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
-
18
-
-
0030716488
-
Regulation of eIF-4E BP1 phosphorylation by mTOR
-
Hara K., Yonezawa K., Kozlowski M.T., Sugimoto T., Andrabi K., Weng Q.P., et al. Regulation of eIF-4E BP1 phosphorylation by mTOR. J Biol Chem 1997, 272:26457-26463.
-
(1997)
J Biol Chem
, vol.272
, pp. 26457-26463
-
-
Hara, K.1
Yonezawa, K.2
Kozlowski, M.T.3
Sugimoto, T.4
Andrabi, K.5
Weng, Q.P.6
-
19
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett P.E., Barrow R.K., Cohen N.A., Snyder S.H., Sabatini D.M. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc Natl Acad Sci U S A 1998, 95:1432-1437.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Barrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
20
-
-
84861843696
-
A mechanistic overview of translation initiation in eukaryotes
-
Aitken C.E., Lorsch J.R. A mechanistic overview of translation initiation in eukaryotes. Nat Struct Mol Biol 2012, 19:568-576.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 568-576
-
-
Aitken, C.E.1
Lorsch, J.R.2
-
21
-
-
0028126506
-
PHAS-I as a link between mitogen-activated protein kinase and translation initiation
-
Lin T.A., Kong X., Haystead T.A., Pause A., Belsham G., Sonenberg N., et al. PHAS-I as a link between mitogen-activated protein kinase and translation initiation. Science 1994, 266:653-656.
-
(1994)
Science
, vol.266
, pp. 653-656
-
-
Lin, T.A.1
Kong, X.2
Haystead, T.A.3
Pause, A.4
Belsham, G.5
Sonenberg, N.6
-
22
-
-
0028034233
-
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function
-
Pause A., Belsham G.J., Gingras A.C., Donze O., Lin T.A., Lawrence J.C., et al. Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function. Nature 1994, 371:762-767.
-
(1994)
Nature
, vol.371
, pp. 762-767
-
-
Pause, A.1
Belsham, G.J.2
Gingras, A.C.3
Donze, O.4
Lin, T.A.5
Lawrence, J.C.6
-
23
-
-
0027936088
-
Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes
-
Haystead T.A., Haystead C.M., Hu C., Lin T.A., Lawrence J.C. Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes. J Biol Chem 1994, 269:23185-23191.
-
(1994)
J Biol Chem
, vol.269
, pp. 23185-23191
-
-
Haystead, T.A.1
Haystead, C.M.2
Hu, C.3
Lin, T.A.4
Lawrence, J.C.5
-
24
-
-
0028222129
-
Molecular cloning and tissue distribution of PHAS-I, an intracellular target for insulin and growth factors
-
Hu C., Pang S., Kong X., Velleca M., Lawrence J.C. Molecular cloning and tissue distribution of PHAS-I, an intracellular target for insulin and growth factors. Proc Natl Acad Sci U S A 1994, 91:3730-3734.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3730-3734
-
-
Hu, C.1
Pang, S.2
Kong, X.3
Velleca, M.4
Lawrence, J.C.5
-
25
-
-
0028819463
-
Further characterization of the acid-soluble phosphoprotein (SDS/PAGE apparent molecular mass of 22kDa) in rat fat-cells by peptide sequencing and immuno-analysis: effects of insulin and isoprenaline
-
Diggle T.A., Bloomberg G.B., Denton R.M. Further characterization of the acid-soluble phosphoprotein (SDS/PAGE apparent molecular mass of 22kDa) in rat fat-cells by peptide sequencing and immuno-analysis: effects of insulin and isoprenaline. Biochem J 1995, 306(Pt 1):135-139.
-
(1995)
Biochem J
, vol.306
, pp. 135-139
-
-
Diggle, T.A.1
Bloomberg, G.B.2
Denton, R.M.3
-
26
-
-
0029300425
-
Characterisation of a novel 22kDa phosphoprotein which may be important in insulin action
-
Diggle T.A., Denton R.M. Characterisation of a novel 22kDa phosphoprotein which may be important in insulin action. Biochem Soc Trans 1995, 23:209S.
-
(1995)
Biochem Soc Trans
, vol.23
, pp. 209S
-
-
Diggle, T.A.1
Denton, R.M.2
-
27
-
-
0032577691
-
4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family
-
Poulin F., Gingras A.C., Olsen H., Chevalier S., Sonenberg N. 4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family. J Biol Chem 1998, 273:14002-14007.
-
(1998)
J Biol Chem
, vol.273
, pp. 14002-14007
-
-
Poulin, F.1
Gingras, A.C.2
Olsen, H.3
Chevalier, S.4
Sonenberg, N.5
-
28
-
-
0035498939
-
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
-
Gingras A.C., Raught B., Gygi S.P., Niedzwiecka A., Miron M., Burley S.K., et al. Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes Dev 2001, 15:2852-2864.
-
(2001)
Genes Dev
, vol.15
, pp. 2852-2864
-
-
Gingras, A.C.1
Raught, B.2
Gygi, S.P.3
Niedzwiecka, A.4
Miron, M.5
Burley, S.K.6
-
29
-
-
0035312747
-
Regulation of translation initiation by FRAP/mTOR
-
Gingras A.C., Raught B., Sonenberg N. Regulation of translation initiation by FRAP/mTOR. Genes Dev 2001, 15:807-826.
-
(2001)
Genes Dev
, vol.15
, pp. 807-826
-
-
Gingras, A.C.1
Raught, B.2
Sonenberg, N.3
-
30
-
-
0037192868
-
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites
-
Herbert T.P., Tee A.R., Proud C.G. The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites. J Biol Chem 2002, 277:11591-11596.
-
(2002)
J Biol Chem
, vol.277
, pp. 11591-11596
-
-
Herbert, T.P.1
Tee, A.R.2
Proud, C.G.3
-
31
-
-
0033153166
-
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
-
Gingras A.C., Gygi S.P., Raught B., Polakiewicz R.D., Abraham R.T., Hoekstra M.F., et al. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism. Genes Dev 1999, 13:1422-1437.
-
(1999)
Genes Dev
, vol.13
, pp. 1422-1437
-
-
Gingras, A.C.1
Gygi, S.P.2
Raught, B.3
Polakiewicz, R.D.4
Abraham, R.T.5
Hoekstra, M.F.6
-
32
-
-
84856229054
-
Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E
-
Siddiqui N., Tempel W., Nedyalkova L., Volpon L., Wernimont A.K., Osborne M.J., et al. Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E. J Mol Biol 2012, 415:781-792.
-
(2012)
J Mol Biol
, vol.415
, pp. 781-792
-
-
Siddiqui, N.1
Tempel, W.2
Nedyalkova, L.3
Volpon, L.4
Wernimont, A.K.5
Osborne, M.J.6
-
33
-
-
0348111466
-
Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E
-
Ferguson G., Mothe-Satney I., Lawrence J.C. Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E. J Biol Chem 2003, 278:47459-47465.
-
(2003)
J Biol Chem
, vol.278
, pp. 47459-47465
-
-
Ferguson, G.1
Mothe-Satney, I.2
Lawrence, J.C.3
-
34
-
-
84897611292
-
Rapamycin-insensitive mTORC1 activity controls eIF4E:4E-BP1 binding
-
Livingstone M., Bidinosti M. Rapamycin-insensitive mTORC1 activity controls eIF4E:4E-BP1 binding. F1000Research 2012, 1:4.
-
(2012)
F1000Research
, vol.1
, pp. 4
-
-
Livingstone, M.1
Bidinosti, M.2
-
35
-
-
65549145048
-
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
-
Thoreen C.C., Kang S.A., Chang J.W., Liu Q., Zhang J., Gao Y., et al. An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J Biol Chem 2009, 284:8023-8032.
-
(2009)
J Biol Chem
, vol.284
, pp. 8023-8032
-
-
Thoreen, C.C.1
Kang, S.A.2
Chang, J.W.3
Liu, Q.4
Zhang, J.5
Gao, Y.6
-
36
-
-
61349141302
-
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
-
Feldman M.E., Apsel B., Uotila A., Loewith R., Knight Z.A., Ruggero D., et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol 2009, 7:e38.
-
(2009)
PLoS Biol
, vol.7
, pp. e38
-
-
Feldman, M.E.1
Apsel, B.2
Uotila, A.3
Loewith, R.4
Knight, Z.A.5
Ruggero, D.6
-
37
-
-
67650312583
-
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
-
Garcia-Martinez J.M., Moran J., Clarke R.G., Gray A., Cosulich S.C., Chresta C.M., et al. Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR). Biochem J 2009, 421:29-42.
-
(2009)
Biochem J
, vol.421
, pp. 29-42
-
-
Garcia-Martinez, J.M.1
Moran, J.2
Clarke, R.G.3
Gray, A.4
Cosulich, S.C.5
Chresta, C.M.6
-
38
-
-
75149112670
-
AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity
-
Chresta C.M., Davies B.R., Hickson I., Harding T., Cosulich S., Critchlow S.E., et al. AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity. Cancer Res 2010, 70:288-298.
-
(2010)
Cancer Res
, vol.70
, pp. 288-298
-
-
Chresta, C.M.1
Davies, B.R.2
Hickson, I.3
Harding, T.4
Cosulich, S.5
Critchlow, S.E.6
-
39
-
-
84861212263
-
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling
-
Fonseca B.D., Diering G.H., Bidinosti M.A., Dalal K., Alain T., Balgi A.D., et al. Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling. J Biol Chem 2012, 287:17530-17545.
-
(2012)
J Biol Chem
, vol.287
, pp. 17530-17545
-
-
Fonseca, B.D.1
Diering, G.H.2
Bidinosti, M.A.3
Dalal, K.4
Alain, T.5
Balgi, A.D.6
-
40
-
-
0030013407
-
Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat-cells
-
Diggle T.A., Moule S.K., Avison M.B., Flynn A., Foulstone E.J., Proud C.G., et al. Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat-cells. Biochem J 1996, 316(Pt 2):447-453.
-
(1996)
Biochem J
, vol.316
, pp. 447-453
-
-
Diggle, T.A.1
Moule, S.K.2
Avison, M.B.3
Flynn, A.4
Foulstone, E.J.5
Proud, C.G.6
-
41
-
-
84862777192
-
The translational landscape of mTOR signalling steers cancer initiation and metastasis
-
Hsieh A.C., Liu Y., Edlind M.P., Ingolia N.T., Janes M.R., Sher A., et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature 2012, 485:55-61.
-
(2012)
Nature
, vol.485
, pp. 55-61
-
-
Hsieh, A.C.1
Liu, Y.2
Edlind, M.P.3
Ingolia, N.T.4
Janes, M.R.5
Sher, A.6
-
42
-
-
84860527756
-
A unifying model for mTORC1-mediated regulation of mRNA translation
-
Thoreen C.C., Chantranupong L., Keys H.R., Wang T., Gray N.S., Sabatini D.M. A unifying model for mTORC1-mediated regulation of mRNA translation. Nature 2012, 485:109-113.
-
(2012)
Nature
, vol.485
, pp. 109-113
-
-
Thoreen, C.C.1
Chantranupong, L.2
Keys, H.R.3
Wang, T.4
Gray, N.S.5
Sabatini, D.M.6
-
43
-
-
77952967459
-
MTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
-
Dowling R.J., Topisirovic I., Alain T., Bidinosti M., Fonseca B.D., Petroulakis E., et al. mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. Science 2010, 328:1172-1176.
-
(2010)
Science
, vol.328
, pp. 1172-1176
-
-
Dowling, R.J.1
Topisirovic, I.2
Alain, T.3
Bidinosti, M.4
Fonseca, B.D.5
Petroulakis, E.6
-
44
-
-
70350494540
-
P53-dependent translational control of senescence and transformation via 4E-BPs
-
Petroulakis E., Parsyan A., Dowling R.J., LeBacquer O., Martineau Y., Bidinosti M., et al. p53-dependent translational control of senescence and transformation via 4E-BPs. Cancer Cell 2009, 16:439-446.
-
(2009)
Cancer Cell
, vol.16
, pp. 439-446
-
-
Petroulakis, E.1
Parsyan, A.2
Dowling, R.J.3
LeBacquer, O.4
Martineau, Y.5
Bidinosti, M.6
-
45
-
-
0036181011
-
Caspase cleavage of initiation factor 4E-binding protein 1 yields a dominant inhibitor of cap-dependent translation and reveals a novel regulatory motif
-
Tee A.R., Proud C.G. Caspase cleavage of initiation factor 4E-binding protein 1 yields a dominant inhibitor of cap-dependent translation and reveals a novel regulatory motif. Mol Cell Biol 2002, 22:1674-1683.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1674-1683
-
-
Tee, A.R.1
Proud, C.G.2
-
46
-
-
77953499323
-
Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain
-
Bidinosti M., Martineau Y., Frank F., Sonenberg N. Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain. J Biol Chem 2010, 285:19402-19408.
-
(2010)
J Biol Chem
, vol.285
, pp. 19402-19408
-
-
Bidinosti, M.1
Martineau, Y.2
Frank, F.3
Sonenberg, N.4
-
47
-
-
77949554923
-
Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission
-
Bidinosti M., Ran I., Sanchez-Carbente M.R., Martineau Y., Gingras A.C., Gkogkas C., et al. Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission. Mol Cell 2010, 37:797-808.
-
(2010)
Mol Cell
, vol.37
, pp. 797-808
-
-
Bidinosti, M.1
Ran, I.2
Sanchez-Carbente, M.R.3
Martineau, Y.4
Gingras, A.C.5
Gkogkas, C.6
-
48
-
-
0021732172
-
Preferential stimulation of rabbit alpha globin mRNA translation by a cap-binding protein complex
-
Sarkar G., Edery I., Gallo R., Sonenberg N. Preferential stimulation of rabbit alpha globin mRNA translation by a cap-binding protein complex. Biochim Biophys Acta 1984, 783:122-129.
-
(1984)
Biochim Biophys Acta
, vol.783
, pp. 122-129
-
-
Sarkar, G.1
Edery, I.2
Gallo, R.3
Sonenberg, N.4
-
49
-
-
0026723117
-
MRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E
-
Koromilas A.E., Lazaris-Karatzas A., Sonenberg N. mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E. EMBO J 1992, 11:4153-4158.
-
(1992)
EMBO J
, vol.11
, pp. 4153-4158
-
-
Koromilas, A.E.1
Lazaris-Karatzas, A.2
Sonenberg, N.3
-
50
-
-
0029830792
-
Expression of an ornithine decarboxylase dominant-negative mutant reverses eukaryotic initiation factor 4E-induced cell transformation
-
Shantz L.M., Coleman C.S., Pegg A.E. Expression of an ornithine decarboxylase dominant-negative mutant reverses eukaryotic initiation factor 4E-induced cell transformation. Cancer Res 1996, 56:5136-5140.
-
(1996)
Cancer Res
, vol.56
, pp. 5136-5140
-
-
Shantz, L.M.1
Coleman, C.S.2
Pegg, A.E.3
-
51
-
-
0030011284
-
Regulation of ornithine decarboxylase in a transformed cell line that overexpresses translation initiation factor eIF-4E
-
Shantz L.M., Hu R.H., Pegg A.E. Regulation of ornithine decarboxylase in a transformed cell line that overexpresses translation initiation factor eIF-4E. Cancer Res 1996, 56:3265-3269.
-
(1996)
Cancer Res
, vol.56
, pp. 3265-3269
-
-
Shantz, L.M.1
Hu, R.H.2
Pegg, A.E.3
-
52
-
-
0030041884
-
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
-
Rousseau D., Kaspar R., Rosenwald I., Gehrke L., Sonenberg N. Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. Proc Natl Acad Sci U S A 1996, 93:1065-1070.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1065-1070
-
-
Rousseau, D.1
Kaspar, R.2
Rosenwald, I.3
Gehrke, L.4
Sonenberg, N.5
-
53
-
-
0025834130
-
Insulin induction of ornithine decarboxylase. Importance of mRNA secondary structure and phosphorylation of eucaryotic initiation factors eIF-4B and eIF-4E
-
Manzella J.M., Rychlik W., Rhoads R.E., Hershey J.W., Blackshear P.J. Insulin induction of ornithine decarboxylase. Importance of mRNA secondary structure and phosphorylation of eucaryotic initiation factors eIF-4B and eIF-4E. J Biol Chem 1991, 266:2383-2389.
-
(1991)
J Biol Chem
, vol.266
, pp. 2383-2389
-
-
Manzella, J.M.1
Rychlik, W.2
Rhoads, R.E.3
Hershey, J.W.4
Blackshear, P.J.5
-
54
-
-
0032580332
-
Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA
-
Pyronnet S., Gingras A.C., Bouisson M., Kowalski-Chauvel A., Seva C., Vaysse N., et al. Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA. Oncogene 1998, 16:2219-2227.
-
(1998)
Oncogene
, vol.16
, pp. 2219-2227
-
-
Pyronnet, S.1
Gingras, A.C.2
Bouisson, M.3
Kowalski-Chauvel, A.4
Seva, C.5
Vaysse, N.6
-
55
-
-
0029967638
-
Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis
-
Kevil C.G., De Benedetti A., Payne D.K., Coe L.L., Laroux F.S., Alexander J.S. Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis. Int J Cancer 1996, 65:785-790.
-
(1996)
Int J Cancer
, vol.65
, pp. 785-790
-
-
Kevil, C.G.1
De Benedetti, A.2
Payne, D.K.3
Coe, L.L.4
Laroux, F.S.5
Alexander, J.S.6
-
56
-
-
33847217892
-
A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation
-
Prabhu S., Saadat D., Zhang M., Halbur L., Fruehauf J.P., Ong S.T. A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation. Oncogene 2007, 26:1188-1200.
-
(2007)
Oncogene
, vol.26
, pp. 1188-1200
-
-
Prabhu, S.1
Saadat, D.2
Zhang, M.3
Halbur, L.4
Fruehauf, J.P.5
Ong, S.T.6
-
57
-
-
84939884427
-
MTORC1 drives HIF-1alpha and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3
-
Epub. ahead of print
-
Dodd K.M., Yang J., Shen M.H., Sampson J.R., Tee A.R. mTORC1 drives HIF-1alpha and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3. Oncogene 2014, Epub. ahead of print.
-
(2014)
Oncogene
-
-
Dodd, K.M.1
Yang, J.2
Shen, M.H.3
Sampson, J.R.4
Tee, A.R.5
-
58
-
-
34250755685
-
Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation
-
Mamane Y., Petroulakis E., Martineau Y., Sato T.A., Larsson O., Rajasekhar V.K., et al. Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation. PLoS ONE 2007, 2:e242.
-
(2007)
PLoS ONE
, vol.2
, pp. e242
-
-
Mamane, Y.1
Petroulakis, E.2
Martineau, Y.3
Sato, T.A.4
Larsson, O.5
Rajasekhar, V.K.6
-
59
-
-
0029166967
-
Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels
-
Rosenwald I.B., Kaspar R., Rousseau D., Gehrke L., Leboulch P., Chen J.J., et al. Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels. J Biol Chem 1995, 270:21176-21180.
-
(1995)
J Biol Chem
, vol.270
, pp. 21176-21180
-
-
Rosenwald, I.B.1
Kaspar, R.2
Rousseau, D.3
Gehrke, L.4
Leboulch, P.5
Chen, J.J.6
-
60
-
-
0034624746
-
Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1
-
Tan A., Bitterman P., Sonenberg N., Peterson M., Polunovsky V. Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1. Oncogene 2000, 19:1437-1447.
-
(2000)
Oncogene
, vol.19
, pp. 1437-1447
-
-
Tan, A.1
Bitterman, P.2
Sonenberg, N.3
Peterson, M.4
Polunovsky, V.5
-
61
-
-
33749987326
-
Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure
-
Larsson O., Perlman D.M., Fan D., Reilly C.S., Peterson M., Dahlgren C., et al. Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Res 2006, 34:4375-4386.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 4375-4386
-
-
Larsson, O.1
Perlman, D.M.2
Fan, D.3
Reilly, C.S.4
Peterson, M.5
Dahlgren, C.6
-
62
-
-
62549134121
-
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
-
Ingolia N.T., Ghaemmaghami S., Newman J.R., Weissman J.S. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 2009, 324:218-223.
-
(2009)
Science
, vol.324
, pp. 218-223
-
-
Ingolia, N.T.1
Ghaemmaghami, S.2
Newman, J.R.3
Weissman, J.S.4
-
63
-
-
84861872213
-
Distinct perturbation of the translatome by the antidiabetic drug metformin
-
Larsson O., Morita M., Topisirovic I., Alain T., Blouin M.J., Pollak M., et al. Distinct perturbation of the translatome by the antidiabetic drug metformin. Proc Natl Acad Sci U S A 2012, 109:8977-8982.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 8977-8982
-
-
Larsson, O.1
Morita, M.2
Topisirovic, I.3
Alain, T.4
Blouin, M.J.5
Pollak, M.6
-
64
-
-
0028207001
-
Rapamycin selectively represses translation of the polypyrimidine tract mRNA family
-
Jefferies H.B., Reinhard C., Kozma S.C., Thomas G. Rapamycin selectively represses translation of the polypyrimidine tract mRNA family. Proc Natl Acad Sci U S A 1994, 91:4441-4445.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 4441-4445
-
-
Jefferies, H.B.1
Reinhard, C.2
Kozma, S.C.3
Thomas, G.4
-
65
-
-
0028032355
-
Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins
-
Terada N., Patel H.R., Takase K., Kohno K., Nairn A.C., Gelfand E.W. Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. Proc Natl Acad Sci U S A. 1994, 91(24):11477-11481.
-
(1994)
Proc Natl Acad Sci U S A.
, vol.91
, Issue.24
, pp. 11477-11481
-
-
Terada, N.1
Patel, H.R.2
Takase, K.3
Kohno, K.4
Nairn, A.C.5
Gelfand, E.W.6
-
66
-
-
0035200856
-
Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation
-
Tang H., Hornstein E., Stolovich M., Levy G., Livingstone M., Templeton D., et al. Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation. Mol Cell Biol 2001, 21:8671-8683.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8671-8683
-
-
Tang, H.1
Hornstein, E.2
Stolovich, M.3
Levy, G.4
Livingstone, M.5
Templeton, D.6
-
67
-
-
0036889291
-
Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation
-
Stolovich M., Tang H., Hornstein E., Levy G., Cohen R., Bae S.S., et al. Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation. Mol Cell Biol 2002, 22:8101-8113.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8101-8113
-
-
Stolovich, M.1
Tang, H.2
Hornstein, E.3
Levy, G.4
Cohen, R.5
Bae, S.S.6
-
68
-
-
59249097362
-
The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner
-
Patursky-Polischuk I., Stolovich-Rain M., Hausner-Hanochi M., Kasir J., Cybulski N., Avruch J., et al. The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner. Mol Cell Biol 2009, 29:640-649.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 640-649
-
-
Patursky-Polischuk, I.1
Stolovich-Rain, M.2
Hausner-Hanochi, M.3
Kasir, J.4
Cybulski, N.5
Avruch, J.6
-
69
-
-
84901700198
-
Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner
-
Miloslavski R., Cohen E., Avraham A., Iluz Y., Hayouka Z., Kasir J., et al. Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner. J Mol Cell Biol 2014, 6(3):255-266.
-
(2014)
J Mol Cell Biol
, vol.6
, Issue.3
, pp. 255-266
-
-
Miloslavski, R.1
Cohen, E.2
Avraham, A.3
Iluz, Y.4
Hayouka, Z.5
Kasir, J.6
-
70
-
-
44649193565
-
The RNA polymerase II core promoter - the gateway to transcription
-
Juven-Gershon T., Hsu J.Y., Theisen J.W., Kadonaga J.T. The RNA polymerase II core promoter - the gateway to transcription. Curr Opin Cell Biol 2008, 20:253-259.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 253-259
-
-
Juven-Gershon, T.1
Hsu, J.Y.2
Theisen, J.W.3
Kadonaga, J.T.4
-
71
-
-
0026323221
-
Oligopyrimidine tract at the 5' end of mammalian ribosomal protein mRNAs is required for their translational control
-
Levy S., Avni D., Hariharan N., Perry R.P., Meyuhas O. Oligopyrimidine tract at the 5' end of mammalian ribosomal protein mRNAs is required for their translational control. Proc Natl Acad Sci U S A 1991, 88:3319-3323.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 3319-3323
-
-
Levy, S.1
Avni, D.2
Hariharan, N.3
Perry, R.P.4
Meyuhas, O.5
-
72
-
-
0033761629
-
Synthesis of the translational apparatus is regulated at the translational level
-
Meyuhas O. Synthesis of the translational apparatus is regulated at the translational level. Eur J Biochem 2000, 267:6321-6330.
-
(2000)
Eur J Biochem
, vol.267
, pp. 6321-6330
-
-
Meyuhas, O.1
-
73
-
-
0026591514
-
Translational regulation of ribosomal protein synthesis in Xenopus cultured cells: mRNA relocation between polysomes and RNP during nutritional shifts
-
Loreni F., Amaldi F. Translational regulation of ribosomal protein synthesis in Xenopus cultured cells: mRNA relocation between polysomes and RNP during nutritional shifts. Eur J Biochem 1992, 205:1027-1032.
-
(1992)
Eur J Biochem
, vol.205
, pp. 1027-1032
-
-
Loreni, F.1
Amaldi, F.2
-
74
-
-
0020320668
-
Regulation of ribosomal protein mRNA content and translation in growth-stimulated mouse fibroblasts
-
Geyer P.K., Meyuhas O., Perry R.P., Johnson L.F. Regulation of ribosomal protein mRNA content and translation in growth-stimulated mouse fibroblasts. Mol Cell Biol 1982, 2:685-693.
-
(1982)
Mol Cell Biol
, vol.2
, pp. 685-693
-
-
Geyer, P.K.1
Meyuhas, O.2
Perry, R.P.3
Johnson, L.F.4
-
75
-
-
84860805752
-
Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis
-
Huo Y., Iadevaia V., Yao Z., Kelly I., Cosulich S., Guichard S., et al. Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis. Biochem J 2012, 444:141-151.
-
(2012)
Biochem J
, vol.444
, pp. 141-151
-
-
Huo, Y.1
Iadevaia, V.2
Yao, Z.3
Kelly, I.4
Cosulich, S.5
Guichard, S.6
-
76
-
-
0031588899
-
Cellular nucleic acid binding protein binds a conserved region of the 5' UTR of Xenopus laevis ribosomal protein mRNAs
-
Pellizzoni L., Lotti F., Maras B., Pierandrei-Amaldi P. Cellular nucleic acid binding protein binds a conserved region of the 5' UTR of Xenopus laevis ribosomal protein mRNAs. J Mol Biol 1997, 267:264-275.
-
(1997)
J Mol Biol
, vol.267
, pp. 264-275
-
-
Pellizzoni, L.1
Lotti, F.2
Maras, B.3
Pierandrei-Amaldi, P.4
-
77
-
-
34548035869
-
Identification of AUF1 as a rapamycin-responsive binding protein to the 5'-terminal oligopyrimidine element of mRNAs
-
Kakegawa T., Ohuchi N., Hayakawa A., Hirata S., Matsuda M., Kogure K., et al. Identification of AUF1 as a rapamycin-responsive binding protein to the 5'-terminal oligopyrimidine element of mRNAs. Arch Biochem Biophys 2007, 465:274-281.
-
(2007)
Arch Biochem Biophys
, vol.465
, pp. 274-281
-
-
Kakegawa, T.1
Ohuchi, N.2
Hayakawa, A.3
Hirata, S.4
Matsuda, M.5
Kogure, K.6
-
78
-
-
0034255406
-
La protein has a positive effect on the translation of TOP mRNAs in vivo
-
Crosio C., Boyl P.P., Loreni F., Pierandrei-Amaldi P., Amaldi F. La protein has a positive effect on the translation of TOP mRNAs in vivo. Nucleic Acids Res 2000, 28:2927-2934.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 2927-2934
-
-
Crosio, C.1
Boyl, P.P.2
Loreni, F.3
Pierandrei-Amaldi, P.4
Amaldi, F.5
-
79
-
-
0041315722
-
La protein is associated with terminal oligopyrimidine mRNAs in actively translating polysomes
-
Cardinali B., Carissimi C., Gravina P., Pierandrei-Amaldi P. La protein is associated with terminal oligopyrimidine mRNAs in actively translating polysomes. J Biol Chem 2003, 278:35145-35151.
-
(2003)
J Biol Chem
, vol.278
, pp. 35145-35151
-
-
Cardinali, B.1
Carissimi, C.2
Gravina, P.3
Pierandrei-Amaldi, P.4
-
80
-
-
80053625750
-
Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR
-
Damgaard C.K., Lykke-Andersen J. Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR. Genes Dev 2011, 25:2057-2068.
-
(2011)
Genes Dev
, vol.25
, pp. 2057-2068
-
-
Damgaard, C.K.1
Lykke-Andersen, J.2
-
81
-
-
84893912480
-
Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation
-
Tcherkezian J., Cargnello M., Romeo Y., Huttlin E.L., Lavoie G., Gygi S.P., et al. Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation. Genes Dev 2014, 28:357-371.
-
(2014)
Genes Dev
, vol.28
, pp. 357-371
-
-
Tcherkezian, J.1
Cargnello, M.2
Romeo, Y.3
Huttlin, E.L.4
Lavoie, G.5
Gygi, S.P.6
-
82
-
-
84879690536
-
LARP1 specifically recognizes the 3' terminus of poly(A) mRNA
-
Aoki K., Adachi S., Homoto M., Kusano H., Koike K., Natsume T. LARP1 specifically recognizes the 3' terminus of poly(A) mRNA. FEBS Lett 2013, 587:2173-2178.
-
(2013)
FEBS Lett
, vol.587
, pp. 2173-2178
-
-
Aoki, K.1
Adachi, S.2
Homoto, M.3
Kusano, H.4
Koike, K.5
Natsume, T.6
-
83
-
-
0025986847
-
Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini
-
Grove J.R., Banerjee P., Balasubramanyam A., Coffer P.J., Price D.J., Avruch J., et al. Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. Mol Cell Biol 1991, 11:5541-5550.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 5541-5550
-
-
Grove, J.R.1
Banerjee, P.2
Balasubramanyam, A.3
Coffer, P.J.4
Price, D.J.5
Avruch, J.6
-
84
-
-
0028276966
-
Differential subcellular localisation of two isoforms of p70 S6 protein kinase
-
Coffer P.J., Woodgett J.R. Differential subcellular localisation of two isoforms of p70 S6 protein kinase. Biochem Biophys Res Commun 1994, 198:780-786.
-
(1994)
Biochem Biophys Res Commun
, vol.198
, pp. 780-786
-
-
Coffer, P.J.1
Woodgett, J.R.2
-
85
-
-
0028175455
-
Nuclear localization of p85s6k: functional requirement for entry into S phase
-
Reinhard C., Fernandez A., Lamb N.J., Thomas G. Nuclear localization of p85s6k: functional requirement for entry into S phase. EMBO J 1994, 13:1557-1565.
-
(1994)
EMBO J
, vol.13
, pp. 1557-1565
-
-
Reinhard, C.1
Fernandez, A.2
Lamb, N.J.3
Thomas, G.4
-
86
-
-
80455155177
-
Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR
-
Rosner M., Hengstschlager M. Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR. Oncogene 2011, 30:4509-4522.
-
(2011)
Oncogene
, vol.30
, pp. 4509-4522
-
-
Rosner, M.1
Hengstschlager, M.2
-
87
-
-
84862768818
-
P70 S6K1 nuclear localization depends on its mTOR-mediated phosphorylation at T389, but not on its kinase activity towards S6
-
Rosner M., Schipany K., Hengstschlager M. p70 S6K1 nuclear localization depends on its mTOR-mediated phosphorylation at T389, but not on its kinase activity towards S6. Amino Acids 2012, 42:2251-2256.
-
(2012)
Amino Acids
, vol.42
, pp. 2251-2256
-
-
Rosner, M.1
Schipany, K.2
Hengstschlager, M.3
-
88
-
-
33847630730
-
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
-
Karni R., de Stanchina E., Lowe S.W., Sinha R., Mu D., Krainer A.R. The gene encoding the splicing factor SF2/ASF is a proto-oncogene. Nat Struct Mol Biol 2007, 14:185-193.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 185-193
-
-
Karni, R.1
de Stanchina, E.2
Lowe, S.W.3
Sinha, R.4
Mu, D.5
Krainer, A.R.6
-
89
-
-
84873170809
-
S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1
-
Ben-Hur V., Denichenko P., Siegfried Z., Maimon A., Krainer A., Davidson B., et al. S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1. Cell reports 2013, 3:103-115.
-
(2013)
Cell reports
, vol.3
, pp. 103-115
-
-
Ben-Hur, V.1
Denichenko, P.2
Siegfried, Z.3
Maimon, A.4
Krainer, A.5
Davidson, B.6
-
90
-
-
0026757270
-
An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase
-
Mukhopadhyay N.K., Price D.J., Kyriakis J.M., Pelech S., Sanghera J., Avruch J. An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase. J Biol Chem 1992, 267:3325-3335.
-
(1992)
J Biol Chem
, vol.267
, pp. 3325-3335
-
-
Mukhopadhyay, N.K.1
Price, D.J.2
Kyriakis, J.M.3
Pelech, S.4
Sanghera, J.5
Avruch, J.6
-
91
-
-
27744569843
-
MTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
Holz M.K., Ballif B.A., Gygi S.P., Blenis J. mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell 2005, 123:569-580.
-
(2005)
Cell
, vol.123
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
92
-
-
84891047861
-
S6K2: the neglected S6 kinase family member
-
Pardo O.E., Seckl M.J. S6K2: the neglected S6 kinase family member. Front Oncol 2013, 3:191.
-
(2013)
Front Oncol
, vol.3
, pp. 191
-
-
Pardo, O.E.1
Seckl, M.J.2
-
93
-
-
0032538890
-
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase
-
Shima H., Pende M., Chen Y., Fumagalli S., Thomas G., Kozma S.C. Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase. EMBO J 1998, 17:6649-6659.
-
(1998)
EMBO J
, vol.17
, pp. 6649-6659
-
-
Shima, H.1
Pende, M.2
Chen, Y.3
Fumagalli, S.4
Thomas, G.5
Kozma, S.C.6
-
94
-
-
0033539154
-
Characterization of S6K2, a novel kinase homologous to S6K1
-
Lee-Fruman K.K., Kuo C.J., Lippincott J., Terada N., Blenis J. Characterization of S6K2, a novel kinase homologous to S6K1. Oncogene 1999, 18:5108-5114.
-
(1999)
Oncogene
, vol.18
, pp. 5108-5114
-
-
Lee-Fruman, K.K.1
Kuo, C.J.2
Lippincott, J.3
Terada, N.4
Blenis, J.5
-
95
-
-
78650239404
-
Functions and regulation of the 70kDa ribosomal S6 kinases
-
Fenton T.R., Gout I.T. Functions and regulation of the 70kDa ribosomal S6 kinases. Int J Biochem Cell Biol 2011, 43:47-59.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 47-59
-
-
Fenton, T.R.1
Gout, I.T.2
-
96
-
-
11144356304
-
S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
-
Pende M., Um S.H., Mieulet V., Sticker M., Goss V.L., Mestan J., et al. S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol Cell Biol 2004, 24:3112-3124.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 3112-3124
-
-
Pende, M.1
Um, S.H.2
Mieulet, V.3
Sticker, M.4
Goss, V.L.5
Mestan, J.6
-
97
-
-
0023726116
-
Identification of the 40 S ribosomal protein S6 phosphorylation sites induced by cycloheximide
-
Krieg J., Hofsteenge J., Thomas G. Identification of the 40 S ribosomal protein S6 phosphorylation sites induced by cycloheximide. J Biol Chem 1988, 263:11473-11477.
-
(1988)
J Biol Chem
, vol.263
, pp. 11473-11477
-
-
Krieg, J.1
Hofsteenge, J.2
Thomas, G.3
-
98
-
-
24944464482
-
Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis
-
Ruvinsky I., Sharon N., Lerer T., Cohen H., Stolovich-Rain M., Nir T., et al. Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis. Genes Dev 2005, 19:2199-2211.
-
(2005)
Genes Dev
, vol.19
, pp. 2199-2211
-
-
Ruvinsky, I.1
Sharon, N.2
Lerer, T.3
Cohen, H.4
Stolovich-Rain, M.5
Nir, T.6
-
99
-
-
84858228734
-
Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy
-
Perl A.E., Kasner M.T., Shank D., Luger S.M., Carroll M. Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy. Clin Cancer Res 2012, 18:1716-1725.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1716-1725
-
-
Perl, A.E.1
Kasner, M.T.2
Shank, D.3
Luger, S.M.4
Carroll, M.5
-
100
-
-
42149192536
-
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains
-
Suzuki C., Garces R.G., Edmonds K.A., Hiller S., Hyberts S.G., Marintchev A., et al. PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains. Proc Natl Acad Sci U S A 2008, 105:3274-3279.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3274-3279
-
-
Suzuki, C.1
Garces, R.G.2
Edmonds, K.A.3
Hiller, S.4
Hyberts, S.G.5
Marintchev, A.6
-
101
-
-
0037216626
-
The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation
-
Yang H.S., Jansen A.P., Komar A.A., Zheng X., Merrick W.C., Costes S., et al. The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol Cell Biol 2003, 23:26-37.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 26-37
-
-
Yang, H.S.1
Jansen, A.P.2
Komar, A.A.3
Zheng, X.4
Merrick, W.C.5
Costes, S.6
-
102
-
-
33750325725
-
S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
-
Dorrello N.V., Peschiaroli A., Guardavaccaro D., Colburn N.H., Sherman N.E., Pagano M. S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 2006, 314:467-471.
-
(2006)
Science
, vol.314
, pp. 467-471
-
-
Dorrello, N.V.1
Peschiaroli, A.2
Guardavaccaro, D.3
Colburn, N.H.4
Sherman, N.E.5
Pagano, M.6
-
103
-
-
84871178729
-
Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis
-
Dennis M.D., Jefferson L.S., Kimball S.R. Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis. J Biol Chem 2012, 287:42890-42899.
-
(2012)
J Biol Chem
, vol.287
, pp. 42890-42899
-
-
Dennis, M.D.1
Jefferson, L.S.2
Kimball, S.R.3
-
104
-
-
33748924333
-
EIF3: a versatile scaffold for translation initiation complexes
-
Hinnebusch A.G. eIF3: a versatile scaffold for translation initiation complexes. Trends Biochem Sci 2006, 31:553-562.
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 553-562
-
-
Hinnebusch, A.G.1
-
105
-
-
77749299092
-
The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse
-
Csibi A., Cornille K., Leibovitch M.P., Poupon A., Tintignac L.A., Sanchez A.M., et al. The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse. PLoS ONE 2010, 5:e8994.
-
(2010)
PLoS ONE
, vol.5
, pp. e8994
-
-
Csibi, A.1
Cornille, K.2
Leibovitch, M.P.3
Poupon, A.4
Tintignac, L.A.5
Sanchez, A.M.6
-
106
-
-
34250378852
-
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry
-
Damoc E., Fraser C.S., Zhou M., Videler H., Mayeur G.L., Hershey J.W., et al. Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. Mol Cell Proteomics 2007, 6:1135-1146.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 1135-1146
-
-
Damoc, E.1
Fraser, C.S.2
Zhou, M.3
Videler, H.4
Mayeur, G.L.5
Hershey, J.W.6
-
107
-
-
84894256995
-
Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase
-
Martineau Y., Wang X., Alain T., Petroulakis E., Shahbazian D., Fabre B., et al. Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase. Mol Cell Biol 2014, 34:1046-1053.
-
(2014)
Mol Cell Biol
, vol.34
, pp. 1046-1053
-
-
Martineau, Y.1
Wang, X.2
Alain, T.3
Petroulakis, E.4
Shahbazian, D.5
Fabre, B.6
-
108
-
-
0032908981
-
A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development
-
Nielsen J., Christiansen J., Lykke-Andersen J., Johnsen A.H., Wewer U.M., Nielsen F.C. A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development. Mol Cell Biol 1999, 19:1262-1270.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1262-1270
-
-
Nielsen, J.1
Christiansen, J.2
Lykke-Andersen, J.3
Johnsen, A.H.4
Wewer, U.M.5
Nielsen, F.C.6
-
109
-
-
79958064675
-
MTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry
-
Dai N., Rapley J., Angel M., Yanik M.F., Blower M.D., Avruch J. mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry. Genes Dev 2011, 25:1159-1172.
-
(2011)
Genes Dev
, vol.25
, pp. 1159-1172
-
-
Dai, N.1
Rapley, J.2
Angel, M.3
Yanik, M.F.4
Blower, M.D.5
Avruch, J.6
-
110
-
-
84873488006
-
MTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts
-
Dai N., Christiansen J., Nielsen F.C., Avruch J. mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts. Genes Dev 2013, 27:301-312.
-
(2013)
Genes Dev
, vol.27
, pp. 301-312
-
-
Dai, N.1
Christiansen, J.2
Nielsen, F.C.3
Avruch, J.4
-
111
-
-
0002024553
-
The protein biosynthesis elongation cycle
-
CSHL Press, New York, N. Sonenberg, J.W. Hershey, M.B. Mathews (Eds.)
-
Merrick W.C., Nyborg J. The protein biosynthesis elongation cycle. Translational control of gene expression 2000, 89-125. CSHL Press, New York. N. Sonenberg, J.W. Hershey, M.B. Mathews (Eds.).
-
(2000)
Translational control of gene expression
, pp. 89-125
-
-
Merrick, W.C.1
Nyborg, J.2
-
112
-
-
0036438894
-
Regulation of peptide-chain elongation in mammalian cells
-
Browne G.J., Proud C.G. Regulation of peptide-chain elongation in mammalian cells. Eur J Biochem 2002, 269:5360-5368.
-
(2002)
Eur J Biochem
, vol.269
, pp. 5360-5368
-
-
Browne, G.J.1
Proud, C.G.2
-
113
-
-
0032535207
-
Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome
-
Pape T., Wintermeyer W., Rodnina M.V. Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome. EMBO J 1998, 17:7490-7497.
-
(1998)
EMBO J
, vol.17
, pp. 7490-7497
-
-
Pape, T.1
Wintermeyer, W.2
Rodnina, M.V.3
-
114
-
-
0037321497
-
After the ribosome structures: how does peptidyl transferase work?
-
Moore P.B., Steitz T.A. After the ribosome structures: how does peptidyl transferase work?. RNA 2003, 9:155-159.
-
(2003)
RNA
, vol.9
, pp. 155-159
-
-
Moore, P.B.1
Steitz, T.A.2
-
115
-
-
0030845290
-
Three tRNA binding sites in rabbit liver ribosomes and role of the intrinsic ATPase in 80S ribosomes from higher eukaryotes
-
El'skaya A.V., Ovcharenko G.V., Palchevskii S.S., Petrushenko Z.M., Triana-Alonso F.J., Nierhaus K.H. Three tRNA binding sites in rabbit liver ribosomes and role of the intrinsic ATPase in 80S ribosomes from higher eukaryotes. Biochemistry 1997, 36:10492-10497.
-
(1997)
Biochemistry
, vol.36
, pp. 10492-10497
-
-
El'skaya, A.V.1
Ovcharenko, G.V.2
Palchevskii, S.S.3
Petrushenko, Z.M.4
Triana-Alonso, F.J.5
Nierhaus, K.H.6
-
116
-
-
0023884601
-
Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation
-
Ryazanov A.G., Shestakova E.A., Natapov P.G. Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation. Nature 1988, 334:170-173.
-
(1988)
Nature
, vol.334
, pp. 170-173
-
-
Ryazanov, A.G.1
Shestakova, E.A.2
Natapov, P.G.3
-
117
-
-
0025003542
-
Functional properties of phosphorylated elongation factor 2
-
Carlberg U., Nilsson A., Nygard O. Functional properties of phosphorylated elongation factor 2. Eur J Biochem 1990, 191:639-645.
-
(1990)
Eur J Biochem
, vol.191
, pp. 639-645
-
-
Carlberg, U.1
Nilsson, A.2
Nygard, O.3
-
118
-
-
0024454195
-
The tumour promoter okadaic acid inhibits reticulocyte-lysate protein synthesis by increasing the net phosphorylation of elongation factor 2
-
Redpath N.T., Proud C.G. The tumour promoter okadaic acid inhibits reticulocyte-lysate protein synthesis by increasing the net phosphorylation of elongation factor 2. Biochem J 1989, 262:69-75.
-
(1989)
Biochem J
, vol.262
, pp. 69-75
-
-
Redpath, N.T.1
Proud, C.G.2
-
119
-
-
0034809193
-
Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes
-
Everett A.D., Stoops T.D., Nairn A.C., Brautigan D. Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes. Am J Physiol Heart Circ Physiol 2001, 281:H161-H167.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.281
, pp. H161-H167
-
-
Everett, A.D.1
Stoops, T.D.2
Nairn, A.C.3
Brautigan, D.4
-
120
-
-
0035881470
-
Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase
-
Wang X., Li W., Williams M., Terada N., Alessi D.R., Proud C.G. Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. EMBO J 2001, 20:4370-4379.
-
(2001)
EMBO J
, vol.20
, pp. 4370-4379
-
-
Wang, X.1
Li, W.2
Williams, M.3
Terada, N.4
Alessi, D.R.5
Proud, C.G.6
-
121
-
-
1642355123
-
A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin
-
Browne G.J., Proud C.G. A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin. Mol Cell Biol 2004, 24:2986-2997.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2986-2997
-
-
Browne, G.J.1
Proud, C.G.2
-
122
-
-
0037117409
-
Identification of a conserved motif required for mTOR signaling
-
Schalm S.S., Blenis J. Identification of a conserved motif required for mTOR signaling. Curr Biol 2002, 12:632-639.
-
(2002)
Curr Biol
, vol.12
, pp. 632-639
-
-
Schalm, S.S.1
Blenis, J.2
-
123
-
-
0035881737
-
A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta
-
Knebel A., Morrice N., Cohen P. A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta. EMBO J 2001, 20:4360-4369.
-
(2001)
EMBO J
, vol.20
, pp. 4360-4369
-
-
Knebel, A.1
Morrice, N.2
Cohen, P.3
-
124
-
-
41949107421
-
Cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner
-
Smith E.M., Proud C.G. cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner. EMBO J 2008, 27:1005-1016.
-
(2008)
EMBO J
, vol.27
, pp. 1005-1016
-
-
Smith, E.M.1
Proud, C.G.2
-
125
-
-
0032518567
-
Insulin stimulation of phosphorylation of elongation factor 1 (eEF-1) enhances elongation activity
-
Chang Y.W., Traugh J.A. Insulin stimulation of phosphorylation of elongation factor 1 (eEF-1) enhances elongation activity. Eur J Biochem 1998, 251:201-207.
-
(1998)
Eur J Biochem
, vol.251
, pp. 201-207
-
-
Chang, Y.W.1
Traugh, J.A.2
-
126
-
-
79958696694
-
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling
-
Hsu P.P., Kang S.A., Rameseder J., Zhang Y., Ottina K.A., Lim D., et al. The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 2011, 332:1317-1322.
-
(2011)
Science
, vol.332
, pp. 1317-1322
-
-
Hsu, P.P.1
Kang, S.A.2
Rameseder, J.3
Zhang, Y.4
Ottina, K.A.5
Lim, D.6
-
127
-
-
79958696336
-
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling
-
Yu Y., Yoon S.O., Poulogiannis G., Yang Q., Ma X.M., Villen J., et al. Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 2011, 332:1322-1326.
-
(2011)
Science
, vol.332
, pp. 1322-1326
-
-
Yu, Y.1
Yoon, S.O.2
Poulogiannis, G.3
Yang, Q.4
Ma, X.M.5
Villen, J.6
-
128
-
-
79956322553
-
Global quantification of mammalian gene expression control
-
Schwanhausser B., Busse D., Li N., Dittmar G., Schuchhardt J., Wolf J., et al. Global quantification of mammalian gene expression control. Nature 2011, 473:337-342.
-
(2011)
Nature
, vol.473
, pp. 337-342
-
-
Schwanhausser, B.1
Busse, D.2
Li, N.3
Dittmar, G.4
Schuchhardt, J.5
Wolf, J.6
-
129
-
-
84899550455
-
Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources
-
Li G.W., Burkhardt D., Gross C., Weissman J.S. Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell 2014, 157:624-635.
-
(2014)
Cell
, vol.157
, pp. 624-635
-
-
Li, G.W.1
Burkhardt, D.2
Gross, C.3
Weissman, J.S.4
-
130
-
-
50649084799
-
All translation elongation factors and the e, f, and h subunits of translation initiation factor 3 are encoded by 5'-terminal oligopyrimidine (TOP) mRNAs
-
Iadevaia V., Caldarola S., Tino E., Amaldi F., Loreni F. All translation elongation factors and the e, f, and h subunits of translation initiation factor 3 are encoded by 5'-terminal oligopyrimidine (TOP) mRNAs. RNA 2008, 14:1730-1736.
-
(2008)
RNA
, vol.14
, pp. 1730-1736
-
-
Iadevaia, V.1
Caldarola, S.2
Tino, E.3
Amaldi, F.4
Loreni, F.5
-
131
-
-
0036125672
-
The human ribosomal protein genes: sequencing and comparative analysis of 73 genes
-
Yoshihama M., Uechi T., Asakawa S., Kawasaki K., Kato S., Higa S., et al. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. Genome Res 2002, 12:379-390.
-
(2002)
Genome Res
, vol.12
, pp. 379-390
-
-
Yoshihama, M.1
Uechi, T.2
Asakawa, S.3
Kawasaki, K.4
Kato, S.5
Higa, S.6
-
132
-
-
0035882103
-
The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB
-
Biondi R.M., Kieloch A., Currie R.A., Deak M., Alessi D.R. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB. EMBO J 2001, 20(16):4380-4390.
-
(2001)
EMBO J
, vol.20
, Issue.16
, pp. 4380-4390
-
-
Biondi, R.M.1
Kieloch, A.2
Currie, R.A.3
Deak, M.4
Alessi, D.R.5
|