-
1
-
-
0037336383
-
P38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochlorobenzene
-
Aiba S., Manome H., Nakagawa S., Mollah Z.U., Mizuashi M., Ohtani T., Yoshino Y., Tagami H. p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochlorobenzene. J. Invest. Dermatol. 2003, 120:390-399.
-
(2003)
J. Invest. Dermatol.
, vol.120
, pp. 390-399
-
-
Aiba, S.1
Manome, H.2
Nakagawa, S.3
Mollah, Z.U.4
Mizuashi, M.5
Ohtani, T.6
Yoshino, Y.7
Tagami, H.8
-
2
-
-
38949124339
-
IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis
-
Antonopoulos C., Cumberbatch M., Mee J.B., Dearman R.J., Wei X.Q., Liew F.Y., Kimber I., Groves R.W. IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis. J. Leukoc. Biol. 2008, 83:361-367.
-
(2008)
J. Leukoc. Biol.
, vol.83
, pp. 361-367
-
-
Antonopoulos, C.1
Cumberbatch, M.2
Mee, J.B.3
Dearman, R.J.4
Wei, X.Q.5
Liew, F.Y.6
Kimber, I.7
Groves, R.W.8
-
3
-
-
0035869634
-
A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers
-
Arrighi J.F., Rebsamen M., Rousset F., Kindler V., Hauser C. A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers. J. Immunol. 2001, 166:3837-3845.
-
(2001)
J. Immunol.
, vol.166
, pp. 3837-3845
-
-
Arrighi, J.F.1
Rebsamen, M.2
Rousset, F.3
Kindler, V.4
Hauser, C.5
-
4
-
-
47249087716
-
Skin irritation and sensitization: mechanisms and new approaches for risk assessment
-
Basketter D., Darlenski R., Fluhr J.W. Skin irritation and sensitization: mechanisms and new approaches for risk assessment. Skin Pharmacol. Physiol. 2008, 21:191-202.
-
(2008)
Skin Pharmacol. Physiol.
, vol.21
, pp. 191-202
-
-
Basketter, D.1
Darlenski, R.2
Fluhr, J.W.3
-
5
-
-
68949144888
-
Updating the skin sensitization in vitro data assessment paradigm in 2009
-
Basketter D.A., Kimber I. Updating the skin sensitization in vitro data assessment paradigm in 2009. J. Appl. Toxicol. 2009, 29:545-550.
-
(2009)
J. Appl. Toxicol.
, vol.29
, pp. 545-550
-
-
Basketter, D.A.1
Kimber, I.2
-
6
-
-
10044279431
-
Implication of the MAPK pathways in the maturation of human dendritic cells induced by nickel and TNF-alpha
-
Boisleve F., Kerdine-Romer S., Pallardy M. Implication of the MAPK pathways in the maturation of human dendritic cells induced by nickel and TNF-alpha. Toxicology 2005, 206:233-244.
-
(2005)
Toxicology
, vol.206
, pp. 233-244
-
-
Boisleve, F.1
Kerdine-Romer, S.2
Pallardy, M.3
-
7
-
-
69549119940
-
Molecular mechanisms involved in inflammasome activation
-
Bryant C., Fitzgerald K.A. Molecular mechanisms involved in inflammasome activation. Trends Cell Biol. 2009, 19:455-464.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 455-464
-
-
Bryant, C.1
Fitzgerald, K.A.2
-
8
-
-
67649359509
-
Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens
-
Corsini E., Mitjans M., Galbiati V., Lucchi L., Galli C.L., Marinovich M. Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens. Toxicol. In Vitro 2009, 23:789-796.
-
(2009)
Toxicol. In Vitro
, vol.23
, pp. 789-796
-
-
Corsini, E.1
Mitjans, M.2
Galbiati, V.3
Lucchi, L.4
Galli, C.L.5
Marinovich, M.6
-
9
-
-
0032555773
-
Selective induction of cell-associated interleukin-1alpha in murine keratinocytes by chemical allergens
-
Corsini E., Primavera A., Marinovich M., Galli C.L. Selective induction of cell-associated interleukin-1alpha in murine keratinocytes by chemical allergens. Toxicology 1998, 129:193-200.
-
(1998)
Toxicology
-
-
Corsini, E.1
Primavera, A.2
Marinovich, M.3
Galli, C.L.4
-
10
-
-
70449579357
-
Immunotoxicology: opportunities for non-animal test development
-
Corsini E., Roggen E.L. Immunotoxicology: opportunities for non-animal test development. Altern. Lab. Anim. 2009, 37:387-397.
-
(2009)
Altern. Lab. Anim.
, vol.37
, pp. 387-397
-
-
Corsini, E.1
Roggen, E.L.2
-
11
-
-
0342905089
-
Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen
-
Coutant K.D., de Fraissinette A.B., Cordier A., Ulrich P. Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen. Toxicol. Sci. 1999, 52:189-98.
-
(1999)
Toxicol. Sci.
-
-
Coutant, K.D.1
de Fraissinette, A.B.2
Cordier, A.3
Ulrich, P.4
-
12
-
-
0035067261
-
Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-alpha- and IL-1beta-dependent mechanism
-
Cumberbatch M., Dearman R.J., Antonopoulos C., Groves R.W., Kimber I. Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-alpha- and IL-1beta-dependent mechanism. Immunology 2001, 102:323-330.
-
(2001)
Immunology
, vol.102
, pp. 323-330
-
-
Cumberbatch, M.1
Dearman, R.J.2
Antonopoulos, C.3
Groves, R.W.4
Kimber, I.5
-
13
-
-
0023766213
-
Comparison of methods for the estimation of the thickness of ultrathin tissue sections
-
De Groot D.M. Comparison of methods for the estimation of the thickness of ultrathin tissue sections. J. Microsc. 1988, 151:23-42.
-
(1988)
J. Microsc.
, vol.151
, pp. 23-42
-
-
De Groot, D.M.1
-
14
-
-
63649098913
-
Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound
-
dos Santos G.G., Reinders J., Ouwehand K., Rustemeyer T., Scheper R.J., Gibbs S. Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound. Toxicol. Appl. Pharmacol. 2009, 236:372-382.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.236
, pp. 372-382
-
-
dos Santos, G.G.1
Reinders, J.2
Ouwehand, K.3
Rustemeyer, T.4
Scheper, R.J.5
Gibbs, S.6
-
15
-
-
77952950728
-
Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro
-
Emter R., Ellis G., Natsch A. Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro. Toxicol. Appl. Pharmacol. 2010, 245:281-290.
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.245
, pp. 281-290
-
-
Emter, R.1
Ellis, G.2
Natsch, A.3
-
16
-
-
0026570156
-
Early molecular events in the induction phase of contact sensitivity
-
Enk A.H., Katz S.I. Early molecular events in the induction phase of contact sensitivity. Proc. Natl Acad. Sci. USA 1992, 89:1398-1402.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 1398-1402
-
-
Enk, A.H.1
Katz, S.I.2
-
17
-
-
78649260280
-
Present and future of in vitro immunotoxicology in drug development
-
Galbiati V., Mitjans M., Corsini E. Present and future of in vitro immunotoxicology in drug development. J. Immunotoxicol. 2010, 1-13.
-
(2010)
J. Immunotoxicol.
, pp. 1-13
-
-
Galbiati, V.1
Mitjans, M.2
Corsini, E.3
-
18
-
-
0023019005
-
Use of MTT colorimetric assay to measure cell activation
-
Gerlier D., Thomasset N. Use of MTT colorimetric assay to measure cell activation. J. Immunol. Methods 1986, 94:57-63.
-
(1986)
J. Immunol. Methods
, vol.94
, pp. 57-63
-
-
Gerlier, D.1
Thomasset, N.2
-
19
-
-
33750523632
-
NF-kappaB activation by reactive oxygen species: fifteen years later
-
Gloire G., Legrand-Poels S., Piette J. NF-kappaB activation by reactive oxygen species: fifteen years later. Biochem. Pharmacol. 2006, 72:1493-1505.
-
(2006)
Biochem. Pharmacol.
, vol.72
, pp. 1493-1505
-
-
Gloire, G.1
Legrand-Poels, S.2
Piette, J.3
-
20
-
-
44449136379
-
Endogenous IL-18 in experimentally induced asthma affects cytokine serum levels but is irrelevant for clinical symptoms
-
Hartwig C., Tschernig T., Mazzega M., Braun A., Neumann D. Endogenous IL-18 in experimentally induced asthma affects cytokine serum levels but is irrelevant for clinical symptoms. Cytokine 2008, 42:298-305.
-
(2008)
Cytokine
, vol.42
, pp. 298-305
-
-
Hartwig, C.1
Tschernig, T.2
Mazzega, M.3
Braun, A.4
Neumann, D.5
-
21
-
-
0029561902
-
Anti-inflammatory properties of Go 6850: a selective inhibitor of protein kinase C
-
Jacobson P.B., Kuchera S.L., Metz A., Schachtele C., Imre K., Schrier D.J. Anti-inflammatory properties of Go 6850: a selective inhibitor of protein kinase C. J. Pharmacol. Exp. Ther. 1995, 275:995-1002.
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.275
, pp. 995-1002
-
-
Jacobson, P.B.1
Kuchera, S.L.2
Metz, A.3
Schachtele, C.4
Imre, K.5
Schrier, D.J.6
-
22
-
-
76749088358
-
Pathological roles of MAPK signaling pathways in human diseases
-
Kim E.K., Choi E.J. Pathological roles of MAPK signaling pathways in human diseases. Biochim. Biophys. Acta 2010, 1802:396-405.
-
(2010)
Biochim. Biophys. Acta
, vol.1802
, pp. 396-405
-
-
Kim, E.K.1
Choi, E.J.2
-
23
-
-
77449154369
-
In vitro testing for direct immunotoxicity: state of the art
-
Lankveld D.P., Van Loveren H., Baken K.A., Vandebriel R.J. In vitro testing for direct immunotoxicity: state of the art. Methods Mol. Biol. 2010, 598:401-423.
-
(2010)
Methods Mol. Biol.
, vol.598
, pp. 401-423
-
-
Lankveld, D.P.1
Van Loveren, H.2
Baken, K.A.3
Vandebriel, R.J.4
-
24
-
-
0028933640
-
Nickel and skin irritants up-regulate tumor necrosis factor-alpha mRNA in keratinocytes by different but potentially synergistic mechanisms
-
Lisby S., Muller K.M., Jongeneel C.V., Saurat J.H., Hauser C. Nickel and skin irritants up-regulate tumor necrosis factor-alpha mRNA in keratinocytes by different but potentially synergistic mechanisms. Int. Immunol. 1995, 7:343-352.
-
(1995)
Int. Immunol.
, vol.7
, pp. 343-352
-
-
Lisby, S.1
Muller, K.M.2
Jongeneel, C.V.3
Saurat, J.H.4
Hauser, C.5
-
25
-
-
77749304032
-
Signaling by ROS drives inflammasome activation
-
Martinon F. Signaling by ROS drives inflammasome activation. Eur. J. Immunol. 2010, 40:616-619.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 616-619
-
-
Martinon, F.1
-
27
-
-
33846952883
-
Differential phosphorylation of MAPK isoforms in keratinocyte cell line by contact allergens and irritant
-
Mehrotra P., Upadhyaya S., Sinkar V.P., Banerjee G., Mishra K.P. Differential phosphorylation of MAPK isoforms in keratinocyte cell line by contact allergens and irritant. Toxicol. Mech. Methods 2007, 17:101-107.
-
(2007)
Toxicol. Mech. Methods
, vol.17
, pp. 101-107
-
-
Mehrotra, P.1
Upadhyaya, S.2
Sinkar, V.P.3
Banerjee, G.4
Mishra, K.P.5
-
28
-
-
38549091168
-
Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THP-1 cells
-
Mitjans M., Viviani B., Lucchi L., Galli C.L., Marinovich M., Corsini E. Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THP-1 cells. Toxicol. In Vitro 2008, 22:386-395.
-
(2008)
Toxicol. In Vitro
, vol.22
, pp. 386-395
-
-
Mitjans, M.1
Viviani, B.2
Lucchi, L.3
Galli, C.L.4
Marinovich, M.5
Corsini, E.6
-
29
-
-
0028130251
-
Identification and induction of human keratinocyte-derived IL-12
-
Muller G., Saloga J., Germann T., Bellinghausen I., Mohamadzadeh M., Knop J., Enk A.H. Identification and induction of human keratinocyte-derived IL-12. J. Clin. Invest. 1994, 94:1799-1805.
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 1799-1805
-
-
Muller, G.1
Saloga, J.2
Germann, T.3
Bellinghausen, I.4
Mohamadzadeh, M.5
Knop, J.6
Enk, A.H.7
-
30
-
-
39149086011
-
Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals
-
Natsch A., Emter R. Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals. Toxicol. Sci. 2008, 102:110-119.
-
(2008)
Toxicol. Sci.
, vol.102
, pp. 110-119
-
-
Natsch, A.1
Emter, R.2
-
32
-
-
67650901555
-
Allergic and irritant contact dermatitis
-
Nosbaum A., Vocanson M., Rozieres A., Hennino A., Nicolas J.F. Allergic and irritant contact dermatitis. Eur. J. Dermatol. 2009, 19(4):325-332.
-
(2009)
Eur. J. Dermatol.
, vol.19
, Issue.4
, pp. 325-332
-
-
Nosbaum, A.1
Vocanson, M.2
Rozieres, A.3
Hennino, A.4
Nicolas, J.F.5
-
33
-
-
0028845730
-
Cloning of a new cytokine that induces IFN-gamma production by T cells
-
Okamura H., Tsutsi H., Komatsu T., Yutsudo M., Hakura A., Tanimoto T., Torigoe K., Okura T., Nukada Y., Hattori K., et al. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature 1995, 378:88-91.
-
(1995)
Nature
, vol.378
, pp. 88-91
-
-
Okamura, H.1
Tsutsi, H.2
Komatsu, T.3
Yutsudo, M.4
Hakura, A.5
Tanimoto, T.6
Torigoe, K.7
Okura, T.8
Nukada, Y.9
Hattori, K.10
-
34
-
-
0027378941
-
Compositae dermatitis in a Danish dermatology department in 1 year (II). Clinical features in patients with Compositae contact allergy
-
Paulsen E., Andersen K.E. Compositae dermatitis in a Danish dermatology department in 1 year (II). Clinical features in patients with Compositae contact allergy. Contact Dermatitis 1993, 29:195-201.
-
(1993)
Contact Dermatitis
, vol.29
, pp. 195-201
-
-
Paulsen, E.1
Andersen, K.E.2
-
35
-
-
0025295532
-
Nickel-keratinocyte interaction: a possible role in sensitization
-
Picardo M., Zompetta C., De Luca C., Cristaudo A., Cannistraci C., Faggioni A., Santucci B. Nickel-keratinocyte interaction: a possible role in sensitization. Br. J. Dermatol. 1990, 122:729-735.
-
(1990)
Br. J. Dermatol.
, vol.122
, pp. 729-735
-
-
Picardo, M.1
Zompetta, C.2
De Luca, C.3
Cristaudo, A.4
Cannistraci, C.5
Faggioni, A.6
Santucci, B.7
-
36
-
-
4544235002
-
Non-invasive biomarkers of oxidative stress: reproducibility and methodological issues
-
Rahman I., Biswas S.K. Non-invasive biomarkers of oxidative stress: reproducibility and methodological issues. Redox Rep. 2004, 9:125-143.
-
(2004)
Redox Rep.
, vol.9
, pp. 125-143
-
-
Rahman, I.1
Biswas, S.K.2
-
38
-
-
0032843068
-
Intracellular production of interleukin-18 in human epithelial-like cell lines is enhanced by hyperosmotic stress in vitro
-
Takeuchi M., Okura T., Mori T., Akita K., Ohta T., Ikeda M., Ikegami H., Kurimoto M. Intracellular production of interleukin-18 in human epithelial-like cell lines is enhanced by hyperosmotic stress in vitro. Cell Tissue Res. 1999, 297:467-473.
-
(1999)
Cell Tissue Res.
, vol.297
, pp. 467-473
-
-
Takeuchi, M.1
Okura, T.2
Mori, T.3
Akita, K.4
Ohta, T.5
Ikeda, M.6
Ikegami, H.7
Kurimoto, M.8
-
39
-
-
9644266698
-
Induction of allergic inflammation by interleukin-18 in experimental animal models
-
Tsutsui H., Yoshimoto T., Hayashi N., Mizutani H., Nakanishi K. Induction of allergic inflammation by interleukin-18 in experimental animal models. Immunol. Rev. 2004, 202:115-138.
-
(2004)
Immunol. Rev.
, vol.202
, pp. 115-138
-
-
Tsutsui, H.1
Yoshimoto, T.2
Hayashi, N.3
Mizutani, H.4
Nakanishi, K.5
-
40
-
-
17144373652
-
Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1alpha and IL-18 production by a murine and human keratinocyte cell line
-
Van Och F.M., Van Loveren H., Van Wolfswinkel J.C., Machielsen A.J., Vandebriel R.J. Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1alpha and IL-18 production by a murine and human keratinocyte cell line. Toxicology 2005, 210:95-109.
-
(2005)
Toxicology
, vol.210
, pp. 95-109
-
-
Van Och, F.M.1
Van Loveren, H.2
Van Wolfswinkel, J.C.3
Machielsen, A.J.4
Vandebriel, R.J.5
-
41
-
-
77955871452
-
Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds
-
Vandebriel R.J., Pennings J.L., Baken K.A., Pronk T.E., Boorsma A., Gottschalk R., Van Loveren H. Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds. Toxicol. Sci. 2010, 117:81-89.
-
(2010)
Toxicol. Sci.
-
-
Vandebriel, R.J.1
Pennings, J.L.2
Baken, K.A.3
Pronk, T.E.4
Boorsma, A.5
Gottschalk, R.6
Van Loveren, H.7
-
42
-
-
17144414196
-
In vitro assessment of sensitizing activity of low molecular weight compounds
-
Vandebriel R.J., Van Och F.M., van Loveren H. In vitro assessment of sensitizing activity of low molecular weight compounds. Toxicol. Appl. Pharmacol. 2005, 207:142-148.
-
(2005)
Toxicol. Appl. Pharmacol.
, vol.207
, pp. 142-148
-
-
Vandebriel, R.J.1
Van Och, F.M.2
van Loveren, H.3
|