Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

Toxicology in Vitro

Volumn 29, Issue 1, 2015, Pages 259-270

  Reisinger, Kerstin ^a   Hoffmann, Sebastian ^b   Alépée, Nathalie ^c   Ashikaga, Takao ^d   Barroso, Joao ^e,x   Elcombe, Cliff ^f   Gellatly, Nicola ^g   Galbiati, Valentina ^h   Gibbs, Susan ⁱ   Groux, Hervé ^j   Hibatallah, Jalila ^k   Keller, Donald ^l   Kern, Petra ^m   Klaric, Martina ^e   Kolle, Susanne ⁿ   Kuehnl, Jochen ^o   Lambrechts, Nathalie ^p   Lindstedt, Malin ^q   Millet, Marion ^r   Martinozzi Teissier, Silvia ^c   Natsch, Andreas ^s   Petersohn, Dirk ^a   Pike, Ian ^t   Sakaguchi, Hitoshi ^u   Schepky, Andreas ^o   Tailhardat, Magalie ^v   Templier, Marie ^r   Van Vliet, Erwin ^w   Maxwell, Gavin ^g   more..

^a HENKEL KGAA   (Germany)

^b Seh Consulting + Services   (Germany)

^c L'Oréal Research Center   (France)

^d SHISEIDO RESEARCH CENTER   (Japan)

^e Cosmetics Europe ^*  (Belgium)

^f CXR Biosciences Ltd   (United Kingdom)

^g UNILEVER RESEARCH   (United Kingdom)

^h UNIVERSITY OF MILAN   (Italy)

ⁱ VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^j Les Cyclades   (France)

^k Chanel   (France)

^l CYPROTEX DISCOVERY LTD   (United Kingdom)

^m PROCTER AND GAMBLE COMPANY   (United States)

ⁿ BASF SE   (Germany)

^o BEIERSDORF AG   (Germany)

^p FLEMISH INSTITUTE FOR TECHNOLOGICAL RESEARCH VITO   (Belgium)

^q LUND UNIVERSITY   (Sweden)

^r INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^s GIVAUDAN SCHWEIZ AG   (Switzerland)

^t Proteome Sciences plc   (United Kingdom)

^u KAO CORPORATION   (Japan)

^v Parfums Christian Dior   (France)

^w Services and Consultation on Alternative Methods (SeCAM)   (Switzerland)

^x EUROPEAN COMMISSION   (Belgium)

more..

Author keywords

Adverse outcome pathways; Non animal test methods; Safety assessment; Skin sensitisation; Testing strategy

Indexed keywords

COSMETIC; INTERLEUKIN 18;

ANIMAL TESTING ALTERNATIVE; AREC32 CELL LINE ASSAY; ARTICLE; ASSAY; BIOAVAILABILITY; CELL ASSAY; DATA ANALYSIS; DIRECT PEPTIDE REACTIVITY ASSAY; EPIDERMAL EQUIVALENT POTENCY ASSAY; EVALUATION STUDY; EXPOSURE; GENOMIC ALLERGEN RAPID DETECTION ASSAY; HUMAN; HUMAN CELL LINE ACTIVATION TEST; IN VITRO STUDY; KERATINOSENS TEST METHOD; LUSENS ASSAY; METABOLISM; METHODOLOGY; MODIFIED MYELOID U937 SKIN SENSITISATION TEST; MYELOID U937 SKIN SENSITISATION TEST; NCTC 2544 IL 18 ASSAY; OUTCOME ASSESSMENT; PERIPHERAL BLOOD MONOCYTE DERIVED DENDRITIC CELL ASSAY; PEROXIDASE PEPTIDE REACTIVITY ASSAY; PROTEIN REACTIVITY TEST; RISK ASSESSMENT; SENCEETOX METHOD; SENS IS METHOD; SENSIDERM TMT SRM 10 PLEX; SKIN SENSITIZATION; STANDARDIZATION; VITOSENS ASSAY; WORKSHOP; CELL LINE; DERMATITIS, ALLERGIC CONTACT; DRUG EFFECTS; EPIDERMIS; KERATINOCYTE; PROCEDURES; SKIN; U937 CELL LINE;

ANIMALIA;

ANIMAL TESTING ALTERNATIVES; CELL LINE; COSMETICS; DERMATITIS, ALLERGIC CONTACT; EPIDERMIS; HUMANS; IN VITRO TECHNIQUES; INTERLEUKIN-18; KERATINOCYTES; RISK ASSESSMENT; SKIN; U937 CELLS;

EID: 84912006576     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2014.10.018     Document Type: Article

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