Putting the parts together: Combining in vitro methods to test for skin sensitizing potentials

Regulatory Toxicology and Pharmacology

Volumn 63, Issue 3, 2012, Pages 489-504

  Bauch, Caroline ^a,b   Kolle, Susanne N ^a   Ramirez, Tzutzuy ^a   Eltze, Tobias ^a   Fabian, Eric ^a   Mehling, Annette ^a   Teubner, Wera ^c   van Ravenzwaay, Bennard ^a   Landsiedel, Robert ^a  

^a BASF SE   (Germany)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c CIBA GEIGY LTD   (Switzerland)

Author keywords

Alternative methods; DPRA; EU cosmetics regulation; H CLAT; In vitro; KeratinoSens ; LuSens; MMUSST; Prediction model; Skin sensitization

Indexed keywords

1,4 BENZOQUINONE; 2 PROPANOL; ANILINE; BENZYLIDENEACETONE; BUTANOL; CITRAL; COBALT CHLORIDE; DODECYL SULFATE SODIUM; ETHYLENEDIAMINE; FORMALDEHYDE; FUMARIC ACID; GALLIC ACID PROPYL ESTER; GLUCOSE; GLYCEROL; HEXANE; HYDROXYCITRONELLAL; ISOEUGENOL; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MALEIC ACID DIETHYL ESTER; OXAZOLONE; PHENYLENEDIAMINE; PHTHALIC ANHYDRIDE; PYRIDINE; SULFANILAMIDE; TARTARIC ACID; TRANSCRIPTION FACTOR NRF2; TRINITROBENZENESULFONIC ACID; XYLENE;

ARTICLE; CELL ACTIVATION; CELL ASSAY; COMPUTER MODEL; DENDRITIC CELL; HUMAN; IN VITRO STUDY; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RELIABILITY; SIGNAL TRANSDUCTION; SKIN SENSITIZATION;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; ANIMALS; BIOLOGICAL ASSAY; DERMATITIS, ALLERGIC CONTACT; HUMANS; REPRODUCIBILITY OF RESULTS; SKIN IRRITANCY TESTS;

ANIMALIA;

EID: 84863504400     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2012.05.013     Document Type: Article

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